To look beyond vasospasm in aneurysmal subarachnoid haemorrhage

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Cossu, Giulia ^a   Messerer, Mahmoud ^a   Oddo, Mauro ^a   Daniel, Roy Thomas ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; ANTITHROMBOCYTIC AGENT; BILIRUBIN; CALCIUM CHANNEL BLOCKING AGENT; CELL ADHESION MOLECULE; CHEMOKINE; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR ANTAGONIST; EPITHELIAL CELL ADHESION MOLECULE; HEMOGLOBIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 6; IRON; MAGNESIUM SULFATE; NEURON SPECIFIC ENOLASE; NITRIC OXIDE; NITRIC OXIDE DONOR; NONSTEROID ANTIINFLAMMATORY AGENT; OXYGEN RADICAL; POTASSIUM; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; VASODILATOR AGENT;

APOPTOSIS; AUTOREGULATION; BLOOD BRAIN BARRIER; BLOOD CLOTTING; BRAIN BLOOD FLOW; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN MICROCIRCULATION; BRAIN VASOSPASM; CALCIUM HOMEOSTASIS; CELL DEATH; CEREBRAL AUTOREGULATION; CEREBROSPINAL FLUID; CLINICAL TRIAL (TOPIC); DELAYED ISCHEMIC NEUROLOGICAL DEFICIT; DEPOLARIZATION; ELECTROLYTE DISTURBANCE; EXCITOTOXICITY; HEMODILUTION; HUMAN; HYPERTENSION; HYPERVOLEMIA; INTRACRANIAL PRESSURE; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PHASE 2 CLINICAL TRIAL (TOPIC); POTASSIUM BLOOD LEVEL; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SIGNAL TRANSDUCTION; SUBARACHNOID HEMORRHAGE; VASOSPASM; MORTALITY; PATHOPHYSIOLOGY; VASOSPASM, INTRACRANIAL;

BRAIN ISCHEMIA; HUMANS; SUBARACHNOID HEMORRHAGE; VASOSPASM, INTRACRANIAL;

EID: 84902266413     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/628597     Document Type: Review

References (158)

1. de Rooij N. K., Linn F. H. H., van der Plas J. A., Algra A., Rinkel G. J. E., Incidence of subarachnoid haemorrhage: a systematic review with emphasis on region, age, gender and time trends. Journal of Neurology, Neurosurgery and Psychiatry 2007 78 12 1365 1372 2-s2.0-34548833530 10.1136/jnnp.2007.117655
2. Venti M., Subarachnoid and intraventricular hemorrhage. Frontiers of Neurology and Neuroscience 2012 30 149 153 2-s2.0-84859194705 10.1159/0003336255
3. Hop J. W., Rinkel G. J., Algra A., van Gijn J., Case-fatality rates and functional outcome after subarachnoid hemorrhage: a systematic review. Stroke 1997 28 3 660 664 10.1161/01.STR.28.3.660
4. Brilstra E. H., Rinkel G. J. E., Algra A., Gijn J., Rebleeding, secondary ischemia, and timing of operation in patients with subarachnoid hemorrhage. Neurology 2000 55 11 1656 1660 2-s2.0-0034642211
5. Ljunggren B., Brandt L., Saveland H., Outcome in 60 consecutive patients treated with early aneurysm operation and intravenous nimodipine. Journal of Neurosurgery 1984 61 5 864 873 2-s2.0-0021717452
6. Kassell N. F., Torner J. C., Haley E. C. Jr., Jane J. A., Adams H. P., Kongable G. L., The International Cooperative Study on the Timing of Aneurysm Surgery. Part 1: overall management results. Journal of Neurosurgery 1990 73 1 18 36 2-s2.0-0025356788
7. Macdonald R. L., Clazosentan: an endothelin receptor antagonist for treatment of vasospasm after subarachnoid hemorrhage. Expert Opinion on Investigational Drugs 2008 17 11 1761 1767 2-s2.0-54949129849 10.1517/13543784.17.11.1761
8. Kramer A., Fletcher J., Do endothelin-receptor antagonists prevent delayed neurological deficits and poor outcomes after aneurysmal subarachnoid hemorrhage?: a meta-analysis. Stroke 2009 40 10 3403 3406 2-s2.0-70349686725 10.1161/STROKEAHA.109.560243
9. Dankbaar J. W., Rijsdijk M., van der Schaaf I. C., Velthuis B. K., Wermer M. J. H., Rinkel G. J. E., Relationship between vasospasm, cerebral perfusion, and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. Neuroradiology 2009 51 12 813 819 2-s2.0-70449527483 10.1007/s00234-009-0575-y
10. Vergouwen M. D. I., Ilodigwe D., MacDonald R. L., Cerebral infarction after subarachnoid hemorrhage contributes to poor outcome by vasospasm-dependent and -independent effects. Stroke 2011 42 4 924 929 2-s2.0-79954911257 10.1161/STROKEAHA.110.597914
11. Bederson J. B., Levy A. L., Ding W. H., Kahn R., DiPerna C. A., Jenkins A. L. III, Vallabhajosyula P., Acute vasoconstriction after subarachnoid hemorrhage. Neurosurgery 1998 42 2 352 362 2-s2.0-0031885565 10.1097/00006123-199802000-00091
12. Kusaka G., Ishikawa M., Nanda A., Granger D. N., Zhang J. H., Signaling pathways for early brain injury after subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism 2004 24 8 916 925 2-s2.0-3843082004
13. Sehba F. A., Pluta R. M., Zhang J. H., Metamorphosis of subarachnoid hemorrhage research: from delayed vasospasm to early brain injury. Molecular Neurobiology 2011 43 1 27 40 2-s2.0-79951557739 10.1007/s12035-010-8155-z
14. Simeone F. A., Ryan K. G., Cotter J. R., Prolonged experimental cerebral vasospasm. Journal of Neurosurgery 1968 29 4 357 366 2-s2.0-0014341431
15. Cahill W. J., Calvert J. H., Zhang J. H., Mechanisms of early brain injury after subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism 2006 26 11 1341 1353 2-s2.0-33750350414 10.1038/sj.jcbfm.9600283
16. Hansen-Schwartz J., Vajkoczy P., Macdonald R. L., Pluta R. M., Zhang J. H., Cerebral vasospasm: looking beyond vasoconstriction. Trends in Pharmacological Sciences 2007 28 6 252 256 2-s2.0-34249333412 10.1016/j.tips.2007.04.002
17. Schwartz A. Y., Masago A., Sehba F. A., Bederson J. B., Experimental models of subarachnoid hemorrhage in the rat: a refinement of the endovascular filament model. Journal of Neuroscience Methods 2000 96 2 161 167 2-s2.0-0034653414 10.1016/S0165-0270(00)00156-4
18. Nornes H., The role of intracranial pressure in the arrest of hemorrhage in patients with ruptured intracranial aneurysm. Journal of Neurosurgery 1973 39 2 226 234 2-s2.0-0015858693
19. Lang E. W., Diehl R. R., Mehdorn H. M., Cerebral autoregulation testing after aneurysmal subarachnoid hemorrhage: the phase relationship between arterial blood pressure and cerebral blood flow velocity. Critical Care Medicine 2001 29 1 158 163 2-s2.0-0035143040
20. Losiniecki A., Zuccarello M., Subarachnoid hemorrhage: effect on cerebral blood flow and cerebral metabolism. Frontiers in Bioscience 2008 13 5 1845 1856 2-s2.0-38449087717 10.2741/2804
21. Berendes E., Walter M., Cullen P., Secretion of brain natriuretic peptide in patients with aneurysmal subarachnoid haemorrhage. The Lancet 1997 349 9047 245 249 10.1016/S0140-6736(96)08093-2
22. Wijdicks E. F. M., Vermeulen M., Haaf J. A. T., Volume depletion and natriuresis in patients with a ruptured intracranial aneurysm. Annals of Neurology 1985 18 2 211 216 2-s2.0-0021830038
23. Harbaugh R. E., Aneurysmal subarachnoid hemorrhage and hyponatremia. Contemporary Neurosurgery 1993 15 1 5 10.1097/00029679-199302000-00001
24. Meguro T., Klett C. P. R., Chen B., Parent A. D., Zhang J. H., Role of calcium channels in oxyhemoglobin-induced apoptosis in endothelial cells. Journal of Neurosurgery 2000 93 4 640 646 2-s2.0-0034433686
25. van den Bergh W. M., Algra A., van der Sprenkel J. W. B., Tulleken C. A. F., Rinkel G. J. E., Hodge C. J. Jr., Awad I. A., Hypomagnesemia after aneurysmal subarachnoid hemorrhage. Neurosurgery 2003 52 2 276 282 2-s2.0-0037309575
26. van den Bergh W. M., Dijkhuizen R. M., Rinkel G. J. E., Potentials of magnesium treatment in subarachnoid haemorrhage. Magnesium Research 2004 17 4 301 313 2-s2.0-12744263413
27. Fukui S., Katoh H., Tsuzuki N., Ishihara S., Otani N., Uozumi Y., Ooigawa H., Toyooka T., Ohnuki A., Miyazawa T., Nawashiro H., Shima K., Gender disparities in serum electrolytes levels after subarachnoid hemorrhage. Journal of Clinical Neuroscience 2004 11 6 606 609 2-s2.0-3142693996 10.1016/j.jocn.2003.02.016
28. Enblad P., Valtysson J., Andersson J., Simultaneous intracerebral microdialysis and positron emission tomography in the detection of ischemia in patients with subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism 1996 16 4 637 644
29. Puyal J., Ginet V., Clarke P. G., Multiple interacting cell death mechanisms in the mediation of excitotoxicity and ischemic brain damage: a challenge for neuroprotection. Progress in Neurobiology 2013 105 24 48 10.1016/j.pneurobio.2013.03.002
30. Owens J., Wyper D. J., Patterson J., First SPET images of glutamate (NMDA) receptor activation in vivo in cerebral ischaemia. Nuclear Medicine Communications 1997 18 2 149 158 10.1097/00006231-199702000-00010
31. Germanò A., Caffo M., Angileri F. F., Arcadi F., Newcomb-Fernandez J., Caruso G., Meli F., Pineda J. A., Lewis S. B., Wang K. K. W., Bramanti P., Costa C., Hayes R. L., NMDA receptor antagonist felbamate reduces behavioral deficits and blood-brain barrier permeability changes after experimental subarachnoid hemorrhage in the rat. Journal of Neurotrauma 2007 24 4 732 744 2-s2.0-34249849556 10.1089/neu.2006.0181
32. Zuccarello M., Lewis A. I., Upputuri S., Farmer J. B., Anderson D. K., Effect of remacemide hydrochloride on subarachnoid hemorrhage-induced vasospasm in rabbits. Journal of Neurotrauma 1994 11 6 691 698 2-s2.0-0028597387
33. Ikonomidou C., Turski L., Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury? The Lancet Neurology 2002 1 6 383 386 2-s2.0-0141676771 10.1016/S1474-4422(02)00164-3
34. Sarrafzadeh A., Huax D., Sakowtz O., Benndorf G., Herzog H., Kuechler I., Unterberg A., Acute focal neurological deficits in aneurysmal subarachnoid hemorrhage: relation of clinical course, CT findings, and metabolite abnormalities monitored with bedside microdialysis. Stroke 2003 34 6 1382 1388 2-s2.0-0037975772 10.1161/01.STR.0000074036.97859.02
35. Bullock R., Zauner A., Woodward J. J., Myseros J., Choi S. C., Ward J. D., Marmarou A., Young H. F., Factors affecting excitatory amino acid release following severe human head injury. Journal of Neurosurgery 1998 89 4 507 518 2-s2.0-0031706636
36. Sehba F. A., Schwartz A. Y., Chereshnev I., Bederson J. B., Acute decrease in cerebral nitric oxide levels after subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism 2000 20 3 604 611 2-s2.0-0034104821
37. Ng W. H., Moochhala S., Yeo T. T., Ong P. L., Ng P. Y., Nitric oxide and subarachnoid hemorrhage: elevated levels in cerebrospinal fluid and their implications. Neurosurgery 2001 49 3 622 627 2-s2.0-0034893797
38. Yatsushige H., Calvert J. W., Cahill J., Zhang J. H., Limited role of inducible nitric oxide synthase in blood-brain barrier function after experimental subarachnoid hemorrhage. Journal of Neurotrauma 2006 23 12 1874 1882 2-s2.0-33845952417 10.1089/neu.2006.23.1874
39. Pluta R. M., Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH. Cerebral Vasospasm 2008 104 139 147 Acta Neurochirurgica Supplementum 10.1007/978-3-211-75718-5-28
40. Hillered L., Vespa P. M., Hovda D. A., Translational neurochemical research in acute human brain injury: the current status and potential future for cerebral microdialysis. Journal of Neurotrauma 2005 22 1 3 41 2-s2.0-12544249525
41. Beckman J. S., Beckman T. W., Chen J., Marshall P. A., Freeman B. A., Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proceedings of the National Academy of Sciences of the United States of America 1990 87 4 1620 1624 2-s2.0-0025189864
42. Thampatty B. P., Sherwood P. R., Gallek M. J., Crago E. A., Ren D., Hricik A. J., Kuo C.-W. J., Klamerus M. M., Alexander S. A., Bender C. M., Hoffman L. A., Horowitz M. B., Kassam A. B., Poloyac S. M., Role of endothelin-1 in human aneurysmal subarachnoid hemorrhage: associations with vasospasm and delayed cerebral ischemia. Neurocritical Care 2011 15 1 19 27 2-s2.0-80052611964 10.1007/s12028-011-9508-9
43. Pluta R. M., Boock R. J., Afshar J. K., Source and cause of endothelin-1 release into cerebrospinal fluid after subarachnoid hemorrhage. Journal of Neurosurgery 1997 87 2 287 293 10.3171/jns.1997.87.2.0287
44. Gruber A., Roessler K., Georgopoulos A., Missbichler A., Bonelli R., Richling B., Evaluation of big endothelin-1 concentrations in serum and ventricular cerebrospinal fluid after early surgical compared with nonsurgical management of ruptured intracranial aneurysms. Neurosurgical Focus 2000 8 5, article e6 2-s2.0-33746889068
45. Mascia L., Fedorko L., Stewart D. J., Mohamed F., TerBrugge K., Ranieri V. M., Wallace M. C., Temporal relationship between endothelin-1 concentrations and cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. Stroke 2001 32 5 1185 1189 2-s2.0-0034839779
46. Afshar J. K. B., Pluta R. M., Boock R. J., Thompson B. G., Oldfield E. H., Effect of intracarotid nitric oxide on primate cerebral vasospasm after subarachnoid hemorrhage. Journal of Neurosurgery 1995 83 1 118 122 2-s2.0-0029063436
47. Gaetani P., Marzatico F., Rodriguez y Baena R., Pacchiarini L., Vigano T., Grignani G., Crivellari M. T., Benzi G., Arachidonic acid metabolism and pathophysiologic aspects of subarachnoid hemorrhage in rats. Stroke 1990 21 2 328 332 2-s2.0-0025181416
48. Kolias A. G., Sen J., Belli A., Pathogenesis of cerebral vasospasm following aneurysmal subarachnoid hemorrhage: putative mechanisms and novel approaches. Journal of Neuroscience Research 2009 87 1 1 11 2-s2.0-63049113042 10.1002/jnr.21823
49. Maeda Y., Hirano K., Nishimura J., Sasaki T., Kanaide H., Endothelial dysfunction and altered bradykinin response due to oxidative stress induced by serum deprivation in the bovine cerebral artery. European Journal of Pharmacology 2004 491 1 53 60 2-s2.0-16544395129 10.1016/j.ejphar.2004.03.019
50. Haley E. C. Jr., Kassell N. F., Apperson-Hansen C., Maile M. H., Alves W. M., A randomized, double-blind, vehicle-controlled trial of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage: a cooperative study in North America. Journal of Neurosurgery 1997 86 3 467 474 10.3171/jns.1997.86.3. 0467
51. Walton J. N., The prognosis and management of subarachnoid haemorrhage. Canadian Medical Association journal 1955 72 3 165 175 2-s2.0-0000690398
52. Spallone A., Acqui M., Pastore F. S., Guidetti B., Relationship between leukocytosis and ischemic complications following aneurysmal subarachnoid hemorrhage. Surgical Neurology 1987 27 3 253 258 2-s2.0-0023138063
53. Dumont A. S., Dumont R. J., Chow M. M., Lin C.-L., Calisaneller T., Ley K. F., Kassell N. F., Lee K. S., Barrow D. L., Macdonald R. L., Hoh B. L., Ogilvy C. S., Lawton M. T., Cerebral vasospasm after subarachnoid hemorrhage: putative role of inflammation. Neurosurgery 2003 53 1 123 135 2-s2.0-0038725119
54. Fountas K. N., Tasiou A., Kapsalaki E. Z., Paterakis K. N., Grigorian A. A., Lee G. P., Robinson J. S. Jr., Serum and cerebrospinal fluid C-reactive protein levels as predictors of vasospasm in aneurysmal subarachnoid hemorrhage. Clinical article. Neurosurgical Focus 2009 26 5, article E22 2-s2.0-67651162192 10.3171/2009.2.FOCUS08311
55. Provencio J. J., Vora N., Subarachnoid hemorrhage and inflammation: bench to bedside and back. Seminars in Neurology 2005 25 4 435 444 2-s2.0-33644844082 10.1055/s-2005-923537
56. Starke R. M., Chalouhi N., Jabbour P. M., Critical role of TNF-alpha in cerebral aneurysm formation and progression to rupture. Journal of Neuroinflammation 2014 11 1, article 77
57. Helmy A., de Simoni M.-G., Guilfoyle M. R., Carpenter K. L. H., Hutchinson P. J., Cytokines and innate inflammation in the pathogenesis of human traumatic brain injury. Progress in Neurobiology 2011 95 3 352 372 2-s2.0-80054112773 10.1016/j.pneurobio.2011.09.003
58. Muroi C., Hugelshofer M., Seule M., Correlation among systemic inflammatory parameter, occurrence of delayed neurological deficits, and outcome after aneurysmal subarachnoid hemorrhage. Neurosurgery 2013 72 3 367 375 10.1227/NEU.0b013e31828048ce
59. Kubo Y., Ogasawara K., Kakino S., Kashimura H., Tomitsuka N., Sugawara A., Ogawa A., Serum inflammatory adhesion molecules and high-sensitivity C-reactive protein correlates with delayed ischemic neurologic deficits after subarachnoid hemorrhage. Surgical Neurology 2008 69 6 592 596 2-s2.0-43449101537 10.1016/j.surneu.2008.02.014
60. Kaynar M. Y., Tanriverdi T., Kafadar A. M., Kacira T., Uzun H., Aydin S., Gumustas K., Dirican A., Kuday C., Detection of soluble intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in both cerebrospinal fluid and serum of patients after aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery 2004 101 6 1030 1036 2-s2.0-16544384377 10.3171/jns.2004.101.6.1030
61. Macdonald R. L., Weir B. K., Cerebral vasospasm and free radicalse. Free Radical Biology and Medicine 1994 16 5 633 643 2-s2.0-0028327284 10.1016/0891-5849(94)90064-7
62. Dietrich H. H., Dacey R. G. Jr., Molecular keys to the problems of cerebral vasospasm. Neurosurgery 2000 46 3 517 530 2-s2.0-0034021806
63. Pluta R. M., Delayed cerebral vasospasm and nitric oxide: review, new hypothesis, and proposed treatment. Pharmacology & Therapeutics 2005 105 1 23 56 2-s2.0-11044230424 10.1016/j.pharmthera.2004.10.002
64. Clark J. F., Sharp F. R., Bilirubin oxidation products (BOXes) and their role in cerebral vasospasm after subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism 2006 26 10 1223 1233 2-s2.0-33748945000 10.1038/sj.jcbfm.9600280
65. Lee J.-Y., Keep R. F., He Y., Sagher O., Hua Y., Xi G., Hemoglobin and iron handling in brain after subarachnoid hemorrhage and the effect of deferoxamine on early brain injury. Journal of Cerebral Blood Flow and Metabolism 2010 30 11 1793 1803 2-s2.0-78049478172 10.1038/jcbfm.2010.137
66. Loftspring M. C., Hansen C., Clark J. F., A novel brain injury mechanism after intracerebral hemorrhage: the interaction between heme products and the immune system. Medical Hypotheses 2010 74 1 63 66 2-s2.0-70450277179 10.1016/j.mehy.2009.08.002
67. Chan P. H., Reactive oxygen radicals in signaling and damage in the ischemic brain. Journal of Cerebral Blood Flow and Metabolism 2001 21 1 2 14 2-s2.0-0035149749
68. Pun P. B. L., Lu J., Moochhala S., Involvement of ROS in BBB dysfunction. Free Radical Research 2009 43 4 348 364 2-s2.0-67650153191 10.1080/ 10715760902751902
69. Sehba F. A., Flores R., Muller A., Friedrich V., Chen J.-F., Britz G. W., Winn H. R., Bederson J. B., Adenosine A 2A receptors in early ischemic vascular injury after subarachnoid hemorrhage: laboratory investigation. Journal of Neurosurgery 2010 113 4 826 834 2-s2.0-77957855305 10.3171/2009.9.JNS09802
70. Sun B.-L., Zheng C.-B., Yang M.-F., Yuan H., Zhang S.-M., Wang L.-X., Dynamic alterations of cerebral pial microcirculation during experimental subarachnoid hemorrhage. Cellular and Molecular Neurobiology 2009 29 2 235 241 2-s2.0-60049093603 10.1007/s10571-008-9316-8
71. Uhl E., Lehmberg J., Steiger H.-J., Messmer K., Dempsey R. J., Stieg P. E., Batjer H. H., Steinmeier R., Schackert G., Solomon R. A., Intraoperative detection of early microvasospasm in patients with subarachnoid hemorrhage by using orthogonal polarization spectral imaging. Neurosurgery 2003 52 6 1307 1317 2-s2.0-0038617711
72. Pennings F. A., Bouma G. J., Ince C., Direct observation of the human cerebral microcirculation during aneurysm surgery reveals increased arteriolar contractility. Stroke 2004 35 6 1284 1288 2-s2.0-2542621531 10.1161/01.STR. 0000126039.91400.cb
73. Sehba F. A., Mostafa G., Knopman J., Friedrich V. Jr., Bederson J. B., Acute alterations in microvascular basal lamina after subarachnoid hemorrhage. Journal of Neurosurgery 2004 101 4 633 640 2-s2.0-7944234917 10.3171/jns.2004.101.4.0633
74. Friedrich V., Flores R., Muller A., Sehba F. A., Luminal platelet aggregates in functional deficits in parenchymal vessels after subarachnoid hemorrhage. Brain Research 2010 1354 179 187 2-s2.0-77956400713 10.1016/j.brainres.2010.07.040
75. Hongo K., Kassel N. F., Nakagomi T., Sasaki T., Tsukahara T., Ogawa H., Vollmer D. G., Lehman R. M., Subarachnoid hemorrhage inhibition of endothelium-derived relaxing factor in rabbit basilar artery. Journal of Neurosurgery 1988 69 2 247 253 2-s2.0-0023759859
76. Hamann G. F., Okada Y., Fitridge R., del Zoppo G. J., Povlishock J. T., Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion. Stroke 1995 26 11 2120 2126 2-s2.0-0028792449
77. Sanchez-Porras R., Robles-Cabrera A., Santos E., Cortical spreading depolarization: a new pathophysiological mechanism in neurological diseases. Medicina Clínica 2014 142 10 457 462 10.1016/j.medcli.2013.05.029
78. Dreier J. P., Windmüller O., Petzold G., Lindauer U., Einhäupl K. M., Dirnagl U., Macdonald R. L., Dempsey R. J., Selman W. R., Mocco J., Connolly E. S. Jr., Ischemia triggered by red blood cell products in the subarachnoid space is inhibited by nimodipine administration or moderate volume expansion/hemodilution in rats. Neurosurgery 2002 51 6 1457 1467 2-s2.0-0036953597 10.1097/00006123-200212000-00017
79. Strong A. J., Anderson P. J., Watts H. R., Virley D. J., Lloyd A., Irving E. A., Nagafuji T., Ninomiya M., Nakamura H., Dunn A. K., Graf R., Peri-infarct depolarizations lead to loss of perfusion in ischaemic gyrencephalic cerebral cortex. Brain 2007 130 part 4 995 1008 2-s2.0-34249658859 10.1093/brain/awl392
80. Sakowitz O. W., Santos E., Nagel A., Clusters of spreading depolarizations are associated with disturbed cerebral metabolism in patients with aneurysmal subarachnoid hemorrhage. Stroke 2013 44 1 220 223 10.1161/STROKEAHA.112.672352
81. Hopwood S. E., Parkin M. C., Bezzina E. L., Boutelle M. G., Strong A. J., Transient changes in cortical glucose and lactate levels associated with peri-infarct depolarisations, studied with rapid-sampling microdialysis. Journal of Cerebral Blood Flow and Metabolism 2005 25 3 391 401 2-s2.0-14644392197 10.1038/sj.jcbfm.9600050
82. Gwag B. J., Canzoniero L. M. T., Sensi S. L., Demaro J. A., Koh J. Y., Goldberg M. P., Jacquin M., Choi D. W., Calcium ionophores can induce either apoptosis or necrosis in cultured cortical neurons. Neuroscience 1999 90 4 1339 1348 2-s2.0-0032903191 10.1016/S0306-4522(98)00508-9
83. Woitzik J., Dreier J. P., Hecht N., Fiss I., Sandow N., Major S., Winkler M., Dahlem Y. A., Manville J., Diepers M., Muench E., Kasuya H., Schmiedek P., Vajkoczy P., Delayed cerebral ischemia and spreading depolarization in absence of angiographic vasospasm after subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism 2012 32 2 203 212 2-s2.0-84856416764 10.1038/jcbfm.2011.169
84. Hartings J. A., Wilson J. A., Look A. C., Full-band electrocorticography of spreading depolarizations in patients with aneurysmal subarachnoid hemorrhage. Cerebral Vasospasm: Neurovascular Events after Subarachnoid Hemorrhage 2013 115 131 141 Acta Neurochirurgica Supplement 10.1007/978-3-7091- 1192-5-27
85. Macdonald R. L., Pluta R. M., Zhang J. H., Cerebral vasospasm after subarachnoid hemorrhage: the emerging revolution. Nature Clinical Practice Neurology 2007 3 5 256 263 2-s2.0-34248524672 10.1038/ncpneuro0490
86. Cunningham R. T., Morrow J. I., Johnston C. F., Buchanan K. D., Serum neurone-specific enolase concentrations in patients with neurological disorders. Clinica Chimica Acta 1994 230 2 117 124 2-s2.0-0028020749 10.1016/0009-8981(94) 90264-X
87. Prunell G. F., Svendgaard N.-A., Alkass K., Mathiesen T., Delayed cell death related to acute cerebral blood flow changes following subarachnoid hemorrhage in the rat brain. Journal of Neurosurgery 2005 102 6 1046 1054 2-s2.0-23144450763 10.3171/jns.2005.102.6.1046
88. Cahill J., Calvert J. W., Solaroglu I., Zhang J. H., Vasospasm and p53-induced apoptosis in an experimental model of subarachnoid hemorrhage. Stroke 2006 37 7 1868 1874 2-s2.0-33745964653 10.1161/01.STR.0000226995.27230.96
89. Broughton B. R. S., Reutens D. C., Sobey C. G., Apoptotic mechanisms after cerebral ischemia. Stroke 2009 40 5 e331 e339 2-s2.0-65549098614 10.1161/STROKEAHA.108.531632
90. Gules I., Satoh M., Nanda A., Zhang J. H., Apoptosis, blood-brain barrier, and subarachnoid hemorrhage. Brain Edema XII 2003 86 483 487 Acta Neurochirurgica Supplements 10.1007/978-3-7091-0651-8-99
91. Zhou C., Yamaguchi M., Kusaka G., Schonholz C., Nanda A., Zhang J. H., Caspase inhibitors prevent endothelial apoptosis and cerebral vasospasm in dog model of experimental subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism 2004 24 4 419 431 2-s2.0-1842533559
92. Zhao H., Ji Z., Tang D., Yan C., Zhao W., Gao C., Role of autophagy in early brain injury after subarachnoid hemorrhage in rats. Molecular Biology Reports 2013 40 2 819 827 10.1007/s11033-012-2120-z
93. Macdonald R. L., Delayed neurological deterioration after subarachnoid haemorrhage. Nature Reviews Neurology 2014 10 1 44 58
94. Dorsch N. W. C., A review of cerebral vasospasm in aneurysmal subarachnoid haemorrhage. Part II: management. Journal of Clinical Neuroscience 1994 1 2 78 92 2-s2.0-0002716459
95. Fergusen S., Macdonald R. L., Predictors of cerebral infarction in patients with aneurysmal subarachnoid hemorrhage. Neurosurgery 2007 60 4 658 667 2-s2.0-34147193048 10.1227/01.NEU.0000255396.23280.31
96. Rothoerl R. D., Ringel F., Molecular mechanisms of cerebral vasospasm following aneurysmal SAH. Neurological Research 2007 29 7 636 642 2-s2.0-36049033130 10.1179/016164107X240224
97. Yanagisawa M., Kurihara H., Kimura S., Tomobe Y., Kobayashi M., Mitsui Y., Goto K., Masaki T., Yazaki Y., A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988 332 6163 411 415 2-s2.0-0023859136
98. Wilkins R. H., Cerebral vasospasm. Critical Reviews in Neurobiology 1990 6 1 51 77 2-s2.0-0025150603
99. Fisher C. M., Kistler J. P., Davis J. M., Relation of cerebral vasospasm to subarachnoid hemorrhage visualized by computerized tomographic scanning. Neurosurgery 1980 6 1 1 9 2-s2.0-0018904811
100. Crowley R. W., Medel R., Dumont A. S., Ilodigwe D., Kassell N. F., Mayer S. A., Ruefenacht D., Schmiedek P., Weidauer S., Pasqualin A., MacDonald R. L., Angiographic vasospasm is strongly correlated with cerebral infarction after subarachnoid hemorrhage. Stroke 2011 42 4 919 923 2-s2.0-79954569223 10.1161/STROKEAHA.110.597005
101. Weidauer S., Lanfermann H., Raabe A., Zanella F., Seifert V., Beck J., Impairment of cerebral perfusion and infarct patterns attributable to vasospasm after aneurysmal subarachnoid hemorrhage: a prospective MRI and DSA Study. Stroke 2007 38 6 1831 1836 2-s2.0-34249812959 10.1161/STROKEAHA.106.477976
102. Povlsen G. K., Johansson S. E., Larsen C. C., Samraj A. K., Edvinsson L., Early events triggering delayed vasoconstrictor receptor upregulation and cerebral ischemia after subarachnoid hemorrhage. BMC Neuroscience 2013 14, article 34 10.1186/1471-2202-14-34
103. Paulson O. B., Strandgaard S., Edvinsson L., Cerebral autoregulation. Cerebrovascular and Brain Metabolism Reviews 1990 2 2 161 192 2-s2.0-0025437969
104. Dorsch N., A clinical review of cerebral vasospasm and delayed ischaemia following aneurysm rupture. Early Brain Injury or Cerebral Vasospasm 2011 110-111 5 6 Acta Neurochirurgica Supplements 10.1007/978-3-7091-0353-1-1
105. Jaeger M., Jeanneret B., Schaeren S., Spontaneous spinal epidural haematoma during Factor Xa inhibitor treatment (Rivaroxaban). European Spine Journal 2012 21 supplement 4 S433 S435 10.1007/s00586-011-2003-3
106. Jaeger M., Schuhmann M. U., Soehle M., Nagel C., Meixensberger J., Continuous monitoring of cerebrovascular autoregulation after subarachnoid hemorrhage by brain tissue oxygen pressure reactivity and its relation to delayed cerebral infarction. Stroke 2007 38 3 981 986 2-s2.0-33947497488 10.1161/01.STR.0000257964.65743.99
107. Dreier J. P., Major S., Manning A., Woitzik J., Drenckhahn C., Steinbrink J., Tolias C., Oliveira-Ferreira A. I., Fabricius M., Hartings J. A., Vajkoczy P., Lauritzen M., Dirnagl U., Bohner G., Strong A. J., Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage. Brain 2009 132 part 7 1866 1881 2-s2.0-67650089668 10.1093/brain/awp102
108. Hadeishi H., Mizuno M., Suzuki A., Yasui N., Hyperdynamic therapy for cerebral vasospasm. Neurologia Medico-Chirurgica 1990 30 5 317 323 2-s2.0-0025003231
109. Finn S. S., Stephensen S. A., Miller C. A., Observations on the perioperative management of aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery 1986 65 1 48 62 2-s2.0-0022444185
110. Raabe A., Beck J., Keller M., Vatter H., Zimmermann M., Seifert V., Relative importance of hypertension compared with hypervolemia for increasing cerebral oxygenation in patients with cerebral vasospasm after subarachnoid hemorrhage. Journal of Neurosurgery 2005 103 6 974 981 2-s2.0-32044460643 10.3171/jns.2005.103.6.0974
111. Muench E., Horn P., Bauhuf C., Roth H., Philipps M., Hermann P., Quintel M., Schmiedek P., Vajkoczy P., Effects of hypervolemia and hypertension on regional cerebral blood flow, intracranial pressure, and brain tissue oxygenation after subarachnoid hemorrhage. Critical Care Medicine 2007 35 8 1844 1852 2-s2.0-34547681749 10.1097/01.CCM.0000275392.08410.DD
112. Diringer M. N., Bleck T. P., Hemphill J. C. III, Menon D., Shutter L., Vespa P., Bruder N., Connolly E. S. Jr., Citerio G., Gress D., Hänggi D., Hoh B. L., Lanzino G., Le Roux P., Rabinstein A., Schmutzhard E., Stocchetti N., Suarez J. I., Treggiari M., Tseng M.-Y., Vergouwen M. D. I., Wolf S., Zipfel G., Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocritical Care 2011 15 2 211 240 2-s2.0-80053131240 10.1007/s12028-011-9605-9
113. Bederson J. B., Connolly Jr.E.S., Batjer H.H., Dacey R.G., Dion J.E., Diringer M.N., Duldner Jr.J.E., Harbaugh R.E., Patel A.B., Rosenwasser R.H., Guidelines for the management of aneurysmal subarachnoid hemorrhage: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke 2009 40 3 994 1025 2-s2.0-62449310759 10.1161/STROKEAHA.108.191395
114. Mees S. M. D., Rinkel G. J., Feigin V. L., Algra A., van den Bergh W. M., Vermeulen M., van Gijn J., Calcium antagonists for aneurysmal subarachnoid haemorrhage. Cochrane Database of Systematic Reviews 2007 3 CD000277 2-s2.0-35348846464 10.1002/14651858.CD000277.pub3
115. Muroi C., Burkhardt J. K., Hugelshofer M., Seule M., Mishima K., Keller E., Magnesium and the inflammatory response: potential pathophysiological implications in the management of patients with aneurysmal subarachnoid hemorrhage? Magnesium Research 2012 25 2 64 71
116. MacDonald R. L., Curry D. J., Aihara Y., Zhang Z.-D., Jahromi B. S., Yassari R., Magnesium and experimental vasospasm. Journal of Neurosurgery 2004 100 1 106 110 2-s2.0-0346993067
117. Veyna R. S., Seyfried D., Burke D. G., Zimmerman C., Mlynarek M., Nichols V., Marrocco A., Thomas A. J., Mitsias P. D., Malik G. M., Magnesium sulfate therapy after aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery 2002 96 3 510 514 2-s2.0-0036125842
118. Wong G. K. C., Poon W. S., Chan M. T. V., Boet R., Gin T., Ng S. C. P., Zee B. C. Y., Intravenous magnesium sulphate for aneurysmal subarachnoid hemorrhage (IMASH): a randomized, double-blinded, placebo-controlled, multicenter phase III trial. Stroke 2010 41 5 921 926 2-s2.0-77951766835 10.1161/STROKEAHA.109.571125
119. MacDonald R. L., Kassell N. F., Mayer S., Ruefenacht D., Schmiedek P., Weidauer S., Frey A., Roux S., Pasqualin A., Clazosentan to overcome neurological ischemia and infarction occurring after subarachnoid hemorrhage (CONSCIOUS-1): randomized, double-blind, placebo-controlled phase 2 dose-finding trial. Stroke 2008 39 11 3015 3021 2-s2.0-55749089548 10.1161/STROKEAHA.108. 519942
120. Macdonald R. L., Higashida R. T., Keller E., Mayer S. A., Molyneux A., Raabe A., Vajkoczy P., Wanke I., Bach D., Frey A., Marr A., Roux S., Kassell N., Clazosentan, an endothelin receptor antagonist, in patients with aneurysmal subarachnoid haemorrhage undergoing surgical clipping: a randomised, double-blind, placebo-controlled phase 3 trial (CONSCIOUS-2). The Lancet Neurology 2011 10 7 618 625 2-s2.0-79958803259 10.1016/S1474-4422(11)70108-9
121. Arakawa Y., Kikuta K.-I., Hojo M., Goto Y., Ishii A., Yamagata S., Milrinone for the treatment of cerebral vasospasm after subarachnoid hemorrhage: report of seven cases. Neurosurgery 2001 48 4 723 730 2-s2.0-0035063438
122. Chanani N. K., Cowan D. B., Takeuchi K., Poutias D. N., Garcia L. M., del Nido P. J., McGowan F. X. Jr., Differential effects of amrinone and milrinone upon myocardial inflammatory signaling. Circulation 2002 106 12, supplement 1 I284 I289 2-s2.0-0037167645
123. Ding D., Starke R. M., Dumont A. S., Therapeutic implications of estrogen for cerebral vasospasm and delayed cerebral ischemia induced by aneurysmal subarachnoid hemorrhage. BioMed Research International 2014 2014 9 727428 10.1155/2014/727428
124. Lin C.-L., Shih H.-C., Dumont A. S., Kassell N. F., Lieu A.-S., Su Y.-F., Hwong S.-L., Hsu C., The effect of 17 β -estradiol in attenuating experimental subarachnoid hemorrhage-induced cerebral vasospasm. Journal of Neurosurgery 2006 104 2 298 304 2-s2.0-33644529090
125. Srivastava S., Weitzmann M. N., Cenci S., Ross F. P., Adler S., Pacifici R., Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD. Journal of Clinical Investigation 1999 104 4 503 513 2-s2.0-0032694582
126. Pluta R. M., Dejam A., Grimes G., Gladwin M. T., Oldfield E. H., Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage. Journal of the American Medical Association 2005 293 12 1477 1484 2-s2.0-15044344420 10.1001/jama.293.12.1477
127. Hino A., Tokuyama Y., Weir B., Changes in endothelial nitric oxide synthase mRNA during vasospasm after subarachnoid hemorrhage in monkeys. Neurosurgery 1996 39 3 562 568
128. Gaetani P., Marzatico F., Renault B., Fulle I., Lombardi D., Ferlenga P., Rodriguez y Baena R., High-dose methylprednisolone and "ex vivo"
129. Gomis P., Graftieaux J. P., Sercombe R., Hettler D., Scherpereel B., Rousseaux P., Randomized, double-blind, placebo-controlled, pilot trial of high-dose methylprednisolone in aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery 2010 112 3 681 688 2-s2.0-77749254703 10.3171/2009.4.JNS081377
130. Zhang S., Wang L., Liu M., Wu B., Tirilazad for aneurysmal subarachnoid haemorrhage. Cochrane Database of Systematic Reviews 2010 2 10.1002/14651858. CD006778.pub2 CD006778 2-s2.0-77950928661
131. Munakata A., Ohkuma H., Nakano T., Shimamura N., Asano K., Naraoka M., Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage. Neurosurgery 2009 64 3 423 429 2-s2.0-62849108201 10.1227/01.NEU.0000338067.83059.EB
132. Zhang X. S., Zhang X., Zhou M. L., Amelioration of oxidative stress and protection against early brain injury by astaxanthin after experimental subarachnoid hemorrhage. Journal of Neurosurgery 2014 10.3171/2014.2.JNS13730
133. 2+ entry and mitogen-activated protein kinase signaling pathway. Journal of Agricultural and Food Chemistry 2010 58 14 8271 8278 2-s2.0-77954886020 10.1021/jf101689t
134. Lee S.-J., Bai S.-K., Lee K.-S., Namkoong S., Na H.-J., Ha K.-S., Han J.-A., Yim S.-V., Chang K., Kwon Y.-G., Lee S. K., Kim Y.-M., Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I B kinase-dependent NF- B activation. Molecules and Cells 2003 16 1 97 105 2-s2.0-3042742915
135. Khan S. K., Malinski T., Mason R. P., Kubant R., Jacob R. F., Fujioka K., Denstaedt S. J., King T. J., Jackson H. L., Hieber A. D., Lockwood S. F., Goodin T. H., Pashkow F. J., Bodary P. F., Novel astaxanthin prodrug (CDX-085) attenuates thrombosis in a mouse model. Thrombosis Research 2010 126 4 299 305 2-s2.0-77957126045 10.1016/j.thromres.2010.07.003
136. Fassett R. G., Coombes J. S., Astaxanthin, oxidative stress, inflammation and cardiovascular disease. Future Cardiology 2009 5 4 333 342 2-s2.0-69749120073 10.2217/fca.09.19
137. Muroi C., Hugelshofer M., Seule M., Keller E., The impact of nonsteroidal anti-inflammatory drugs on inflammatory response after aneurysmal subarachnoid hemorrhage. Neurocritical Care 2014 20 2 240 246 10.1007/s12028-013-9930-2
138. Juvela S., Aspirin and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery 1995 82 6 945 952 2-s2.0-0029005396
139. Iso H., Hennekens C. H., Stampfer M. J., Rexrode K. M., Colditz G. A., Speizer F. E., Willett W. C., Manson J. E., Prospective study of aspirin use and risk of stroke in women. Stroke 1999 30 9 1764 1771 2-s2.0-0032825255
140. Muroi C., Fujioka M., Mishima K., Effect of ADAMTS-13 on cerebrovascular microthrombosis and neuronal injury after experimental subarachnoid hemorrhage. Journal of Thrombosis and Haemostasis 2014 12 4 505 514 10.1111/jth.12511
141. Laufs U., Fata V. L., Liao J. K., Inhibition of 3-hydroxy-3- methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase. The Journal of Biological Chemistry 1997 272 50 31725 31729
142. O'Driscoll G., Green D., Taylor R. R., Simvastatin, an HMG-coenzyme A reductase inhibitor, improves endothelial function within 1 month. Circulation 1997 95 5 1126 1131 10.1161/01.CIR.95.5.1126
143. Sehba F. A., Friedrich V. Jr., Makonnen G., Bederson J. B., Acute cerebral vascular injury after subarachnoid hemorrhage and its prevention by administration of a nitric oxide donor. Journal of Neurosurgery 2007 106 2 321 329 2-s2.0-33846844806 10.3171/jns.2007.106.2.321
144. Tseng M.-Y., Czosnyka M., Richards H., Pickard J. D., Kirkpatrick P. J., Effects of acute treatment with pravastatin on cerebral vasospasm, autoregulation, and delayed ischemic deficits after aneurysmal subarachnoid hemorrhage: a phase II randomized placebo-controlled trial. Stroke 2005 36 8 1627 1632 2-s2.0-23244432198 10.1161/01.STR.0000176743.67564.5d
145. Tseng M.-Y., Hutchinson P. J., Czosnyka M., Richards H., Pickard J. D., Kirkpatrick P. J., Effects of acute pravastatin treatment on intensity of rescue therapy, length of inpatient stay, and 6-month outcome in patients after aneurysmal subarachnoid hemorrhage. Stroke 2007 38 5 1545 1550 2-s2.0-34247622293 10.1161/STROKEAHA.106.475905
146. Tapia-Pérez J. H., Sanchez-Aguilar M., Schneider T., The role of statins in neurosurgery. Neurosurgical Review 2010 33 3 259 270 2-s2.0-77956465545 10.1007/s10143-010-0259-4
147. Kramer A. H., Fletcher J. J., Statins in the management of patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis. Neurocritical Care 2010 12 2 285 296 2-s2.0-77953613257 10.1007/s12028-009-9306- 9
148. Nolan C. P., Macdonald R. L., Can angiographic vasospasm be used as a surrogate marker in evaluating therapeutic interventions for cerebral vasospasm? Neurosurgical Focus 2006 21 3, article E1 2-s2.0-33750587570
149. Ecker A., Riemenschneider P. A., Arteriographic demonstration of spasm of the intracranial arteries, with special reference to saccular arterial aneurysms. Journal of Neurosurgery 1951 8 6 660 667 2-s2.0-0001337612
150. Alaraj A., Charbel F. T., Amin-Hanjani S., Peri-operative measures for treatment and prevention of cerebral vasospasm following subarachnoid hemorrhage. Neurological Research 2009 31 6 651 659 2-s2.0-68149183517 10.1179/174313209X382395
151. Liebeskind D. S., Collateral circulation. Stroke 2003 34 9 2279 2284 2-s2.0-0042919302 10.1161/01.STR.0000086465.41263.06
152. Naidech A. M., Drescher J., Tamul P., Shaibani A., Batjer H. H., Alberts M. J., Acute physiological derangement is associated with early radiographic cerebral infarction after subarachnoid haemorrhage. Journal of Neurology, Neurosurgery and Psychiatry 2006 77 12 1340 1344 2-s2.0-33845222687 10.1136/jnnp.2006.089748
153. Suzuki S., Kimura M., Souma M., Ohkima H., Iwabuchi T., Shimiz u T., Cerebral microthrombosis in symptomatic cerebral vasospasm-a quantitative histological study in autopsy cases. Neurologia Medico-Chirurgica 1990 30 5 309 316 2-s2.0-0025113021
154. Nau R., Haase S., Bunkowski S., Brück W., Neuronal apoptosis in the denate gyrus in humans with subarachnoid hemorrage and cerebral hypoxia. Brain Pathology 2002 12 3 329 336 2-s2.0-0036019160
155. Diringer M. N., Heffez D. S., Monsein L., Kirsch J. R., Hanley D. F., Traystman R. J., Cerebrovascular CO2 reactivity during delayed vasospasm in a canine model of subarachnoid hemorrhage. Stroke 1991 22 3 367 372 2-s2.0-0025924557
156. Leng L. Z., Fink M. E., Iadecola C., Spreading depolarization: a possible new culprit in the delayed cerebral ischemia of subarachnoid hemorrhage. Archives of Neurology 2011 68 1 31 36 2-s2.0-78651280074 10.1001/archneurol. 2010.226
157. Messerer M., Daniel R. T., Oddo M., Neuromonitoring after major neurosurgical procedures. Minerva Anestesiologica 2012 78 7 810 822
158. Tisdall M. M., Smith M., Cerebral microdialysis: research technique or clinical tool. British Journal of Anaesthesia 2006 97 1 18 25 2-s2.0-33745684731 10.1093/bja/ael109