Substance abuse, memory, and post-traumatic stress disorder

Neurobiology of Learning and Memory

Volumn 112, Issue , 2014, Pages 87-100

  Tipps, Megan E ^a   Raybuck, Jonathan D ^a   Lattal, K Matthew ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Amygdala; Consolidation; Extinction; Hippocampus; Prefrontal cortex; Reconsolidation; Stress

Indexed keywords

3 METHYL 5 (1 METHYL 2 PYRROLIDINYL)ISOXAZOLE; ALCOHOL; COCAINE; DOPAMINE; NICOTINE; NICOTINIC RECEPTOR; VARENICLINE;

ALCOHOL CONSUMPTION; ALCOHOL INTOXICATION; ALCOHOL WITHDRAWAL; ANXIETY; BRAIN FUNCTION; CELL METABOLISM; COGNITION; COGNITIVE DEFECT; COMORBIDITY; CONDITIONING; DISEASE ASSOCIATION; DISEASE DURATION; DRUG DEPENDENCE; EXECUTIVE FUNCTION; HUMAN; LATENT INHIBITION; LEARNING DISORDER; LONG TERM POTENTIATION; MEMORY; MEMORY DISORDER; MOLECULAR MECHANICS; NONHUMAN; POSTTRAUMATIC STRESS DISORDER; REVIEW; RISK FACTOR; SMOKING; SMOKING CESSATION; SUBSTANCE ABUSE; TOBACCO DEPENDENCE; VERBAL MEMORY; WORKING MEMORY; ADDICTION; ANIMAL; DRUG EFFECTS; FEAR; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; COCAINE; CONDITIONING (PSYCHOLOGY); ETHANOL; FEAR; HUMANS; MEMORY; NICOTINE; STRESS DISORDERS, POST-TRAUMATIC; SUBSTANCE-RELATED DISORDERS;

EID: 84901949625     PISSN: 10747427     EISSN: 10959564     Source Type: Journal    
DOI: 10.1016/j.nlm.2013.12.002     Document Type: Review

References (202)

1. Akirav I., Maroun M. The role of the medial prefrontal cortex-amygdala circuit in stress effects on the extinction of fear. Neural Plasticity 2007, 2007:30873.
2. Alexandrov Yu I., Grinchenko Yu V., Laukka S., Jarvilehto T., Maz V.N., Korpusova A.V. Effect of ethanol on hippocampal neurons depends on their behavioural specialization. Acta Physiologica Scandinavica 1993, 149:105-115.
3. Alijan-pour J., Abrari K., Bluki T.L., Ghorbanian M.T., Goudarzi I., Salmani M.E., et al. Acute ethanol administration affects memory reactivation: A look at the neuronal density and apoptosis in the rat hippocampus. Pharmacology, Biochemistry and Behavior 2012, 102:321-328.
4. Almada R.C., Albrechet-Souza L., Brandao M.L. Further evidence for involvement of the dorsal hippocampus serotonergic and gamma-aminobutyric acid (GABA)ergic pathways in the expression of contextual fear conditioning in rats. Journal of Psychopharmacology 2013.
5. Aouizerate B., Ho A., Schluger J.H., Perret G., Borg L., Le Moal M., et al. Glucocorticoid negative feedback in methadone-maintained former heroin addicts with ongoing cocaine dependence: Dose-response to dexamethasone suppression. Addiction Biology 2006, 11:84-96.
6. Ardila A., Rosselli M., Strumwasser S. Neuropsychological deficits in chronic cocaine abusers. International Journal of Neuroscience 1991, 57:73-79.
7. Aston-Jones G., Harris G.C. Brain substrates for increased drug seeking during protracted withdrawal. Neuropharmacology 2004, 47(Suppl 1):167-179.
8. Bardo M.T., Bevins R.A. Conditioned place preference: What does it add to our preclinical understanding of drug reward?. Psychopharmacology (Berl) 2000, 153:31-43.
9. Barik J., Wonnacott S. Molecular and cellular mechanisms of action of nicotine in the CNS. Handbook of Experimental Pharmacology 2009, 173-207.
10. Barrenha G.D., Coon L.E., Chester J.A. Effects of alcohol on the acquisition and expression of fear-potentiated startle in mouse lines selectively bred for high and low alcohol preference. Psychopharmacology (Berl) 2011, 218:191-201.
11. Becker H.C., Diaz-Granados J.L., Hale R.L. Exacerbation of ethanol withdrawal seizures in mice with a history of multiple withdrawal experience. Pharmacology, Biochemistry and Behavior 1997, 57:179-183.
12. Becker H.C., Diaz-Granados J.L., Weathersby R.T. Repeated ethanol withdrawal experience increases the severity and duration of subsequent withdrawal seizures in mice. Alcohol 1997, 14:319-326.
13. Becker H.C., Hale R.L. Repeated episodes of ethanol withdrawal potentiate the severity of subsequent withdrawal seizures: An animal model of alcohol withdrawal "kindling". Alcoholism, Clinical and Experimental Research 1993, 17:94-98.
14. Beckham J.C., Dennis M.F., McClernon F.J., Mozley S.L., Collie C.F., Vrana S.R. The effects of cigarette smoking on script-driven imagery in smokers with and without posttraumatic stress disorder. Addictive Behaviors 2007, 32:2900-2915.
15. Benowitz N.L. Cigarette smoking and nicotine addiction. The Medical Clinics of North America 1992, 76:415-437.
16. Bertotto M.E., Bustos S.G., Molina V.A., Martijena I.D. Influence of ethanol withdrawal on fear memory: Effect of D-cycloserine. Neuroscience 2006, 142:979-990.
17. Blanchard D.C., Blanchard R.J. Cocaine potentiates defensive behaviors related to fear and anxiety. Neuroscience and Biobehavioral Reviews 1999, 23:981-991.
18. Blanco C., Xu Y., Brady K., Perez-Fuentes G., Okuda M., Wang S. Comorbidity of posttraumatic stress disorder with alcohol dependence among US adults: Results from national epidemiological survey on alcohol and related conditions. Drug and Alcohol Dependence 2013.
19. Bliss T.V., Collingridge G.L. Expression of NMDA receptor-dependent LTP in the hippocampus: Bridging the divide. Molecular Brain 2013, 6:5.
20. Borlikova G.G., Elbers N.A., Stephens D.N. Repeated withdrawal from ethanol spares contextual fear conditioning and spatial learning but impairs negative patterning and induces over-responding: Evidence for effect on frontal cortical but not hippocampal function?. The European Journal of Neuroscience 2006, 24:205-216.
21. Borowski T.B., Kokkinidis L. Cocaine preexposure sensitizes conditioned fear in a potentiated acoustic startle paradigm. Pharmacology, Biochemistry and Behavior 1994, 49:935-942.
22. Borowski T.B., Kokkinidis L. The effects of cocaine, amphetamine, and the dopamine D1 receptor agonist SKF 38393 on fear extinction as measured with potentiated startle: Implications for psychomotor stimulant psychosis. Behavioral Neuroscience 1998, 112:952-965.
23. Brady K.T., Lydiard R.B. The association of alcoholism and anxiety. The Psychiatric Quarterly 1993, 64:135-149.
24. Brady K.T., Sinha R. Co-occurring mental and substance use disorders: The neurobiological effects of chronic stress. The American Journal of Psychiatry 2005, 162:1483-1493.
25. Bratt A.M., Kelley S.P., Knowles J.P., Barrett J., Davis K., Davis M., et al. Long term modulation of the HPA axis by the hippocampus. Behavioral, biochemical and immunological endpoints in rats exposed to chronic mild stress. Psychoneuroendocrinology 2001, 26:121-145.
26. Breese G.R., Sinha R., Heilig M. Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. Pharmacology & Therapeutics 2011, 129:149-171.
27. Bremner J.D., Randall P., Scott T.M., Bronen R.A., Seibyl J.P., Southwick S.M., et al. MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. The American Journal of Psychiatry 1995, 152:973-981.
28. Bremner J.D., Southwick S.M., Darnell A., Charney D.S. Chronic PTSD in Vietnam combat veterans: Course of illness and substance abuse. The American Journal of Psychiatry 1996, 153:369-375.
29. Breslau N., Davis G.C., Schultz L.R. Posttraumatic stress disorder and the incidence of nicotine, alcohol, and other drug disorders in persons who have experienced trauma. Archives of General Psychiatry 2003, 60:289-294.
30. Brewer D.D., Catalano R.F., Haggerty K., Gainey R.R., Fleming C.B. A meta-analysis of predictors of continued drug use during and after treatment for opiate addiction. Addiction 1998, 93:73-92.
31. Bruce K.R., Pihl R.O. Forget "drinking to forget": Enhanced consolidation of emotionally charged memory by alcohol. Experimental and Clinical Psychopharmacology 1997, 5:242-250.
32. Burke K.A., Franz T.M., Gugsa N., Schoenbaum G. Prior cocaine exposure disrupts extinction of fear conditioning. Learning & Memory 2006, 13:416-421.
33. Chandrasekar R. Alcohol and NMDA receptor: Current research and future direction. Frontiers in Molecular Neuroscience 2013, 6:14.
34. Chester J.A., Kirchhoff A.M., Barrenha G.D. Relation between corticosterone and fear-related behavior in mice selectively bred for high or low alcohol preference. Addiction Biology 2013.
35. Cleck J.N., Blendy J.A. Making a bad thing worse: Adverse effects of stress on drug addiction. J. Clin. Investig. 2008, 118:454-461.
36. Cottler L.B., Compton W.M., Mager D., Spitznagel E.L., Janca A. Posttraumatic stress disorder among substance users from the general population. The American Journal of Psychiatry 1992, 149:664-670.
37. Cunningham C.L. Flavor and location aversions produced by ethanol. Behavioral and Neural Biology 1979, 27:362-367.
38. Cunningham C.L., Clemans J.M., Fidler T.L. Injection timing determines whether intragastric ethanol produces conditioned place preference or aversion in mice. Pharmacology, Biochemistry and Behavior 2002, 72:659-668.
39. Danielson C.K., Amstadter A.B., Dangelmaier R.E., Resnick H.S., Saunders B.E., Kilpatrick D.G. Trauma-related risk factors for substance abuse among male versus female young adults. Addictive Behaviors 2009, 34:395-399.
40. Dansky B.S., Roitzsch J.C., Brady K.T., Saladin M.E. Posttraumatic stress disorder and substance abuse: Use of research in a clinical setting. Journal of Traumatic Stress 1997, 10:141-148.
41. Davis M. Neurobiology of fear responses: The role of the amygdala. The Journal of Neuropsychiatry and Clinical Neurosciences 1997, 9:382-402.
42. Davis J.A., Gould T.J. Beta2 subunit-containing nicotinic receptors mediate the enhancing effect of nicotine on trace cued fear conditioning in C57BL/6 mice. Psychopharmacology (Berl) 2007, 190:343-352.
43. Davis J.A., Gould T.J. Associative learning, the hippocampus, and nicotine addiction. Current Drug Abuse Reviews 2008, 1:9-19.
44. Davis J.A., Gould T.J. Hippocampal nAChRs mediate nicotine withdrawal-related learning deficits. European Neuropsychopharmacology: The Journal of the European College of Neuropsychopharmacology 2009, 19:551-561.
45. Davis J.A., James J.R., Siegel S.J., Gould T.J. Withdrawal from chronic nicotine administration impairs contextual fear conditioning in C57BL/6 mice. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience 2005, 25:8708-8713.
46. Davis J.A., Kenney J.W., Gould T.J. Hippocampal alpha4beta2 nicotinic acetylcholine receptor involvement in the enhancing effect of acute nicotine on contextual fear conditioning. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience 2007, 27:10870-10877.
47. Davis J.A., Porter J., Gould T.J. Nicotine enhances both foreground and background contextual fear conditioning. Neuroscience Letters 2006, 394:202-205.
48. de Kloet C.S., Vermetten E., Geuze E., Kavelaars A., Heijnen C.J., Westenberg H.G. Assessment of HPA-axis function in posttraumatic stress disorder: Pharmacological and non-pharmacological challenge tests, a review. Journal of Psychiatric Research 2006, 40:550-567.
49. De Soto C.B., O'Donnell W.E., Allred L.J., Lopes C.E. Symptomatology in alcoholics at various stages of abstinence. Alcoholism, Clinical and Experimental Research 1985, 9:505-512.
50. De Witte P., Pinto E., Ansseau M., Verbanck P. Alcohol and withdrawal: From animal research to clinical issues. Neuroscience and Biobehavioral Reviews 2003, 27:189-197.
51. Driessen M., Schulte S., Luedecke C., Schaefer I., Sutmann F., Ohlmeier M., et al. Trauma and PTSD in patients with alcohol, drug, or dual dependence: A multi-center study. Alcoholism, Clinical and Experimental Research 2008, 32:481-488.
52. Duka T., Gentry J., Malcolm R., Ripley T.L., Borlikova G., Stephens D.N., et al. Consequences of multiple withdrawals from alcohol. Alcoholism, Clinical and Experimental Research 2004, 28:233-246.
53. Duka T., Townshend J.M., Collier K., Stephens D.N. Impairment in cognitive functions after multiple detoxifications in alcoholic inpatients. Alcoholism, Clinical and Experimental Research 2003, 27:1563-1572.
54. Dutra L., Stathopoulou G., Basden S.L., Leyro T.M., Powers M.B., Otto M.W. A meta-analytic review of psychosocial interventions for substance use disorders. The American Journal of Psychiatry 2008, 165:179-187.
55. Elias G.A., Gulick D., Wilkinson D.S., Gould T.J. Nicotine and extinction of fear conditioning. Neuroscience 2010, 165:1063-1073.
56. Fein G. Lifetime and current mood and anxiety disorders in short-term and long-term abstinent alcoholics. Alcoholism, Clinical and Experimental Research 2013.
57. Fendt M., Fanselow M.S. The neuroanatomical and neurochemical basis of conditioned fear. Neuroscience and Biobehavioral Reviews 1999, 23:743-760.
58. Foa E.B., Zinbarg R., Rothbaum B.O. Uncontrollability and unpredictability in post-traumatic stress disorder: An animal model. Psychological Bulletin 1992, 112:218-238.
59. Fu S.S., McFall M., Saxon A.J., Beckham J.C., Carmody T.P., Baker D.G., et al. Post-traumatic stress disorder and smoking: A systematic review. Nicotine & Tobacco Research 2007, 9:1071-1084.
60. Gafford G.M., Guo J.D., Flandreau E.I., Hazra R., Rainnie D.G., Ressler K.J. Cell-type specific deletion of GABA(A)alpha1 in corticotropin-releasing factor-containing neurons enhances anxiety and disrupts fear extinction. Proceedings of the National academy of Sciences of the United States of America 2012, 109:16330-16335.
61. George D.T., Nutt D.J., Dwyer B.A., Linnoila M. Alcoholism and panic disorder: Is the comorbidity more than coincidence?. Acta Psychiatrica Scand. 1990, 81:97-107.
62. Givens B., McMahon K. Ethanol suppresses the induction of long-term potentiation in vivo. Brain Research 1995, 688:27-33.
63. Goosens K.A., Maren S. Long-term potentiation as a substrate for memory: Evidence from studies of amygdaloid plasticity and Pavlovian fear conditioning. Hippocampus 2002, 12:592-599.
64. Gordon M.K., Rosen J.B. Lasting effect of repeated cocaine administration on acoustic and fear-potentiated startle in rats. Psychopharmacology (Berl) 1999, 144:1-7.
65. Gould T.J. Ethanol disrupts fear conditioning in C57BL/6 mice. Journal of Psychopharmacology 2003, 17:77-81.
66. Gould T.J. Nicotine and hippocampus-dependent learning: Implications for addiction. Molecular Neurobiology 2006, 34:93-107.
67. Gould T.J., Feiro O., Moore D. Nicotine enhances trace cued fear conditioning but not delay cued fear conditioning in C57BL/6 mice. Behavioural Brain Research 2004, 155:167-173.
68. Gould T.J., Higgins J.S. Nicotine enhances contextual fear conditioning in C57BL/6J mice at 1 and 7 days post-training. Neurobiology of Learning and Memory 2003, 80:147-157.
69. Gould T.J., Portugal G.S., Andre J.M., Tadman M.P., Marks M.J., Kenney J.W., et al. The duration of nicotine withdrawal-associated deficits in contextual fear conditioning parallels changes in hippocampal high affinity nicotinic acetylcholine receptor upregulation. Neuropharmacology 2012, 62:2118-2125.
70. Greenberg J.B., Ameringer K.J., Trujillo M.A., Sun P., Sussman S., Brightman M., et al. Associations between posttraumatic stress disorder symptom clusters and cigarette smoking. Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors 2012, 26:89-98.
71. Gulick D., Gould T.J. Acute ethanol has biphasic effects on short- and long-term memory in both foreground and background contextual fear conditioning in C57BL/6 mice. Alcoholism, Clinical and Experimental Research 2007, 31:1528-1537.
72. Hall F.S., Sora I., Drgonova J., Li X.F., Goeb M., Uhl G.R. Molecular mechanisms underlying the rewarding effects of cocaine. Annals of the New York Academy of Sciences 2004, 1025:47-56.
73. Hapke U., Schumann A., Rumpf H.J., John U., Konerding U., Meyer C. Association of smoking and nicotine dependence with trauma and posttraumatic stress disorder in a general population sample. The Journal of Nervous and Mental Disease 2005, 193:843-846.
74. Hariri A.R., Bookheimer S.Y., Mazziotta J.C. Modulating emotional responses: Effects of a neocortical network on the limbic system. NeuroReport 2000, 11:43-48.
75. Hewitt G.P., Holder M., Laird J. Retrograde enhancement of human kinesthetic memory by alcohol: Consolidation or protection against interference?. Neurobiology of Learning and Memory 1996, 65:269-277.
76. Holmes A., Fitzgerald P.J., MacPherson K.P., DeBrouse L., Colacicco G., Flynn S.M., et al. Chronic alcohol remodels prefrontal neurons and disrupts NMDAR-mediated fear extinction encoding. Nature Neuroscience 2012, 15:1359-1361.
77. Hunt P.S., Levillain M.E., Spector B.M., Kostelnik L.A. Post-training ethanol disrupts trace conditioned fear in rats: Effects of timing of ethanol, dose and trace interval duration. Neurobiology of Learning and Memory 2009, 91:73-80.
78. Hyman S.E., Malenka R.C., Nestler E.J. Neural mechanisms of addiction: The role of reward-related learning and memory. Annual Review of Neuroscience 2006, 29:565-598.
79. Jacobsen L.K., Southwick S.M., Kosten T.R. Substance use disorders in patients with posttraumatic stress disorder: A review of the literature. The American Journal of Psychiatry 2001, 158:1184-1190.
80. Jorenby D.E., Hays J.T., Rigotti N.A., Azoulay S., Watsky E.J., Williams K.E., et al. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: A randomized controlled trial. JAMA, the Journal of the American Medical Association 2006, 296:56-63.
81. Joseph S., Yule W., Williams R., Hodgkinson P. Increased substance use in survivors of the Herald of Free Enterprise disaster. The British Journal of Medical Psychology 1993, 66(Pt 2):185-191.
82. Karl A., Schaefer M., Malta L.S., Dorfel D., Rohleder N., Werner A. A meta-analysis of structural brain abnormalities in PTSD. Neuroscience and Biobehavioral Reviews 2006, 30:1004-1031.
83. Kenney J.W., Florian C., Portugal G.S., Abel T., Gould T.J. Involvement of hippocampal jun-N terminal kinase pathway in the enhancement of learning and memory by nicotine. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 2010, 35:483-492.
84. Kenney J.W., Gould T.J. Modulation of hippocampus-dependent learning and synaptic plasticity by nicotine. Molecular Neurobiology 2008, 38:101-121.
85. Kenney J.W., Poole R.L., Adoff M.D., Logue S.F., Gould T.J. Learning and nicotine interact to increase CREB phosphorylation at the jnk1 promoter in the hippocampus. PLoS ONE 2012, 7:e39939.
86. Kenney J.W., Wilkinson D.S., Gould T.J. The enhancement of contextual fear conditioning by ABT-418. Behavioural Pharmacology 2010, 21:246-249.
87. Kessler R.C., Sonnega A., Bromet E., Hughes M., Nelson C.B. Posttraumatic stress disorder in the National Comorbidity Survey. Archives of General Psychiatry 1995, 52:1048-1060.
88. Khoury L., Tang Y.L., Bradley B., Cubells J.F., Ressler K.J. Substance use, childhood traumatic experience, and Posttraumatic Stress Disorder in an urban civilian population. Depression and Anxiety 2010, 27:1077-1086.
89. Kim J.J., Jung M.W. Neural circuits and mechanisms involved in Pavlovian fear conditioning: A critical review. Neuroscience and Biobehavioral Reviews 2006, 30:188-202.
90. Kitaichi K., Minami Y., Amano M., Yamada K., Hasegawa T., Nabeshima T. The attenuation of suppression of motility by triazolam in the conditioned fear stress task is exacerbated by ethanol in mice. Life Sciences 1995, 57:743-753.
91. Kokka N., Sapp D.W., Taylor A.M., Olsen R.W. The kindling model of alcohol dependence: Similar persistent reduction in seizure threshold to pentylenetetrazol in animals receiving chronic ethanol or chronic pentylenetetrazol. Alcoholism, Clinical and Experimental Research 1993, 17:525-531.
92. Kolassa I.T., Kolassa S., Ertl V., Papassotiropoulos A., De Quervain D.J. The risk of posttraumatic stress disorder after trauma depends on traumatic load and the catechol-o-methyltransferase Val(158)Met polymorphism. Biological Psychiatry 2010, 67:304-308.
93. Koob G.F., Le Moal M. Review. Neurobiological mechanisms for opponent motivational processes in addiction. Philosophical Transactions of the Royal Society of London. Series B, Biological sciences 2008, 363:3113-3123.
94. Koob G.F., Volkow N.D. Neurocircuitry of addiction. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 2010, 35:217-238.
95. Kushner M.G., Abrams K., Thuras P., Hanson K.L., Brekke M., Sletten S. Follow-up study of anxiety disorder and alcohol dependence in comorbid alcoholism treatment patients. Alcoholism, Clinical and Experimental Research 2005, 29:1432-1443.
96. Kuzmin A., Liljequist S., Meis J., Chefer V., Shippenberg T., Bakalkin G. Repeated moderate-dose ethanol bouts impair cognitive function in Wistar rats. Addiction Biology 2012, 17:132-140.
97. Lack A.K., Diaz M.R., Chappell A., DuBois D.W., McCool B.A. Chronic ethanol and withdrawal differentially modulate pre- and postsynaptic function at glutamatergic synapses in rat basolateral amygdala. Journal of Neurophysiology 2007, 98:3185-3196.
98. Lasser K., Boyd J.W., Woolhandler S., Himmelstein D.U., McCormick D., Bor D.H. Smoking and mental illness: A population-based prevalence study. JAMA, the Journal of the American Medical Association 2000, 284:2606-2610.
99. Lattal K.M. Effects of ethanol on encoding, consolidation, and expression of extinction following contextual fear conditioning. Behavioral Neuroscience 2007, 121:1280-1292.
100. Lattal K.M., Lattal K.A. Facets of Pavlovian and operant extinction. Behavioral Processes 2012, 90:1-8.
101. Le Foll B., Goldberg S.R. Nicotine induces conditioned place preferences over a large range of doses in rats. Psychopharmacology (Berl) 2005, 178:481-492.
102. LeDoux J. Emotional networks and motor control: A fearful view. Progress in Brain Research 1996, 107:437-446.
103. Lerman C. Helping smokers quit through pharmacogenetics. LDI Issue Brief 2006, 11:1-4.
104. Little H.J., Stephens D.N., Ripley T.L., Borlikova G., Duka T., Schubert M., et al. Alcohol withdrawal and conditioning. Alcoholism, Clinical and Experimental Research 2005, 29:453-464.
105. Littleton J., Little H. Current concepts of ethanol dependence. Addiction 1994, 89:1397-1412.
106. Liu X., Weiss F. Additive effect of stress and drug cues on reinstatement of ethanol seeking: Exacerbation by history of dependence and role of concurrent activation of corticotropin-releasing factor and opioid mechanisms. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 2002, 22:7856-7861.
107. Livingstone P.D., Wonnacott S. Nicotinic acetylcholine receptors and the ascending dopamine pathways. Biochemical Pharmacology 2009, 78:744-755.
108. Logrip M.L., Zorrilla E.P., Koob G.F. Stress modulation of drug self-administration: Implications for addiction comorbidity with post-traumatic stress disorder. Neuropharmacology 2012, 62:552-564.
109. Loughead J., Ray R., Wileyto E.P., Ruparel K., Sanborn P., Siegel S., et al. Effects of the alpha4beta2 partial agonist varenicline on brain activity and working memory in abstinent smokers. Biological Psychiatry 2010, 67:715-721.
110. Lovinger D.M., White G., Weight F.F. Ethanol inhibits NMDA-activated ion current in hippocampal neurons. Science 1989, 243:1721-1724.
111. Lundqvist T. Cognitive consequences of cannabis use: Comparison with abuse of stimulants and heroin with regard to attention, memory and executive functions. Pharmacology, Biochemistry and Behavior 2005, 81:319-330.
112. Maier S.F. Exposure to the stressor environment prevents the temporal dissipation of behavioral depression/learned helplessness. Biological Psychiatry 2001, 49:763-773.
113. Malin D.H., Goyarzu P. Rodent models of nicotine withdrawal syndrome. Handbook of Experimental Pharmacology 2009, 401-434.
114. Mann K., Gunther A., Stetter F., Ackermann K. Rapid recovery from cognitive deficits in abstinent alcoholics: A controlled test-retest study. Alcohol and Alcoholism 1999, 34:567-574.
115. Maroun M., Ioannides P.J., Bergman K.L., Kavushansky A., Holmes A., Wellman C.L. Fear extinction deficits following acute stress associate with increased spine density and dendritic retraction in basolateral amygdala neurons. The European Journal of Neuroscience 2013, 4:2611-2620.
116. McCool B.A., Christian D.T., Diaz M.R., Lack A.K. Glutamate plasticity in the drunken amygdala: The making of an anxious synapse. International Review of Neurobiology 2010, 91:205-233.
117. McEchron M.D., Bouwmeester H., Tseng W., Weiss C., Disterhoft J.F. Hippocampectomy disrupts auditory trace fear conditioning and contextual fear conditioning in the rat. Hippocampus 1998, 8:638-646.
118. McFall M.E., Mackay P.W., Donovan D.M. Combat-related posttraumatic stress disorder and severity of substance abuse in Vietnam veterans. Journal of Studies on Alcohol 1992, 53:357-363.
119. Melia K.R., Ryabinin A.E., Corodimas K.P., Wilson M.C., Ledoux J.E. Hippocampal-dependent learning and experience-dependent activation of the hippocampus are preferentially disrupted by ethanol. Neuroscience 1996, 74:313-322.
120. Mihic S.J., Ye Q., Wick M.J., Koltchine V.V., Krasowski M.D., Finn S.E., et al. Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature 1997, 389:385-389.
121. Milad M.R., Quirk G.J. Neurons in medial prefrontal cortex signal memory for fear extinction. Nature 2002, 420:70-74.
122. Mills K.L., Teesson M., Ross J., Peters L. Trauma, PTSD, and substance use disorders: Findings from the Australian National Survey of Mental Health and Well-Being. The American Journal of Psychiatry 2006, 163:652-658.
123. Morey R.A., Gold A.L., LaBar K.S., Beall S.K., Brown V.M., Haswell C.C., et al. Amygdala volume changes in posttraumatic stress disorder in a large case-controlled veterans group. Archives of General Psychiatry 2012, 69:1169-1178.
124. Morrisett R.A., Swartzwelder H.S. Attenuation of hippocampal long-term potentiation by ethanol: A patch-clamp analysis of glutamatergic and GABAergic mechanisms. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience 1993, 13:2264-2272.
125. Muller T., Albrecht D., Gebhardt C. Both NR2A and NR2B subunits of the NMDA receptor are critical for long-term potentiation and long-term depression in the lateral amygdala of horizontal slices of adult mice. Learning & Memory 2009, 16:395-405.
126. Murphy C.A., Heidbreder C., Feldon J. Acute withdrawal from repeated cocaine treatment enhances latent inhibition of a conditioned fear response. Behavioural Pharmacology 2001, 12:13-23.
127. Neuner F., Schauer M., Karunakara U., Klaschik C., Robert C., Elbert T. Psychological trauma and evidence for enhanced vulnerability for posttraumatic stress disorder through previous trauma among West Nile refugees. BMC Psychiatry 2004, 4:34.
128. O'Brien C.P., Childress A.R., Ehrman R., Robbins S.J. Conditioning factors in drug abuse: Can they explain compulsion?. Journal of Psychopharmacology 1998, 12:15-22.
129. O'Daly O.G., Trick L., Scaife J., Marshall J., Ball D., Phillips M.L., et al. Withdrawal-associated increases and decreases in functional neural connectivity associated with altered emotional regulation in alcoholism. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 2012, 37:2267-2276.
130. Overstreet D.H., Knapp D.J., Breese G.R. Accentuated decrease in social interaction in rats subjected to repeated ethanol withdrawals. Alcoholism, Clinical and Experimental Research 2002, 26:1259-1268.
131. Parsons R.G., Ressler K.J. Implications of memory modulation for post-traumatic stress and fear disorders. Nature Neuroscience 2013, 16:146-153.
132. Patterson F., Jepson C., Loughead J., Perkins K., Strasser A.A., Siegel S., et al. Working memory deficits predict short-term smoking resumption following brief abstinence. Drug and Alcohol Dependence 2010, 106:61-64.
133. Patterson F., Jepson C., Strasser A.A., Loughead J., Perkins K.A., Gur R.C., et al. Varenicline improves mood and cognition during smoking abstinence. Biological Psychiatry 2009, 65:144-149.
134. Penberthy J.K., Ait-Daoud N., Vaughan M., Fanning T. Review of treatment for cocaine dependence. Current Drug Abuse Reviews 2010, 3:49-62.
135. Pezze M.A., Feldon J. Mesolimbic dopaminergic pathways in fear conditioning. Progress in Neurobiology 2004, 74:301-320.
136. Phillips R.G., LeDoux J.E. Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behavioral Neuroscience 1992, 106:274-285.
137. Piazza P.V., Deminiere J.M., le Moal M., Simon H. Stress- and pharmacologically-induced behavioral sensitization increases vulnerability to acquisition of amphetamine self-administration. Brain Research 1990, 514:22-26.
138. Pietrzak R.H., Goldstein R.B., Southwick S.M., Grant B.F. Prevalence and Axis I comorbidity of full and partial posttraumatic stress disorder in the United States: Results from Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions. Journal of Anxiety Disorders 2011, 25:456-465.
139. Pinel J.P. Alcohol withdrawal seizures: Implications of kindling. Pharmacology, Biochemistry and Behavior 1980, 13(Suppl 1):225-231.
140. Rasmussen D.D., Boldt B.M., Bryant C.A., Mitton D.R., Larsen S.A., Wilkinson C.W. Chronic daily ethanol and withdrawal: 1. Long-term changes in the hypothalamo-pituitary-adrenal axis. Alcoholism, Clinical and Experimental Research 2000, 24:1836-1849.
141. Rau V., DeCola J.P., Fanselow M.S. Stress-induced enhancement of fear learning: An animal model of posttraumatic stress disorder. Neuroscience and Biobehavioral Reviews 2005, 29:1207-1223.
142. Rauch S.L., Whalen P.J., Shin L.M., McInerney S.C., Macklin M.L., Lasko N.B., et al. Exaggerated amygdala response to masked facial stimuli in posttraumatic stress disorder: A functional MRI study. Biological Psychiatry 2000, 47:769-776.
143. Raybuck J.D., Gould T.J. Extracellular signal-regulated kinase 1/2 involvement in the enhancement of contextual fear conditioning by nicotine. Behavioral Neuroscience 2007, 121:1119-1124.
144. Raybuck J.D., Gould T.J. Nicotine withdrawal-induced deficits in trace fear conditioning in C57BL/6 mice - A role for high-affinity beta2 subunit-containing nicotinic acetylcholine receptors. The European Journal of Neuroscience 2009, 29:377-387.
145. Raybuck J.D., Gould T.J. The role of nicotinic acetylcholine receptors in the medial prefrontal cortex and hippocampus in trace fear conditioning. Neurobiology of Learning and Memory 2010, 94:353-363.
146. Raybuck J.D., Lattal K.M. Double dissociation of amygdala and hippocampal contributions to trace and delay fear conditioning. PLoS ONE 2011, 6:e15982.
147. Raybuck J.D., Portugal G.S., Lerman C., Gould T.J. Varenicline ameliorates nicotine withdrawal-induced learning deficits in C57BL/6 mice. Behavioral Neuroscience 2008, 122:1166-1171.
148. Ripley T.L., O'Shea M., Stephens D.N. Repeated withdrawal from ethanol impairs acquisition but not expression of conditioned fear. The European Journal of Neuroscience 2003, 18:441-448.
149. Roberto M., Gilpin N.W., Siggins G.R. The central amygdala and alcohol: Role of gamma-aminobutyric acid, glutamate, and neuropeptides. Cold Spring Harbor Perspectives in Medicine 2012, 2:a012195.
150. Roberto M., Madamba S.G., Stouffer D.G., Parsons L.H., Siggins G.R. Increased GABA release in the central amygdala of ethanol-dependent rats. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience 2004, 24:10159-10166.
151. Rodriguez W.A., Phillips M.Y., Rodriguez S.B., Martinez J.L. Cocaine administration prior to reactivation facilitates later acquisition of an avoidance response in rats. Psychopharmacology (Berl) 1993, 112:366-370.
152. Rogan M.T., Staubli U.V., LeDoux J.E. Fear conditioning induces associative long-term potentiation in the amygdala. Nature 1997, 390:604-607.
153. Rollema H., Chambers L.K., Coe J.W., Glowa J., Hurst R.S., Lebel L.A., et al. Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid. Neuropharmacology 2007, 52:985-994.
154. Rossetti Z.L., Carboni S., Fadda F. Glutamate-induced increase of extracellular glutamate through N-methyl-D-aspartate receptors in ethanol withdrawal. Neuroscience 1999, 93:1135-1140.
155. Runyan J.D., Dash P.K. Intra-medial prefrontal administration of SCH-23390 attenuates ERK phosphorylation and long-term memory for trace fear conditioning in rats. Neurobiology of Learning and Memory 2004, 82:65-70.
156. Saladin M.E., Brady K.T., Dansky B.S., Kilpatrick D.G. Understanding comorbidity between PTSD and substance use disorders: Two preliminary investigations. Addictive Behaviors 1995, 20:643-655.
157. Samson H.H., Harris R.A. Neurobiology of alcohol abuse. Trends in Pharmacological Sciences 1992, 13:206-211.
158. Sartor C.E., McCutcheon V.V., Pommer N.E., Nelson E.C., Grant J.D., Duncan A.E., et al. Common genetic and environmental contributions to post-traumatic stress disorder and alcohol dependence in young women. Psychological Medicine 2011, 41:1497-1505.
159. Schulkin J., Gold P.W., McEwen B.S. Induction of corticotropin-releasing hormone gene expression by glucocorticoids: Implication for understanding the states of fear and anxiety and allostatic load. Psychoneuroendocrinology 1998, 23:219-243.
160. Shin L.M., Orr S.P., Carson M.A., Rauch S.L., Macklin M.L., Lasko N.B., et al. Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSD. Archives of General Psychiatry 2004, 61:168-176.
161. Siegmund A., Wotjak C.T. A mouse model of posttraumatic stress disorder that distinguishes between conditioned and sensitised fear. Journal of Psychiatric Research 2007, 41:848-860.
162. Sierra-Mercado D., Padilla-Coreano N., Quirk G.J. Dissociable roles of prelimbic and infralimbic cortices, ventral hippocampus, and basolateral amygdala in the expression and extinction of conditioned fear. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 2011, 36:529-538.
163. Smith M.A., Davidson J., Ritchie J.C., Kudler H., Lipper S., Chappell P., et al. The corticotropin-releasing hormone test in patients with posttraumatic stress disorder. Biological Psychiatry 1989, 26:349-355.
164. Sofuoglu M., DeVito E.E., Waters A.J., Carroll K.M. Cognitive enhancement as a treatment for drug addictions. Neuropharmacology 2013, 64:452-463.
165. Solomon R.L., Corbit J.D. An opponent-process theory of motivation. I. Temporal dynamics of affect. Psychological Review 1974, 81:119-145.
166. Sorocco K.H., Lovallo W.R., Vincent A.S., Collins F.L. Blunted hypothalamic-pituitary-adrenocortical axis responsivity to stress in persons with a family history of alcoholism. International Journal of Psychophysiology: Official Journal of the International Organization of Psychophysiology 2006, 59:210-217.
167. Sotres-Bayon F., Quirk G.J. Prefrontal control of fear: More than just extinction. Current Opinion in Neurobiology 2010, 20:231-235.
168. Stafford J.M., Raybuck J.D., Ryabinin A.E., Lattal K.M. Increasing histone acetylation in the hippocampus-infralimbic network enhances fear extinction. Biological Psychiatry 2012, 72:25-33.
169. Stephens D.N., Brown G., Duka T., Ripley T.L. Impaired fear conditioning but enhanced seizure sensitivity in rats given repeated experience of withdrawal from alcohol. The European Journal of Neuroscience 2001, 14:2023-2031.
170. Stephens D.N., Duka T. Review. Cognitive and emotional consequences of binge drinking: Role of amygdala and prefrontal cortex. Philosophical Transactions of the Royal Society of London. Series B, Biological sciences 2008, 363:3169-3179.
171. Stephens D.N., Ripley T.L., Borlikova G., Schubert M., Albrecht D., Hogarth L., et al. Repeated ethanol exposure and withdrawal impairs human fear conditioning and depresses long-term potentiation in rat amygdala and hippocampus. Biological Psychiatry 2005, 58:392-400.
172. Stromberg M.F., Hammond L.J. The effects of ethanol on a measure of conditioned fear in mice. Alcohol 1997, 14:403-407.
173. Talani G., Biggio G., Sanna E. Enhanced sensitivity to ethanol-induced inhibition of LTP in CA1 pyramidal neurons of socially isolated C57BL/6J mice: Role of neurosteroids. Frontiers in Endocrinology 2011, 2:56.
174. Torregrossa M.M., Corlett P.R., Taylor J.R. Aberrant learning and memory in addiction. Neurobiology of Learning and Memory 2011, 96:609-623.
175. Townshend J.M., Duka T. Mixed emotions: Alcoholics' impairments in the recognition of specific emotional facial expressions. Neuropsychologia 2003, 41:773-782.
176. Trevisan L., Fitzgerald L.W., Brose N., Gasic G.P., Heinemann S.F., Duman R.S., et al. Chronic ingestion of ethanol up-regulates NMDAR1 receptor subunit immunoreactivity in rat hippocampus. Journal of Neurochemistry 1994, 62:1635-1638.
177. Tull M.T., McDermott M.J., Gratz K.L., Coffey S.F., Lejuez C.W. Cocaine-related attentional bias following trauma cue exposure among cocaine dependent in-patients with and without post-traumatic stress disorder. Addiction 2011, 106:1810-1818.
178. Ullman S.E., Filipas H.H., Townsend S.M., Starzynski L.L. Trauma exposure, posttraumatic stress disorder and problem drinking in sexual assault survivors. Journal of Studies on Alcohol 2005, 66:610-619.
179. Valdez G.R., Zorrilla E.P., Roberts A.J., Koob G.F. Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence. Alcohol 2003, 29:55-60.
180. Veatch L.M., Gonzalez L.P. Repeated ethanol withdrawal delays development of focal seizures in hippocampal kindling. Alcoholism, Clinical and Experimental Research 1999, 23:1145-1150.
181. Vernino S., Amador M., Luetje C.W., Patrick J., Dani J.A. Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors. Neuron 1992, 8:127-134.
182. Volkow N.D., Wang G.J., Telang F., Fowler J.S., Logan J., Childress A.R., et al. Dopamine increases in striatum do not elicit craving in cocaine abusers unless they are coupled with cocaine cues. NeuroImage 2008, 39:1266-1273.
183. Volpicelli J., Balaraman G., Hahn J., Wallace H., Bux D. The role of uncontrollable trauma in the development of PTSD and alcohol addiction. Alcohol Research & Health: The Journal of The National Institute on Alcohol Abuse and Alcoholism 1999, 23:256-262.
184. Volpicelli J.R., Ulm R.R., Hopson N. The bidirectional effects of shock on alcohol preference in rats. Alcoholism, Clinical and Experimental Research 1990, 14:913-916.
185. Vrana S.R., Calhoun P.S., McClernon F.J., Dennis M.F., Lee S.T., Beckham J.C. Effects of smoking on the acoustic startle response and prepulse inhibition in smokers with and without posttraumatic stress disorder. Psychopharmacology (Berl) 2013.
186. Vyas A., Mitra R., Shankaranarayana Rao B.S., Chattarji S. Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons. Journal of Neuroscience 2002, 22:6810-6818.
187. Waldrop A.E., Back S.E., Verduin M.L., Brady K.T. Triggers for cocaine and alcohol use in the presence and absence of posttraumatic stress disorder. Addictive Behaviors 2007, 32:634-639.
188. Walker D.L., Davis M. Amygdala infusions of an NR2B-selective or an NR2A-preferring NMDA receptor antagonist differentially influence fear conditioning and expression in the fear-potentiated startle test. Learning & Memory 2008, 15:67-74.
189. Walker D.L., Paschall G.Y., Davis M. Glutamate receptor antagonist infusions into the basolateral and medial amygdala reveal differential contributions to olfactory vs. context fear conditioning and expression. Learning & Memory 2005, 12:120-129.
190. Weissenborn R., Duka T. Acute alcohol effects on cognitive function in social drinkers: Their relationship to drinking habits. Psychopharmacology (Berl) 2003, 165:306-312.
191. Weitemier A.Z., Ryabinin A.E. Alcohol-induced memory impairment in trace fear conditioning: A hippocampus-specific effect. Hippocampus 2003, 13:305-315.
192. White A.M., Best P.J. Effects of ethanol on hippocampal place-cell and interneuron activity. Brain Research 2000, 876:154-165.
193. Willick M.L., Kokkinidis L. Cocaine enhances the expression of fear-potentiated startle: Evaluation of state-dependent extinction and the shock-sensitization of acoustic startle. Behavioral Neuroscience 1995, 109:929-938.
194. Woicik P.A., Moeller S.J., Alia-Klein N., Maloney T., Lukasik T.M., Yeliosof O., et al. The neuropsychology of cocaine addiction: Recent cocaine use masks impairment. Neuropsychopharmacology: Official Publication of The American College of Neuropsychopharmacology 2009, 34:1112-1122.
195. Wood S.C., Fay J., Sage J.R., Anagnostaras S.G. Cocaine and Pavlovian fear conditioning: Dose-effect analysis. Behavioural Brain Research 2007, 176:244-250.
196. Wrase J., Makris N., Braus D.F., Mann K., Smolka M.N., Kennedy D.N., et al. Amygdala volume associated with alcohol abuse relapse and craving. The American Journal of Psychiatry 2008, 165:1179-1184.
197. Xian H., Chantarujikapong S.I., Scherrer J.F., Eisen S.A., Lyons M.J., Goldberg J., et al. Genetic and environmental influences on posttraumatic stress disorder, alcohol and drug dependence in twin pairs. Drug and Alcohol Dependence 2000, 61:95-102.
198. Yehuda R. Biology of posttraumatic stress disorder. The Journal of Clinical Psychiatry 2001, 62(Suppl 17):41-46.
199. Yehuda R., Keefe R.S., Harvey P.D., Levengood R.A., Gerber D.K., Geni J., et al. Learning and memory in combat veterans with posttraumatic stress disorder. The American Journal of Psychiatry 1995, 152:137-139.
200. Yttri E.A., Burk J.A., Hunt P.S. Intermittent ethanol exposure in adolescent rats: Dose-dependent impairments in trace conditioning. Alcoholism, Clinical and Experimental Research 2004, 28:1433-1436.
201. Yu G., Chen H., Wu X., Matta S.G., Sharp B.M. Nicotine self-administration differentially modulates glutamate and GABA transmission in hypothalamic paraventricular nucleus to enhance the hypothalamic-pituitary-adrenal response to stress. Journal of Neurochemistry 2010, 113:919-929.
202. Yu G., Sharp B.M. Nicotine self-administration diminishes stress-induced norepinephrine secretion but augments adrenergic-responsiveness in the hypothalamic paraventricular nucleus and enhances adrenocorticotropic hormone and corticosterone release. Journal of Neurochemistry 2010, 112:1327-1337.