SiRNA-phospholipid conjugates for gene and drug delivery in cancer treatment

Biomaterials

Volumn 35, Issue 24, 2014, Pages 6519-6533

  Liu, Hongmei ^a,b   Li, Yan ^a,b   Mozhi, Anbu ^c   Zhang, Liang ^a,b   Liu, Yilan ^a,b   Xu, Xia ^a   Xing, Jianmin ^a   Liang, Xingjie ^c   Ma, Guanghui ^a   Yang, Jun ^a   Zhang, Xin ^a  

^a INSTITUTE OF PROCESS ENGINEERING   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY   (China)

Author keywords

Combined effect; Gene silencing; Loading efficiency; SiRNA phospholipids conjugate

Indexed keywords

DRUG DELIVERY; GENE EXPRESSION; HYDROPHOBICITY; NANOPARTICLES; RNA; TUMORS;

ANTI-CANCER DRUG DELIVERY; BINDING ABILITIES; CLINICAL APPLICATION; COMBINED EFFECT; GENE SILENCING; LOADING EFFICIENCY; SIRNA-PHOSPHOLIPIDS CONJUGATE; SMALL INTERFERING RNA (SIRNA);

PHOSPHOLIPIDS;

CELL CYCLE PROTEIN; DOXORUBICIN; NANOPARTICLE; ONCOPROTEIN; PHOSPHOLIPID; POLO-LIKE KINASE 1; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA;

ANIMAL; APOPTOSIS; BAGG ALBINO MOUSE; CELL PROLIFERATION; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; ENDOCYTOSIS; FEMALE; GENE SILENCING; GENE TRANSFER; HELA CELL LINE; HUMAN; METABOLISM; NEOPLASMS; NICK END LABELING; NUDE MOUSE; SYNTHESIS; ULTRASTRUCTURE;

ANIMALS; APOPTOSIS; CELL CYCLE PROTEINS; CELL PROLIFERATION; DOXORUBICIN; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; FEMALE; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; GENE TRANSFER TECHNIQUES; HELA CELLS; HUMANS; IN SITU NICK-END LABELING; MICE, INBRED BALB C; MICE, NUDE; NANOPARTICLES; NEOPLASMS; PHOSPHOLIPIDS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RNA, SMALL INTERFERING;

EID: 84901390115     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.04.033     Document Type: Article

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