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Volumn 188, Issue 6, 2013, Pages 716-723

Alcoholism causes alveolar macrophage zinc deficiency and immune dysfunction

Author keywords

Alcohol abuse; Alveolar macrophage; Glutathione; Immunity; Zinc

Indexed keywords

GLUTATHIONE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; ZINC ACETATE;

EID: 84884647691     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201301-0061OC     Document Type: Article
Times cited : (70)

References (50)
  • 1
    • 70449406726 scopus 로고    scopus 로고
    • HHS Publication No. SMA 09-4434 ed. Rockville, MD: Substance Abuse and Mental Health Services Administration
    • Results from the 2008 national survey on drug use and health: national findings. HHS Publication No. SMA 09-4434 ed. Rockville, MD: Substance Abuse and Mental Health Services Administration; 2009.
    • (2009) Results from the 2008 National Survey on Drug use and Health: National Findings
  • 2
    • 48649109374 scopus 로고    scopus 로고
    • Secular trends in alcohol consumption over 50 years: The Framingham Study
    • Zhang Y, Guo X, Saitz R, Levy D, Sartini E, Niu J, Ellison RC. Secular trends in alcohol consumption over 50 years: the Framingham Study. Am J Med 2008;121:695-701.
    • (2008) Am J Med , vol.121 , pp. 695-701
    • Zhang, Y.1    Guo, X.2    Saitz, R.3    Levy, D.4    Sartini, E.5    Niu, J.6    Ellison, R.C.7
  • 3
  • 5
    • 68149110224 scopus 로고    scopus 로고
    • Procysteine stimulates expression of key anabolic factors and reduces plantaris atrophy in alcohol-fed rats
    • Otis JS, Guidot DM. Procysteine stimulates expression of key anabolic factors and reduces plantaris atrophy in alcohol-fed rats. Alcohol Clin Exp Res 2009;33:1450-1459.
    • (2009) Alcohol Clin Exp Res , vol.33 , pp. 1450-1459
    • Otis, J.S.1    Guidot, D.M.2
  • 6
    • 0028810725 scopus 로고
    • Medical disorders of alcoholism
    • Lieber CS. Medical disorders of alcoholism. N Engl J Med 1995;333:1058-1065.
    • (1995) N Engl J Med , vol.333 , pp. 1058-1065
    • Lieber, C.S.1
  • 7
    • 34247188485 scopus 로고    scopus 로고
    • The alcoholic lung: Epidemiology, pathophysiology, and potential therapies
    • Joshi PC, Guidot DM. The alcoholic lung: epidemiology, pathophysiology, and potential therapies. Am J Physiol Lung Cell Mol Physiol 2007;292:L813-L823.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.292
    • Joshi, P.C.1    Guidot, D.M.2
  • 8
    • 33646484932 scopus 로고    scopus 로고
    • Impact of alcohol abuse in the etiology and severity of community-acquired pneumonia
    • de Roux A, Cavalcanti M, Marcos MA, Garcia E, Ewig S, Mensa J, Torres A. Impact of alcohol abuse in the etiology and severity of community-acquired pneumonia. Chest 2006;129:1219-1225.
    • (2006) Chest , vol.129 , pp. 1219-1225
    • De Roux, A.1    Cavalcanti, M.2    Marcos, M.A.3    Garcia, E.4    Ewig, S.5    Mensa, J.6    Torres, A.7
  • 9
    • 0037350429 scopus 로고    scopus 로고
    • Chronic alcohol abuse is associated with an increased incidence of acute respiratory distress syndrome and severity of multiple organ dysfunction in patients with septic shock
    • Moss M, Parsons PE, Steinberg KP, Hudson LD, Guidot DM, Burnham EL, Eaton S, Cotsonis GA. Chronic alcohol abuse is associated with an increased incidence of acute respiratory distress syndrome and severity of multiple organ dysfunction in patients with septic shock. Crit Care Med 2003;31:869-877.
    • (2003) Crit Care Med , vol.31 , pp. 869-877
    • Moss, M.1    Parsons, P.E.2    Steinberg, K.P.3    Hudson, L.D.4    Guidot, D.M.5    Burnham, E.L.6    Eaton, S.7    Cotsonis, G.A.8
  • 13
    • 27744509832 scopus 로고    scopus 로고
    • Chronic ethanol ingestion in rats decreases granulocyte-macrophage colony-stimulating factor receptor expression and downstream signaling in the alveolar macrophage
    • Joshi PC, Applewhite L, Ritzenthaler JD, Roman J, Fernandez AL, Eaton DC, Brown LA, Guidot DM. Chronic ethanol ingestion in rats decreases granulocyte-macrophage colony-stimulating factor receptor expression and downstream signaling in the alveolar macrophage. J Immunol 2005;175:6837-6845.
    • (2005) J Immunol , vol.175 , pp. 6837-6845
    • Joshi, P.C.1    Applewhite, L.2    Ritzenthaler, J.D.3    Roman, J.4    Fernandez, A.L.5    Eaton, D.C.6    Brown, L.A.7    Guidot, D.M.8
  • 15
    • 0029923083 scopus 로고    scopus 로고
    • Alcohol modulates alveolar macrophage tumor necrosis factor-alpha, superoxide anion, and nitric oxide secretion in the rat
    • D'Souza NB, Nelson S, Summer WR, Deaciuc IV. Alcohol modulates alveolar macrophage tumor necrosis factor-alpha, superoxide anion, and nitric oxide secretion in the rat. Alcohol Clin Exp Res 1996;20:156-163.
    • (1996) Alcohol Clin Exp Res , vol.20 , pp. 156-163
    • D'Souza, N.B.1    Nelson, S.2    Summer, W.R.3    Deaciuc, I.V.4
  • 16
    • 0028799326 scopus 로고
    • Alcohol ingestion impairs host defenses predisposing otherwise healthy mice to Pneumocystis carinii infection
    • D'Souza NB, Mandujano JF, Nelson S, Summer WR, Shellito JE. Alcohol ingestion impairs host defenses predisposing otherwise healthy mice to Pneumocystis carinii infection. Alcohol Clin Exp Res 1995;19:1219-1225.
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 1219-1225
    • D'Souza, N.B.1    Mandujano, J.F.2    Nelson, S.3    Summer, W.R.4    Shellito, J.E.5
  • 18
    • 34547557025 scopus 로고    scopus 로고
    • Chronic alcoholism alters systemic and pulmonary glutathione redox status
    • Yeh MY, Burnham EL, Moss M, Brown LA. Chronic alcoholism alters systemic and pulmonary glutathione redox status. Am J Respir Crit Care Med 2007;176:270-276.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 270-276
    • Yeh, M.Y.1    Burnham, E.L.2    Moss, M.3    Brown, L.A.4
  • 20
    • 0036201268 scopus 로고    scopus 로고
    • GM-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense
    • Trapnell BC, Whitsett JA. GM-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense. Annu Rev Physiol 2002;64:775-802.
    • (2002) Annu Rev Physiol , vol.64 , pp. 775-802
    • Trapnell, B.C.1    Whitsett, J.A.2
  • 21
    • 79960641741 scopus 로고    scopus 로고
    • Zinc supplementation restores pu.1 and nrf2 nuclear binding in alveolar macrophages and improves redox balance and bacterial clearance in the lungs of alcohol-fed rats
    • Mehta AJ, Joshi PC, Fan X, Brown LA, Ritzenthaler JD, Roman J, Guidot DM. Zinc supplementation restores pu.1 and nrf2 nuclear binding in alveolar macrophages and improves redox balance and bacterial clearance in the lungs of alcohol-fed rats. Alcohol Clin Exp Res 2011;35:1519-1528.
    • (2011) Alcohol Clin Exp Res , vol.35 , pp. 1519-1528
    • Mehta, A.J.1    Joshi, P.C.2    Fan, X.3    Brown, L.A.4    Ritzenthaler, J.D.5    Roman, J.6    Guidot, D.M.7
  • 23
    • 0031014965 scopus 로고    scopus 로고
    • Zinc deficiency in young children
    • Hambidge KM. Zinc deficiency in young children. Am J Clin Nutr 1997;65:160-161.
    • (1997) Am J Clin Nutr , vol.65 , pp. 160-161
    • Hambidge, K.M.1
  • 24
    • 0017679911 scopus 로고
    • Nutritional zinc deficiency in infants and children
    • Walravens PA, Hambidge KM. Nutritional zinc deficiency in infants and children. Prog Clin Biol Res 1977;14:61-72.
    • (1977) Prog Clin Biol Res , vol.14 , pp. 61-72
    • Walravens, P.A.1    Hambidge, K.M.2
  • 25
    • 0037042640 scopus 로고    scopus 로고
    • Effect of routine zinc supplementation on pneumonia in children aged 6 months to 3 years: Randomised controlled trial in an urban slum
    • Bhandari N, Bahl R, Taneja S, Strand T, Molbak K, Ulvik RJ, Sommerfelt H, Bhan MK. Effect of routine zinc supplementation on pneumonia in children aged 6 months to 3 years: randomised controlled trial in an urban slum. BMJ 2002;324:1358.
    • (2002) BMJ , vol.324 , pp. 1358
    • Bhandari, N.1    Bahl, R.2    Taneja, S.3    Strand, T.4    Molbak, K.5    Ulvik, R.J.6    Sommerfelt, H.7    Bhan, M.K.8
  • 26
    • 0031803961 scopus 로고    scopus 로고
    • Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: A double-blind, controlled trial
    • Sazawal S, Black RE, Jalla S, Mazumdar S, Sinha A, Bhan MK. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial. Pediatrics 1998;102:1-5.
    • (1998) Pediatrics , vol.102 , pp. 1-5
    • Sazawal, S.1    Black, R.E.2    Jalla, S.3    Mazumdar, S.4    Sinha, A.5    Bhan, M.K.6
  • 27
    • 67651165172 scopus 로고    scopus 로고
    • Zinc deficiency mediates alcohol-induced alveolar epithelial and macrophage dysfunction in rats
    • Joshi PC, Mehta A, Jabber WS, Fan X, Guidot DM. Zinc deficiency mediates alcohol-induced alveolar epithelial and macrophage dysfunction in rats. Am J Respir Cell Mol Biol 2009;41:207-216.
    • (2009) Am J Respir Cell Mol Biol , vol.41 , pp. 207-216
    • Joshi, P.C.1    Mehta, A.2    Jabber, W.S.3    Fan, X.4    Guidot, D.M.5
  • 28
    • 84885475456 scopus 로고    scopus 로고
    • Zinc supplementation in vitro improves immune function and restores intracellular zinc levels in alveolar macrophages isolated from human alcoholics
    • Mehta AJ, Yeligar SM, Brown LA, Guidot DM. Zinc supplementation in vitro improves immune function and restores intracellular zinc levels in alveolar macrophages isolated from human alcoholics. Am J Respir Crit Care Med 2012;185:A1369.
    • (2012) Am J Respir Crit Care Med , vol.185
    • Mehta, A.J.1    Yeligar, S.M.2    Brown, L.A.3    Guidot, D.M.4
  • 29
    • 0016838147 scopus 로고
    • A Self-Administered Short Michigan Alcoholism Screening Test (SMAST)
    • Selzer ML, Vinokur A, van Rooijen L. A Self-Administered Short Michigan Alcoholism Screening Test (SMAST). J Stud Alcohol 1975;36:117-126.
    • (1975) J Stud Alcohol , vol.36 , pp. 117-126
    • Selzer, M.L.1    Vinokur, A.2    Van Rooijen, L.3
  • 30
    • 0027154845 scopus 로고
    • Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption-II
    • Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M. Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption-II. Addiction 1993;88:791-804.
    • (1993) Addiction , vol.88 , pp. 791-804
    • Saunders, J.B.1    Aasland, O.G.2    Babor, T.F.3    De La Fuente, J.R.4    Grant, M.5
  • 31
    • 0018601901 scopus 로고
    • Inflammatory and immune processes in the human lung in health and disease: Evaluation by bronchoalveolar lavage
    • Hunninghake GW, Gadek JE, Kawanami O, Ferrans VJ, Crystal RG. Inflammatory and immune processes in the human lung in health and disease: evaluation by bronchoalveolar lavage. Am J Pathol 1979;97:149-206.
    • (1979) Am J Pathol , vol.97 , pp. 149-206
    • Hunninghake, G.W.1    Gadek, J.E.2    Kawanami, O.3    Ferrans, V.J.4    Crystal, R.G.5
  • 32
    • 70349311757 scopus 로고    scopus 로고
    • Impaired terminal differentiation of pulmonary macrophages in a guinea pig model of chronic ethanol ingestion
    • Brown SD, Gauthier TW, Brown LA. Impaired terminal differentiation of pulmonary macrophages in a guinea pig model of chronic ethanol ingestion. Alcohol Clin Exp Res 2009;33:1782-1793.
    • (2009) Alcohol Clin Exp Res , vol.33 , pp. 1782-1793
    • Brown, S.D.1    Gauthier, T.W.2    Brown, L.A.3
  • 34
    • 0006325557 scopus 로고
    • One-step Huber estimates in the linear model
    • Bickel PJ. One-step Huber estimates in the linear model. J Am Stat Assoc 1975;70:428-434.
    • (1975) J Am Stat Assoc , vol.70 , pp. 428-434
    • Bickel, P.J.1
  • 35
    • 67650239640 scopus 로고    scopus 로고
    • Risk factors for complicated parapneumonic effusion and empyema on presentation to hospital with community-acquired pneumonia
    • Chalmers JD, Singanayagam A, Murray MP, Scally C, Fawzi A, Hill AT. Risk factors for complicated parapneumonic effusion and empyema on presentation to hospital with community-acquired pneumonia. Thorax 2009;64:592-597.
    • (2009) Thorax , vol.64 , pp. 592-597
    • Chalmers, J.D.1    Singanayagam, A.2    Murray, M.P.3    Scally, C.4    Fawzi, A.5    Hill, A.T.6
  • 36
    • 45149094751 scopus 로고    scopus 로고
    • At-risk drinkers are at higher risk to acquire a bacterial infection during an intensive care unit stay than abstinent or moderate drinkers
    • Gacouin A, Legay F, Camus C, Volatron AC, Barbarot N, Donnio PY, Thomas R, Le Tulzo Y. At-risk drinkers are at higher risk to acquire a bacterial infection during an intensive care unit stay than abstinent or moderate drinkers. Crit Care Med 2008;36:1735-1741.
    • (2008) Crit Care Med , vol.36 , pp. 1735-1741
    • Gacouin, A.1    Legay, F.2    Camus, C.3    Volatron, A.C.4    Barbarot, N.5    Donnio, P.Y.6    Thomas, R.7    Le Tulzo, Y.8
  • 38
    • 77049280844 scopus 로고
    • Zinc metabolism in hepatic dysfunction. I. Serum zinc concentrations in Laennec's cirrhosis and their validation by sequential analysis
    • Bartholomay AF, Robin ED, Vallee RL, Wacker WE. Zinc metabolism in hepatic dysfunction. I. Serum zinc concentrations in Laennec's cirrhosis and their validation by sequential analysis. N Engl J Med 1956;255:403-408.
    • (1956) N Engl J Med , vol.255 , pp. 403-408
    • Bartholomay, A.F.1    Robin, E.D.2    Vallee, R.L.3    Wacker, W.E.4
  • 39
    • 0025358944 scopus 로고
    • Relation between zinc status and hepatic functional reserve in patients with liver disease
    • Goode HF, Kelleher J, Walker BE. Relation between zinc status and hepatic functional reserve in patients with liver disease. Gut 1990;31:694-697.
    • (1990) Gut , vol.31 , pp. 694-697
    • Goode, H.F.1    Kelleher, J.2    Walker, B.E.3
  • 40
    • 70350070340 scopus 로고    scopus 로고
    • Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferatoractivated receptor-alpha
    • Kang X, Zhong W, Liu J, Song Z, McClain CJ, Kang YJ, Zhou Z. Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferatoractivated receptor-alpha. Hepatology 2009;50:1241-1250.
    • (2009) Hepatology , vol.50 , pp. 1241-1250
    • Kang, X.1    Zhong, W.2    Liu, J.3    Song, Z.4    McClain, C.J.5    Kang, Y.J.6    Zhou, Z.7
  • 41
    • 43249086787 scopus 로고    scopus 로고
    • Zinc supplementation inhibits hepatic apoptosis in mice subjected to a long-term ethanol exposure
    • Zhou Z, Liu J, Song Z, McClain CJ, Kang YJ. Zinc supplementation inhibits hepatic apoptosis in mice subjected to a long-term ethanol exposure. Exp Biol Med (Maywood) 2008;233:540-548.
    • (2008) Exp Biol Med (Maywood) , vol.233 , pp. 540-548
    • Zhou, Z.1    Liu, J.2    Song, Z.3    McClain, C.J.4    Kang, Y.J.5
  • 42
    • 0023555115 scopus 로고
    • Serum and tissue concentrations of zinc after oral supplementation in chronic alcoholics with or without cirrhosis
    • Zarski JP, Arnaud J, Labadie H, Beaugrand M, Favier A, Rachail M. Serum and tissue concentrations of zinc after oral supplementation in chronic alcoholics with or without cirrhosis. Gastroenterol Clin Biol 1987;11:856-860.
    • (1987) Gastroenterol Clin Biol , vol.11 , pp. 856-860
    • Zarski, J.P.1    Arnaud, J.2    Labadie, H.3    Beaugrand, M.4    Favier, A.5    Rachail, M.6
  • 44
    • 0038720319 scopus 로고    scopus 로고
    • Zinc deficiency induces oxidative DNA damage and increases p53 expression in human lung fibroblasts
    • Ho E, Courtemanche C, Ames BN. Zinc deficiency induces oxidative DNA damage and increases p53 expression in human lung fibroblasts. J Nutr 2003;133:2543-2548.
    • (2003) J Nutr , vol.133 , pp. 2543-2548
    • Ho, E.1    Courtemanche, C.2    Ames, B.N.3
  • 45
    • 0034024644 scopus 로고    scopus 로고
    • Zinc deficiency induces oxidative stress and ap-1 activation in 3t3 cells
    • Oteiza PI, Clegg MS, Zago MP, Keen CL. Zinc deficiency induces oxidative stress and ap-1 activation in 3t3 cells. Free Radic Biol Med 2000;28:1091-1099.
    • (2000) Free Radic Biol Med , vol.28 , pp. 1091-1099
    • Oteiza, P.I.1    Clegg, M.S.2    Zago, M.P.3    Keen, C.L.4
  • 49
    • 80455163152 scopus 로고    scopus 로고
    • The oxidative stress of zinc deficiency
    • Eide DJ. The oxidative stress of zinc deficiency. Metallomics 2011;3:1124-1129.
    • (2011) Metallomics , vol.3 , pp. 1124-1129
    • Eide, D.J.1
  • 50
    • 78650177805 scopus 로고    scopus 로고
    • Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress, p38 MAPK activation, and p53 activation in mice
    • Zhao Y, Tan Y, Dai J, Li B, Guo L, Cui J, Wang G, Shi X, Zhang X, Mellen N, et al. Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress, p38 MAPK activation, and p53 activation in mice. Toxicol Lett 2011;200:100-106.
    • (2011) Toxicol Lett , vol.200 , pp. 100-106
    • Zhao, Y.1    Tan, Y.2    Dai, J.3    Li, B.4    Guo, L.5    Cui, J.6    Wang, G.7    Shi, X.8    Zhang, X.9    Mellen, N.10


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