-
1
-
-
84879009206
-
Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction?
-
Malik, A.N. et al. (2013) Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction? Mitochondrion, 13, 481-492.
-
(2013)
Mitochondrion
, vol.13
, pp. 481-492
-
-
Malik, A.N.1
-
2
-
-
0034333230
-
The inheritance of mitochondrial DNA heteroplasmy: random drift, selection or both?
-
Chinnery, P.F. et al. (2000) The inheritance of mitochondrial DNA heteroplasmy: random drift, selection or both? Trends Genet., 16, 500-505.
-
(2000)
Trends Genet.
, vol.16
, pp. 500-505
-
-
Chinnery, P.F.1
-
3
-
-
41149143265
-
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma
-
Gasparre, G. et al. (2008) Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma. Hum. Mol. Genet., 17, 986-995.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 986-995
-
-
Gasparre, G.1
-
4
-
-
84859911664
-
Physiology and pathophysiology of mitochondrial DNA
-
Li, H. et al. (2012) Physiology and pathophysiology of mitochondrial DNA. Adv. Exp. Med. Biol., 942, 39-51.
-
(2012)
Adv. Exp. Med. Biol.
, vol.942
, pp. 39-51
-
-
Li, H.1
-
5
-
-
85006768050
-
The metabolism of tumors in the body
-
Warburg, O. et al. (1927) The metabolism of tumors in the body. J. Gen. Physiol., 8, 519-530.
-
(1927)
J. Gen. Physiol.
, vol.8
, pp. 519-530
-
-
Warburg, O.1
-
6
-
-
79959757175
-
Accumulation of mutations over the entire mitochondrial genome of breast cancer cells obtained by tissue microdissection
-
Fendt, L. et al. (2011) Accumulation of mutations over the entire mitochondrial genome of breast cancer cells obtained by tissue microdissection. Breast Cancer Res. Treat., 128, 327-336.
-
(2011)
Breast Cancer Res. Treat.
, vol.128
, pp. 327-336
-
-
Fendt, L.1
-
7
-
-
0031736203
-
Somatic mutations of the mitochondrial genome in human colorectal tumours
-
Polyak, K. et al. (1998) Somatic mutations of the mitochondrial genome in human colorectal tumours. Nat. Genet., 20, 291-293.
-
(1998)
Nat. Genet.
, vol.20
, pp. 291-293
-
-
Polyak, K.1
-
8
-
-
33646559185
-
Significance of somatic mutations and content alteration of mitochondrial DNA in esophageal cancer
-
Tan, D.J. et al. (2006) Significance of somatic mutations and content alteration of mitochondrial DNA in esophageal cancer. BMC Cancer, 6, 93.
-
(2006)
BMC Cancer
, vol.6
, pp. 93
-
-
Tan, D.J.1
-
9
-
-
0035866352
-
Detection of mitochondrial DNA mutations in pancreatic cancer offers a "mass"-ive advantage over detection of nuclear DNA mutations
-
Jones, J.B. et al. (2001) Detection of mitochondrial DNA mutations in pancreatic cancer offers a "mass"-ive advantage over detection of nuclear DNA mutations. Cancer Res., 61, 1299-1304.
-
(2001)
Cancer Res.
, vol.61
, pp. 1299-1304
-
-
Jones, J.B.1
-
10
-
-
78649794554
-
Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients
-
Kloss-Brandstätter, A. et al. (2010) Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients. Am. J. Hum. Genet., 87, 802-812.
-
(2010)
Am. J. Hum. Genet.
, vol.87
, pp. 802-812
-
-
Kloss-Brandstätter, A.1
-
11
-
-
63849153962
-
MtDNA mutation pattern in tumors and human evolution are shaped by similar selective constraints
-
Zhidkov, I. et al. (2009) MtDNA mutation pattern in tumors and human evolution are shaped by similar selective constraints. Genome Res., 19, 576-580.
-
(2009)
Genome Res.
, vol.19
, pp. 576-580
-
-
Zhidkov, I.1
-
12
-
-
2942531063
-
Mitochondrial defects in cancer
-
Carew, J.S. et al. (2002) Mitochondrial defects in cancer. Mol. Cancer, 1, 9.
-
(2002)
Mol. Cancer
, vol.1
, pp. 9
-
-
Carew, J.S.1
-
13
-
-
84859886931
-
Mitochondria and reactive oxygen species. Which role in physiology and pathology?
-
Lenaz, G. (2012) Mitochondria and reactive oxygen species. Which role in physiology and pathology? Adv. Exp. Med. Biol., 942, 93-136.
-
(2012)
Adv. Exp. Med. Biol.
, vol.942
, pp. 93-136
-
-
Lenaz, G.1
-
14
-
-
60249089837
-
Mitochondria as targets for cancer chemotherapy
-
Gogvadze, V. et al. (2009) Mitochondria as targets for cancer chemotherapy. Semin. Cancer Biol., 19, 57-66.
-
(2009)
Semin. Cancer Biol.
, vol.19
, pp. 57-66
-
-
Gogvadze, V.1
-
15
-
-
67650071137
-
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
-
Trachootham, D. et al. (2009) Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat. Rev. Drug Discov., 8, 579-591.
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 579-591
-
-
Trachootham, D.1
-
16
-
-
0034972303
-
High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection
-
Zhidkov, I. et al. (2001) High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection. Nat. Genet., 2, 147-150.
-
(2001)
Nat. Genet.
, vol.2
, pp. 147-150
-
-
Zhidkov, I.1
-
17
-
-
84865560511
-
Spectrum of somatic mitochondrial mutations in five cancers
-
Larman, T.C. et al. (2012) Spectrum of somatic mitochondrial mutations in five cancers. Proc. Natl Acad. Sci. USA, 109, 14087-14091.
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 14087-14091
-
-
Larman, T.C.1
-
18
-
-
84855792427
-
Cancer statistics, 2012
-
Siegel, R. et al. (2012) Cancer statistics, 2012. CA. Cancer J. Clin., 62, 10-29.
-
(2012)
CA. Cancer J. Clin.
, vol.62
, pp. 10-29
-
-
Siegel, R.1
-
19
-
-
77952507615
-
Breast cancer in the personal genomics era
-
Ellsworth, R.E. et al. (2010) Breast cancer in the personal genomics era. Curr. Genomics, 11, 146-161.
-
(2010)
Curr. Genomics
, vol.11
, pp. 146-161
-
-
Ellsworth, R.E.1
-
20
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
The Cancer Genome Atlas Research Network.
-
The Cancer Genome Atlas Research Network. (2012) Comprehensive molecular portraits of human breast tumours. Nature, 490, 61-70.
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
-
21
-
-
84864917026
-
Identification of high-confidence somatic mutations in whole genome sequence of formalin-fixed breast cancer specimens
-
Yost, S.E. et al. (2012) Identification of high-confidence somatic mutations in whole genome sequence of formalin-fixed breast cancer specimens. Nucleic Acids Res., 40, e107.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Yost, S.E.1
-
22
-
-
68149137896
-
Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis
-
Lu, J. et al. (2009) Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis. Cell Res., 19, 802-815.
-
(2009)
Cell Res.
, vol.19
, pp. 802-815
-
-
Lu, J.1
-
23
-
-
84882731702
-
MitoSeek: extracting mitochondria information and performing high-throughput mitochondria sequencing analysis
-
Guo, Y. et al. (2013) MitoSeek: extracting mitochondria information and performing high-throughput mitochondria sequencing analysis. Bioinformatics, 29, 1210-1211.
-
(2013)
Bioinformatics
, vol.29
, pp. 1210-1211
-
-
Guo, Y.1
-
24
-
-
84861988033
-
Mitochondrial genomes gleaned from human whole-exome sequencing
-
Picardi, E. et al. (2012) Mitochondrial genomes gleaned from human whole-exome sequencing. Nat. Methods, 9, 523-524.
-
(2012)
Nat. Methods
, vol.9
, pp. 523-524
-
-
Picardi, E.1
-
25
-
-
68549104404
-
The Sequence Alignment/Map format and SAMtools
-
Li, H. et al. (2009) The Sequence Alignment/Map format and SAMtools. Bioinformatics, 25, 2078-2079.
-
(2009)
Bioinformatics
, vol.25
, pp. 2078-2079
-
-
Li, H.1
-
26
-
-
0032868141
-
Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA
-
Andrews, R.M. et al. (1999) Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA. Nat. Genet., 23, 147.
-
(1999)
Nat. Genet.
, vol.23
, pp. 147
-
-
Andrews, R.M.1
-
27
-
-
84859210032
-
Fast gapped-read alignment with Bowtie 2
-
Langmead, B. et al. (2012) Fast gapped-read alignment with Bowtie 2. Nat. Methods, 9, 357-359.
-
(2012)
Nat. Methods
, vol.9
, pp. 357-359
-
-
Langmead, B.1
-
28
-
-
79955483667
-
A framework for variation discovery and genotyping using next-generation DNA sequencing data
-
DePristo, M.A. et al. (2011) A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat. Genet., 43, 491-498.
-
(2011)
Nat. Genet.
, vol.43
, pp. 491-498
-
-
DePristo, M.A.1
-
29
-
-
78651271733
-
Integrative genomics viewer
-
Robinson, J.T. et al. (2011) Integrative genomics viewer. Nat. Biotechnol., 29, 24-26.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 24-26
-
-
Robinson, J.T.1
-
30
-
-
84862506964
-
A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3
-
Cingolani, P. et al. (2012) A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3. Fly (Austin), 6, 80-92.
-
(2012)
Fly (Austin)
, vol.6
, pp. 80-92
-
-
Cingolani, P.1
-
31
-
-
33846094306
-
An enhanced MITOMAP with a global mtDNA mutational phylogeny
-
Ruiz-Pesini, E. et al. (2007) An enhanced MITOMAP with a global mtDNA mutational phylogeny. Nucleic Acids Res., 35, D823-D828.
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
Ruiz-Pesini, E.1
-
32
-
-
34447525139
-
Mamit-tRNA, a database of mammalian mitochondrial tRNA primary and secondary structures
-
Pütz, J. et al. (2007) Mamit-tRNA, a database of mammalian mitochondrial tRNA primary and secondary structures. RNA, 13, 1184-1190.
-
(2007)
RNA
, vol.13
, pp. 1184-1190
-
-
Pütz, J.1
-
33
-
-
23144460836
-
The tRNAscan-SE, snoscan and snoGPS web servers for the detection of tRNAs and snoRNAs
-
Schattner, P. et al. (2005) The tRNAscan-SE, snoscan and snoGPS web servers for the detection of tRNAs and snoRNAs. Nucleic Acids Res., 33, W686-W689.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Schattner, P.1
-
34
-
-
41149089793
-
SeqinR 1.0-2: a contributed package to the R project for statistical computing devoted to biological sequences retrieval and analysis. Structural approaches to sequence evolution: molecules, networks, populations
-
In Bastolla, U. et al. (ed.), Springer-Verlag, New York
-
Charif, D. et al. (2007) SeqinR 1.0-2: a contributed package to the R project for statistical computing devoted to biological sequences retrieval and analysis. Structural approaches to sequence evolution: molecules, networks, populations. In Bastolla, U. et al. (ed.) Biological and Medical Physics, Biomedical Engineering. Springer-Verlag, New York, pp. 207-232.
-
(2007)
Biological and Medical Physics, Biomedical Engineering
, pp. 207-232
-
-
Charif, D.1
-
35
-
-
36448991500
-
Clustal W and Clustal X version 2.0
-
Larkin, M.A. et al. (2007) Clustal W and Clustal X version 2.0. Bioinformatics, 23, 2947-2948.
-
(2007)
Bioinformatics
, vol.23
, pp. 2947-2948
-
-
Larkin, M.A.1
-
36
-
-
84863304598
-
-
R Development Core Team, R Foundation for Statistical Computing, Vienna, Austria
-
R Development Core Team. (2011) R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria.
-
(2011)
R: a language and environment for statistical computing
-
-
-
37
-
-
84871565767
-
Universal heteroplasmy of human mitochondrial DNA
-
Payne, B.A. et al. (2013) Universal heteroplasmy of human mitochondrial DNA. Hum. Mol. Genet., 22, 384-390.
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 384-390
-
-
Payne, B.A.1
-
38
-
-
79954429620
-
Evaluating mitochondrial DNA in patients with breast cancer and benign breast disease
-
Shen, L. et al. (2011) Evaluating mitochondrial DNA in patients with breast cancer and benign breast disease. J. Cancer Res. Clin. Oncol., 137, 669-675.
-
(2011)
J. Cancer Res. Clin. Oncol.
, vol.137
, pp. 669-675
-
-
Shen, L.1
-
39
-
-
0033804530
-
Hypervariable sites in the mtDNA control region are mutational hotspots
-
Stoneking, M. (2000) Hypervariable sites in the mtDNA control region are mutational hotspots. Am. J. Hum. Genet., 67, 1029-1032.
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 1029-1032
-
-
Stoneking, M.1
-
40
-
-
20444455342
-
The increase of mitochondrial DNA content in endometrial adenocarcinoma cells: a quantitative study using laser-captured microdissected tissues
-
Wang, Y. et al. (2005) The increase of mitochondrial DNA content in endometrial adenocarcinoma cells: a quantitative study using laser-captured microdissected tissues. Gynecol. Oncol., 98, 104-110.
-
(2005)
Gynecol. Oncol.
, vol.98
, pp. 104-110
-
-
Wang, Y.1
-
41
-
-
68149147567
-
Mitochondrial DNA content in paired normal and cancerous breast tissue samples from patients with breast cancer
-
Fan, A.X. et al. (2009) Mitochondrial DNA content in paired normal and cancerous breast tissue samples from patients with breast cancer. J. Cancer Res. Clin. Oncol., 135, 983-989.
-
(2009)
J. Cancer Res. Clin. Oncol.
, vol.135
, pp. 983-989
-
-
Fan, A.X.1
-
42
-
-
79951970227
-
CNVnator: an approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing
-
Abyzov, A. et al. (2011) CNVnator: an approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing. Genome Res., 21, 974-984.
-
(2011)
Genome Res.
, vol.21
, pp. 974-984
-
-
Abyzov, A.1
-
43
-
-
58149218240
-
High-resolution mapping of copy-number alterations with massively parallel sequencing
-
Chiang, D.Y. et al. (2009) High-resolution mapping of copy-number alterations with massively parallel sequencing. Nat. Methods, 6, 99-103.
-
(2009)
Nat. Methods
, vol.6
, pp. 99-103
-
-
Chiang, D.Y.1
-
44
-
-
0025270946
-
Distinct genomic copy number in mitochondria of different mammalian organs
-
Veltri, K.L. et al. (1990) Distinct genomic copy number in mitochondria of different mammalian organs. J. Cell. Physiol., 143, 160-164.
-
(1990)
J. Cell. Physiol.
, vol.143
, pp. 160-164
-
-
Veltri, K.L.1
-
45
-
-
79953780968
-
How mutations in tRNA distant from the anticodon affect the fidelity of decoding
-
Schmeing, T.M. et al. (2011) How mutations in tRNA distant from the anticodon affect the fidelity of decoding. Nat. Struct. Mol. Biol., 18, 432-436.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 432-436
-
-
Schmeing, T.M.1
-
46
-
-
84902009837
-
Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment
-
in press
-
Iommarini, L. et al. (2013) Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment. Hum. Mol. Genet., in press.
-
(2013)
Hum. Mol. Genet.
-
-
Iommarini, L.1
-
47
-
-
42249099171
-
Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma
-
Mayr, J.A. et al. (2008) Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma. Clin. Cancer Res., 14, 2270-2275.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 2270-2275
-
-
Mayr, J.A.1
-
48
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Alexandrov, L.B. et al. (2013) Signatures of mutational processes in human cancer. Nature, 500, 415-421.
-
(2013)
Nature
, vol.500
, pp. 415-421
-
-
Alexandrov, L.B.1
-
49
-
-
84880507665
-
Mutational heterogeneity in cancer and the search for new cancer-associated genes
-
Lawrence, M.S. et al. (2013) Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature, 499, 214-218.
-
(2013)
Nature
, vol.499
, pp. 214-218
-
-
Lawrence, M.S.1
-
50
-
-
84856717197
-
Prognostic implications and molecular associations of NADH dehydrogenase subunit 4 (ND4) mutations in acute myeloid leukemia
-
Damm, F. et al. (2012) Prognostic implications and molecular associations of NADH dehydrogenase subunit 4 (ND4) mutations in acute myeloid leukemia. Leukemia, 26, 289-295.
-
(2012)
Leukemia
, vol.26
, pp. 289-295
-
-
Damm, F.1
|