Antibodies against specific extracellular epitopes of the glucagon receptor block glucagon binding

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 1, 1996, Pages 310-315

  Unson, Cecilia G ^a   Cypess, Aaron M ^a   Wu, Cui Rong ^a   Goldsmith, Paul K ^c   Merrifield, R B ^a   Sakmar, Thomas P ^a,b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

antigen; G protein; hormone receptor; peptide; signal transduction

Indexed keywords

ADENYLATE CYCLASE; EPITOPE; GLUCAGON ANTIBODY; GLUCAGON RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HORMONE RECEPTOR BLOCKING AGENT; POLYCLONAL ANTIBODY; SYNTHETIC PEPTIDE;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; CELL STRAIN COS1; CONTROLLED STUDY; HORMONE RECEPTOR INTERACTION; IMMUNOFLUORESCENCE MICROSCOPY; LIGAND BINDING; LIVER MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION;

ADENYLATE CYCLASE; AMINO ACID SEQUENCE; ANIMALS; ANTIGEN-ANTIBODY REACTIONS; BINDING, COMPETITIVE; CELL MEMBRANE; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; ENZYME ACTIVATION; EPITOPE MAPPING; EPITOPES; EXTRACELLULAR SPACE; GLUCAGON; LIVER; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; RATS; RECEPTORS, GLUCAGON; SIGNAL TRANSDUCTION; TRANSFECTION;

ANIMALIA;

EID: 0030025597     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.1.310     Document Type: Article

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