Conditional ablation of astroglial CCL2 suppresses CNS accumulation of M1 macrophages and preserves axons in Mice with MOG peptide EAE

Journal of Neuroscience

Volumn 34, Issue 24, 2014, Pages 8175-8185

  Moreno, Monica ^a   Bannerman, Peter ^a   Ma, Joyce ^a   Guo, Fuzheng ^a   Miers, Laird ^a   Soulika, Athena M ^a   Pleasure, David ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Astroglia; Axonopathy; Chemokine; EAE; Macrophage; Myelin

Indexed keywords

INTERLEUKIN 1; MESSENGER RNA; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; CELL MIGRATION; CENTRAL NERVOUS SYSTEM FUNCTION; CONTROLLED STUDY; DEMYELINATION; ENCEPHALITIS; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEMALE; FLOW CYTOMETRY; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MOUSE; MULTIPLE SCLEROSIS; NEUROPATHY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

ASTROGLIA; AXONOPATHY; CHEMOKINE; EAE; MACROPHAGE; MYELIN;

ANALYSIS OF VARIANCE; ANIMALS; ASTROCYTES; AXONS; BACTERIAL PROTEINS; CENTRAL NERVOUS SYSTEM; CHEMOKINE CCL2; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FLOW CYTOMETRY; GLIAL FIBRILLARY ACIDIC PROTEIN; LUMINESCENT PROTEINS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, TRANSMISSION; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; PEPTIDE FRAGMENTS; PROTEINS;

EID: 84902181363     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1137-14.2014     Document Type: Article

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