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Volumn 1831, Issue 9, 2013, Pages 1467-1474

Peroxisomes contribute to the acylcarnitine production when the carnitine shuttle is deficient

Author keywords

Carnitine palmitoyltransferase 1; Carnitine palmitoyltransferase 2; Carnitine acylcarnitine translocase; Fatty acid oxidation; Medium chain fatty acids; Mitochondria

Indexed keywords

ACYLCARNITINE; CARNITINE; CATALASE; LAURIC ACID; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; MEDIUM CHAIN FATTY ACID;

EID: 84884853475     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2013.06.007     Document Type: Article
Times cited : (72)

References (37)
  • 1
    • 77957608608 scopus 로고    scopus 로고
    • A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation
    • S.M. Houten, R.J. Wanders, A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation, J. Inherit. Metab. Dis. 33 (2010) 469-477.
    • (2010) J. Inherit. Metab. Dis. , vol.33 , pp. 469-477
    • Houten, S.M.1    Wanders, R.J.2
  • 2
    • 84870473233 scopus 로고    scopus 로고
    • Peroxisomes, peroxisomal diseases, and the hepatotoxicity induced by peroxisomal metabolites
    • R.J. Wanders, S. Ferdinandusse, Peroxisomes, peroxisomal diseases, and the hepatotoxicity induced by peroxisomal metabolites, Curr. Drug Metab. 13 (2012) 1401-1411.
    • (2012) Curr. Drug Metab. , vol.13 , pp. 1401-1411
    • Wanders, R.J.1    Ferdinandusse, S.2
  • 3
  • 4
    • 0036321931 scopus 로고    scopus 로고
    • Do long-chain acyl-CoA synthetases regulate fatty acid entry into synthetic versus degradative pathways?
    • R.A. Coleman, T.M. Lewin, C.G. Van Horn, M.R. Gonzalez-Baró, Do long-chain Acyl-CoA synthetases regulate fatty acid entry into synthetic versus degradative pathways? J. Nutr. 132 (2002) 2123-2126. (Pubitemid 34851637)
    • (2002) Journal of Nutrition , vol.132 , Issue.8 , pp. 2123-2126
    • Coleman, R.A.1    Lewin, T.M.2    Van Horn, C.G.3    Gonzalez-Baro, M.R.4
  • 5
    • 78651253382 scopus 로고    scopus 로고
    • Differential substrate specificities of human ABCD1 and ABCD2 in peroxisomal fatty acid β-oxidation
    • C.W.T. van Roermund, W.F. Visser, L. Ijlst, H.R. Waterham, R.J.A. Wanders, Differential substrate specificities of human ABCD1 and ABCD2 in peroxisomal fatty acid β-oxidation, Biochim. Biophys. Acta 1811 (2011) 148-152.
    • (2011) Biochim. Biophys. Acta , vol.1811 , pp. 148-152
    • Van Roermund, C.W.T.1    Visser, W.F.2    Ijlst, L.3    Waterham, H.R.4    Wanders, R.J.A.5
  • 6
    • 84864052256 scopus 로고    scopus 로고
    • Peroxisomal ABC transporters: Structure, function and role in disease
    • M. Morita, T. Imanaka, Peroxisomal ABC transporters: structure, function and role in disease, Biochim. Biophys. Acta 1822 (2012) 1387-1396.
    • (2012) Biochim. Biophys. Acta , vol.1822 , pp. 1387-1396
    • Morita, M.1    Imanaka, T.2
  • 7
  • 8
    • 0017805412 scopus 로고
    • Rat liver peroxisomes catalyze the beta oxidation of fatty acids
    • P.B. Lazarow, Rat liver peroxisomes catalyze the beta oxidation of fatty acids, J. Biol. Chem. 253 (1978) 1522-1528. (Pubitemid 8303455)
    • (1978) Journal of Biological Chemistry , vol.253 , Issue.5 , pp. 1522-1528
    • Lazarow, P.B.1
  • 9
    • 0021024932 scopus 로고
    • Carnitine-metabolismand functions
    • J. Bremer, Carnitine-metabolismand functions, Physiol. Rev. 63 (1983) 1420-1480.
    • (1983) Physiol. Rev. , vol.63 , pp. 1420-1480
    • Bremer, J.1
  • 11
    • 0025818442 scopus 로고
    • Utilization of medium-chain triglycerides by neonatal piglets: Chain length of even-and odd-carbon fatty acids and apparent digestion/absorption and hepatic metabolism
    • J. Odle, N.J. Benevenga, T.D. Crenshaw, Utilization of medium-chain triglycerides by neonatal piglets: chain length of even-and odd-carbon fatty acids and apparent digestion/absorption and hepatic metabolism, J. Nutr. 121 (1991) 605-614.
    • (1991) J. Nutr. , vol.121 , pp. 605-614
    • Odle, J.1    Benevenga, N.J.2    Crenshaw, T.D.3
  • 12
    • 0028797234 scopus 로고
    • Carnitine affects octanoate oxidation to carbon dioxide and dicarboxylic acids in colostrum-deprived piglets: In vivo analysis ofmechanisms involved based on CoA-and carnitine-ester profiles
    • T.A. van Kempen, J. Odle, Carnitine affects octanoate oxidation to carbon dioxide and dicarboxylic acids in colostrum-deprived piglets: in vivo analysis ofmechanisms involved based on CoA-and carnitine-ester profiles, J. Nutr. 125 (1995) 238-250.
    • (1995) J. Nutr. , vol.125 , pp. 238-250
    • Van Kempen, T.A.1    Odle, J.2
  • 13
    • 0014272758 scopus 로고
    • Inhibition of fatty acid stimulation of gluconeogenesis by (+)-decanoylcarnitine in perfused rat liver
    • J.R. Williamson, E.T. Browning, R. Scholz, R.A. Kreisberg, I.B. Fritz, Inhibition of fatty acid stimulation of gluconeogenesis by (+)-decanoylcarnitine in perfused rat liver, Diabetes 17 (1968) 194-208.
    • (1968) Diabetes , vol.17 , pp. 194-208
    • Williamson, J.R.1    Browning, E.T.2    Scholz, R.3    Kreisberg, R.A.4    Fritz, I.B.5
  • 14
    • 0014426846 scopus 로고
    • Short-chain fatty acid activation in rat liver a newassay procedure for the enzymes and studies on their intracellular localization
    • M. Aas, J. Bremer, Short-chain fatty acid activation in rat liver a newassay procedure for the enzymes and studies on their intracellular localization, Biochim. Biophys. Acta 164 (1968) 157-166.
    • (1968) Biochim. Biophys. Acta , vol.164 , pp. 157-166
    • Aas, M.1    Bremer, J.2
  • 17
    • 0015852493 scopus 로고
    • The activation and oxidation of octanoate and palmitate by rat skeletal muscle mitochondria
    • P.H.E. Groot, W.C. Hülsmann, The activation and oxidation of octanoate and palmitate by rat skeletal muscle mitochondria, Biochim. Biophys. Acta 316 (1973) 124-135.
    • (1973) Biochim. Biophys. Acta , vol.316 , pp. 124-135
    • Groot, P.H.E.1    Hülsmann, W.C.2
  • 18
    • 0021333872 scopus 로고
    • Relationship of the ATP/ADP ratio to the site of octanoate activation
    • D.A. Otto, Relationship of the ATP/ADP ratio to the site of octanoate activation, J. Biol. Chem. 259 (1984) 5490-5494. (Pubitemid 14145003)
    • (1984) Journal of Biological Chemistry , vol.259 , Issue.9 , pp. 5490-5494
    • Otto, D.A.1
  • 19
    • 0027220217 scopus 로고
    • Medium-chain fatty acid oxidation in colostrum-deprived newborn piglets: Stimulative effect of L-carnitine supplementation
    • T.A. van Kempen, J. Odle, Medium-chain fatty acid oxidation in colostrum-deprived newborn piglets: stimulative effect of L-carnitine supplementation, J. Nutr. 123 (1993) 1531-1537. (Pubitemid 23268005)
    • (1993) Journal of Nutrition , vol.123 , Issue.9 , pp. 1531-1537
    • Van Kempen, T.A.T.G.1    Odle, J.2
  • 20
    • 0025133042 scopus 로고
    • Role of carnitine in utilization of dietary medium-chain triglycerides by term infants
    • C.J. Rebouche, D.D. Panagides, S.E. Nelson, Role of carnitine in utilization of dietary medium-chain triglycerides by term infants, Am. J. Clin. Nutr. 52 (1990) 820-824.
    • (1990) Am. J. Clin. Nutr. , vol.52 , pp. 820-824
    • Rebouche, C.J.1    Panagides, D.D.2    Nelson, S.E.3
  • 22
    • 0026483753 scopus 로고
    • Quantification of carnitine esters by high-performance liquid chromatography. Effect of feeding medium-chain triglycerides on the plasma carnitine ester profile
    • T.A. van Kempen, J. Odle, Quantification of carnitine esters by high-performance liquid chromatography. Effect of feeding medium-chain triglycerides on the plasma carnitine ester profile, J. Chromatogr. 584 (1992) 157-165.
    • (1992) J. Chromatogr. , vol.584 , pp. 157-165
    • Van Kempen, T.A.1    Odle, J.2
  • 26
    • 0022186670 scopus 로고
    • Measurement of protein using bicinchoninic acid
    • DOI 10.1016/0003-2697(85)90442-7
    • P.K. Smith, R.I. Krohn, G.T. Hermanson, A.K. Mallia, F.H. Gartner, M.D. Provenzano, E.K. Fujimoto, N.M. Goeke, B.J. Olson, D.C. Klenk, Measurement of protein using bicinchoninic acid, Anal. Biochem. 150 (1985) 76-85. (Pubitemid 16258399)
    • (1985) Analytical Biochemistry , vol.150 , Issue.1 , pp. 76-85
    • Smith, P.K.1    Krohn, R.I.2    Hermanson, G.T.3
  • 27
    • 0033001744 scopus 로고    scopus 로고
    • Quantitative plasma acylcarnitine analysis using electrospray tandem mass spectrometry for the diagnosis of organic acidaemias and fatty acid oxidation defects
    • DOI 10.1023/A:1005587617745
    • P. Vreken, A.E.M. van Lint, A.H. Bootsma, H. Overmars, R.J.A. Wanders, A.H. van Gennip, Quantitative plasma acylcarnitine analysis using electrospray tandem mass spectrometry for the diagnosis of organic acidaemias and fatty acid oxidation defects, J. Inherit. Metab. Dis. 22 (1999) 302-306. (Pubitemid 29259500)
    • (1999) Journal of Inherited Metabolic Disease , vol.22 , Issue.3 , pp. 302-306
    • Vreken, P.1    Van Lint, A.E.M.2    Bootsma, A.H.3    Overmars, H.4    Wanders, R.J.A.5    Van Gennip, A.H.6
  • 28
    • 84864029381 scopus 로고    scopus 로고
    • Genetics and molecular basis of human peroxisome biogenesis disorders
    • H.R. Waterham, M.S. Ebberink, Genetics and molecular basis of human peroxisome biogenesis disorders, Biochim. Biophys. Acta 1822 (2012) 1430-1441.
    • (2012) Biochim. Biophys. Acta , vol.1822 , pp. 1430-1441
    • Waterham, H.R.1    Ebberink, M.S.2
  • 30
    • 0022345034 scopus 로고
    • DL-aminocarnitine and acetyl-DL-aminocarnitine. Potent inhibitors of carnitine acyltransferases and hepatic triglyceride catabolism
    • D.L. Jenkins, O.W. Griffith, DL-aminocarnitine and acetyl-DL- aminocarnitine. Potent inhibitors of carnitine acyltransferases and hepatic triglyceride catabolism, J. Biol. Chem. 260 (1985) 14748-14755.
    • (1985) J. Biol. Chem. , vol.260 , pp. 14748-14755
    • Jenkins, D.L.1    Griffith, O.W.2
  • 31
    • 84877125588 scopus 로고    scopus 로고
    • Carnitine palmitoyltransferase 2 and carnitine/acylcarnitine translocase are involved in the mitochondrial synthesis and export of acylcarnitines
    • S. Violante, L. IJlst, H. teBrinke, I. Tavares deAlmeida, R.J.A. Wanders, F.V. Ventura, S.M. Houten, Carnitine palmitoyltransferase 2 and carnitine/acylcarnitine translocase are involved in the mitochondrial synthesis and export of acylcarnitines, FASEB J. 27 (2013) 2039-2044.
    • (2013) FASEB J. , vol.27 , pp. 2039-2044
    • Violante, S.1    Ijlst, L.2    Tebrinke, H.3    Tavares Dealmeida, I.4    Wanders, R.J.A.5    Ventura, F.V.6    Houten, S.M.7
  • 32
    • 78651082310 scopus 로고    scopus 로고
    • Fatty acid omega-oxidation as a rescue pathway for fatty acid oxidation disorders in humans
    • R.J.A. Wanders, J. Komen, S. Kemp, Fatty acid omega-oxidation as a rescue pathway for fatty acid oxidation disorders in humans, FEBS J. 278 (2011) 182-194.
    • (2011) FEBS J. , vol.278 , pp. 182-194
    • Wanders, R.J.A.1    Komen, J.2    Kemp, S.3
  • 33
    • 84862333931 scopus 로고    scopus 로고
    • Peroxisomal L-bifunctional enzyme (Ehhadh) is essential for the production of medium-chain dicarboxylic acids
    • S.M. Houten, S. Denis, C.A. Argmann, Y. Jia, S. Ferdinandusse, J.K. Reddy, R.J.A. Wanders, Peroxisomal L-bifunctional enzyme (Ehhadh) is essential for the production of medium-chain dicarboxylic acids, J. Lipid Res. 53 (2012) 1296-1303.
    • (2012) J. Lipid Res. , vol.53 , pp. 1296-1303
    • Houten, S.M.1    Denis, S.2    Argmann, C.A.3    Jia, Y.4    Ferdinandusse, S.5    Reddy, J.K.6    Wanders, R.J.A.7
  • 34
    • 0015211317 scopus 로고
    • The separation and properties of two forms of carnitine palmitoyltransferase from ox liver mitochondria
    • D.W. West, J.F.A. Chase, P.K. Tubbs, The separation and properties of two forms of carnitine palmitoyltransferase from ox liver mitochondria, Biochem. Biophys. Res. Commun. 42 (1971) 912-918.
    • (1971) Biochem. Biophys. Res. Commun. , vol.42 , pp. 912-918
    • West, D.W.1    Chase, J.F.A.2    Tubbs, P.K.3
  • 35
    • 0020612889 scopus 로고
    • Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver
    • S. Miyazawa, H. Ozasa, T. Osumi, T. Hashimoto, Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver, J. Biochem. 94 (1983) 529-542. (Pubitemid 13018950)
    • (1983) Journal of Biochemistry , vol.94 , Issue.2 , pp. 529-542
    • Miyazawa, S.1    Ozasa, H.2    Osumi, T.3    Hashimoto, T.4


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