Phosphorylation of KasB Regulates Virulence and Acid-Fastness in Mycobacterium tuberculosis

PLoS Pathogens

Volumn 10, Issue 5, 2014, Pages

  Vilchèze, Catherine ^a   Molle, Virginie ^b   Carrère Kremer, Séverine ^b   Leiba, Jade ^b   Mourey, Lionel ^c,d   Shenai, Shubhada ^e   Baronian, Grégory ^b   Tufariello, Joann ^a   Hartman, Travis ^a   Veyron Churlet, Romain ^b,h   Trivelli, Xavier ^b,f   Tiwari, Sangeeta ^a   Weinrick, Brian ^a   Alland, David ^e   Guérardel, Yann ^b,f   Jacobs Jr , William R ^a   Kremer, Laurent ^b,g  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b CNRS   (France)

^c INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^d UNIVERSITÉ DE TOULOUSE   (France)

^e RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^f UNIV LILLE   (France)

^g INSERM   (France)

^h INSERM U1019   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE; BACTERIAL PROTEIN; KASB PROTEIN, MYCOBACTERIUM TUBERCULOSIS; MYCOLIC ACID; PROTEIN SERINE THREONINE KINASE;

ANIMAL; C57BL MOUSE; CELL WALL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; GENETICS; LIPID METABOLISM; METABOLISM; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MOUSE; MYCOBACTERIUM TUBERCULOSIS; PATHOGENICITY; PHOSPHORYLATION; PROCEDURES; SCID MOUSE; STAINING; TUBERCULOSIS; VIRULENCE;

3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE; ANIMALS; BACTERIAL PROTEINS; CATALYTIC DOMAIN; CELL WALL; LIPID METABOLISM; MICE; MICE, INBRED C57BL; MICE, SCID; MICROBIOLOGICAL TECHNIQUES; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; MYCOLIC ACIDS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; STAINING AND LABELING; TUBERCULOSIS; VIRULENCE;

EID: 84901648556     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004115     Document Type: Article

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