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Volumn 127, Issue 5, 2004, Pages 1009-1018

Axonal loss in multiple sclerosis: A pathological survey of the corticospinal and sensory tracts

Author keywords

Axonal loss; Multiple sclerosis; Neuropathology

Indexed keywords

ADULT; AGED; AUTOPSY; AXONAL INJURY; CELL DENSITY; CELL LOSS; CELL POPULATION; CERVICAL SPINAL CORD; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HUMAN; HUMAN TISSUE; LUMBAR SPINAL CORD; MAJOR CLINICAL STUDY; MALE; MEDULLA OBLONGATA; MULTIPLE SCLEROSIS; NERVE TRACT; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PYRAMIDAL TRACT; QUANTITATIVE ANALYSIS; REVIEW; SENSORY NERVE;

EID: 2442555263     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/awh118     Document Type: Review
Times cited : (221)

References (27)
  • 1
    • 0033511936 scopus 로고    scopus 로고
    • Axonal pathology in myelin disorders
    • Bjartmar C, Yin X, Trapp BD. Axonal pathology in myelin disorders. J Neurocytol 1999; 28: 383-95.
    • (1999) J Neurocytol , vol.28 , pp. 383-395
    • Bjartmar, C.1    Yin, X.2    Trapp, B.D.3
  • 2
    • 0033663894 scopus 로고    scopus 로고
    • Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients
    • Bjartmar C, Kidd G, Mork S, Rudick R, Trapp BD. Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients. Ann Neurol 2000; 48: 793-901.
    • (2000) Ann Neurol , vol.48 , pp. 793-901
    • Bjartmar, C.1    Kidd, G.2    Mork, S.3    Rudick, R.4    Trapp, B.D.5
  • 3
    • 0035833965 scopus 로고    scopus 로고
    • Axonal loss in normal-appearing white matter in a patient with acute MS
    • Bjartmar C, Kinkel RP, Kidd G, Rudick RA, Trapp BD. Axonal loss in normal-appearing white matter in a patient with acute MS. Neurology 2001; 57: 1248-52.
    • (2001) Neurology , vol.57 , pp. 1248-1252
    • Bjartmar, C.1    Kinkel, R.P.2    Kidd, G.3    Rudick, R.A.4    Trapp, B.D.5
  • 4
    • 0000361150 scopus 로고
    • Histologie de la sclerose en plaques
    • Charcot M. Histologie de la sclerose en plaques. Gaz Hop (Paris) 1868; 141: 554-8.
    • (1868) Gaz Hop (Paris) , vol.141 , pp. 554-558
    • Charcot, M.1
  • 5
    • 0029565567 scopus 로고
    • Persistent functional deficit in multiple sclerosis and autosomal dominant cerebellar ataxia is associated with axon loss
    • Davie CA, Barker GJ, Webb S, Tofts PS, Thompson AJ, Harding AE, et al. Persistent functional deficit in multiple sclerosis and autosomal dominant cerebellar ataxia is associated with axon loss. Brain 1995; 188: 1583-92.
    • (1995) Brain , vol.188 , pp. 1583-1592
    • Davie, C.A.1    Barker, G.J.2    Webb, S.3    Tofts, P.S.4    Thompson, A.J.5    Harding, A.E.6
  • 6
    • 84974201150 scopus 로고
    • The histology of disseminated sclerosis
    • Dawson JW. The histology of disseminated sclerosis. Trans R Soc Edinb 1916; 50: 517-740.
    • (1916) Trans R Soc Edinb , vol.50 , pp. 517-740
    • Dawson, J.W.1
  • 7
    • 0031852514 scopus 로고    scopus 로고
    • Axonal damage correlates with disability in patients with relapsing-remitting multiple sclerosis. Results of a longitudinal magnetic resonance spectroscopy study
    • De Stefano N, Matthews PM, Fu L, Narayanan S, Stanley J, Francis GS, et al. Axonal damage correlates with disability in patients with relapsing-remitting multiple sclerosis. Results of a longitudinal magnetic resonance spectroscopy study. Brain 1998; 121: 1469-77.
    • (1998) Brain , vol.121 , pp. 1469-1477
    • De Stefano, N.1    Matthews, P.M.2    Fu, L.3    Narayanan, S.4    Stanley, J.5    Francis, G.S.6
  • 8
    • 0034104079 scopus 로고    scopus 로고
    • Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosis
    • Evangelou N, Esiri MM, Smith S, Palace J, Matthews PM. Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosis. Ann Neurol 2000a; 47: 391-5.
    • (2000) Ann Neurol , vol.47 , pp. 391-395
    • Evangelou, N.1    Esiri, M.M.2    Smith, S.3    Palace, J.4    Matthews, P.M.5
  • 9
    • 0033849266 scopus 로고    scopus 로고
    • Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis
    • Evangelou N, Konz D, Esiri MM, Smith S, Palace J, Matthews PM. Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis. Brain 2000b; 123: 1845-9.
    • (2000) Brain , vol.123 , pp. 1845-1849
    • Evangelou, N.1    Konz, D.2    Esiri, M.M.3    Smith, S.4    Palace, J.5    Matthews, P.M.6
  • 10
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • Ferguson B, Matyszak MK, Esiri MM, Perry VH. Axonal damage in acute multiple sclerosis lesions. Brain 1997; 120: 393-9.
    • (1997) Brain , vol.120 , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2    Esiri, M.M.3    Perry, V.H.4
  • 11
    • 0028815032 scopus 로고
    • Correlations between changes in disability and T2-weighted brain MRI activity in multiple sclerosis: A follow-up study
    • Filippi M, Paty DW, Kappos L, Barkhof F, Compston DA, Thompson AJ, et al. Correlations between changes in disability and T2-weighted brain MRI activity in multiple sclerosis: a follow-up study. Neurology 1995; 45: 255-60.
    • (1995) Neurology , vol.45 , pp. 255-260
    • Filippi, M.1    Paty, D.W.2    Kappos, L.3    Barkhof, F.4    Compston, D.A.5    Thompson, A.J.6
  • 12
    • 0033372792 scopus 로고    scopus 로고
    • Spinal cord axonal loss in multiple sclerosis; a post-mortern study
    • Ganter P, Prince C, Esiri MM. Spinal cord axonal loss in multiple sclerosis; a post-mortern study. Neuropathol Appl Neurobiol 1999; 25: 459-67.
    • (1999) Neuropathol Appl Neurobiol , vol.25 , pp. 459-467
    • Ganter, P.1    Prince, C.2    Esiri, M.M.3
  • 13
    • 0036189424 scopus 로고    scopus 로고
    • Patients lacking the major CNS myelin protein, proteolipid protein 1, develop length-dependent axonal degeneration in the absence of demyelination and inflammation
    • Garbern JY, Yool DA, Moore GJ, Wilds IB, Faulk MW, Klugmann M, et al. Patients lacking the major CNS myelin protein, proteolipid protein 1, develop length-dependent axonal degeneration in the absence of demyelination and inflammation. Brain 2002; 125: 551-61.
    • (2002) Brain , vol.125 , pp. 551-561
    • Garbern, J.Y.1    Yool, D.A.2    Moore, G.J.3    Wilds, I.B.4    Faulk, M.W.5    Klugmann, M.6
  • 14
    • 0032486428 scopus 로고    scopus 로고
    • Axonal swellings and degeneration in mice lacking the major proteolipid of myelin
    • Griffiths I, Klugmann M, Anderson T, Yool D, Thomson C, Schwab MH, et al. Axonal swellings and degeneration in mice lacking the major proteolipid of myelin. Science 1998; 280: 1610-3.
    • (1998) Science , vol.280 , pp. 1610-1613
    • Griffiths, I.1    Klugmann, M.2    Anderson, T.3    Yool, D.4    Thomson, C.5    Schwab, M.H.6
  • 15
    • 0033870097 scopus 로고    scopus 로고
    • Multiple sclerosis and chronic autoimmune encephalomyelitis. A comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions
    • Kornek B, Storch MK, Weissert R, Wallstroem E, Stefferl A, Olsson T, et al. Multiple sclerosis and chronic autoimmune encephalomyelitis. A comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions. Am J Pathol 2000; 157: 267-76.
    • (2000) Am J Pathol , vol.157 , pp. 267-276
    • Kornek, B.1    Storch, M.K.2    Weissert, R.3    Wallstroem, E.4    Stefferl, A.5    Olsson, T.6
  • 16
    • 0037678717 scopus 로고    scopus 로고
    • Axonal injury in multiple sclerosis
    • Lassmann H. Axonal injury in multiple sclerosis. J Neurol Neurosurg Psychiatry 2003; 74: 695-7.
    • (2003) J Neurol Neurosurg Psychiatry , vol.74 , pp. 695-697
    • Lassmann, H.1
  • 17
    • 8944248824 scopus 로고    scopus 로고
    • Spinal cord atrophy and disability in multiple sclerosis: A new reproducible and sensitive MRI method with potential to monitor disease progression
    • Losseff NA, Webb SL, O'Riordan JI, Page R, Wang L, Barker GJ, et al. Spinal cord atrophy and disability in multiple sclerosis: a new reproducible and sensitive MRI method with potential to monitor disease progression. Brain 1996; 119: 701-8.
    • (1996) Brain , vol.119 , pp. 701-708
    • Losseff, N.A.1    Webb, S.L.2    O'Riordan, J.I.3    Page, R.4    Wang, L.5    Barker, G.J.6
  • 18
    • 0342288638 scopus 로고    scopus 로고
    • Axonal changes in chronic demyelinated cervical spinal cord plaques
    • Lovas G, Szilagyi N, Majtenyi K, Palkovits M, Komoly S. Axonal changes in chronic demyelinated cervical spinal cord plaques. Brain 2000; 123: 308-17.
    • (2000) Brain , vol.123 , pp. 308-317
    • Lovas, G.1    Szilagyi, N.2    Majtenyi, K.3    Palkovits, M.4    Komoly, S.5
  • 19
    • 0015235073 scopus 로고
    • The immunogenesis of the multiple sclerosis plaque
    • Lumsden CE. The immunogenesis of the multiple sclerosis plaque. Brain Res 1971; 28: 365-90.
    • (1971) Brain Res , vol.28 , pp. 365-390
    • Lumsden, C.E.1
  • 21
    • 0022548749 scopus 로고
    • Pathogenesis of multiple sclerosis. A critical reappraisal
    • Poser CM. Pathogenesis of multiple sclerosis. A critical reappraisal. Acta Neuropathol (Berl) 1986; 71: 1-10.
    • (1986) Acta Neuropathol (Berl) , vol.71 , pp. 1-10
    • Poser, C.M.1
  • 22
    • 0032948049 scopus 로고    scopus 로고
    • Axonal pathology in demyelinating diseases
    • Scherer S. Axonal pathology in demyelinating diseases. Ann Neurol 1999; 45: 6-7.
    • (1999) Ann Neurol , vol.45 , pp. 6-7
    • Scherer, S.1
  • 23
    • 0029748591 scopus 로고    scopus 로고
    • Compression injury of mammalian spinal cord in vitro and the dynamics of action potential conduction failure
    • Shi R, Blight AR. Compression injury of mammalian spinal cord in vitro and the dynamics of action potential conduction failure. J Neurophysiol 1996; 76: 1572-80.
    • (1996) J Neurophysiol , vol.76 , pp. 1572-1580
    • Shi, R.1    Blight, A.R.2
  • 24
    • 0034646386 scopus 로고    scopus 로고
    • A Wallerian degeneration pattern in patients at risk for MS
    • Simon JK, Kinkel RP, Jacobs L, Bub L, Simonian N. A Wallerian degeneration pattern in patients at risk for MS. Neurology 2000; 54: 1155-60.
    • (2000) Neurology , vol.54 , pp. 1155-1160
    • Simon, J.K.1    Kinkel, R.P.2    Jacobs, L.3    Bub, L.4    Simonian, N.5
  • 26
    • 0036136532 scopus 로고    scopus 로고
    • Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis
    • Wujek JR, Bjartmar C, Richer E, Ransohoff RM, Yu M, Tuohy VK, et al. Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis. J Neuropathol Exp Neurol 2002; 61: 23-32.
    • (2002) J Neuropathol Exp Neurol , vol.61 , pp. 23-32
    • Wujek, J.R.1    Bjartmar, C.2    Richer, E.3    Ransohoff, R.M.4    Yu, M.5    Tuohy, V.K.6
  • 27
    • 0032521342 scopus 로고    scopus 로고
    • Myelin-associated glycoprotein is a myelin signal that modulates the caliber of myelinated axons
    • Yin X, Crawford TO, Griffin JW, Tu P, Lee VM, Li C, et al. Myelin-associated glycoprotein is a myelin signal that modulates the caliber of myelinated axons. J Neurosci 1998; 18: 1953-62.
    • (1998) J Neurosci , vol.18 , pp. 1953-1962
    • Yin, X.1    Crawford, T.O.2    Griffin, J.W.3    Tu, P.4    Lee, V.M.5    Li, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.