Bufalin induces cell death in human lung cancer cells through disruption of DNA damage response pathways

American Journal of Chinese Medicine

Volumn 42, Issue 3, 2014, Pages 729-742

  Wu, Shin Hwar ^a,b   Wu, Tzu Yun ^a   Hsiao, Yung Ting ^a   Lin, Ju Hwa ^a   Hsu, Shu Chun ^a   Hsia, Te Chun ^a,c   Yang, Su Tso ^c   Hsu, Wu Huei ^c   Chung, Jing Gung ^a,d  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d ASIA UNIVERSITY   (Taiwan)

Author keywords

Bufalin; DNA Damage; Human Lung Cancer NCI H460 Cells

Indexed keywords

ATM PROTEIN; ATR PROTEIN; BRCA1 PROTEIN; BUFALIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN MDC1; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; REGULATOR PROTEIN; STRATIFIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BRCA1 PROTEIN, HUMAN; BUFADIENOLIDE DERIVATIVE; CHAN SU; DNA DEPENDENT PROTEIN KINASE; DNA METHYLTRANSFERASE; EXORIBONUCLEASE; MDC1 PROTEIN, HUMAN; MGMT PROTEIN, HUMAN; NUCLEAR PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN 14 3 3; SFN PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL DESTRUCTION; CELL DEATH; CHINESE MEDICINE; CONTROLLED STUDY; DNA DAMAGE; DNA DAMAGE CHECKPOINT; DNA DAMAGE RESPONSE; DNA REPAIR; DRUG MECHANISM; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG CANCER; LUNG CANCER CELL LINE; MEDIATOR; DRUG EFFECTS; GENE; GENETICS; LUNG TUMOR; METABOLISM; PATHOLOGY; TUMOR CELL CULTURE;

14-3-3 PROTEINS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BRCA1 PROTEIN; BUFANOLIDES; DNA DAMAGE; DNA MODIFICATION METHYLASES; DNA REPAIR; DNA REPAIR ENZYMES; DNA-ACTIVATED PROTEIN KINASE; EXORIBONUCLEASES; GENES, CDC; HUMANS; LUNG NEOPLASMS; NUCLEAR PROTEINS; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84901807769     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X14500475     Document Type: Article

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