Chronic ethanol exposure alters the lung proteome and leads to mitochondrial dysfunction in alveolar type 2 cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 306, Issue 11, 2014, Pages

  Alli, Abdel A ^a   Brewer, Elizabeth M ^a   Montgomery, Darrice S ^b   Ghant, Marcus S ^b   Eaton, Douglas C ^a   Brown, Lou Ann ^a   Helms, My N ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CLARK ATLANTA UNIVERSITY   (United States)

Author keywords

Chronic alcohol ingestion; ENaC; Gene chip array; Mass spectrometry; Mitochondrial stress

Indexed keywords

ALCOHOL; LIPOPOLYSACCHARIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PROTEOME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ADULT; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; LIQUID CHROMATOGRAPHY; LONG TERM EXPOSURE; LUNG ALVEOLUS CELL TYPE 2; LUNG INJURY; MALE; MASS SPECTROMETRY; MICROARRAY ANALYSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; RAT; TRANSMISSION ELECTRON MICROSCOPY; TWO DIMENSIONAL GEL ELECTROPHORESIS; YOUNG ADULT;

CHRONIC ALCOHOL INGESTION; ENAC; GENE CHIP ARRAY; MASS SPECTROMETRY; MITOCHONDRIAL STRESS;

ALCOHOLISM; ANIMALS; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; FEMALE; LIPOPOLYSACCHARIDES; LUNG; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MITOCHONDRIAL SWELLING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PNEUMOCYTES; PROTEOME; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTOME;

EID: 84901700372     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00287.2013     Document Type: Article

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