Lipids trigger a conformational switch that regulates Signal Recognition Particle (SRP)-mediated protein targeting

Journal of Biological Chemistry

Volumn 286, Issue 26, 2011, Pages 23489-23497

  Stjepanovic, Goran ^a   Kapp, Katja ^a,b   Bange, Gert ^a   Graf, Christian ^a,c   Parlitz, Richard ^a   Wild, Klemens ^a   Mayer, Matthias P ^a   Sinning, Irmgard ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANIONIC PHOSPHOLIPIDS; COIL-HELIX TRANSITION; CONFORMATIONAL SWITCHES; GTPASES; HETERODIMERS; LIPID-PROTEIN INTERACTIONS; PROTEIN TARGETING; SIGNAL RECOGNITION PARTICLES;

BIOLOGICAL MEMBRANES; CYTOLOGY; MEMBRANES; PHOSPHOLIPIDS; SIGNAL PROCESSING;

PROTEINS;

DOCKING PROTEIN; FTSY PROTEIN; GUANOSINE TRIPHOSPHATASE; PHOSPHOLIPID; SIGNAL RECOGNITION PARTICLE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN LIPID INTERACTION; PROTEIN TARGETING; PROTEIN UNFOLDING;

BACTERIAL PROTEINS; CELL MEMBRANE; ESCHERICHIA COLI; GTP PHOSPHOHYDROLASES; PHOSPHOLIPIDS; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL RECOGNITION PARTICLE;

EID: 79959557410     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.212340     Document Type: Article

References (49)

1. Facey, S. J., and Kuhn, A. (2010) Cell. Mol. Life Sci. 67, 2343-2362
2. Cross, B. C., Sinning, I., Luirink, J., and High, S. (2009) Nat. Rev. Mol. Cell Biol. 10, 255-264
3. Grudnik, P., Bange, G., and Sinning, I. (2009) Biol. Chem. 390, 775-782
4. Wilson, C., Connolly, T., Morrison, T., and Gilmore, R. (1988) J. Cell Biol. 107, 69-77
5. Powers, T., and Walter, P. (1995) Science 269, 1422-1424
6. Mircheva, M., Boy, D., Weiche, B., Hucke, F., Graumann, P., and Koch, H. G. (2009) BMC Biol. 7, 76
7. Montoya, G., Svensson, C., Luirink, J., and Sinning, I. (1997) Nature 385, 365-368
8. Freymann, D. M., Keenan, R. J., Stroud, R. M., and Walter, P. (1997) Nature 385, 361-364
9. de Leeuw, E., te Kaat, K., Moser, C., Menestrina, G., Demel, R., de Kruijff, B., Oudega, B., Luirink, J., and Sinning, I. (2000) EMBO J. 19, 531-541
10. Weiche, B., Bürk, J., Angelini, S., Schiltz, E., Thumfart, J. O., and Koch, H. G. (2008) J. Mol. Biol. 377, 761-773
11. Eitan, A., and Bibi, E. (2004) J. Bacteriol. 186, 2492-2494
12. Valent, Q. A., Scotti, P. A., High, S., de Gier, J. W., von Heijne, G., Lentzen, G., Wintermeyer, W., Oudega, B., and Luirink, J. (1998) EMBO J. 17, 2504-2512
13. Bahari, L., Parlitz, R., Eitan, A., Stjepanovic, G., Bochkareva, E. S., Sinning, I., and Bibi, E. (2007) J. Biol. Chem. 282, 32168-32175
14. Lam, V. Q., Akopian, D., Rome, M., Henningsen, D., and Shan, S. O. (2010) J. Cell Biol. 190, 623-635
15. Parlitz, R., Eitan, A., Stjepanovic, G., Bahari, L., Bange, G., Bibi, E., and Sinning, I. (2007) J. Biol. Chem. 282, 32176-32184
16. Erez, E., Stjepanovic, G., Zelazny, A. M., Brugger, B., Sinning, I., and Bibi, E. (2010) J. Biol. Chem. 285, 40508-40514
17. Montoya, G., Svensson, C., Luirink, J., and Sinning, I. (1997) Proteins 28, 285-288
18. (1994) Acta Crystallogr. D Biol. Crystallogr. 50, 760-763
19. Emsley, P., Lohkamp, B., Scott, W. G., and Cowtan, K. (2010) Acta Crystallogr. D Biol. Crystallogr. 66, 486-501
20. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta Crystallogr. D Biol. Crystallogr. 53, 240-255
21. Adams, P. D., Afonine, P. V., Bunkóczi, G., Chen, V. B., Davis, I. W., Echols, N., Headd, J. J., Hung, L. W., Kapral, G. J., Grosse-Kunstleve, R. W., Mc- Coy, A. J., Moriarty, N. W., Oeffner, R., Read, R. J., Richardson, D. C., Richardson, J. S., Terwilliger, T. C., and Zwart, P. H. (2010) Acta Crystallogr. D Biol. Crystallogr. 66, 213-221
22. Rist, W., Graf, C., Bukau, B., and Mayer, M. P. (2006) J. Biol. Chem. 281, 16493-16501
23. Bozkurt, G., Stjepanovic, G., Vilardi, F., Amlacher, S., Wild, K., Bange, G., Favaloro, V., Rippe, K., Hurt, E., Dobberstein, B., and Sinning, I. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 21131-21136
24. Zhang, Z., Post, C. B., and Smith, D. L. (1996) Biochemistry 35, 779-791
25. Powers, T., and Walter, P. (1997) EMBO J. 16, 4880-4886
26. Shan, S. O., Chandrasekar, S., and Walter, P. (2007) J. Cell Biol. 178, 611-620
27. Samuelsson, T., and Olsson, M. (1993) Nucleic Acids Res. 21, 847-853
28. Engen, J. R., and Smith, D. L. (2001) Anal. Chem. 73, 256A-265A
29. Englander, S. W. (2000) Annu. Rev. Biophys. Biomol. Struct. 29, 213-238
30. Englander, S. W., and Kallenbach, N. R. (1983) Q. Rev. Biophys. 16, 521-655
31. Rist, W., Jørgensen, T. J., Roepstorff, P., Bukau, B., and Mayer, M. P. (2003) J. Biol. Chem. 278, 51415-51421
32. Wales, T. E., and Engen, J. R. (2006) Mass Spectrom. Rev. 25, 158-170
33. Egea, P. F., Shan, S. O., Napetschnig, J., Savage, D. F., Walter, P., and Stroud, R. M. (2004) Nature 427, 215-221
34. Focia, P. J., Shepotinovskaya, I. V., Seidler, J. A., and Freymann, D. M. (2004) Science 303, 373-377
35. Neher, S. B., Bradshaw, N., Floor, S. N., Gross, J. D., and Walter, P. (2008) Nat. Struct. Mol. Biol. 15, 916-923
36. Millman, J. S., Qi, H. Y., Vulcu, F., Bernstein, H. D., and Andrews, D. W. (2001) J. Biol. Chem. 276, 25982-25989
37. Vanounou, S., Parola, A. H., and Fishov, I. (2003) Mol. Microbiol. 49, 1067-1079
38. Gold, V. A., Robson, A., Bao, H., Romantsov, T., Duong, F., and Collinson, I. (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 10044-10049
39. Mileykovskaya, E., Fishov, I., Fu, X., Corbin, B. D., Margolin, W., and Dowhan, W. (2003) J. Biol. Chem. 278, 22193-22198
40. Szeto, T. H., Rowland, S. L., Habrukowich, C. L., and King, G. F. (2003) J. Biol. Chem. 278, 40050-40056
41. Bernstein, L. S., Grillo, A. A., Loranger, S. S., and Linder, M. E. (2000) J. Biol. Chem. 275, 18520-18526
42. Zhang, X., Schaffitzel, C., Ban, N., and Shan, S. O. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 1754-1759
43. Wild, K., Halic, M., Sinning, I., and Beckmann, R. (2004) Nat. Struct. Mol. Biol. 11, 1049-1053
44. Halic, M., Blau, M., Becker, T., Mielke, T., Pool, M. R., Wild, K., Sinning, I., and Beckmann, R. (2006) Nature 444, 507-511
45. Herskovits, A. A., Seluanov, A., Rajsbaum, R., ten Hagen-Jongman, C. M., Henrichs, T., Bochkareva, E. S., Phillips, G. J., Probst, F. J., Nakae, T., Ehrmann, M., Luirink, J., and Bibi, E. (2001) EMBO Rep. 2, 1040-1046
46. Bibi, E. (2011) Biochim. Biophys. Acta 1808, 841-850
47. Young, J. C., Ursini, J., Legate, K. R., Miller, J. D., Walter, P., and Andrews, D. W. (1995) J. Biol. Chem. 270, 15650-15657
48. Schlenker, O., Hendricks, A., Sinning, I., and Wild, K. (2006) J. Biol. Chem. 281, 8898-8906
49. Schwartz, T., and Blobel, G. (2003) Cell 112, 793-803