Microsatellite stable colorectal cancers stratified by the BRAF V600E mutation show distinct patterns of chromosomal instability

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Bond, Catherine E ^a,b   Nancarrow, Derek J ^a   Wockner, Leesa F ^a   Wallace, Leanne ^a   Montgomery, Grant W ^a   Leggett, Barbara A ^a,b,c   Whitehall, Vicki L J ^a,d  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^d Oncogenomics Group QIMR Berghofer Medical Research Institute ^*  (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; K RAS PROTEIN; BRAF PROTEIN, HUMAN;

ARTICLE; BRAF GENE; CHROMOSOMAL INSTABILITY; CHROMOSOME 17P; CHROMOSOME 18Q; CHROMOSOME 1P; CHROMOSOME 22Q; CHROMOSOME 4Q; CHROMOSOME 5Q; CHROMOSOME ABERRATION; CHROMOSOME SIZE; COLORECTAL CANCER; CONTROLLED STUDY; CPG ISLAND; FEMALE; GENE AMPLIFICATION; GENE DOSAGE; GENE FREQUENCY; GENE MUTATION; GENETIC HETEROGENEITY; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; KRAS GENE; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; PATHOGENESIS; SINGLE NUCLEOTIDE POLYMORPHISM; AGED; AMINO ACID SUBSTITUTION; COHORT ANALYSIS; COLORECTAL TUMOR; COPY NUMBER VARIATION; GENE DELETION; GENETICS; HUMAN GENOME; MUTATION;

AGED; AMINO ACID SUBSTITUTION; CHROMOSOMAL INSTABILITY; COHORT STUDIES; COLORECTAL NEOPLASMS; DNA COPY NUMBER VARIATIONS; FEMALE; GENOME, HUMAN; HUMANS; MALE; MICROSATELLITE INSTABILITY; MUTATION; PROTO-ONCOGENE PROTEINS B-RAF; SEQUENCE DELETION;

EID: 84901786400     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091739     Document Type: Article

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