Effects of alcohol on the acquisition and expression of fear-potentiated startle in mouse lines selectively bred for high and low alcohol preference

Psychopharmacology

Volumn 218, Issue 1, 2011, Pages 191-201

  Barrenha, Gustavo D ^a   Coon, Laran E ^a   Chester, Julia A ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Alcohol; Anxiety; Behavior; Fear; Genetics; Startle; Stress

Indexed keywords

ALCOHOL; DIAZEPAM;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANXIETY; ARTICLE; CHEMOSENSITIVITY; CONTROLLED STUDY; DRINKING BEHAVIOR; DRUG PREFERENCE; EXPERIMENTAL STUDY; FEAR; FEAR POTENTIATED STARTLE; FEMALE; GENETIC ASSOCIATION; GENETIC TRAIT; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; REINFORCEMENT; SENSITIVITY ANALYSIS; STRAIN DIFFERENCE; TRANQUILIZING ACTIVITY;

ALCOHOL-RELATED DISORDERS; ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; DIAZEPAM; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; FEAR; FEMALE; MALE; MICE; STARTLE REACTION;

EID: 82955235550     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-011-2285-5     Document Type: Article

References (84)

1. Abrams K, KushnerM,Medina KL, Voight A (2001) The pharmacologic and expectancy effects of alcohol on social anxiety in individuals with social phobia. Drug Alcohol Depend 64:219-231 (Pubitemid 32816965)
2. Barrenha GD, Chester JA (2007) Genetic correlation between innate alcohol preference and fear-potentiated startle in selected mouse lines. Alcohol Clin Exp Res 31:1081-1088 (Pubitemid 46934380)
3. Blanchard RJ, Magee L, Veniegas R, Blanchard DC (1993) Alcohol and anxiety: Ethopharmacological approaches. Prog Neuropsychopharmacol Biol Psychiatry 17:171-182 (Pubitemid 23024084)
4. Boehm SL, Reed CL, McKinnon CS, Phillips TJ (2002) Shared genes influence sensitivity to the effects of ethanol on locomotor and anxiety-like behaviors, and the stress axis. Psychopharmacology (Berl) 161:54-63 (Pubitemid 34437969)
5. Bowen RC, Cipywnyk D, D'Arcy C, Keegan D (1984) Alcoholism, anxiety disorders, and agoraphobia. Alcohol Clin Exp Res 8:48-50 (Pubitemid 14156023)
6. Brady KT, Killeen TK, Brewerton T, Lucerini S (2000) Comorbidity of psychiatric disorders and posttraumatic stress disorder. J Clin Psychiatry 61(Suppl 7):22-32 (Pubitemid 30233561)
7. Brown PJ, Sout RL, Gannon-Rowley J (1998) Substance use disorder-PTSD comorbidity. Patients' perceptions of symptom interplay and treatment issues. J Subst Abuse Treat 15:445-448 (Pubitemid 28409327)
8. Cappell H, Herman CP (1972) Alcohol and tension reduction: A review. Q J Stud Alcohol 33:33-64
9. Colombo G, Agabio R, Lobina C, Reali R, Zocchi A, Fadda F, Gessa GL (1995) Sardinian alcohol-preferring rats: A genetic animal model of anxiety. Physiol Behav 57:1181-1185
10. Conger JJ (1956) Alcoholism: Theory, problem and challenge II. Reinforcement theory and the dynamics of alcoholism. Q J Stud Alcohol 17:296-305
11. Correia D, Ribeiro AF, Brunialti Godard AL, Boerngen-Lacerda R (2009) Trait anxiety and ethanol: Anxiolysis in high-anxiety mice and no relation to intake behavior in an addiction model. Prog Neuropsychopharmacol Biol Psychiatry 33:880-888
12. Costall B, Kelly ME, Naylor RJ (1988) The anxiolytic and anxiogenic actions of ethanol in a mousemodel. J Pharm Pharmacol 40:197-202
13. Crabbe JC, Phillips TJ, Kosobud A, Belknap JK (1990) Estimation of genetic correlation: Interpretation of experiments using selectively bred and inbred animals. Alcohol Clin Exp Res 14:141-151 (Pubitemid 20153355)
14. Croissant B, Olbrich R (2004) Stress response dampening indexed by cortisol in subjects at risk for alcoholism. J Stud Alcohol 65:701-707 (Pubitemid 40096932)
15. Curtin JJ, Lang AR, Patrick CJ, Stritzke WG (1998) Alcohol and fearpotentiated startle: The role of competing cognitive demands in the stress-reducing effects of intoxication. J Abnorm Psychol 107:547-557 (Pubitemid 28527568)
16. Davidson JR, Kudler HS, Saunders WB, Smith RD (1990) Symptom and comorbidity patterns in World War II and Vietnam veterans with posttraumatic stress disorder. Compr Psychiatry 31:162-170 (Pubitemid 20139627)
17. Davis M (1979) Diazepam and flurazepam: Effects on conditioned fear as measured with the potentiated startle paradigm. Psychopharmacology 62:1-7 (Pubitemid 10226227)
18. Davis M (2006) Neural systems involved in fear and anxiety measured with fear-potentiated startle. Am Psychol 61:741-756 (Pubitemid 44789942)
19. Durcan MJ, Lister RG (1988) Time course of ethanol's effects on locomotor activity, exploration and anxiety in mice. Psychopharmacology (Berl) 96:67-72
20. Fendt M, Fanselow MS (1999) The neuroanatomical and neurochemical basis of conditioned fear. Neurosci Biobehav Rev 23:743-760 (Pubitemid 29282023)
21. File SE (1976) Are central cholinergic paths involved in habituation of exploration and distraction? Pharmacol Biochem Behav 4:695-702
22. File SE, Hyde J, Pool M (1976) Effects of ethanol and chlordiazepoxide on social interaction in rats [proceedings]. Br J Pharmacol 58:465
23. Finn PR, Pihl RO (1987) Men at high risk for alcoholism: The effect of alcohol on cardiovascular response to unavoidable shock. J Abnorm Psychol 93:230-236
24. Gould TJ (2003) Ethanol disrupts fear conditioning in C57BL/6 mice. J Psychopharmacol 17:77-81 (Pubitemid 36373143)
25. Grahame NJ, Li TK, Lumeng L (1999) Limited access alcohol drinking in high-and low-alcohol preferring selected lines of mice. Alcohol Clin Exp Res 23:1015-1022 (Pubitemid 29283496)
26. Grahame NJ, Rodd-Henricks K, Li TK, Lumeng L (2000) Ethanol locomotor sensitization, but not tolerance correlates with selection for alcohol preference in high-and low-alcohol preferring mice. Psychopharmacology (Berl) 151:252-260 (Pubitemid 30646429)
27. Grillon C (2002) Startle reactivity and anxiety disorders: Aversive conditioning, context and neurobiology. Biol Psychiatry 52:958-975 (Pubitemid 35356354)
28. Gulick D, Gould TJ (2007) Acute ethanol has biphasic effects on short-and long-term memory in both foreground and background contextual fear conditioning in C57BL/6 mice. Alcohol Clin Exp Res 31:1528-1537 (Pubitemid 47319666)
29. Gulick D, Gould TJ (2009a) Effects of ethanol and caffeine on behavior in C57BL/6 mice in the plus-maze discriminative avoidance task. Behav Neurosci 123:1271-1278
30. Gulick D, Gould TJ (2009b) Interactive effects of ethanol and nicotine on learning, anxiety, and locomotion in C57BL/6 mice in the plus-maze discriminative avoidance task. Neuropsychopharmacology 57:302-310
31. Hijzen TH, Houtzager SW, Joordens RJ, Olivier B, Slangen JL (1995) Predictive validity of the potentiated startle response as a behavioral model for anxiolytic drugs. Psychopharmacology (Berl) 118:150-154
32. Himle JA, Abelson JL, Haghightgou H, Hill EM, Nesse RM, Curtis GC (1999) Effect of alcohol on social phobic anxiety. Am J Psychiatry 156:1237-1243 (Pubitemid 29374885)
33. Hoge CW, Castro CA, Messer SC, McGurk D, Cotting DI, Koffman RL (2004) Combat duty in Iraq and Afghanistan, mental health problems, and barriers to care. N Engl J Med 351:13-22 (Pubitemid 38857243)
34. Kameda SR, Frussa-Filho R, Carvalho RC, Takatsu-Coleman AL, Ricardo VP, Patti CL et al (2007) Dissociation of the effects of ethanol on memory, anxiety, and motor behavior in mice tested in the plus-maze discriminative avoidance task. Psychopharmacology (Berl) 192:39-48 (Pubitemid 46673888)
35. Kang HK, Hyams KC (2005) Mental health care needs among recent war veterans. N Engl J Med 352:1289 (Pubitemid 40411494)
36. Kessler RC, Nelson CB, McGonagle KA, Edlund MJ, Frank RG, Leaf PJ (1996) The epidemiology of co-occurring addictive and mental disorders: Implications for prevention and service utilization. Am J Orthopsychiatry 66:17-31 (Pubitemid 26031236)
37. Kim JJ, Jung MW (2006) Neural circuits and mechanisms involved in Pavlovian fear conditioning: A critical review. Neurosci Biobehav Rev 30:188-202 (Pubitemid 41821808)
38. Kolb LC (1984) The post-traumatic stress disorders of combat: A subgroup with a conditioned emotional response. Mil Med 149:237-243
39. LaBuda CJ, Fuchs PN (2002) Catecholamine depletion by reserpine blocks the anxiolytic actions of ethanol in the rat. Alcohol 26:55-59 (Pubitemid 34219005)
40. Land C, Spear NE (2004) Fear conditioning is impaired in adult rats by ethanol doses that do not affect periadolescents. Int J Dev Neurosci 22:355-362 (Pubitemid 39233543)
41. Lattal KM (2007) Effects of ethanol on the encoding, consolidation, and expression of extinction following contextual fear conditioning. Behav Neurosci 121:1280-1292
42. Levenson RW, Sher KJ, Grossman LM, Newman J, Newlin DB (1980) Alcohol and stress response dampening: Pharmacological effects, expectancy, and tension-reduction. J Abnorm Psychol 89:528-538 (Pubitemid 11246139)
43. Levenson RW, Oyama ON, Meek PS (1987) Greater reinforcement from alcohol for those at risk: Parental risk, personality risk, and sex. J Abnorm Psychol 96:242-253
44. Logue SF, Paylor R, Wehner JM (1997) Hippocampal lesions cause learning deficits in inbred mice in the Morris water maze and conditioned-fear task. Behav Neurosci 111:104-113 (Pubitemid 27097521)
45. Löw K, Crestani F, Keist R, Benke D, Brunig I, Benson JA et al (2000) Molecular and neuronal substrate for the selective attenuation of anxiety. Science 290:131-134
46. Maier W, Minges J, Lichtermann D (1993) Alcoholism and panic disorder: Co-occurrence and co-transmission in families. Eur Arch Psychiatry Clin Neurosci 243:205-211 (Pubitemid 24010909)
47. McBride WJ (2002) Central nucleus of the amygdala and the effects of alcohol and alcohol-drinking behavior in rodents. Pharmacol Biochem Behav 71:509-515 (Pubitemid 34117719)
48. McDougle CJ, Krystal JH, Price LH, Heninger GR, Charney DS (1995) Noradrenergic response to acute ethanol administration in healthy subjects: Comparison with intravenous yohimbine. Psychopharmacology (Berl) 118:127-135
49. McFarlane AC (1998) Epidemiological evidence about the relationship between PTSD and alcohol abuse: The nature of the association. Addict Behav 23:813-825 (Pubitemid 28443194)
50. McKinzie DL, Sajdyk TJ, McBride WJ, Murphy JM, Lumeng L, Li TK, Shekhar A (2000) Acoustic startle and fear-potentiated startle in alcohol-preferring (P) and -nonpreferring (NP) lines of rats. Pharmacol Biochem Behav 65:691-696 (Pubitemid 30182514)
51. Melia KR, Ryabinin AE, Corodimas KP, Wilson MC, Ledoux JE (1996) Hippocampal-dependent learning and experiencedependent activation of the hippocampus are preferentially disrupted by ethanol. Neuroscience 74:313-322 (Pubitemid 26274203)
52. Merikangas KR, Risch NJ, Weissman MM (1994) Comorbidity and co-transmission of alcoholism, anxiety and depression. Psychol Med 24:69-80 (Pubitemid 24083683)
53. Merikangas KR, Stevens DE, Fenton B, Stolar M, O'Malley S, Woods SW, Risch N (1998) Co-morbidity and familial aggregation of alcoholism and anxiety disorders. Psychol Med 28:773-788 (Pubitemid 28393558)
54. Miller NE, Barry H 3rd (1960) Motivational effects of drugs: Methods which illustrate some general problems in psychopharmacology. Psychopharmacologia 1:169-199
55. Milliken CS, Auchterlonie JL, Hoge CW (2007) Longitudinal assessment of mental health problems among active and reserve component soldiers returning from the Iraq war. JAMA 298:2141-2148 (Pubitemid 350106652)
56. Moberg CA, Curtin JJ (2009) Alcohol selectively reduces anxiety but not fear: Startle response during unpredictable versus predictable threat. J Abnorm Psychol 118:335-347
57. Munjack DJ, Moss HB (1981) Affective disorder and alcoholism in families of agoraphobics. Arch Gen Psychiatry 38:869-871 (Pubitemid 11040131)
58. Naftolowitz DF, Vaughn BV, Ranc J, Tancer ME (1994) Response to alcohol in social phobia. Anxiety 1:96-99
59. Nesic J, Duka T (2006) Gender specific effects of a mild stressor on alcohol cue reactivity in heavy social drinkers. Pharmacol Biochem Behav 83:239-248
60. Pandey SC, Zhang H, Roy A (2005) Deficits in amygdaloid cAMPresponsive element-binding protein signaling play a role in genetic predisposition to anxiety and alcoholism. J Clin Invest 115:2762-2773 (Pubitemid 41434403)
61. Phillips RG, LeDoux JE (1992) Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav Neurosci 106:274-285
62. Risbrough VB, Brodkin JD, Geyer MA (2003) GABA-A and 5HT1A receptor agonists block expression of fear-potentiated startle in mice. Neuropsychopharmacology 25:654-663
63. Roberto M, Madamba SG, Moore SD, Tallent MK, Siggins GR (2003) Ethanol increases GABAergic transmission at both pre-and postsynaptic sites in rat central amygdala neurons. Proc Natl Acad Sci USA 100:2053-2058 (Pubitemid 36254572)
64. Rorick LM, Finn PR, Steinmetz JE (2003) Moderate doses of ethanol partially reverse avoidance learning deficits in high-alcoholdrinking rats. Pharmacol Biochem Behav 75:89-102 (Pubitemid 36577584)
65. Ryabinin AE, Criado JR, Henriksen SJ, Bloom FE, Wilson MC (1997) Differential sensitivity of c-Fos expression in hippocampus and other brain regions to moderate and low doses of alcohol. Mol Psychiatry 2:32-43 (Pubitemid 27163109)
66. Sayette MA, Contrada RJ, Wilson GT (1990) Alcohol and correspondence between self-report and physiological measures of anxiety. Behav Res Ther 28:351-354 (Pubitemid 20283372)
67. Schuckit MA, Engstrom D, Alpert R, Duby J (1981) Differences in muscle-tension response to ethanol in young men with and without family histories of alcoholism. J Stud Alcohol 42:918-924 (Pubitemid 12151900)
68. Sher KJ (1987) Stress response dampening. In: Blane HT, Leonard KE (eds) Psychological Theories of Drinking and Alcoholism. Guilford Press, New York
69. Sinha R, Robinson J, O'Malley S (1998) Stress response dampening: Effects of gender and family history of alcoholism and anxiety disorders. Psychopharmacology (Berl) 137:311-320 (Pubitemid 28305365)
70. Smith KS, Meloni EG, Myers KM, Van't Veer A, Carlezon WA Jr, Rudolph U (2011) Reduction of fear-potentiated startle by benzodiazepines in C57BL/6J mice. Psychopharmacology (Berl) 213:697-706
71. Spanagel R, Montkowski A, Allingham K, Stohr T, Shoaib M, Holsboer F et al (1995) Anxiety: A potential predictor of vulnerability to the initiation of ethanol self administration in rats. Psychopharmacology 122:373
72. Stewart SH (1996) Alcohol abuse in individuals exposed to trauma: A critical review. Psychol Bull 120:83-112 (Pubitemid 126447650)
73. Stewart SH, Finn PR, Pihl RO (1992) The effects of alcohol on the cardiovascular stress response in men at high risk for alcoholism: A dose response study. J Stud Alcohol 53:499-506
74. Stewart RB, Gatto GJ, Lumeng L, Li TK, Murphy JM (1993) Comparison of alcohol-preferring (P) and nonpreferring (NP) rats on tests of anxiety and for the anxiolytic effects of ethanol. Alcohol 10:1-10 (Pubitemid 23062791)
75. Stromberg MF, Hammond LJ (1997) The effects of ethanol on a measure of conditioned fear in mice. Alcohol 14:403-407 (Pubitemid 27274740)
76. Terra MB, Figueira I, Barros HM (2004) Impact of alcohol intoxication and withdrawal syndrome on social phobia and panic disorder in alcoholic inpatients. Rev Hosp Clin Fac Med Sao Paulo 59:187-192
77. Thomas SE, Randall CL, Carrigan MH (2003) Drinking to cope in socially anxious individuals: A controlled study. Alcohol Clin Exp Res 27:1937-1943 (Pubitemid 38005062)
78. Walker DL, Davis M (2002) Quantifying fear potentiated startle using absolute versus proportional increase scoring methods: Implications for the neurocircuitry of fear and anxiety. Psychopharmacology (Berl) 164:318-328 (Pubitemid 35340999)
79. Wehner JM, Keller JJ, Keller AB, Picciotto MR, Paylor R, Booker TK, Beaudet A, Heinemann SF, Balogh SA (2004) Role of neuronal nicotinic receptors in the effects of nicotine and ethanol on contextual fear conditioning. Neuroscience 129:11-24 (Pubitemid 39360937)
80. Weiss KJ, Rosenberg DJ (1985) Prevalence of anxiety disorder among alcoholics. J Clin Psychiatry 46:3-5 (Pubitemid 15156255)
81. Weitemier AZ, Ryabinin AE (2003) Alcohol-induced memory impairment in trace fear conditioning: A hippocampus-specific effect. Hippocampus 13:305-315 (Pubitemid 36546764)
82. Zack M, Poulos CX, Aramakis VB, Khamba BK, MacLeod CM (2007) Effects of drink-stress sequence and gender on alcohol stress response dampening in high and low anxiety sensitive drinkers. Alcohol Clin Exp Res 31:411-422 (Pubitemid 46239273)
83. Zimmermann U, Spring K, Wittchen HU, Holsboer F (2004) Effects of ethanol administration and induction of anxiety-related affective states on the acoustic startle reflex in sons of alcoholdependent fathers. Alcoholism Clin Exp Res 28:424-432 (Pubitemid 38380745)
84. Zimmermann US, Buchmann AF, Spring C, Uhr M, Holsboer F, Wittchen HU (2009) Ethanol administration dampens the prolactin response to psychosocial stress exposure in sons of alcohol-dependent fathers. Psychoneuroendocrinology 34:996-1003