The enhancement of contextual fear conditioning by ABT-418

Behavioural Pharmacology

Volumn 21, Issue 3, 2010, Pages 246-249

  Kenney, Justin W ^a   Wilkinson, Derek S ^a   Gould, Thomas J ^a  

^a TEMPLE UNIVERSITY   (United States)

Author keywords

ABT 418; Acetylcholine; Learning; Memory; Mouse; Nicotine; Nicotinic acetylcholine receptors

Indexed keywords

3 METHYL 5 (1 METHYL 2 PYRROLIDINYL)ISOXAZOLE; NICOTINIC RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CONDITIONING; CONTEXTUAL FEAR CONDITIONING; CONTROLLED STUDY; DOSE RESPONSE; MALE; MEMORY; MOUSE; NONHUMAN;

ACOUSTIC STIMULATION; ANIMALS; ANTI-ANXIETY AGENTS; BIOPHYSICS; CONDITIONING, CLASSICAL; ELECTROSHOCK; FEAR; ISOXAZOLES; MALE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; PYRROLIDINES; STATISTICS, NONPARAMETRIC; VOCALIZATION, ANIMAL;

EID: 77952426072     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/FBP.0b013e32833a5b9d     Document Type: Article

References (27)

1. Albuquerque EX, Alkondon M, Pereira EF, Castro NG, Schrattenholz A, Barbosa CT, et al. (1997). Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function. J Pharmacol Exp Ther 280:1117-1136.
2. Arneric SP, Sullivan JP, Briggs CA, Donnelly-Roberts D, Anderson DJ, Raszkiewicz JL, et al. (1994). (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: I. In vitro characterization. J Pharmacol Exp Ther 270:310-318.
3. Covernton PJ, Kojima H, Sivilotti LG, Gibb AJ, Colquhoun D (1994). Comparison of neuronal nicotinic receptors in rat sympathetic neurones with subunit pairs expressed in Xenopus oocytes. J Physiol 481 (Pt 1):27-34.
4. Davis JA, Gould TJ (2007). Beta2 subunit-containing nicotinic receptors mediate the enhancing effect of nicotine on trace cued fear conditioning in C57BL/6 mice. Psychopharmacology (Berl) 190:343-352.
5. Decker MW, Brioni JD, Sullivan JP, Buckley MJ, Radek RJ, Raszkiewicz JL, et al. (1994). (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT-418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: II. In vivo characterization. J Pharmacol Exp Ther 270:319-328.
6. Dineley-Miller K, Patrick J (1992). Gene transcripts for the nicotinic acetylcholine receptor subunit, beta4, are distributed in multiple areas of the rat central nervous system. Brain Res Mol Brain Res 16:339-344.
7. Gould TJ, Feiro O, Moore D (2004). Nicotine enhances trace cued fear conditioning but not delay cued fear conditioning in C57BL/6 mice. Behav Brain Res 155:167-173.
8. Gulick D, Gould TJ (2009). The hippocampus and cingulate cortex differentially mediate the effects of nicotine on learning versus on ethanol-induced learning deficits through different effects at nicotinic receptors. Neuropsychopharma-cology 34:2167-2179.
9. Hahn B, Sharples CG, Wonnacott S, Shoaib M, Stolerman IP (2003). Attentional effects of nicotinic agonists in rats. Neuropharmacology 44:1054-1067.
10. Hogg RC, Raggenbass M, Bertrand D (2003). Nicotinic acetylcholine receptors: from structure to brain function. Rev Physiol Biochem Pharmacol 147:1-46.
11. Holladay MW, Dart MJ, Lynch JK (1997). Neuronal nicotinic acetylcholine receptors as targets for drug discovery. J Med Chem 40:4169-4194.
12. Kenney JW, Gould TJ (2008a). Modulation of hippocampus-dependent learning and synaptic plasticity by nicotine. Mol Neurobiol 38:101-121.
13. Kenney JW, Gould TJ (2008b). Nicotine enhances context learning but not context-shock associative learning. Behav Neurosci 122:1158-1165.
14. Kim JJ, Fanselow MS (1992). Modality-specific retrograde amnesia of fear. Science 256:675-677.
15. Luetje CW, Patrick J (1991). Both alpha-and beta-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors. J Neurosci 11:837-845.
16. McGaughy J, Decker MW, Sarter M (1999). Enhancement of sustained attention performance by the nicotinic acetylcholine receptor agonist ABT-418 in intact but not basal forebrain-lesioned rats. Psychopharmacology (Berl) 144:175-182.
17. McGehee DS, Role LW (1995). Physiological diversity of nicotinic acetyl-choline receptors expressed by vertebrate neurons. Annu Rev Physiol 57:521-546.
18. Millar NS, Gotti C (2009). Diversity of vertebrate nicotinic acetylcholine receptors. Neuropharmacology 56:237-246.
19. Papke RL, Thinschmidt JS, Moulton BA, Meyer EM, Poirier A (1997). Activation and inhibition of rat neuronal nicotinic receptors by ABT-418. Br J Pharmacol 120:429-438.
20. Placzek AN, Zhang TA, Dani JA (2009). Nicotinic mechanisms influencing synaptic plasticity in the hippocampus. Acta Pharmacol Sin 30:752-760.
21. Potter A, Corwin J, Lang J, Piasecki M, Lenox R, Newhouse PA (1999). Acute effects of the selective cholinergic channel activator (nicotinic agonist) ABT-418 in Alzheimer's disease. Psychopharmacology (Berl) 142:334-342.
22. Prendergast MA, Terry AV Jr, Jackson WJ, Marsh KC, Decker MW, Arneric SP, Buccafusco JJ (1997). Improvement in accuracy of delayed recall in aged and non-aged, mature monkeys after intramuscular or transdermal administration of the CNS nicotinic receptor agonist ABT-418. Psychopharmacology (Berl) 130:276-284.
23. Prendergast MA, Jackson WJ, Terry AV Jr, Decker MW, Arneric SP, Buccafusco JJ (1998). Central nicotinic receptor agonists ABT-418, ABT-089, and (-) nicotine reduce distractibility in adult monkeys. Psychopharmacology (Berl) 136:50-58.
24. Rudy JW, Huff NC, Matus-Amat P (2004). Understanding contextual fear conditioning: insights from a two-process model. Neurosci Biobehav Rev 28:675-685.
25. Wada E, Wada K, Boulter J, Deneris E, Heinemann S, Patrick J, Swanson LW (1989). Distribution of alpha 2, alpha 3, alpha 4, and beta 2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the rat. J Comp Neurol 284:314-335.
26. Wehner JM, Keller JJ, Keller AB, Picciotto MR, Paylor R, Booker TK, et al. (2004). Role of neuronal nicotinic receptors in the effects of nicotine and ethanol on contextual fear conditioning. Neuroscience 129:11-24.
27. Wilens TE, Biederman J, Spencer TJ, Bostic J, Prince J, Monuteaux MC, et al. (1999). A pilot controlled clinical trial of ABT-418, a cholinergic agonist, in the treatment of adults with attention deficit hyperactivity disorder. Am J Psychiatry 156:1931-1937.