IRF7-dependent type i interferon production induces lethal immune-mediated disease in STAT1 knockout mice infected with lymphocytic choriomeningitis virus

Journal of Virology

Volumn 88, Issue 13, 2014, Pages 7578-7588

  Li, Wen ^a   Hofer, Markus J ^a   Jung, So Ri ^a   Lim, Sue Ling ^a   Campbell, Iain L ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 7; INTERFERON REGULATORY FACTOR 9; MONOCYTE CHEMOTACTIC PROTEIN 1; STAT1 PROTEIN; STAT2 PROTEIN; INTERFERON; IRF9 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE; GENE EXPRESSION; IFN I GENE; IMMUNE RESPONSE; IMMUNOPATHOLOGY; LIVER; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SIGNAL TRANSDUCTION; SPLEEN; SURVIVAL; TRANSCRIPTION REGULATION; VIRUS REPLICATION; VIRUS TRANSMISSION; ANIMAL; C57BL MOUSE; CD4+ T LYMPHOCYTE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOLOGY; KNOCKOUT MOUSE; LETHAL GENE; MALE; METABOLISM; MORTALITY; PHYSIOLOGY; SURVIVAL RATE; VIROLOGY;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENES, LETHAL; INTERFERON TYPE I; INTERFERON-STIMULATED GENE FACTOR 3, GAMMA SUBUNIT; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; STAT1 TRANSCRIPTION FACTOR; SURVIVAL RATE;

EID: 84901989737     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03117-13     Document Type: Article

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