Engineering of a butyraldehyde dehydrogenase of Clostridium saccharoperbutylacetonicum to fit an engineered 1,4-butanediol pathway in Escherichia coli

Biotechnology and Bioengineering

Volumn 111, Issue 7, 2014, Pages 1374-1384

  Hwang, Hee Jin ^a   Park, Jin Hwan ^b   Kim, Jin Ho ^a   Kong, Min Kyung ^a   Kim, Jin Won ^a   Park, Jin Woo ^b   Cho, Kwang Myung ^b   Lee, Pyung Cheon ^a  

^a Ajou University   (South Korea)

^b Samsung Advanced Institute of Technology (SAIT)   (South Korea)

Author keywords

1,4 butanediol; Butyraldehyde dehydrogenase; Metabolic engineering

Indexed keywords

AMINO ACIDS; CLOSTRIDIUM; METABOLIC ENGINEERING;

1 ,4-BUTANEDIOL; BUTYRALDEHYDE DEHYDROGENASE; CLOSTRIDIUM SACCHAROPERBUTYLACETONICUM; ENGINEERED ESCHERICHIA COLI; ENZYMATIC REACTION; RANDOM MUTAGENESIS; SITE DIRECTED MUTAGENESIS; WILD TYPES;

ESCHERICHIA COLI;

1,4 BUTANEDIOL; BACTERIAL ENZYME; BUTANOL DEHYDROGENASE; BUTYRALDEHYDE DEHYDROGENASE; MUTANT PROTEIN; OXIDOREDUCTASE; UNCLASSIFIED DRUG; 1,4-BUTANEDIOL; ALDEHYDE DEHYDROGENASE; BUTANEDIOL; BUTYRALDEHYDE DEHYDROGENASE (COENZYME A-LINKED);

ARTICLE; CLOSTRIDIUM; CLOSTRIDIUM SACCHAROPERBUTYLACETONICUM; COLORIMETRY; CONTROLLED STUDY; ENZYME ENGINEERING; ESCHERICHIA COLI; NONHUMAN; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS; ENZYMOLOGY; GENETICS; METABOLIC ENGINEERING; METABOLISM; MUTAGENESIS; PROCEDURES;

CLOSTRIDIUM SACCHAROPERBUTYLACETONICUM; ESCHERICHIA COLI;

ALDEHYDE OXIDOREDUCTASES; BUTYLENE GLYCOLS; CLOSTRIDIUM; ESCHERICHIA COLI; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; MUTAGENESIS; MUTANT PROTEINS;

EID: 84901586092     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25196     Document Type: Article

References (32)

1. Ahmed M, Goldgur Y, Hu J, Guo H, Cheung NV. 2013. In silico driven redesign of a clinically relevant antibody for the treatment of GD2 positive tumors. PLoS ONE 8:e63359.
2. Charneira C, Godinho AL, Oliveira MC, Pereira SA, Monteiro EC, Marques MM, Antunes AM. 2011. Reactive aldehyde metabolites from the anti-HIV drug abacavir: Amino acid adducts as possible factors in abacavir toxicity. Chem Res Toxicol 24:2129-2141.
3. D'Ambrosio K, Pailot A, Talfournier F, Didierjean C, Benedetti E, Aubry A, Branlant G, Corbier C. 2006. The first crystal structure of a thioacylenzyme intermediate in the ALDH family: New coenzyme conformation and relevance to catalysis. Biochem 45:2978-2986.
4. Datsenko KA, Wanner BL. 2000. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A 97:6640-6645.
5. Di Costanzo L, Gomez GA, Christianson DW. 2007. Crystal structure of lactaldehyde dehydrogenase from Escherichia coli and inferences regarding substrate and cofactor specificity. J Mol Biol 366:481-493.
6. Eswar N, Eramian D, Webb B, Shen MY, Sali A. 2008. Protein structure modeling with MODELLER. Methods Mol Biol 426:145-159.
7. Gibson LT, Kerr WJ, Nordon A, Reglinski J, Robertson C, Turnbull L, Watt CM, Cheung A, Johnstone W. 2008. On-site determination of formaldehyde: A low cost measurement device for museum environments. Anal Chim Acta 623:109-116.
8. Hart C, Schulenberg B, Steinberg TH, Leung WY, Patton WF. 2003. Detection of glycoproteins in polyacrylamide gels and on electroblots using Pro-Q Emerald 488 dye, a fluorescent periodate Schiff-base stain. Electrophoresis 24:588-598.
9. Hasehira K, Miyanishi N, Sumiyoshi W, Hirabayashi J, Nakakita S. 2011. Development of a chemical strategy to produce rare aldohexoses from ketohexoses using 2-aminopyridine. Carbohydr Res 346:2693-2698.
10. Heo J, Kim SH, Lee PC. 2013. New insight into the cleavage reaction of Nostoc sp. PCC7120 carotenoid cleavage dioxygenase in natural and non-natural carotenoids. Appl Environ Microbiol
11. Imai S, Ichikawa K, Muramatsu Y, Kasai D, Masai E, Fukuda M. 2011. Isolation and characterization of Streptomyces, Actinoplanes, and Methylibium strains that are involved in degradation of natural rubber and synthetic poly(cis-1, 4-isoprene). Enzyme Microb Technol 49:526-531.
12. Kim SH, Park YH, Schmidt-Dannert C, Lee PC. 2010. Redesign, reconstruction, and directed extension of the Brevibacterium linens C40 carotenoid pathway in Escherichia coli. Appl Environ Microbiol 76:5199-5206.
13. Kovach ME, Elzer PH, Hill DS, Robertson GT, Farris MA, Roop RM II, Peterson KM. 1995. Four new derivatives of the broad-host-range cloning vector pBBR1MCS, carrying different antibiotic-resistance cassettes. Gene 166:175-176.
14. Lee PC, Mijts BN, Petri R, Watts KT, Schmidt-Dannert C. 2004. Alteration of product specificity of Aeropyrum pernix farnesylgeranyl diphosphate synthase (Fgs) by directed evolution. Protein Eng Des Sel 17:771-777.
15. Lee PC, Petri R, Mijts BN, Watts KT, Schmidt-Dannert C. 2005. Directed evolution of Escherichia coli farnesyl diphosphate synthase (IspA) reveals novel structural determinants of chain length specificity. Metab Eng 7:18-26.
16. Lee KH, Park JH, Kim TY, Kim HU, Lee SY. 2007. Systems metabolic engineering of Escherichia coli for L-threonine production. Mol Syst Biol 3:149.
17. Lee PC, Lee SY, Chang HN. 2008. Succinic acid production by Anaerobiospirillum succiniciproducens ATCC 29305 growing on galactose, galactose/glucose, and galactose/lactose. J Microbiol Biotechnol 18:1792-1796.
18. Liu ZJ, Sun YJ, Rose J, Chung YJ, Hsiao CD, Chang WR, Kuo I, Perozich J, Lindahl R, Hempel J, Wang BC. 1997. The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold. Nat Struct Biol 4:317-326.
19. Nielsen DR, Leonard E, Yoon SH, Tseng HC, Yuan C, Prather KL. 2009. Engineering alternative butanol production platforms in heterologous bacteria. Metab Eng 11:262-273.
20. Palmeros B, Wild J, Szybalski W, Le Borgne S, Hernandez-Chavez G, Gosset G, Valle F, Bolivar F. 2000. A family of removable cassettes designed to obtain antibiotic-resistance-free genomic modifications of Escherichia coli and other bacteria. Gene 247:255-264.
21. Park JH, Lee KH, Kim TY, Lee SY. 2007. Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation. Proc Natl Acad Sci U S A 104:7797-7802.
22. Qi X, Chen Y, Jiang K, Zuo W, Luo Z, Wei Y, Du L, Wei H, Huang R, Du Q. 2009. Saturation-mutagenesis in two positions distant from active site of a Klebsiella pneumoniae glycerol dehydratase identifies some highly active mutants. J Biotechnol 144:43-50.
23. Schmidt-Dannert C, Lee P, Mijts B. 2006. Creating carotenoid diversity in E. coli cells using combinatorial and directed evolution strategies. Phytochem Rev 5:67-74.
24. Schweizer HP. 1992. Allelic exchange in Pseudomonas aeruginosa using novel ColE1-type vectors and a family of cassettes containing a portable oriT and the counter-selectable Bacillus subtilis SacB marker. Mol Microbiol 6:1195-1204.
25. Shuster A, Osherov N, Rosenberg M. 2004. Alcohol-mediated haemolysis in yeast. Yeast 21:1335-1342.
26. Spassov VZ, Yan L. 2013. pH-Selective mutagenesis of protein-protein interface: In silico design of therapeutic antibodies with prolonged half-life. Proteins 81:704-714.
27. Sun W, Wang S, Curtiss R III. 2008. Highly efficient method for introducing successive multiple scarless gene deletion and markerless gene insertions into the Yersinia pestis chromosome. Appl Environ Microbiol 74:4241-4245.
28. Yan RT, Chen JS. 1990. Coenzyme A-acylating aldehyde dehydrogenase from Clostridium beijerinckii NRRL B592. Appl Environ Microbiol 56:2591-2599.
29. Yang R, Li K, Liu F, Li N, Zhao F, Chan W. 2003. 3, 3′, 5, 5′-tetramethyl-N-(9-anthrylmethyl)benzidine: A dual-signaling fluorescent reagent for optical sensing of aliphatic aldehydes. Anal Chem 75:3908-3914.
30. Yim H, Haselbeck R, Niu W, Pujol-Baxley C, Burgard A, Boldt J, Khandurina J, Trawick JD, Osterhout RE, Stephen R, Estadilla J, Teisan S, Schreyer HB, Andrae S, Yang TH, Lee SY, Burk MJ, Van Dien S. 2011. Metabolic engineering of Escherichia coli for direct production of 1, 4-butanediol. Nat Chem Biol 7:445-452.
31. Yu M, Zhang Y, Tang IC, Yang ST. 2011. Metabolic engineering of Clostridium tyrobutyricum for n-butanol production. Metab Eng 13:373-382.
32. Zeng AP, Sabra W. 2011. Microbial production of diols as platform chemicals: Recent progresses. Curr Opin Biotechnol 22:749-757.