Association of polyalanine and polyglutamine coiled coils mediates expansion disease-related protein aggregation and dysfunction

Human Molecular Genetics

Volumn 23, Issue 13, 2014, Pages 3402-3420

  Pelassa, Ilaria ^a   Corà, Davide ^a   Cesano, Federico ^a   Monje, Francisco J ^b   Montarolo, Pier Giorgio ^a,c   Fiumara, Ferdinando ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c National Institute of Neuroscience   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE DERIVATIVE; POLYALANINE; POLYGLUTAMINE; PROTEOME; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; PEPTIDE; PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; BIOINFORMATICS; CAENORHABDITIS ELEGANS; CAG REPEAT; CELLULAR DISTRIBUTION; CIRCULAR DICHROISM; CLEIDOCRANIAL DYSPLASIA; COILED COIL STRUCTURE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; MOLECULAR PATHOLOGY; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CROSS LINKING; PROTEIN DEFECT; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TOXICITY; SACCHAROMYCES CEREVISIAE; SITE DIRECTED MUTAGENESIS; TRINUCLEOTIDE REPEAT; XENOPUS TROPICALIS; CELL LINE; CHEMISTRY; CONFOCAL MICROSCOPY; GENETICS; METABOLISM;

CELL LINE; CIRCULAR DICHROISM; CLEIDOCRANIAL DYSPLASIA; CORE BINDING FACTOR ALPHA 1 SUBUNIT; HUMANS; MICROSCOPY, CONFOCAL; PEPTIDES; PHYLOGENY; PROTEINS;

EID: 84902305180     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu049     Document Type: Article

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