Immunomodulatory activity of commonly used drugs on Fc-receptor-mediated human natural killer cell activation

Cancer Immunology, Immunotherapy

Volumn 63, Issue 6, 2014, Pages 627-641

  Theorell, Jakob ^a   Gustavsson, Anna Lena ^b   Tesi, Bianca ^a   Sigmundsson, Kristmundur ^b   Ljunggren, Hans Gustaf ^a   Lundbäck, Thomas ^b   Bryceson, Yenan T ^a,c  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF BERGEN   (Norway)

Author keywords

CD107a; Cytotoxicity; Humans; Natural killer cells; Prestwick Chemical Library; Small molecule screening

Indexed keywords

ANTIBODY; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CD16 ANTIGEN; CD69 ANTIGEN; CHEMOKINE; CYCLOHEXIMIDE; CYCLOSPORIN A; DIHYDROPYRIDINE DERIVATIVE; DNA TOPOISOMERASE INHIBITOR; DOPAMINE RECEPTOR BLOCKING AGENT; ERGOSTEROL; FC RECEPTOR; GAMMA INTERFERON; HISTAMINE H1 RECEPTOR ANTAGONIST; IMMUNOMODULATING AGENT; LINCOMYCIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MEFLOQUINE; MORACIZINE; PHENYLETHANOLAMINE; PHOSPHODIESTERASE IV INHIBITOR; PODOPHYLLOTOXIN; PROSTAGLANDIN DERIVATIVE; SEROTONIN ANTAGONIST; SERTRALINE; TRACAZOLATE; TUMOR NECROSIS FACTOR; UNINDEXED DRUG;

ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CANCER IMMUNOTHERAPY; CELL ADHESION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG APPROVAL; DRUG EFFECT; DRUG SCREENING; EFFECTOR CELL; EXOCYTOSIS; FLOW CYTOMETRY; HIGH THROUGHPUT SCREENING; HUMAN; IMMUNOMODULATION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; MALIGNANT NEOPLASTIC DISEASE; NATURAL KILLER CELL; NORMAL HUMAN; PRIORITY JOURNAL; TREATMENT RESPONSE;

ANTIBODIES, MONOCLONAL; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; CYTOTOXICITY, IMMUNOLOGIC; FLOW CYTOMETRY; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; IMMUNITY, CELLULAR; IMMUNOLOGIC FACTORS; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; PHARMACEUTICAL PREPARATIONS; RECEPTORS, FC;

EID: 84901604086     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-014-1539-6     Document Type: Article

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