-
1
-
-
84859366447
-
Protease signalling: the cutting edge
-
Turk, B., Turk, D., Turk, V., Protease signalling: the cutting edge. EMBO J. 2012, 31, 1630-1643.
-
(2012)
EMBO J.
, vol.31
, pp. 1630-1643
-
-
Turk, B.1
Turk, D.2
Turk, V.3
-
2
-
-
33748308883
-
Targeting proteases: successes, failures and future prospects
-
Turk, B., Targeting proteases: successes, failures and future prospects. Nat. Rev. Drug Discov. 2006, 5, 785-799.
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 785-799
-
-
Turk, B.1
-
3
-
-
77956310878
-
Emerging principles in protease-based drug discovery
-
Drag, M., Salvesen, G. S., Emerging principles in protease-based drug discovery. Nat. Rev. Drug Discov. 2010, 9, 690-701.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 690-701
-
-
Drag, M.1
Salvesen, G.S.2
-
4
-
-
0036716282
-
Strategies for MMP inhibition in cancer: innovations for the post-trial era
-
Overall, C. M., López-Otín, C., Strategies for MMP inhibition in cancer: innovations for the post-trial era. Nat. Rev. Cancer 2002, 2, 657-672.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 657-672
-
-
Overall, C.M.1
López-Otín, C.2
-
5
-
-
0037192458
-
Matrix metalloproteinase inhibitors and cancer: trials and tribulations
-
Coussens, L. M., Fingleton, B., Matrisian, L. M., Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 2002, 295, 2387-2392.
-
(2002)
Science
, vol.295
, pp. 2387-2392
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
-
6
-
-
84859426282
-
MEROPS: the database of proteolytic enzymes, their substrates and inhibitors
-
Rawlings, N. D., Barrett, A. J., Bateman, A., MEROPS: the database of proteolytic enzymes, their substrates and inhibitors. Nucleic Acids Res. 2012, 40, D343-D350.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Rawlings, N.D.1
Barrett, A.J.2
Bateman, A.3
-
7
-
-
0345310073
-
Revised definition of substrate binding sites of papain-like cysteine proteases
-
Turk, D., Guncar, G., Podobnik, M., Turk, B., Revised definition of substrate binding sites of papain-like cysteine proteases. Biol. Chem. 1998, 379, 137-147.
-
(1998)
Biol. Chem.
, vol.379
, pp. 137-147
-
-
Turk, D.1
Guncar, G.2
Podobnik, M.3
Turk, B.4
-
8
-
-
82755161948
-
Cysteine cathepsins: from structure, function and regulation to new frontiers
-
Turk, V., Stoka, V., Vasiljeva, O., Renko, M. et al., Cysteine cathepsins: from structure, function and regulation to new frontiers. Biochim. Biophys. Acta 2012, 1824, 68-88.
-
(2012)
Biochim. Biophys. Acta
, vol.1824
, pp. 68-88
-
-
Turk, V.1
Stoka, V.2
Vasiljeva, O.3
Renko, M.4
-
9
-
-
69249227502
-
Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function
-
Saftig, P., Klumperman, J., Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function. Nat. Rev. Mol. Cell Biol. 2009, 10, 623-635.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 623-635
-
-
Saftig, P.1
Klumperman, J.2
-
10
-
-
1942470581
-
A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor
-
Goulet, B., Baruch, A., Moon, N. S., Poirier, M. et al., A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor. Mol. Cell 2004, 14, 207-219.
-
(2004)
Mol. Cell
, vol.14
, pp. 207-219
-
-
Goulet, B.1
Baruch, A.2
Moon, N.S.3
Poirier, M.4
-
11
-
-
53549094681
-
Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation
-
Duncan, E. M., Muratore-Schroeder, T. L., Cook, R. G., Garcia, B. A. et al., Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell 2008, 135, 284-294.
-
(2008)
Cell
, vol.135
, pp. 284-294
-
-
Duncan, E.M.1
Muratore-Schroeder, T.L.2
Cook, R.G.3
Garcia, B.A.4
-
12
-
-
58149260198
-
Histone H3 tail clipping regulates gene expression
-
Santos-Rosa, H., Kirmizis, A., Nelson, C., Bartke, T. et al., Histone H3 tail clipping regulates gene expression. Nat. Struct. Mol. Biol. 2009, 16, 17-22.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 17-22
-
-
Santos-Rosa, H.1
Kirmizis, A.2
Nelson, C.3
Bartke, T.4
-
13
-
-
84868119552
-
Structural basis for the recognition and cleavage of histone H3 by cathepsin L
-
Adams-Cioaba, M. A., Krupa, J. C., Xu, C., Mort, J. S., Min, J., Structural basis for the recognition and cleavage of histone H3 by cathepsin L. Nat. Commun. 2011, 2, 197.
-
(2011)
Nat. Commun.
, vol.2
, pp. 197
-
-
Adams-Cioaba, M.A.1
Krupa, J.C.2
Xu, C.3
Mort, J.S.4
Min, J.5
-
14
-
-
77951237963
-
Stefin B interacts with histones and cathepsin L in the nucleus
-
Ceru, S., Konjar, S., Maher, K., Repnik, U. et al., Stefin B interacts with histones and cathepsin L in the nucleus. J. Biol. Chem. 2010, 285, 10078-10086.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 10078-10086
-
-
Ceru, S.1
Konjar, S.2
Maher, K.3
Repnik, U.4
-
15
-
-
57349176440
-
Nuclear cathepsin F regulates activation markers in rat hepatic stellate cells
-
Maubach, G., Lim, M. C., Zhuo, L., Nuclear cathepsin F regulates activation markers in rat hepatic stellate cells. Mol. Biol. Cell 2008, 19, 4238-4248.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 4238-4248
-
-
Maubach, G.1
Lim, M.C.2
Zhuo, L.3
-
16
-
-
77955957035
-
Nuclear cysteine cathepsin variants in thyroid carcinoma cells
-
Tedelind, S., Poliakova, K., Valeta, A., Hunegnaw, R. et al., Nuclear cysteine cathepsin variants in thyroid carcinoma cells. Biol. Chem. 2010, 391, 923-935.
-
(2010)
Biol. Chem.
, vol.391
, pp. 923-935
-
-
Tedelind, S.1
Poliakova, K.2
Valeta, A.3
Hunegnaw, R.4
-
17
-
-
33846643454
-
Cysteine cathepsins and the cutting edge of cancer invasion
-
Gocheva, V., Joyce, J. A., Cysteine cathepsins and the cutting edge of cancer invasion. Cell Cycle 2007, 6, 60-64.
-
(2007)
Cell Cycle
, vol.6
, pp. 60-64
-
-
Gocheva, V.1
Joyce, J.A.2
-
18
-
-
0028618307
-
Pericellular pH affects distribution and secretion of cathepsin B in malignant cells
-
Rozhin, J., Sameni, M., Ziegler, G., Sloane, B. F., Pericellular pH affects distribution and secretion of cathepsin B in malignant cells. Cancer Res. 1994, 54, 6517-6525.
-
(1994)
Cancer Res.
, vol.54
, pp. 6517-6525
-
-
Rozhin, J.1
Sameni, M.2
Ziegler, G.3
Sloane, B.F.4
-
19
-
-
0347683401
-
Mutant K-ras regulates cathepsin B localization on the surface of human colorectal carcinoma cells
-
Cavallo-Medved, D., Dosescu, J., Linebaugh, B. E., Sameni, M. et al., Mutant K-ras regulates cathepsin B localization on the surface of human colorectal carcinoma cells. Neoplasia 2003, 5, 507-519.
-
(2003)
Neoplasia
, vol.5
, pp. 507-519
-
-
Cavallo-Medved, D.1
Dosescu, J.2
Linebaugh, B.E.3
Sameni, M.4
-
20
-
-
33144488633
-
Localization of cysteine protease, cathepsin S, to the surface of vascular smooth muscle cells by association with integrin alphanubeta3
-
Cheng, X. W., Kuzuya, M., Nakamura, K., Di, Q. et al., Localization of cysteine protease, cathepsin S, to the surface of vascular smooth muscle cells by association with integrin alphanubeta3. Am J. Pathol. 2006, 168, 685-694.
-
(2006)
Am J. Pathol.
, vol.168
, pp. 685-694
-
-
Cheng, X.W.1
Kuzuya, M.2
Nakamura, K.3
Di, Q.4
-
21
-
-
42149134396
-
Cysteine protease cathepsin X modulates immune response via activation of beta2 integrins
-
Obermajer, N., Repnik, U., Jevnikar, Z., Turk, B. et al., Cysteine protease cathepsin X modulates immune response via activation of beta2 integrins. Immunology 2008, 124, 76-88.
-
(2008)
Immunology
, vol.124
, pp. 76-88
-
-
Obermajer, N.1
Repnik, U.2
Jevnikar, Z.3
Turk, B.4
-
22
-
-
15844422855
-
Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts
-
Drake, F. H., Dodds, R. A., James, I. E., Connor, J. R. et al., Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts. J. Biol. Chem. 1996, 271, 12511-12516.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12511-12516
-
-
Drake, F.H.1
Dodds, R.A.2
James, I.E.3
Connor, J.R.4
-
23
-
-
0035127395
-
Biosynthesis and processing of cathepsin K in cultured human osteoclasts
-
Rieman, D. J., McClung, H. A., Dodds, R. A., Hwang, S. M. et al., Biosynthesis and processing of cathepsin K in cultured human osteoclasts. Bone 2001, 28, 282-289.
-
(2001)
Bone
, vol.28
, pp. 282-289
-
-
Rieman, D.J.1
McClung, H.A.2
Dodds, R.A.3
Hwang, S.M.4
-
24
-
-
0038481173
-
Thyroid functions of mouse cathepsins B, K, and L
-
Friedrichs, B., Tepel, C., Reinheckel, T., Deussing, J. et al., Thyroid functions of mouse cathepsins B, K, and L. J. Clin. Invest. 2003, 111, 1733-1745.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1733-1745
-
-
Friedrichs, B.1
Tepel, C.2
Reinheckel, T.3
Deussing, J.4
-
25
-
-
19944429298
-
HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration
-
Büth, H., Wolters, B., Hartwig, B., Meier-Bornheim, R. et al., HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration. Eur. J. Cell Biol. 2004, 83, 781-795.
-
(2004)
Eur. J. Cell Biol.
, vol.83
, pp. 781-795
-
-
Büth, H.1
Wolters, B.2
Hartwig, B.3
Meier-Bornheim, R.4
-
26
-
-
0035986219
-
Regulating cysteine protease activity: essential role of protease inhibitors as guardians and regulators
-
Turk, B., Turk, D., Salvesen, G. S., Regulating cysteine protease activity: essential role of protease inhibitors as guardians and regulators. Curr. Pharm. Des. 2002, 8, 1623-1637.
-
(2002)
Curr. Pharm. Des.
, vol.8
, pp. 1623-1637
-
-
Turk, B.1
Turk, D.2
Salvesen, G.S.3
-
27
-
-
33846164404
-
Emerging roles of cysteine cathepsins in disease and their potential as drug targets
-
Vasiljeva, O., Reinheckel, T., Peters, C., Turk, D. et al., Emerging roles of cysteine cathepsins in disease and their potential as drug targets. Curr. Pharm. Des. 2007, 13, 387-403.
-
(2007)
Curr. Pharm. Des.
, vol.13
, pp. 387-403
-
-
Vasiljeva, O.1
Reinheckel, T.2
Peters, C.3
Turk, D.4
-
28
-
-
77957855881
-
Specialized roles for cysteine cathepsins in health and disease
-
Reiser, J., Adair, B., Reinheckel, T., Specialized roles for cysteine cathepsins in health and disease. J. Clin. Invest. 2010, 120, 3421-3431.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 3421-3431
-
-
Reiser, J.1
Adair, B.2
Reinheckel, T.3
-
29
-
-
0029310512
-
Human cathepsin O2, a novel cysteine protease highly expressed in osteoclastomas and ovary molecular cloning, sequencing and tissue distribution
-
Brömme, D., Okamoto, K., Human cathepsin O2, a novel cysteine protease highly expressed in osteoclastomas and ovary molecular cloning, sequencing and tissue distribution. Biol. Chem. Hoppe. Seyler. 1995, 376, 379-384.
-
(1995)
Biol. Chem. Hoppe. Seyler.
, vol.376
, pp. 379-384
-
-
Brömme, D.1
Okamoto, K.2
-
30
-
-
0032080113
-
Human cathepsin K cleaves native type I and II collagens at the N-terminal end of the triple helix
-
Kafienah, W., Brömme, D., Buttle, D. J., Croucher, L. J., Hollander, A. P., Human cathepsin K cleaves native type I and II collagens at the N-terminal end of the triple helix. Biochem. J. 1998, 331, 727-732.
-
(1998)
Biochem. J.
, vol.331
, pp. 727-732
-
-
Kafienah, W.1
Brömme, D.2
Buttle, D.J.3
Croucher, L.J.4
Hollander, A.P.5
-
31
-
-
0030869303
-
Peptide aldehyde inhibitors of cathepsin K inhibit bone resorption both in vitro and in vivo
-
Votta, B. J., Levy, M. A., Badger, A., Bradbeer, J. et al., Peptide aldehyde inhibitors of cathepsin K inhibit bone resorption both in vitro and in vivo. J. Bone Miner. Res. 1997, 12, 1396-1406.
-
(1997)
J. Bone Miner. Res.
, vol.12
, pp. 1396-1406
-
-
Votta, B.J.1
Levy, M.A.2
Badger, A.3
Bradbeer, J.4
-
32
-
-
0030984531
-
Cathepsin K antisense oligodeoxynucleotide inhibits osteoclastic bone resorption
-
Inui, T., Ishibashi, O., Inaoka, T., Origane, Y. et al., Cathepsin K antisense oligodeoxynucleotide inhibits osteoclastic bone resorption. J. Biol. Chem. 1997, 272, 8109-8112.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8109-8112
-
-
Inui, T.1
Ishibashi, O.2
Inaoka, T.3
Origane, Y.4
-
33
-
-
0032506007
-
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice
-
Saftig, P., Hunziker, E., Wehmeyer, O., Jones, S. et al., Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice. Proc. Natl. Acad. Sci. USA 1998, 95, 13453-13458.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13453-13458
-
-
Saftig, P.1
Hunziker, E.2
Wehmeyer, O.3
Jones, S.4
-
34
-
-
0029809357
-
Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency
-
Gelb, B. D., Shi, G. P., Chapman, H. A., Desnick, R. J., Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency. Science 1996, 273, 1236-1238.
-
(1996)
Science
, vol.273
, pp. 1236-1238
-
-
Gelb, B.D.1
Shi, G.P.2
Chapman, H.A.3
Desnick, R.J.4
-
35
-
-
84887618813
-
Osteoporosis-a current view of pharmacological prevention and treatment
-
Das, S., Crockett, J. C., Osteoporosis-a current view of pharmacological prevention and treatment. Drug Des. Devel. Ther. 2013, 7, 435-448.
-
(2013)
Drug Des. Devel. Ther.
, vol.7
, pp. 435-448
-
-
Das, S.1
Crockett, J.C.2
-
36
-
-
0026507880
-
Proteoglycans: many forms and many functions
-
Hardingham, T. E., Fosang, A. J., Proteoglycans: many forms and many functions. FASEB J. 1992, 6, 861-870.
-
(1992)
FASEB J.
, vol.6
, pp. 861-870
-
-
Hardingham, T.E.1
Fosang, A.J.2
-
37
-
-
1042267249
-
Osteoarthritis: is it a disease of cartilage or bone
-
Felson, D. T., Neogi, T., Osteoarthritis: is it a disease of cartilage or bone? Arthritis Rheum. 2004, 50, 341-344.
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 341-344
-
-
Felson, D.T.1
Neogi, T.2
-
38
-
-
40349087284
-
Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: destruction or repair
-
Murphy, G., Nagase, H., Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: destruction or repair? Nat. Clin. Pract. Rheumatol. 2008, 4, 128-135.
-
(2008)
Nat. Clin. Pract. Rheumatol.
, vol.4
, pp. 128-135
-
-
Murphy, G.1
Nagase, H.2
-
39
-
-
0029091894
-
Control of matrix synthesis in isolated bovine chondrocytes by extracellular and intracellular pH
-
Wilkins, R. J., Hall, A. C., Control of matrix synthesis in isolated bovine chondrocytes by extracellular and intracellular pH. J. Cell Physiol. 1995, 164, 474-481.
-
(1995)
J. Cell Physiol.
, vol.164
, pp. 474-481
-
-
Wilkins, R.J.1
Hall, A.C.2
-
40
-
-
0036226928
-
Acidic cysteine endoproteinase cathepsin K in the degeneration of the superficial articular hyaline cartilage in osteoarthritis
-
Konttinen, Y. T., Mandelin, J., Li, T. F., Salo, J. et al., Acidic cysteine endoproteinase cathepsin K in the degeneration of the superficial articular hyaline cartilage in osteoarthritis. Arthritis Rheum. 2002, 46, 953-960.
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 953-960
-
-
Konttinen, Y.T.1
Mandelin, J.2
Li, T.F.3
Salo, J.4
-
41
-
-
3442875303
-
Pathogenesis of bone and cartilage destruction in rheumatoid arthritis
-
ii11-iii6
-
Goldring, S. R., Pathogenesis of bone and cartilage destruction in rheumatoid arthritis. Rheumatology 2003, 42(Suppl 2), ii11-ii6.
-
(2003)
Rheumatology
, vol.42
, Issue.SUPPL. 2
-
-
Goldring, S.R.1
-
42
-
-
0023886162
-
Human cathepsin B and cysteine-proteinase inhibitors (CPIs) in inflamatory and metabolic join diseases
-
Lenarčič, B., Gabrijelčič, D., Rozman, B., Drobnič-Košorok, M., Turk, V., Human cathepsin B and cysteine-proteinase inhibitors (CPIs) in inflamatory and metabolic join diseases. Biol. Chem. Hoppe Seyler 1988, 369, 257-261.
-
(1988)
Biol. Chem. Hoppe Seyler
, vol.369
, pp. 257-261
-
-
Lenarčič, B.1
Gabrijelčič, D.2
Rozman, B.3
Drobnič-Košorok, M.4
Turk, V.5
-
43
-
-
0025220324
-
Determination of cathepsins B and H in sera and synovial fluids of patients with different joint diseases
-
Gabrijelcic, D., Annan-Prah, A., Rodic, B., Rozman, B. et al., Determination of cathepsins B and H in sera and synovial fluids of patients with different joint diseases. J. Clin. Chem. Clin. Biochem. 1990, 28, 149-153.
-
(1990)
J. Clin. Chem. Clin. Biochem.
, vol.28
, pp. 149-153
-
-
Gabrijelcic, D.1
Annan-Prah, A.2
Rodic, B.3
Rozman, B.4
-
44
-
-
0030837038
-
Selective induction of the secretion of cathepsins B and L by cytokines in synovial fibroblast-like cells
-
Lemaire, R., Huet, G., Zerimech, F., Grard, G. et al., Selective induction of the secretion of cathepsins B and L by cytokines in synovial fibroblast-like cells. Br. J. Rheumatol. 1997, 36, 735-743.
-
(1997)
Br. J. Rheumatol.
, vol.36
, pp. 735-743
-
-
Lemaire, R.1
Huet, G.2
Zerimech, F.3
Grard, G.4
-
45
-
-
0034096934
-
Cathepsin B and its endogenous inhibitor cystetin C in rheumatoid arthritis synovium
-
Hansen, T., Petrow, P. K., Gaumann, A., Keyzser, G. M. et al., Cathepsin B and its endogenous inhibitor cystetin C in rheumatoid arthritis synovium. J. Rheumatol. 2000, 27, 859-865.
-
(2000)
J. Rheumatol.
, vol.27
, pp. 859-865
-
-
Hansen, T.1
Petrow, P.K.2
Gaumann, A.3
Keyzser, G.M.4
-
46
-
-
77952798828
-
Expression and activity profiling of selected cysteine proteases and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis
-
Požgan, U., Caglič, D., Rozman, B., Nagase, H. et al., Expression and activity profiling of selected cysteine proteases and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis. Biol. Chem. 2010, 391, 571-579.
-
(2010)
Biol. Chem.
, vol.391
, pp. 571-579
-
-
Požgan, U.1
Caglič, D.2
Rozman, B.3
Nagase, H.4
-
47
-
-
0028901908
-
Cathepsin B in osteoarthritis: cytochemical and histochemical analysis of human femoral head cartilage
-
Baici, A., Lang, A., Horler, D., Kissling, R., Merlin, C., Cathepsin B in osteoarthritis: cytochemical and histochemical analysis of human femoral head cartilage. Ann. Rheum. Dis. 1995, 54, 289-297.
-
(1995)
Ann. Rheum. Dis.
, vol.54
, pp. 289-297
-
-
Baici, A.1
Lang, A.2
Horler, D.3
Kissling, R.4
Merlin, C.5
-
48
-
-
0028907722
-
Cathepsin B in osteoarthritis: zonal variation of enzyme activity in human femoral head cartilage
-
Baici, A., Horler, D., Lang, A., Merlin, C., Kissling, R., Cathepsin B in osteoarthritis: zonal variation of enzyme activity in human femoral head cartilage. Ann. Rheum. Dis. 1995, 54, 281-288.
-
(1995)
Ann. Rheum. Dis.
, vol.54
, pp. 281-288
-
-
Baici, A.1
Horler, D.2
Lang, A.3
Merlin, C.4
Kissling, R.5
-
49
-
-
1342304427
-
Early diagnosis of osteoarthritis using cathepsin B sensitive near-infrared fluorescent probes
-
Lai, W. F., Chang, C. H., Tang, Y., Bronson, R., Tung, C. H., Early diagnosis of osteoarthritis using cathepsin B sensitive near-infrared fluorescent probes. Osteoarthr. Cartil. 2004, 12, 239-244.
-
(2004)
Osteoarthr. Cartil.
, vol.12
, pp. 239-244
-
-
Lai, W.F.1
Chang, C.H.2
Tang, Y.3
Bronson, R.4
Tung, C.H.5
-
50
-
-
0036185401
-
Comparison of cathepsins K and S expression within the rheumatoid and osteoarthritic synovium
-
Hou, W. S., Li, W., Keyszer, G., Comparison of cathepsins K and S expression within the rheumatoid and osteoarthritic synovium. Arthritis Rheum. 2002, 46, 663-674.
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 663-674
-
-
Hou, W.S.1
Li, W.2
Keyszer, G.3
-
51
-
-
0035185895
-
Cathepsin K is a critical protease in synovial fibroblast mediated collagen degradation
-
Hou, W. S., Li, Z., Gordon, R. E., Chan, K. et al., Cathepsin K is a critical protease in synovial fibroblast mediated collagen degradation. Am J Pathol 2001, 159, 2167-2177.
-
(2001)
Am J Pathol
, vol.159
, pp. 2167-2177
-
-
Hou, W.S.1
Li, Z.2
Gordon, R.E.3
Chan, K.4
-
52
-
-
0038486755
-
Cleavage site specificity of cathepsin K toward cartilage proteoglycans and protease complex formation
-
Hou, W. S., Li, Z., Buttner, F. H., Bartnik, E., Bromme, D., Cleavage site specificity of cathepsin K toward cartilage proteoglycans and protease complex formation. Biol. Chem. 2003, 384, 891-897.
-
(2003)
Biol. Chem.
, vol.384
, pp. 891-897
-
-
Hou, W.S.1
Li, Z.2
Buttner, F.H.3
Bartnik, E.4
Bromme, D.5
-
53
-
-
84859061110
-
Role for cysteine protease cathepsins in heart disease: focus on biology and mechanisms with clinical implication
-
Cheng, X. W., Shi, G. P., Kuzuya, M., Sasaki, T. et al., Role for cysteine protease cathepsins in heart disease: focus on biology and mechanisms with clinical implication. Circulation 2012, 125, 1551-1562.
-
(2012)
Circulation
, vol.125
, pp. 1551-1562
-
-
Cheng, X.W.1
Shi, G.P.2
Kuzuya, M.3
Sasaki, T.4
-
54
-
-
33750246799
-
Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertension heart failure
-
Cheng, X. W., Obata, K., Kuzuya, M., Izawa, H. et al., Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertension heart failure. Hypertension 2006, 48, 979-987.
-
(2006)
Hypertension
, vol.48
, pp. 979-987
-
-
Cheng, X.W.1
Obata, K.2
Kuzuya, M.3
Izawa, H.4
-
55
-
-
18344376711
-
Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L
-
Stypmann, J., Glaser, K., Roth, W., Tobin, D. J. et al., Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L. Proc. Natl. Acad. Sci. USA 2002, 99, 6234-6239.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6234-6239
-
-
Stypmann, J.1
Glaser, K.2
Roth, W.3
Tobin, D.J.4
-
56
-
-
33845652579
-
Lysosomal, cytosceletal and metabolic alterations in cardiomyopathy of cathepsin L knockout mice
-
Petermann, I., Mayer, C., Stypmann, J., Biniossek, M. L. et al., Lysosomal, cytosceletal and metabolic alterations in cardiomyopathy of cathepsin L knockout mice. FASEB J. 2006, 20, 1266-1268.
-
(2006)
FASEB J.
, vol.20
, pp. 1266-1268
-
-
Petermann, I.1
Mayer, C.2
Stypmann, J.3
Biniossek, M.L.4
-
57
-
-
60549104999
-
Lysosomal cysteine peptidase cathepsin L protects against cardiac hyperthrophy through blocking AKT/GSK3beta signaling
-
Tang, Q., Cai, J., Shen, D., Bian, Z. et al., Lysosomal cysteine peptidase cathepsin L protects against cardiac hyperthrophy through blocking AKT/GSK3beta signaling. J. Mol. Med. 2006, 87, 249-260.
-
(2006)
J. Mol. Med.
, vol.87
, pp. 249-260
-
-
Tang, Q.1
Cai, J.2
Shen, D.3
Bian, Z.4
-
58
-
-
20044373820
-
Cathepsin L is required for endothelial progenitor cell induced neovascularisation
-
Urbich, C., Heeschen, C., Aicher, A., Sasaki, K. et al., Cathepsin L is required for endothelial progenitor cell induced neovascularisation. Nat. Med. 2005, 11, 206-213.
-
(2005)
Nat. Med.
, vol.11
, pp. 206-213
-
-
Urbich, C.1
Heeschen, C.2
Aicher, A.3
Sasaki, K.4
-
59
-
-
78751469546
-
Cathepsin L contributes to cardiac repair and remodeling post-infarction
-
Sun, M, Chen, M., Liu, Y., Fukuoka, M. et al., Cathepsin L contributes to cardiac repair and remodeling post-infarction. Cardiovasc. Res. 2010, 89, 374-383.
-
(2010)
Cardiovasc. Res.
, vol.89
, pp. 374-383
-
-
Sun, M.1
Chen, M.2
Liu, Y.3
Fukuoka, M.4
-
60
-
-
78751469546
-
Cathepsin-L contributes to cardiac repair and remodelling post-infarction
-
Sun, M., Chen, M., Liu, Y., Fukuoka, M. et al., Cathepsin-L contributes to cardiac repair and remodelling post-infarction. Cardiovasc. Res. 2011, 89, 374-383.
-
(2011)
Cardiovasc. Res.
, vol.89
, pp. 374-383
-
-
Sun, M.1
Chen, M.2
Liu, Y.3
Fukuoka, M.4
-
61
-
-
33746834187
-
Increased expression of elastolytic cathepsins S, K and V and their inhibitor cystatin C in stenotic aortic valves
-
Helske, S., Syvaranta, S., Lindstedt, K. A., Lappalainen, J. et al., Increased expression of elastolytic cathepsins S, K and V and their inhibitor cystatin C in stenotic aortic valves. Arterioscler. Thromb. Vasc. Biol. 2006, 26, 1791-1798.
-
(2006)
Arterioscler. Thromb. Vasc. Biol.
, vol.26
, pp. 1791-1798
-
-
Helske, S.1
Syvaranta, S.2
Lindstedt, K.A.3
Lappalainen, J.4
-
62
-
-
64049108554
-
Elevated cyclic stretch alters matrix remodeling in aortic valve cusps: implications for degenerative aortic valve disease
-
Balachandran, K., Sucosky, P., Jo, H., Yoganathan, A. P., Elevated cyclic stretch alters matrix remodeling in aortic valve cusps: implications for degenerative aortic valve disease. Am. J. Physiol. Heart Circ. Physiol. 2009, 296, H756-H764.
-
(2009)
Am. J. Physiol. Heart Circ. Physiol.
, vol.296
-
-
Balachandran, K.1
Sucosky, P.2
Jo, H.3
Yoganathan, A.P.4
-
63
-
-
77954568359
-
Elevated cyclic stretch induces aortic valve calcification in a bone morphogenic protein dependant manner
-
Balachandran, K., Sucosky, P., Jo, H., Yoganathan, A. P., Elevated cyclic stretch induces aortic valve calcification in a bone morphogenic protein dependant manner. Am. J. Pathol. 2010, 177, 49-57.
-
(2010)
Am. J. Pathol.
, vol.177
, pp. 49-57
-
-
Balachandran, K.1
Sucosky, P.2
Jo, H.3
Yoganathan, A.P.4
-
64
-
-
65349154635
-
Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease
-
Aikawa, E., Aikawa, M., Libby, P., Figueiredo, J. L. et al., Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease. Circulation 2009, 119, 1785-1794.
-
(2009)
Circulation
, vol.119
, pp. 1785-1794
-
-
Aikawa, E.1
Aikawa, M.2
Libby, P.3
Figueiredo, J.L.4
-
65
-
-
0032145836
-
Expression of elastinolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells
-
Sukhova, G. K., Shi, G. P., Simon, D. I., Chapman, H. A., Libby, P., Expression of elastinolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells. J. Clin. Invest. 1998, 102, 576-583.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 576-583
-
-
Sukhova, G.K.1
Shi, G.P.2
Simon, D.I.3
Chapman, H.A.4
Libby, P.5
-
66
-
-
0036735233
-
Differential expression of cysteine and aspartic proteases during progression of atherosclerosis in apolipoprotein E-defficient mice
-
Jormsjo, S., Wuttge, D. M., Sirsjo, A., Whatling, C. et al., Differential expression of cysteine and aspartic proteases during progression of atherosclerosis in apolipoprotein E-defficient mice. Am. J. Pathol. 2002, 161, 939-946.
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 939-946
-
-
Jormsjo, S.1
Wuttge, D.M.2
Sirsjo, A.3
Whatling, C.4
-
67
-
-
0029007093
-
Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages
-
Reddy, V. Y., Zhang, Q. Y., Weiss, S. J., Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages. Proc. Natl. Acad Sci. USA 1995, 92, 3849-3853.
-
(1995)
Proc. Natl. Acad Sci. USA
, vol.92
, pp. 3849-3853
-
-
Reddy, V.Y.1
Zhang, Q.Y.2
Weiss, S.J.3
-
68
-
-
33646710817
-
Destabilizing role of cathepsin S in murine atherosclerotic plaques
-
Rodgers, K. J., Watkins, D. J., Miller, A. L., Chan, P. Y. et al., Destabilizing role of cathepsin S in murine atherosclerotic plaques. Arterioscler. Thromb. Vasc. Biol. 2006, 26, 851-856.
-
(2006)
Arterioscler. Thromb. Vasc. Biol.
, vol.26
, pp. 851-856
-
-
Rodgers, K.J.1
Watkins, D.J.2
Miller, A.L.3
Chan, P.Y.4
-
69
-
-
33644865170
-
Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation
-
Lutgens, E., Lutgens, S. P., Faber, B. C., Heeneman, S. et al., Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation. Circulation 2006, 113, 98-107.
-
(2006)
Circulation
, vol.113
, pp. 98-107
-
-
Lutgens, E.1
Lutgens, S.P.2
Faber, B.C.3
Heeneman, S.4
-
70
-
-
33646449061
-
Inflammation and cellular immune responses in abdominal aortic aneurysms
-
Shimizu, K., Mitchell, R. N., Libby, P., Inflammation and cellular immune responses in abdominal aortic aneurysms. Arterioscler. Thromb. Vasc. Biol. 2006, 26, 987-994.
-
(2006)
Arterioscler. Thromb. Vasc. Biol.
, vol.26
, pp. 987-994
-
-
Shimizu, K.1
Mitchell, R.N.2
Libby, P.3
-
71
-
-
0032718590
-
Cystatin C deficiency in human atherosclerosis and aortic aneurysms
-
Shi, G. P., Sukhova, G. K., Grubb, A., Ducharme, A. et al., Cystatin C deficiency in human atherosclerosis and aortic aneurysms. J. Clin. Invest. 1999, 104, 1191-1197.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 1191-1197
-
-
Shi, G.P.1
Sukhova, G.K.2
Grubb, A.3
Ducharme, A.4
-
72
-
-
30044445997
-
Cathepsin L expression and regulation in human abdominal aortic aneurysm, atherosclerosis, and vascular cells
-
Liu, J., Sukhova, G. K., Yang, J. T., Sun, J. et al., Cathepsin L expression and regulation in human abdominal aortic aneurysm, atherosclerosis, and vascular cells. Atherosclerosis 2006, 184, 302-311.
-
(2006)
Atherosclerosis
, vol.184
, pp. 302-311
-
-
Liu, J.1
Sukhova, G.K.2
Yang, J.T.3
Sun, J.4
-
73
-
-
52449101897
-
Cathepsin B, K, and S are expressed in cerebral aneurysms and promote the progression of cerebral aneurysms
-
Aoki, T., Kataoka, H., Ishibashi, R., Nozaki, K., Hashimoto, N., Cathepsin B, K, and S are expressed in cerebral aneurysms and promote the progression of cerebral aneurysms. Stroke 2008, 39, 2603-2610.
-
(2008)
Stroke
, vol.39
, pp. 2603-2610
-
-
Aoki, T.1
Kataoka, H.2
Ishibashi, R.3
Nozaki, K.4
Hashimoto, N.5
-
74
-
-
48749085788
-
Superoxide-dependent cathepsin activation is associated with hypertensive myocardial remodeling and represents a target for angiotensin II type 1 receptor blocker treatment
-
Cheng, X. W., Murohara, T., Kuzuya, M., Izawa, H. et al., Superoxide-dependent cathepsin activation is associated with hypertensive myocardial remodeling and represents a target for angiotensin II type 1 receptor blocker treatment. Am. J. Pathol. 2008, 173, 358-369.
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 358-369
-
-
Cheng, X.W.1
Murohara, T.2
Kuzuya, M.3
Izawa, H.4
-
75
-
-
77955228071
-
Pharmacological inhibition of cathepsin S decreases atherosclerotic lesions in Apoe-/- mice
-
Samokhin, A. O., Lythgo, P. A., Gauthier, J. Y., Percival, M. D., Brömme, D., Pharmacological inhibition of cathepsin S decreases atherosclerotic lesions in Apoe-/- mice. J. Cardiovasc. Pharmacol. 2010, 56, 98-105.
-
(2010)
J. Cardiovasc. Pharmacol
, vol.56
, pp. 98-105
-
-
Samokhin, A.O.1
Lythgo, P.A.2
Gauthier, J.Y.3
Percival, M.D.4
Brömme, D.5
-
76
-
-
34547624086
-
Angiotensin inhibition decreases progression of advanced atherosclerosis and stabilizes established atherosclerotic plaques
-
Suganuma, E., Babaev, V. R., Motojima, M., Zuo, Y. et al., Angiotensin inhibition decreases progression of advanced atherosclerosis and stabilizes established atherosclerotic plaques. J. Am. Soc. Nephrol. 2007, 18, 2311-2319.
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 2311-2319
-
-
Suganuma, E.1
Babaev, V.R.2
Motojima, M.3
Zuo, Y.4
-
77
-
-
0019797924
-
Lysosomal cathepsin B: correlation with metastatic potential
-
Sloane, B. F., Dunn, J. R., Honn, K. V., Lysosomal cathepsin B: correlation with metastatic potential. Science 1981, 212, 1151-1153.
-
(1981)
Science
, vol.212
, pp. 1151-1153
-
-
Sloane, B.F.1
Dunn, J.R.2
Honn, K.V.3
-
78
-
-
1542604677
-
Cysteine proteases as disease markers
-
Berdowska, I., Cysteine proteases as disease markers. Clin. Chim. Acta 2004, 342, 41-69.
-
(2004)
Clin. Chim. Acta
, vol.342
, pp. 41-69
-
-
Berdowska, I.1
-
79
-
-
33749017931
-
Cysteine cathepsins: multifunctional enzymes in cancer
-
Mohamed, M. M., Sloane, B. F., Cysteine cathepsins: multifunctional enzymes in cancer. Nat. Rev. Cancer 2006, 6, 764-775.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 764-775
-
-
Mohamed, M.M.1
Sloane, B.F.2
-
80
-
-
2342603891
-
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis
-
Joyce, J. A., Baruch, A., Chehade, K., Meyer-Morse, N. et al., Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis. Cancer Cell 2004, 5, 443-453.
-
(2004)
Cancer Cell
, vol.5
, pp. 443-453
-
-
Joyce, J.A.1
Baruch, A.2
Chehade, K.3
Meyer-Morse, N.4
-
81
-
-
80052587306
-
Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment
-
Mikhaylov, G., Mikac, U., Magaeva, A. A., Itin, V. I. et al., Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment. Nat. Nanotechnol. 2011, 6, 594-602.
-
(2011)
Nat. Nanotechnol.
, vol.6
, pp. 594-602
-
-
Mikhaylov, G.1
Mikac, U.2
Magaeva, A.A.3
Itin, V.I.4
-
82
-
-
33744917827
-
Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer
-
Vasiljeva, O., Papazoglou, A., Krüger, A., Brodoefel, H. et al., Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer. Cancer Res. 2006, 66, 5242-5250.
-
(2006)
Cancer Res.
, vol.66
, pp. 5242-5250
-
-
Vasiljeva, O.1
Papazoglou, A.2
Krüger, A.3
Brodoefel, H.4
-
83
-
-
47049095033
-
Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice
-
Vasiljeva, O., Korovin, M., Gajda, M., Brodoefel, H. et al., Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice. Oncogene 2008, 27, 4191-4199.
-
(2008)
Oncogene
, vol.27
, pp. 4191-4199
-
-
Vasiljeva, O.1
Korovin, M.2
Gajda, M.3
Brodoefel, H.4
-
84
-
-
33644784910
-
Distinct roles for cysteine cathepsin genes in multistage tumorigenesis
-
Gocheva, V., Zeng, W., Ke, D., Klimstra, D. et al., Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. Genes Dev. 2006, 20, 543-556.
-
(2006)
Genes Dev.
, vol.20
, pp. 543-556
-
-
Gocheva, V.1
Zeng, W.2
Ke, D.3
Klimstra, D.4
-
85
-
-
77249161680
-
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice
-
Sevenich, L., Schurigt, U., Sachse, K., Gajda, M. et al., Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice. Proc. Natl. Acad. Sci. USA 2010, 107, 2497-2502.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 2497-2502
-
-
Sevenich, L.1
Schurigt, U.2
Sachse, K.3
Gajda, M.4
-
86
-
-
38649084746
-
Dual contrasting roles of cysteine cathepsins in cancer progression: apoptosis versus tumour invasion
-
Vasiljeva, O., Turk, B., Dual contrasting roles of cysteine cathepsins in cancer progression: apoptosis versus tumour invasion. Biochimie 2008, 90, 380-386.
-
(2008)
Biochimie
, vol.90
, pp. 380-386
-
-
Vasiljeva, O.1
Turk, B.2
-
87
-
-
0033986761
-
Causes and consequences of tumour acidity and implications for treatment
-
Stubbs, M., McSheehy, P. M., Griffiths, J. R., Bashford, C. L., Causes and consequences of tumour acidity and implications for treatment. Mol. Med. Today 2000, 6, 15-9.
-
(2000)
Mol. Med. Today
, vol.6
, pp. 15-19
-
-
Stubbs, M.1
McSheehy, P.M.2
Griffiths, J.R.3
Bashford, C.L.4
-
88
-
-
79953163995
-
Proteolytic networks in cancer
-
Mason, S. D., Joyce, J. A., Proteolytic networks in cancer. Trends Cell Biol. 2011, 21, 228-237.
-
(2011)
Trends Cell Biol.
, vol.21
, pp. 228-237
-
-
Mason, S.D.1
Joyce, J.A.2
-
89
-
-
33746354972
-
Significance of 32-kDa cathepsin L secreted from cancer cells
-
Hashimoto, Y., Kondo, C., Kojima, T., Nagata, H. et al., Significance of 32-kDa cathepsin L secreted from cancer cells. Cancer Biother. Radiopharm. 2006, 21, 217-224.
-
(2006)
Cancer Biother. Radiopharm.
, vol.21
, pp. 217-224
-
-
Hashimoto, Y.1
Kondo, C.2
Kojima, T.3
Nagata, H.4
-
90
-
-
1642535587
-
Inhibition of tumorigenicity and metastasis of human melanoma cells by anti-cathepsin L single chain variable fragment
-
Rousselet, N., Mills, L., Jean, D., Tellez, C. et al., Inhibition of tumorigenicity and metastasis of human melanoma cells by anti-cathepsin L single chain variable fragment. Cancer Res. 2004, 64, 146-151.
-
(2004)
Cancer Res.
, vol.64
, pp. 146-151
-
-
Rousselet, N.1
Mills, L.2
Jean, D.3
Tellez, C.4
-
91
-
-
0037192819
-
Analysis of a truncated form of cathepsin H in human prostate tumor cells
-
Waghray, A., Keppler, D., Sloane, B. F., Schuger, L., Chen, Y. Q., Analysis of a truncated form of cathepsin H in human prostate tumor cells. J. Biol. Chem. 2002, 277, 11533-11538.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11533-11538
-
-
Waghray, A.1
Keppler, D.2
Sloane, B.F.3
Schuger, L.4
Chen, Y.Q.5
-
92
-
-
0037969805
-
The clinical significance of cathepsin S expression in human astrocytomas
-
Flannery, T., Gibson, D., Mirakhur, M., McQuaid, S. et al., The clinical significance of cathepsin S expression in human astrocytomas. Am. J. Pathol. 2003, 163, 175-182.
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 175-182
-
-
Flannery, T.1
Gibson, D.2
Mirakhur, M.3
McQuaid, S.4
-
93
-
-
0027268709
-
Increased cell-surface urokinase in advanced ovarian cancer
-
Kobayashi, H., Moniwa, N., Sugimura, M., Shinohara, H. et al., Increased cell-surface urokinase in advanced ovarian cancer. Jpn. J. Cancer Res. 1993, 84, 633-640.
-
(1993)
Jpn. J. Cancer Res.
, vol.84
, pp. 633-640
-
-
Kobayashi, H.1
Moniwa, N.2
Sugimura, M.3
Shinohara, H.4
-
94
-
-
0041737535
-
Molecular mechanisms of glioma invasiveness: the role of proteases
-
Rao, J. S., Molecular mechanisms of glioma invasiveness: the role of proteases. Nat. Rev. Cancer 2003, 3, 489-501.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 489-501
-
-
Rao, J.S.1
-
95
-
-
0027329828
-
In vitro" study of basement membrane degradation by the cysteine proteinases, cathepsins B, B-like and L. Digestion of collagen IV, laminin, fibronectin, and release of gelatinase activities from basement membrane fibronectin
-
Guinec, N., Dalet-Fumeron, V., Pagano, M., "In vitro" study of basement membrane degradation by the cysteine proteinases, cathepsins B, B-like and L. Digestion of collagen IV, laminin, fibronectin, and release of gelatinase activities from basement membrane fibronectin. Biol. Chem. Hoppe Seyler 1993, 374, 1135-1146.
-
(1993)
Biol. Chem. Hoppe Seyler
, vol.374
, pp. 1135-1146
-
-
Guinec, N.1
Dalet-Fumeron, V.2
Pagano, M.3
-
96
-
-
0036754586
-
Degradation of extracellular matrix protein tenascin-C by cathepsin B: an interaction involved in the progression of gliomas
-
Mai, J., Sameni, M., Mikkelsen, T., Sloane, B. F., Degradation of extracellular matrix protein tenascin-C by cathepsin B: an interaction involved in the progression of gliomas. Biol. Chem. 2002, 383, 1407-1413.
-
(2002)
Biol. Chem.
, vol.383
, pp. 1407-1413
-
-
Mai, J.1
Sameni, M.2
Mikkelsen, T.3
Sloane, B.F.4
-
97
-
-
84873858791
-
Cathepsin H mediates the processing of talin and regulates migration of prostate cancer cells
-
Jevnikar, Z., Rojnik, M., Jamnik, P., Doljak, B. et al., Cathepsin H mediates the processing of talin and regulates migration of prostate cancer cells. J. Biol. Chem. 2013, 288, 2201-2209.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 2201-2209
-
-
Jevnikar, Z.1
Rojnik, M.2
Jamnik, P.3
Doljak, B.4
-
98
-
-
84872233476
-
Profilin 1 as a target for cathepsin X activity in tumor cells
-
Pečar Fonović, U., Jevnikar, Z., Rojnik, M., Doljak, B. et al., Profilin 1 as a target for cathepsin X activity in tumor cells. PLoS One 2013, 8, e53918.
-
(2013)
PLoS One
, vol.8
-
-
Pečar Fonović, U.1
Jevnikar, Z.2
Rojnik, M.3
Doljak, B.4
-
99
-
-
0035793580
-
Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route
-
Stoka, V., Turk, B., Schendel, S. L., Kim, T. H. et al., Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route. J. Biol. Chem. 2001, 276, 3149-3157.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3149-3157
-
-
Stoka, V.1
Turk, B.2
Schendel, S.L.3
Kim, T.H.4
-
100
-
-
82955189189
-
Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer
-
Shree, T., Olson, O. C., Elie, B. T., Kester, J. C. et al., Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer. Genes Dev. 2011, 25, 2465-2479.
-
(2011)
Genes Dev.
, vol.25
, pp. 2465-2479
-
-
Shree, T.1
Olson, O.C.2
Elie, B.T.3
Kester, J.C.4
-
101
-
-
37549070672
-
Cysteine cathepsin proteases as pharmacological targets in cancer
-
Palermo, C., Joyce, J. A., Cysteine cathepsin proteases as pharmacological targets in cancer. Trends. Pharmacol. Sci. 2008, 29, 22-28.
-
(2008)
Trends. Pharmacol. Sci.
, vol.29
, pp. 22-28
-
-
Palermo, C.1
Joyce, J.A.2
-
102
-
-
0003083706
-
The expression of lysosomal proteinases and their inhibitors in breast cancer: possible relationship to prognosis of the disease
-
Lah, T. T., Kos, J., Blejec, A., Frkovic-Georgio, S. et al., The expression of lysosomal proteinases and their inhibitors in breast cancer: possible relationship to prognosis of the disease. Pathol. Oncol. Res. 1997, 3, 89-99.
-
(1997)
Pathol. Oncol. Res.
, vol.3
, pp. 89-99
-
-
Lah, T.T.1
Kos, J.2
Blejec, A.3
Frkovic-Georgio, S.4
-
103
-
-
0031887693
-
Prognostic significance of cathepsins B and L in primary human breast cancer
-
Foekens, J. A., Kos, J., Peters, H. A., Krasovec, M. et al., Prognostic significance of cathepsins B and L in primary human breast cancer. J. Clin. Oncol. 1998, 16, 1013-1021.
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 1013-1021
-
-
Foekens, J.A.1
Kos, J.2
Peters, H.A.3
Krasovec, M.4
-
104
-
-
78650727555
-
Cathepsin B: a potential prognostic marker for inflammatory breast cancer
-
Nouh, M. A., Mohamed, M. M., El-Shinawi, M., Shaalan, M. A. et al., Cathepsin B: a potential prognostic marker for inflammatory breast cancer. J. Transl. Med. 2011, 9, 1.
-
(2011)
J. Transl. Med.
, vol.9
, pp. 1
-
-
Nouh, M.A.1
Mohamed, M.M.2
El-Shinawi, M.3
Shaalan, M.A.4
-
105
-
-
0034128337
-
Cysteine proteinases and their inhibitors in extracellular fluids: markers for diagnosis and prognosis in cancer
-
Kos, J., Werle, B., Lah, T., Brunner, N., Cysteine proteinases and their inhibitors in extracellular fluids: markers for diagnosis and prognosis in cancer. Int. J. Biol. Markers 2000, 15, 84-89.
-
(2000)
Int. J. Biol. Markers
, vol.15
, pp. 84-89
-
-
Kos, J.1
Werle, B.2
Lah, T.3
Brunner, N.4
-
106
-
-
80054723111
-
Clinical value of combined detection of serum matrix metalloproteinase-9, heparanase, and cathepsin for determining ovarian cancer invasion and metastasis
-
Zhang, W., Yang, H. C., Wang, Q., Yang, Z. J. et al., Clinical value of combined detection of serum matrix metalloproteinase-9, heparanase, and cathepsin for determining ovarian cancer invasion and metastasis. Anticancer Res. 2011, 31, 3423-3428.
-
(2011)
Anticancer Res.
, vol.31
, pp. 3423-3428
-
-
Zhang, W.1
Yang, H.C.2
Wang, Q.3
Yang, Z.J.4
-
107
-
-
0035914268
-
Cathepsin S in tumours, regional lymph nodes and sera of patients with lung cancer: relation to prognosis
-
Kos, J., Sekirnik, A., Kopitar, G., Cimerman, N. et al., Cathepsin S in tumours, regional lymph nodes and sera of patients with lung cancer: relation to prognosis. Br. J. Cancer 2001, 85, 1193-1200.
-
(2001)
Br. J. Cancer
, vol.85
, pp. 1193-1200
-
-
Kos, J.1
Sekirnik, A.2
Kopitar, G.3
Cimerman, N.4
-
108
-
-
78549293229
-
Cathepsins B and L in peripheral blood mononuclear cells of pediatric acute myeloid leukemia: potential poor prognostic markers
-
Jain, M., Bakhshi, S., Shukla, A. A., Chauhan, S. S., Cathepsins B and L in peripheral blood mononuclear cells of pediatric acute myeloid leukemia: potential poor prognostic markers. Ann. Hematol. 2010, 89, 1223-1232.
-
(2010)
Ann. Hematol.
, vol.89
, pp. 1223-1232
-
-
Jain, M.1
Bakhshi, S.2
Shukla, A.A.3
Chauhan, S.S.4
-
109
-
-
12344325808
-
Serum cathepsin H as a potential prognostic marker in patients with colorectal cancer
-
Schweiger, A., Christensen, I. J., Nielsen, H. J., Sørensen, S. et al., Serum cathepsin H as a potential prognostic marker in patients with colorectal cancer. Int. J. Biol. Markers 2004, 19, 289-294.
-
(2004)
Int. J. Biol. Markers
, vol.19
, pp. 289-294
-
-
Schweiger, A.1
Christensen, I.J.2
Nielsen, H.J.3
Sørensen, S.4
-
110
-
-
84867296995
-
Cathepsin X in serum from patients with colorectal cancer: relation to prognosis
-
Vizin, T., Christensen, I. J., Nielsen, H. J., Kos, J., Cathepsin X in serum from patients with colorectal cancer: relation to prognosis. Radiol. Oncol. 2012, 46, 207-212.
-
(2012)
Radiol. Oncol
, vol.46
, pp. 207-212
-
-
Vizin, T.1
Christensen, I.J.2
Nielsen, H.J.3
Kos, J.4
-
111
-
-
33646518541
-
Increased serum cathepsin S in patients with atherosclerosis and diabetes
-
Liu, J., Ma, L., Yang, J., Ren, A. et al., Increased serum cathepsin S in patients with atherosclerosis and diabetes. Atherosclerosis 2006, 186, 411-419.
-
(2006)
Atherosclerosis
, vol.186
, pp. 411-419
-
-
Liu, J.1
Ma, L.2
Yang, J.3
Ren, A.4
-
112
-
-
59049103199
-
Usefulness of serum cathepsin L as an independent biomarker in patients with coronary heart disease
-
Liu, Y., Li, X., Peng, D., Tan, Z. et al., Usefulness of serum cathepsin L as an independent biomarker in patients with coronary heart disease. Am. J. Cardiol. 2009, 103, 476-481.
-
(2009)
Am. J. Cardiol.
, vol.103
, pp. 476-481
-
-
Liu, Y.1
Li, X.2
Peng, D.3
Tan, Z.4
-
113
-
-
66249143728
-
Cystatin C and NT-proBNP, a powerful combination of biomarkers for predicting cardiovascular mortality in elderly patients with heart failure: results from a 10-year study in primary care
-
Alehagen, U., Dahlström, U., Lindahl, T. L., Cystatin C and NT-proBNP, a powerful combination of biomarkers for predicting cardiovascular mortality in elderly patients with heart failure: results from a 10-year study in primary care. Eur. J. Heart Fail. 2009, 11, 354-360.
-
(2009)
Eur. J. Heart Fail
, vol.11
, pp. 354-360
-
-
Alehagen, U.1
Dahlström, U.2
Lindahl, T.L.3
-
114
-
-
84881222169
-
Identification, prioritization, and evaluation of glycoproteins for aggressive prostate cancer using quantitative glycoproteomics and antibody-based assays on tissue specimens
-
Chen, J., Xi, J., Tian, Y., Bova, G. S., Zhang, H., Identification, prioritization, and evaluation of glycoproteins for aggressive prostate cancer using quantitative glycoproteomics and antibody-based assays on tissue specimens. Proteomics 2013, 13, 2268-2277.
-
(2013)
Proteomics
, vol.13
, pp. 2268-2277
-
-
Chen, J.1
Xi, J.2
Tian, Y.3
Bova, G.S.4
Zhang, H.5
-
115
-
-
33846167705
-
Activity based probes for proteases: applications to biomarker discovery, molecular imaging and drug screening
-
Fonović, M., Bogyo, M., Activity based probes for proteases: applications to biomarker discovery, molecular imaging and drug screening. Curr. Pharm. Des. 2007, 13, 253-261.
-
(2007)
Curr. Pharm. Des.
, vol.13
, pp. 253-261
-
-
Fonović, M.1
Bogyo, M.2
-
116
-
-
84862873324
-
Activity-based probes for the study of proteases: recent advances and developments
-
Serim, S., Haedke, U., Verhelst, S. H., Activity-based probes for the study of proteases: recent advances and developments. Chem. Med. Chem. 2012, 7, 1146-1159.
-
(2012)
Chem. Med. Chem.
, vol.7
, pp. 1146-1159
-
-
Serim, S.1
Haedke, U.2
Verhelst, S.H.3
-
117
-
-
38049057786
-
Selective activity-based probes for cysteine cathepsins
-
Watzke, A., Kosec, G., Kindermann, M., Jeske, V. et al., Selective activity-based probes for cysteine cathepsins. Angew Chem. Int. Ed. Engl. 2008, 47, 406-409.
-
(2008)
Angew Chem. Int. Ed. Engl.
, vol.47
, pp. 406-409
-
-
Watzke, A.1
Kosec, G.2
Kindermann, M.3
Jeske, V.4
-
118
-
-
43749107913
-
Application of activity-based probes to the study of enzymes involved in cancer progression
-
Paulick, M. G., Bogyo, M., Application of activity-based probes to the study of enzymes involved in cancer progression. Curr. Opin. Genet. Dev. 2008, 18, 97-106.
-
(2008)
Curr. Opin. Genet. Dev.
, vol.18
, pp. 97-106
-
-
Paulick, M.G.1
Bogyo, M.2
-
119
-
-
79551503110
-
Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation
-
Caglič, D., Globisch, A., Kindermann, M., Lim, N. H. et al., Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation. Bioorg. Med. Chem. 2011, 19, 1055-1061.
-
(2011)
Bioorg. Med. Chem.
, vol.19
, pp. 1055-1061
-
-
Caglič, D.1
Globisch, A.2
Kindermann, M.3
Lim, N.H.4
-
120
-
-
33846821908
-
Proteomic discovery of protease substrates
-
Schilling, O., Overall, C. M., Proteomic discovery of protease substrates. Curr. Opin. Chem. Biol. 2007, 11, 36-45.
-
(2007)
Curr. Opin. Chem. Biol.
, vol.11
, pp. 36-45
-
-
Schilling, O.1
Overall, C.M.2
-
121
-
-
84858969517
-
Functional protease profiling for diagnosis of malignant disease
-
Findeisen, P., Neumaier, M., Functional protease profiling for diagnosis of malignant disease. Proteomics Clin. Appl. 2012, 6, 60-78.
-
(2012)
Proteomics Clin. Appl.
, vol.6
, pp. 60-78
-
-
Findeisen, P.1
Neumaier, M.2
-
122
-
-
27144473929
-
Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis
-
Van Damme, P., Martens, L., Van Damme, J., Hugelier, K. et al., Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis. Nat. Methods 2005, 2, 771-777.
-
(2005)
Nat. Methods
, vol.2
, pp. 771-777
-
-
Van Damme, P.1
Martens, L.2
Van Damme, J.3
Hugelier, K.4
-
123
-
-
33847276695
-
In search of partners: linking extracellular proteases to substrates
-
Overall, C. M., Blobel, C. P., In search of partners: linking extracellular proteases to substrates. Nat. Rev. Mol. Cell Biol. 2007, 8, 245-257.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 245-257
-
-
Overall, C.M.1
Blobel, C.P.2
-
124
-
-
0038333588
-
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides
-
Gevaert, K., Goethals, M., Martens, L., Van Damme, J. et al., Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. Nat. Biotechnol. 2003, 21, 566-569.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 566-569
-
-
Gevaert, K.1
Goethals, M.2
Martens, L.3
Van Damme, J.4
-
125
-
-
82755164012
-
Proteomic identification of protease cleavage sites characterizes prime and non-prime specificity of cysteine cathepsins B, L, and S
-
Biniossek, M. L., Nägler, D. K., Becker-Pauly, C., Schilling, O., Proteomic identification of protease cleavage sites characterizes prime and non-prime specificity of cysteine cathepsins B, L, and S. J. Proteome Res. 2011, 10, 5363-5373.
-
(2011)
J. Proteome Res.
, vol.10
, pp. 5363-5373
-
-
Biniossek, M.L.1
Nägler, D.K.2
Becker-Pauly, C.3
Schilling, O.4
-
126
-
-
84893850175
-
Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis
-
Tholen, S., Biniossek, M. L., Gansz, M., Ahrens, T. D. et al., Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis. Cell Mol. Life Sci. 2013, 71, 899-916.
-
(2013)
Cell Mol. Life Sci.
, vol.71
, pp. 899-916
-
-
Tholen, S.1
Biniossek, M.L.2
Gansz, M.3
Ahrens, T.D.4
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