Anti-inflammatory and corticosteroid-enhancing actions of vitamin D in monocytes of patients with steroid-resistant and those with steroid-sensitive asthma

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 6, 2014, Pages

  Zhang, Yong ^a   Leung, Donald Y M ^a,b   Goleva, Elena ^a  

^a DEPARTMENT OF MEDICINE   (United States)

^b Children's Hospital Colorado   (United States)

Author keywords

Asthma; corticosteroids; steroid resistance; vitamin D

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCITRIOL; CORTICOSTEROID; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; HISTONE H4; LONG ACTING DRUG; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; VITAMIN D; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PREDNISONE;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; CELL LEVEL; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION ASSAY; HISTONE ACETYLATION; HUMAN; HUMAN CELL; MALE; MONOCYTE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR BINDING; STEROID RESISTANT ASTHMA; STEROID SENSITIVE ASTHMA; CYTOKINE PRODUCTION; HORMONE RESPONSE; IN VITRO STUDY; PROTEIN PHOSPHORYLATION;

ASTHMA; CORTICOSTEROIDS; STEROID RESISTANCE; VITAMIN D;

ACETYLATION; ADRENAL CORTEX HORMONES; ADULT; ANTI-INFLAMMATORY AGENTS; ASTHMA; DRUG RESISTANCE; DRUG SYNERGISM; DUAL SPECIFICITY PHOSPHATASE 1; FEMALE; HISTONES; HUMANS; INTERLEUKIN-6; MALE; MIDDLE AGED; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RECEPTORS, GLUCOCORTICOID; RESPIRATORY FUNCTION TESTS; RESPONSE ELEMENTS; VITAMIN D;

EID: 84901770303     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.12.004     Document Type: Article

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