Bufalin induces lung cancer cell apoptosis via the inhibition of PI3K/Akt pathway

International Journal of Molecular Sciences

Volumn 13, Issue 2, 2012, Pages 2025-2035

  Zhu, Zhitu ^a   Sun, Hongzhi ^a   Ma, Guangyou ^a   Wang, Zhenghua ^a   Li, Enze ^a   Liu, Yangyang ^a   Liu, Yunpeng ^b  

^a JINZHOU MEDICAL UNIVERSITY   (China)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

A549 cells; Apoptosis; Bufalin; Lung cancer; PI3K Akt

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BUFALIN; CASPASE 3; LIVIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; ANTINEOPLASTIC AGENT; BUFADIENOLIDE DERIVATIVE; ONCOPROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CANCER INHIBITION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; FLOW CYTOMETRY; GIEMSA STAIN; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ADENOCARCINOMA; PROTEIN DETERMINATION; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING; ADENOCARCINOMA; CELL PROLIFERATION; DRUG EFFECTS; LUNG TUMOR; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; APOPTOSIS; BUFANOLIDES; CELL PROLIFERATION; DOWN-REGULATION; HUMANS; LUNG NEOPLASMS; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 84863269309     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13022025     Document Type: Article

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