Effect of a Tart Cherry Juice Supplement on Arterial Stiffness and Inflammation in Healthy Adults: A Randomised Controlled Trial

Plant Foods for Human Nutrition

Volumn 69, Issue 2, 2014, Pages 122-127

  Lynn, Anthony ^a   Mathew, Shilpa ^b   Moore, Chris T ^b   Russell, Jean ^b   Robinson, Emma ^b   Soumpasi, Vithleem ^b   Barker, Margo E ^b  

^a SHEFFIELD HALLAM UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Arterial stiffness; Blood pressure; Cherry; Inflammation

Indexed keywords

ANTIOXIDANT; C REACTIVE PROTEIN; CHOLESTEROL;

ADULT; ARTERIAL STIFFNESS; BEVERAGE; BLOOD; BLOOD PRESSURE; CHEMISTRY; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIET THERAPY; DRUG EFFECTS; FEMALE; HUMAN; INFLAMMATION; MALE; MIDDLE AGED; PRUNUS; RANDOMIZED CONTROLLED TRIAL;

ADULT; ANTIOXIDANTS; BEVERAGES; BLOOD PRESSURE; C-REACTIVE PROTEIN; CHOLESTEROL; DIETARY SUPPLEMENTS; FEMALE; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; PRUNUS; VASCULAR STIFFNESS;

EID: 84901402261     PISSN: 09219668     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11130-014-0409-x     Document Type: Article

References (34)

1. Huxley RR, Neil HA (2003) The relation between dietary flavonol intake and coronary heart disease mortality: a meta-analysis of prospective cohort studies. Eur J Clin Nutr 57: 904-908.
2. Mink PJ, Scrafford CG, Barraj LM et al (2007) Flavonoid intake and cardiovascular disease mortality: a prospective study in post-menopausal women. Am J Clin Nutr 85: 895-909.
3. Cassidy A, Mukamal KJ, Lui L et al (2013) High anthocyanin intake is associated with a reduced risk of myocardial infarction in young and middle-aged women. Circulation 127: 188-196.
4. Kirakosyan A, Seymour EM, Llanes DE et al (2009) Chemical profile and antioxidant capacities of tart cherry products. Food Chem 115: 20-25.
5. Yao LH, Jiang YM, Shi J et al (2004) Flavonoids in food and their health benefits. Plant Foods Hum Nutr 59: 113-122.
6. Wang H, Nair MG, Strasburg GM et al (1999) Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries. J Nat Prod 62: 294-296.
7. Seeram NP, Momin RA, Nair MG, Bourquin LD (2001) Cyclooxygenase inhibitory and antioxidant cyanidin glycosides in cherries and berries. Phytomedicine 8: 362-369.
8. Xu JW, Ikeda K, Yamon Y (2004) Upregulation of endothelial nitric oxide synthase by cyanidin-3-glucoside, a typical anthocyanin pigment. Hypertension 44: 217-222.
9. Saric A, Saobacanec S, Balog T et al (2009) Improved antioxidant and anti-inflammatory potential in mice consuming sour cherry juice (Prunus cerasus cv. Maraska). Plant Foods Hum Nutr 64: 231-237.
10. Kelley DS, Rasooly R, Jacob RA et al (2006) Consumption of Bing sweet cherries lowers circulating concentrations of inflammation markers in healthy men and women. J Nutr 136: 981-986.
11. Kelley DS, Adkins Y, Reddy A et al (2013) Sweet Bing cherries lower circulating concentrations of markers for chronic inflammatory diseases in healthy humans. J Nutr 143: 340-344.
12. Connolly DA, McHugh MP, Padilla-Zakour OI et al (2006) Efficacy of a tart cherry juice blend in preventing symptoms of muscle damage. Br J Sports Med 40: 679-683.
13. Howatson G, McHugh MP, Hill JA et al (2010) Influence of tart cherry juice on indices of recovery following marathon running. Scand J Med Sci Sports 20: 843-852.
14. Jennings A, Welch AA, Fairweather-Tait SJ et al (2012) Higher anthocyanin intake is associated with lower arterial stiffness and central blood pressure in women. Am J Clin Nutr 96: 781-788.
15. McEniery CM, Wallace S, Mackenzie IS et al (2006) Endothelial function is associated with pulse pressure, pulse wave velocity, and augmentation index in healthy humans. Hypertension 48: 602-608.
16. Bell DR, Gochenaur K (2006) Direct vasoactive and vasoprotective properties of anthocyanin-rich extracts. J Appl Physiol 110: 1164-1170. doi: 10. 1152/japplphysiol. 00626. 2005.
17. Zhu Y, Xia M, Yang Y et al (2011) Purified anthocyanin supplementation improves endothelial function via NO-cGMP activation in hypercholesterolemic individuals. Clin Chem 57: 1524-1533.
18. Dohadwala MM, Holbrook M, Hamburg NM et al (2011) Effects of cranberry juice consumption on vascular function in patients with coronary artery disease. Am J Clin Nutr 93: 934-940.
19. Bonerz D, Würth K, Dietrich H, Will F (2007) Anthocyanin characterisation and impact of ageing on anthocyanin composition and degradation in juices from five sour cherry cultivars. Eur Food Res Technol 224: 355-364.
20. Howatson G, Bell PG, Tallent J et al (2012) Effect of tart cherry juice (Prunus cerasus) on melatonin levels and enhanced sleep quality. Eur J Nutr 51: 909-916.
21. Lynn A, Hamadeh H, Leung WC et al (2012) Effects of pomegranate juice supplementation on pulse wave velocity and blood pressure in healthy young and middle-aged men and women. Plant Foods Hum Nutr 67: 309-314.
22. Naismith DJ, Braschi A (2003) The effect of low-dose potassium supplementation on blood pressure in apparently healthy volunteers. Br J Nutr 90: 53-56.
23. O'Brien E, Waeber B, Parati G et al (2001) Blood pressure measuring devices: recommendations of the European Society of Hypertension. BMJ 322: 531-536.
24. Benzie IF, Strain JJ (1999) Ferric reducing/antioxidant power assay: direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration. Methods Enzymol 299: 15-27.
25. Vickers AJ, Altman DJ (2001) Analysing controlled trials with baseline and follow up measurements. BMJ 323: 1123-1124.
26. Bland M (2000) An introduction to medical statistics, 3rd edn. Oxford University Press, Oxford.
27. Ryu OH, Lee J, Lee KW et al (2006) Effects of green tea consumption on inflammation, insulin resistance and pulse wave velocity in type 2 diabetes patients. Diabetes Res Clin Pract 71: 356-358.
28. Teede HJ, McGrath BP, DeSilva L et al (2003) Isoflavones reduce arterial stiffness: a placebo-controlled study in men and postmenopausal women. Arterioscler Thromb Vasc Biol 23: 1066-1071.
29. Hasselhund SS, Flaa A, Sandvik L et al (2012) Effects of anthocyanins on blood pressure and stress reactivity: a double-blind randomized placebo-controlled crossover study. J Hum Hypertens 26: 396-404.
30. Curtis PJ, Kroon PA, Hollands WJ et al (2009) Cardiovascular disease risk biomarkers and liver and kidney function are not altered in postmenopausal women after ingesting an elderberry extract rich in anthocyanins for 12 weeks. J Nutr 139: 2266-2271.
31. Chong MFF, MacDonald R, Lovegrove JA (2010) Fruit polyphenols and CVD risk: a review of human intervention studies. Br J Nutr 104: S28-S39.
32. Ridker PM, Hennekens CH, Buring JE, Rifai N (2000) C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 342: 836-842.
33. Damar I, Eksi A (2012) Antioxidant capacity and anthocyanin profile of sour cherry (Prunus cerasus L.) juice. Food Chem 135: 2910-2914.
34. Jacob RA, Spinozzi GM, Simon VA et al (2003) Consumption of cherries lowers plasma urate in healthy women. J Nutr 133: 1826-1829.