Oligomerization of polyalanine expanded PABPN1 facilitates nuclear protein aggregation that is associated with cell death

Human Molecular Genetics

Volumn 10, Issue 21, 2001, Pages 2341-2351

  Fan, Xueping ^a   Dion, Patrick ^a   Laganiere, Janet ^a   Brais, Bernard ^b   Rouleau, Guy A ^c  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b NOTRE DAME HOSPITAL   (Canada)

^c MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CYTOSINE; GUANINE; NUCLEAR PROTEIN; POLY(A) BINDING PROTEIN NUCLEAR 1; POLYADENYLATED RNA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CELL DEATH; CELL NUCLEUS INCLUSION BODY; CELL STRAIN COS1; CLINICAL OBSERVATION; CONTROLLED STUDY; DYSPHAGIA; EYE MALFORMATION; GENE DELETION; GENE MUTATION; IN VITRO STUDY; MUSCLE WEAKNESS; NONHUMAN; OCULOPHARYNGEAL MUSCULAR DYSTROPHY; OLIGOMERIZATION; ONSET AGE; PREVENTION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DOMAIN; TRINUCLEOTIDE REPEAT;

ANIMALIA;

EID: 0035504113     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/10.21.2341     Document Type: Article

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