Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension

Circulation Research

Volumn 105, Issue 9, 2009, Pages 886-896

  Chan, Samuel H H ^a   Wu, Chiung Ai ^b   Wu, Kay L H ^b   Ho, Ying Hao ^b   Chang, Alice Y W ^a   Chan, Julie Y H ^b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Blood pressure; Mitochondrion; Oxidative stress; Peroxisome proliferator activated receptor; Uncoupling proteins

Indexed keywords

HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN 2; 2,4 THIAZOLIDINEDIONE DERIVATIVE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ADENOSINE TRIPHOSPHATE; AMINE OXIDE; ANGIOTENSIN II; ANTIOXIDANT; CATALASE; CATION; COPPER ZINC SUPEROXIDE DISMUTASE; DIPHENYLIODONIUM SALT; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; ION CHANNEL; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 2; PPARGC1A PROTEIN, RAT; PYRIDINE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RNA BINDING PROTEIN; ROSIGLITAZONE; SUPEROXIDE; SUPEROXIDE DISMUTASE; TEMPOL; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; FEEDBACK SYSTEM; HYPERTENSION; MALE; MEDULLA OBLONGATA; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; RAT; ROSTRAL VENTROLATERAL MEDULLA; SYMPATHETIC NERVE CELL; TRANSCRIPTION REGULATION; ADRENERGIC SYSTEM; ANIMAL; BLOOD PRESSURE; BLOOD VESSEL; CELL RESPIRATION; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; GENETIC TRANSDUCTION; GENETICS; HOMEOSTASIS; HUMAN; INNERVATION; METABOLISM; MICROINJECTION; MITOCHONDRION; PATHOPHYSIOLOGY; PHOSPHORYLATION; SPIN LABELING; SPRAGUE DAWLEY RAT; TIME; TRANSCRIPTION INITIATION; UPREGULATION;

ADENOSINE TRIPHOSPHATE; ANGIOTENSIN II; ANIMALS; ANTIOXIDANTS; BLOOD PRESSURE; BLOOD VESSELS; CATALASE; CELL RESPIRATION; CYCLIC N-OXIDES; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; HOMEOSTASIS; HUMANS; HYDROGEN PEROXIDE; HYPERTENSION; IMIDAZOLES; ION CHANNELS; MALE; MEDULLA OBLONGATA; MICROINJECTIONS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NADPH OXIDASE; ONIUM COMPOUNDS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PPAR GAMMA; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RNA-BINDING PROTEINS; SPIN LABELS; SUPEROXIDE DISMUTASE; SUPEROXIDES; SYMPATHETIC NERVOUS SYSTEM; THIAZOLIDINEDIONES; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; TRANSDUCTION, GENETIC; UP-REGULATION;

EID: 70350708314     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.199018     Document Type: Article

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