AKT/mTOR and c-Jun N-terminal kinase signaling pathways are required for chrysotile asbestos-induced autophagy

Free Radical Biology and Medicine

Volumn 72, Issue , 2014, Pages 296-307

  Lin, Ziying ^a   Liu, Tie ^b   Kamp, David W ^c   Wang, Yahong ^a   He, Huijuan ^a   Zhou, Xu ^a   Li, Donghong ^a   Yang, Lawei ^a   Zhao, Bin ^a   Liu, Gang ^a  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

^b MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

A549 cells; Autophagy; Chrysotile asbestos; Free radicals; LC3 II; Pulmonary disease

Indexed keywords

3 METHYLADENINE; ACETYLCYSTEINE; AUTOPHAGY PROTEIN 5; CHRYSOTILE; MAMMALIAN TARGET OF RAPAMYCIN; MICROTUBULE ASSOCIATED PROTEIN 1; MITOGEN ACTIVATED PROTEIN KINASE 14; PROTEIN KINASE B; S6 KINASE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL SURVIVAL; CONTROLLED STUDY; DEPHOSPHORYLATION; EMBRYO; EPITHELIUM CELL; FIBROBLAST; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; COCULTURE; CYTOLOGY; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSFECTION; LUNG; METABOLISM; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TOXICITY; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

ANIMALS; ASBESTOS, SERPENTINE; AUTOPHAGY; BLOTTING, WESTERN; CELL LINE; COCULTURE TECHNIQUES; EPITHELIAL CELLS; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LUNG; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRANSFECTION;

EID: 84902162904     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.04.004     Document Type: Article

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