How the mitochondrion was shaped by radical differences in substrates: What carnitine shuttles and uncoupling tell us about mitochondrial evolution in response to ROS Insights & Perspectives D. Speijer

BioEssays

Volumn 36, Issue 7, 2014, Pages 634-643

  Speijer, Dave ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Beta oxidation; Carnitine shuttle; Mitochondria; Oxygen radicals; Peroxisomes; UCPs

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CARNITINE; FAS LIGAND; FATTY ACID; KETONE BODY; LACTIC ACID; OXYGEN RADICAL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCOUPLING PROTEIN; FREE RADICAL;

ALPHAPROTEOBACTERIA; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN; BREATHING; CATABOLISM; CITRIC ACID CYCLE; ELECTRON; ELECTRON TRANSPORT; EUKARYOTE EVOLUTION; FATTY ACID OXIDATION; GLYCOLYSIS; KINETICS; LIPID PEROXIDATION; LIPID STORAGE; METABOLISM; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOLECULAR EVOLUTION; NERVE CELL; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; OXIDATIVE STRESS; PEROXISOME; PRESSURE; PROKARYOTE; PROTEIN DEGRADATION; RESPIRATORY CHAIN; SYMBIONT; UPREGULATION; ANIMAL; EVOLUTION; HUMAN; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ALPHAPROTEOBACTERIA; ARCHAEA; EUKARYOTA; PROTEOBACTERIA;

ANIMALS; BIOLOGICAL EVOLUTION; BIOLOGICAL TRANSPORT; CARNITINE; FREE RADICALS; HUMANS; METABOLIC NETWORKS AND PATHWAYS; MITOCHONDRIA; REACTIVE OXYGEN SPECIES;

EID: 84901945229     PISSN: 02659247     EISSN: 15211878     Source Type: Journal    
DOI: 10.1002/bies.201400033     Document Type: Article

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