Delayed cerebral ischemia and spreading depolarization in absence of angiographic vasospasm after subarachnoid hemorrhage

Journal of Cerebral Blood Flow and Metabolism

Volumn 32, Issue 2, 2012, Pages 203-212

  Woitzik, Johannes ^a,b   Dreier, Jens P ^a   Hecht, Nils ^a   Fiss, Ingo ^a   Sandow, Nora ^a   Major, Sebastian ^a   Winkler, Maren ^a   Dahlem, Yuliya A ^a   Manville, Jerome ^b   Diepers, Michael ^c   Muench, Elke ^c   Kasuya, Hidetoshi ^d   Schmiedek, Peter ^b   Vajkoczy, Peter ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c Universitätsmedizin Mannheim ^*  (Germany)

^d TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

microcirculation; neurovascular coupling; spreading depression; subarachnoid hemorrhage; vasospasm

Indexed keywords

NICARDIPINE;

ADULT; AGED; ANEURYSM CLIP; ARTICLE; BRAIN ISCHEMIA; CLINICAL ARTICLE; DEPOLARIZATION; DIGITAL SUBTRACTION ANGIOGRAPHY; DRUG DELIVERY SYSTEM; DRUG RELEASE; ELECTRODE; FEMALE; HUMAN; IMPLANT; MALE; PRIORITY JOURNAL; SUBARACHNOID HEMORRHAGE; VASOSPASM;

ADULT; AGED; ANGIOGRAPHY, DIGITAL SUBTRACTION; ANTIHYPERTENSIVE AGENTS; BRAIN; BRAIN ISCHEMIA; CORTICAL SPREADING DEPRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; NICARDIPINE; PROSPECTIVE STUDIES; PROSTHESES AND IMPLANTS; SUBARACHNOID HEMORRHAGE; VASOSPASM, INTRACRANIAL;

EID: 84856416764     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2011.169     Document Type: Article

References (40)

1. Abdelmoneim SS, Wijdicks EF, Lee VH, Daugherty WP, Bernier M, Oh JK, Pellikka PA, Mulvagh SL (2009) Real-time myocardial perfusion contrast echocardiography and regional wall motion abnormalities after aneurysmal subarachnoid hemorrhage. Clinical article. J Neurosurg 111:1023-8
2. Adams Jr HP, del Zoppo G, Alberts MJ, Bhatt DL, Brass L, Furlan A, Grubb RL, Higashida RT, Jauch EC, Kidwell C, Lyden PD, Morgenstern LB, Qureshi AI, Rosenwasser RH, Scott PA, Wijdicks EF (2007) Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Circulation 115:478-534
3. Barth M, Capelle HH, Weidauer S, Weiss C, Munch E, Thome C, Luecke T, Schmiedek P, Kasuya H, Vajkoczy P (2007) Effect of nicardipine prolonged-release implants on cerebral vasospasm and clinical outcome after severe aneurysmal subarachnoid hemorrhage: a prospective, randomized, double-blind phase IIa study. Stroke 38:330-6 (Pubitemid 46188258)
4. Barth M, Woitzik J, Weiss C, Muench E, Diepers M, Schmiedek P, Kasuya H, Vajkoczy P (2010) Correlation of clinical outcome with pressure-, oxygen-, and flow-related indices of cerebrovascular reactivity in patients following aneurysmal SAH. Neurocrit Care 12:234-43
5. Bosche B, Graf R, Ernestus RI, Dohmen C, Reithmeier T, Brinker G, Strong AJ, Dreier JP, Woitzik J (2010) Recurrent spreading depolarizations after subarachnoid hemorrhage decreases oxygen availability in human cerebral cortex. Ann Neurol 67:607-17
6. Brouwers PJ, Wijdicks EF, Van Gijn J (1992) Infarction after aneurysm rupture does not depend on distribution or clearance rate of blood. Stroke 23:374-9
7. Burns JD, Rabinstein AA, Cloft H, Lanzino G, Daniels DJ, Wijdicks EF (2009a) Minimally conscious state after ruptured giant basilar aneurysm. Arch Neurol 66:786-8
8. Burns JD, Schiefer TK, Wijdicks EF (2009b) Large and small: a telltale sign of acute pontomesencephalic injury. Neurology 72:1707
9. Drake CG (1988) Report of World Federation of Neurological Surgeons Committee on a Universal Subarachnoid Hemorrhage Grading scale. J Neurosurg 68:985-6
10. Dreier JP, Ebert N, Priller J, Megow D, Lindauer U, Klee R, Reuter U, Imai Y, Einhaupl KM, Victorov I, Dirnagl U (2000) Products of hemolysis in the subarachnoid space inducing spreading ischemia in the cortex and focal necrosis in rats: a model for delayed ischemic neurological deficits after subarachnoid hemorrhage? J Neurosurg 93:658-66 (Pubitemid 32799301)
11. Dreier JP, Korner K, Ebert N, Gorner A, Rubin I, Back T, Lindauer U, Wolf T, Villringer A, Einhaupl KM, Lauritzen M, Dirnagl U (1998) Nitric oxide scavenging by hemoglobin or nitric oxide synthase inhibition by N-nitro-L-arginine induces cortical spreading ischemia when K+ is increased in the subarachnoid space. J Cereb Blood Flow Metab 18:978-90 (Pubitemid 28427865)
12. Dreier JP, Major S, Manning A, Woitzik J, Drenckhahn C, Steinbrink J, Tolias C, Oliveira-Ferreira AI, Fabricius M, Hartings JA, Vajkoczy P, Lauritzen M, Dirnagl U, Bohner G, Strong AJ (2009) Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage. Brain 132:1866-81
13. Dreier JP, Windmuller O, Petzold G, Lindauer U, Einhaupl KM, Dirnagl U (2002) Ischemia triggered by red blood cell products in the subarachnoid space is inhibited by nimodipine administration or moderate volume expansion/hemodilution in rats. Neurosurgery 51:1457-65
14. Dreier JP, Woitzik J, Fabricius M, Bhatia R, Major S, Drenckhahn C, Lehmann TN, Sarrafzadeh A, Willumsen L, Hartings JA, Sakowitz OW, Seemann JH, Thieme A, Lauritzen M, Strong AJ (2006) Delayed ischaemic neurological deficits after subarachnoid haemorrhage are associated with clusters of spreading depolarizations. Brain 129:3224-37 (Pubitemid 44871438)
15. Dupont SA, Wijdicks EF, Manno EM, Lanzino G, Brown Jr RD, Rabinstein AA (2009) Timing of computed tomography and prediction of vasospasm after aneurysmal subarachnoid hemorrhage. Neurocrit Care 11:71-5
16. Fabricius M, Fuhr S, Bhatia R, Boutelle M, Hashemi P, Strong AJ, Lauritzen M (2006) Cortical spreading depression and peri-infarct depolarization in acutely injured human cerebral cortex. Brain 129:778-90 (Pubitemid 43278239)
17. Haley Jr EC, Kassell NF, Apperson-Hansen C, Maile MH, Alves WM (1997) A randomized, double-blind, vehiclecontrolled trial of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage: a cooperative study in North America. J Neurosurg 86:467-74 (Pubitemid 27097093)
18. Jaeger M, Schuhmann MU, Soehle M, Nagel C, Meixensberger J (2007) Continuous monitoring of cerebrovascular autoregulation after subarachnoid hemorrhage by brain tissue oxygen pressure reactivity and its relation to delayed cerebral infarction. Stroke 38:981-6 (Pubitemid 46568462)
19. Kiening KL, Unterberg AW, Bardt TF, Schneider GH, Lanksch WR (1996) Monitoring of cerebral oxygenation in patients with severe head injuries: brain tissue PO2 versus jugular vein oxygen saturation. J Neurosurg 85:751-7 (Pubitemid 26362136)
20. Kistler JP, Crowell RM, Davis KR, Heros R, Ojemann RG, Zervas T, Fisher CM (1983) The relation of cerebral vasospasm to the extent and location of subarachnoid blood visualized by CT scan: a prospective study. Neurology 33:424-36 (Pubitemid 13165320)
21. Lanzino G, Kassell NF (1999) Double-blind, randomized, vehicle-controlled study of high-dose tirilazad mesylate in women with aneurysmal subarachnoid hemorrhage. Part II. A cooperative study in North America. J Neurosurg 90:1018-24 (Pubitemid 29241167)
22. Lanzino G, Kassell NF, Dorsch NW, Pasqualin A, Brandt L, Schmiedek P, Truskowski LL, Alves WM (1999) Doubleblind, randomized, vehicle-controlled study of highdose tirilazad mesylate in women with aneurysmal subarachnoid hemorrhage. Part I. A cooperative study in Europe, Australia, New Zealand, and South Africa. J Neurosurg 90:1011-7 (Pubitemid 29241166)
23. Leão AA (1947) Further observations on the spreading depression of activity in the cerebral cortex. J Neurophysiol 10:409-14
24. Macdonald RL, Kassell NF, Mayer S, Ruefenacht D, Schmiedek P, Weidauer S, Frey A, Roux S, Pasqualin A (2008) Clazosentan to overcome neurological ischemia and infarction occurring after subarachnoid hemorrhage (CONSCIOUS-1): randomized, double-blind, placebo-controlled phase 2 dose-finding trial. Stroke 39:3015-21
25. Macdonald RL, Weir BK (1991) A review of hemoglobin and the pathogenesis of cerebral vasospasm. Stroke 22:971-82
26. Mateen FJ, Nasser M, Spencer BR, Freeman WD, Shuaib A, Demaerschalk BM, Wijdicks EF (2009) Outcomes of intravenous tissue plasminogen activator for acute ischemic stroke in patients aged 90 years or older. Mayo Clin Proc 84:334-8
27. Minhas PS, Menon DK, Smielewski P, Czosnyka M, Kirkpatrick PJ, Clark JC, Pickard JD (2003) Positron emission tomographic cerebral perfusion disturbances and transcranial Doppler findings among patients with neurological deterioration after subarachnoid hemorrhage. Neurosurgery 52:1017-22
28. Neil-Dwyer G, Lang DA, Doshi B, Gerber CJ, Smith PW (1994) Delayed cerebral ischaemia: the pathological substrate. Acta Neurochir (Wien) 131:137-45 (Pubitemid 24348142)
29. Pluta RM, Hansen-Schwartz J, Dreier J, Vajkoczy P, Macdonald RL, Nishizawa S, Kasuya H, Wellman G, Keller E, Zauner A, Dorsch N, Clark J, Ono S, Kiris T, Leroux P, Zhang JH (2009) Cerebral vasospasm following subarachnoid hemorrhage: time for a new world of thought. Neurol Res 31:151-8
30. Rabinstein AA, Weigand S, Atkinson JL, Wijdicks EF (2005) Patterns of cerebral infarction in aneurysmal subarachnoid hemorrhage. Stroke 36:992-7 (Pubitemid 40629290)
31. Rabinstein AA, Wijdicks EF (2009) Fatal brain swelling due to superior vena cava syndrome. Neurocrit Care 10:91-2
32. Stead LG, Wijdicks EF, Bhagra A, Kashyap R, Bellolio MF, Nash DL, Enduri S, Schears R, William B (2009) Validation of a new coma scale, the FOUR score, in the emergency department. Neurocrit Care 10:50-4
33. Stein SC, Browne KD, Chen XH, Smith DH, Graham DI (2006) Thromboembolism and delayed cerebral ischemia after subarachnoid hemorrhage: an autopsy study. Neurosurgery 59:781-7 (Pubitemid 44579595)
34. Strong AJ, Fabricius M, Boutelle MG, Hibbins SJ, Hopwood SE, Jones R, Parkin MC, Lauritzen M (2002) Spreading and synchronous depressions of cortical activity in acutely injured human brain. Stroke 33:2738-43 (Pubitemid 35462836)
35. Sukhotinsky I, Yaseen MA, Sakadzic S, Ruvinskaya S, Sims JR, Boas DA, Moskowitz MA, Ayata C (2010) Perfusion pressure-dependent recovery of cortical spreading depression is independent of tissue oxygenation over a wide physiologic range. J Cereb Blood Flow Metab 30:1168-77
36. Unterberg AW, Sakowitz OW, Sarrafzadeh AS, Benndorf G, Lanksch WR (2001) Role of bedside microdialysis in the diagnosis of cerebral vasospasm following aneurysmal subarachnoid hemorrhage. J Neurosurg 94:740-9 (Pubitemid 32799622)
37. Weidauer S, Vatter H, Beck J, Raabe A, Lanfermann H, Seifert V, Zanella F (2008) Focal laminar cortical infarcts following aneurysmal subarachnoid haemorrhage. Neuroradiology 50:1-8
38. Wijdicks EF, Cloft HJ (2009) Is prediction of outcome with magnetic resonance imaging in postresuscitation coma achievable and accurate? Ann Neurol 65:364-6
39. Zubkov AY, Rabinstein AA, Manno EM, Wijdicks EF (2008) Prolonged refractory status epilepticus related to thrombotic thrombocytopenic purpura. Neurocrit Care 9:361-5
40. Zubkov AY, Wijdicks EF (2009) Deep venous thrombosis prophylaxis in cerebral hemorrhage. Rev Neurol Dis 6:21-5