메뉴 건너뛰기




Volumn 22, Issue 9, 2011, Pages 1737-1752

Nucleic acid carriers based on precise polymer conjugates

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; FUNCTIONAL POLYMERS; NUCLEIC ACIDS; POLYDISPERSITY; SYNTHESIS (CHEMICAL);

EID: 80053073179     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc200251r     Document Type: Review
Times cited : (66)

References (145)
  • 1
    • 67249096677 scopus 로고    scopus 로고
    • Nonviral methods for siRNA delivery
    • Gao, K. and Huang, L. (2008) Nonviral methods for siRNA delivery Mol. Pharmaceutics 6, 651-658
    • (2008) Mol. Pharmaceutics , vol.6 , pp. 651-658
    • Gao, K.1    Huang, L.2
  • 3
    • 48949098577 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Synthetic polymer-based systems
    • Schaffert, D. and Wagner, E. (2008) Gene therapy progress and prospects: synthetic polymer-based systems Gene Ther. 15, 1131-1138
    • (2008) Gene Ther. , vol.15 , pp. 1131-1138
    • Schaffert, D.1    Wagner, E.2
  • 4
    • 37549032712 scopus 로고    scopus 로고
    • Breaking the bonds: Non-viral vectors become chemically dynamic
    • Wolff, J. A. and Rozema, D. B. (2008) Breaking the bonds: non-viral vectors become chemically dynamic Mol. Ther. 16, 8-15
    • (2008) Mol. Ther. , vol.16 , pp. 8-15
    • Wolff, J.A.1    Rozema, D.B.2
  • 5
    • 1642579669 scopus 로고    scopus 로고
    • Strategies to Improve DNA Polyplexes for in Vivo Gene Transfer: Will "Artificial Viruses" Be the Answer?
    • DOI 10.1023/B:PHAM.0000012146.04068.56
    • Wagner, E. (2004) Strategies to improve DNA polyplexes for in vivo gene transfer: will "artificial viruses" be the answer? Pharm. Res. 21, 8-14 (Pubitemid 38122286)
    • (2004) Pharmaceutical Research , vol.21 , Issue.1 , pp. 8-14
    • Wagner, E.1
  • 6
    • 37549072604 scopus 로고    scopus 로고
    • Converging paths of viral and non-viral vector engineering
    • Wagner, E. (2008) Converging paths of viral and non-viral vector engineering Mol. Ther. 16, 1-2
    • (2008) Mol. Ther. , vol.16 , pp. 1-2
    • Wagner, E.1
  • 7
    • 0026655684 scopus 로고
    • Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: Toward a synthetic virus-like gene-transfer vehicle
    • Wagner, E., Plank, C., Zatloukal, K., Cotten, M., and Birnstiel, M. L. (1992) Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle Proc. Natl. Acad. Sci. U.S.A. 89, 7934-7938
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 7934-7938
    • Wagner, E.1    Plank, C.2    Zatloukal, K.3    Cotten, M.4    Birnstiel, M.L.5
  • 9
    • 79952154606 scopus 로고    scopus 로고
    • Localized, targeted, and sustained siRNA delivery
    • Krebs, M. D. and Alsberg, E. (2011) Localized, targeted, and sustained siRNA delivery Chemistry 17, 3054-3062
    • (2011) Chemistry , vol.17 , pp. 3054-3062
    • Krebs, M.D.1    Alsberg, E.2
  • 10
    • 64549134676 scopus 로고    scopus 로고
    • Nonviral vectors for gene delivery
    • Mintzer, M. A. and Simanek, E. E. (2009) Nonviral vectors for gene delivery Chem. Rev. 109, 259-302
    • (2009) Chem. Rev. , vol.109 , pp. 259-302
    • Mintzer, M.A.1    Simanek, E.E.2
  • 12
    • 41149086686 scopus 로고    scopus 로고
    • Extracellular barriers to in vivo PEI and PEGylated PEI polyplex-mediated gene delivery to the liver
    • DOI 10.1021/bc700388u
    • Burke, R. S. and Pun, S. H. (2008) Extracellular barriers to in vivo PEI and PEGylated PEI polyplex-mediated gene delivery to the liver Bioconjugate Chem. 19, 693-704 (Pubitemid 351431402)
    • (2008) Bioconjugate Chemistry , vol.19 , Issue.3 , pp. 693-704
    • Burke, R.S.1    Pun, S.H.2
  • 13
    • 38649099106 scopus 로고    scopus 로고
    • Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum Dot-FRET
    • DOI 10.1038/sj.mt.6300392, PII 6300392
    • Chen, H. H., Ho, Y.-P., Jiang, X., Mao, H.-Q., Wang, T.-H., and Leong, K. W. (2008) Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum Dot-FRET Mol. Ther. 16, 324-332 (Pubitemid 351168042)
    • (2008) Molecular Therapy , vol.16 , Issue.2 , pp. 324-332
    • Chen, H.H.1    Ho, Y.-P.2    Jiang, X.3    Mao, H.-Q.4    Wang, T.-H.5    Leong, K.W.6
  • 14
    • 59249105606 scopus 로고    scopus 로고
    • Polymer-based gene delivery: A current review on the uptake and intracellular trafficking of polyplexes
    • Midoux, P., Breuzard, G., Gomez, J. P., and Pichon, C. (2008) Polymer-based gene delivery: a current review on the uptake and intracellular trafficking of polyplexes Curr. Gene Ther. 8, 335-352
    • (2008) Curr. Gene Ther. , vol.8 , pp. 335-352
    • Midoux, P.1    Breuzard, G.2    Gomez, J.P.3    Pichon, C.4
  • 15
    • 33747034448 scopus 로고    scopus 로고
    • Photochemical enhancement of transgene expression by polymeric micelles incorporating plasmid DNA and dendrimer-based photosensitizer
    • DOI 10.1080/10611860600834508, PII PMN3432N4XG6525H
    • Nishiyama, N., Arnida, Jang, W.-D., Date, K., Miyata, K., and Kataoka, K. (2006) Photochemical enhancement of transgene expression by polymeric micelles incorporating plasmid DNA and dendrimer-based photosensitizer J. Drug Targeting 14, 413-424 (Pubitemid 44207826)
    • (2006) Journal of Drug Targeting , vol.14 , Issue.6 , pp. 413-424
    • Nishiyama, N.1    Arnida2    Jang, W.-D.3    Date, K.4    Miyata, K.5    Kataoka, K.6
  • 16
    • 33746238256 scopus 로고    scopus 로고
    • Which mechanism for nuclear import of plasmid DNA complexed with polyethylenimine derivatives?
    • DOI 10.1002/jgm.915
    • Grosse, S., Thévenot, G., Monsigny, M., and Fajac, I. (2006) Which mechanism for nuclear import of plasmid DNA complexed with polyethylenimine derivatives? J. Gene Med. 8, 845-851 (Pubitemid 44097140)
    • (2006) Journal of Gene Medicine , vol.8 , Issue.7 , pp. 845-851
    • Grosse, S.1    Thevenot, G.2    Monsigny, M.3    Fajac, I.4
  • 18
    • 74949121350 scopus 로고    scopus 로고
    • Minireview: Delivering the code: Polyplex carriers for deoxyribonucleic acid and ribonucleic acid interference therapies
    • Christie, R. J., Nishiyama, N., and Kataoka, K. (2010) Minireview: Delivering the code: polyplex carriers for deoxyribonucleic acid and ribonucleic acid interference therapies Endocrinology 151, 466-473
    • (2010) Endocrinology , vol.151 , pp. 466-473
    • Christie, R.J.1    Nishiyama, N.2    Kataoka, K.3
  • 19
    • 0037437033 scopus 로고    scopus 로고
    • Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: Comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine
    • DOI 10.1016/S0168-3659(03)00076-2
    • Kunath, K., von Harpe, A., Fischer, D., Petersen, H., Bickel, U., Voigt, K., and Kissel, T. (2003) Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine J. Controled Release 89, 113-125 (Pubitemid 36412116)
    • (2003) Journal of Controlled Release , vol.89 , Issue.1 , pp. 113-125
    • Kunath, K.1    Von Harpe, A.2    Fischer, D.3    Petersen, H.4    Bickel, U.5    Voigt, K.6    Kissel, T.7
  • 20
    • 3242707528 scopus 로고    scopus 로고
    • In situ single cell observation by fluorescence resonance energy transfer reveals fast intra-cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine
    • DOI 10.1002/jgm.470
    • Itaka, K., Harada, A., Yamasaki, Y., Nakamura, K., Kawaguchi, H., and Kataoka, K. (2004) In situ single cell observation by fluorescence resonance energy transfer reveals fast intra-cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine J. Gene Med. 6, 76-84 (Pubitemid 40228005)
    • (2004) Journal of Gene Medicine , vol.6 , Issue.1 , pp. 76-84
    • Itaka, K.1    Harada, A.2    Yamasaki, Y.3    Nakamura, K.4    Kawaguchi, H.5    Kataoka, K.6
  • 21
    • 0035286969 scopus 로고    scopus 로고
    • Polyethylenimine-mediated gene delivery: A mechanistic study
    • DOI 10.1002/jgm.173
    • Kichler, A., Leborgne, C., Coeytaux, E., and Danos, O. (2001) Polyethylenimine-mediated gene delivery: a mechanistic study J. Gene Med. 3, 135-144 (Pubitemid 33685440)
    • (2001) Journal of Gene Medicine , vol.3 , Issue.2 , pp. 135-144
    • Kichler, A.1    Leborgne, C.2    Coeytaux, E.3    Danos, O.4
  • 22
    • 0242414440 scopus 로고    scopus 로고
    • Chloride Accumulation and Swelling in Endosomes Enhances DNA Transfer by Polyamine-DNA Polyplexes
    • DOI 10.1074/jbc.M308643200
    • Sonawane, N. D., Szoka, F. C., Jr., and Verkman, A. S. (2003) Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes J. Biol. Chem. 278, 44826-44831 (Pubitemid 37377241)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.45 , pp. 44826-44831
    • Sonawane, N.D.1    Szoka Jr., F.C.2    Verkman, A.S.3
  • 23
    • 19744372388 scopus 로고    scopus 로고
    • Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis
    • DOI 10.1002/jgm.696
    • Akinc, A., Thomas, M., Klibanov, A. M., and Langer, R. (2005) Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis J. Gene Med. 7, 657-663 (Pubitemid 40744532)
    • (2005) Journal of Gene Medicine , vol.7 , Issue.5 , pp. 657-663
    • Akinc, A.1    Thomas, M.2    Klibanov, A.M.3    Langer, R.4
  • 24
    • 0034152683 scopus 로고    scopus 로고
    • Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse
    • Zou, S. M., Erbacher, P., Remy, J. S., and Behr, J. P. (2000) Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse J. Gene Med. 2, 128-134
    • (2000) J. Gene Med. , vol.2 , pp. 128-134
    • Zou, S.M.1    Erbacher, P.2    Remy, J.S.3    Behr, J.P.4
  • 25
    • 0035408714 scopus 로고    scopus 로고
    • Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo
    • DOI 10.1002/jgm.187
    • Wightman, L., Kircheis, R., Rossler, V., Carotta, S., Ruzicka, R., Kursa, M., and Wagner, E. (2001) Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo J. Gene Med. 3, 362-372 (Pubitemid 33691776)
    • (2001) Journal of Gene Medicine , vol.3 , Issue.4 , pp. 362-372
    • Wightman, L.1    Kircheis, R.2    Rossler, V.3    Garotta, S.4    Ruzicka, R.5    Kursa, M.6    Wagner, E.7
  • 26
    • 33847120795 scopus 로고    scopus 로고
    • Biodistribution and tissue expression kinetics of plasmid DNA complexed with polyethylenimines of different molecular weight and structure
    • (2007). 118, 118 - 125.
    • Jeong, G. J., Byun, H. M., Kim, J. M., Yoon, H., Choi, H. G., Kim, W. K., Kim, S. J., and Oh, Y. K. (2007) Biodistribution and tissue expression kinetics of plasmid DNA complexed with polyethylenimines of different molecular weight and structure. J. Controlled Release 118, 118 - 125.
    • J. Controlled Release
    • Jeong, G.J.1    Byun, H.M.2    Kim, J.M.3    Yoon, H.4    Choi, H.G.5    Kim, W.K.6    Kim, S.J.7    Oh, Y.K.8
  • 27
    • 33646152761 scopus 로고    scopus 로고
    • A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes
    • Werth, S., Urban-Klein, B., Dai, L., Hobel, S., Grzelinski, M., Bakowsky, U., Czubayko, F., and Aigner, A. (2006) A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes J. Controlled Release 112, 257-270
    • (2006) J. Controlled Release , vol.112 , pp. 257-270
    • Werth, S.1    Urban-Klein, B.2    Dai, L.3    Hobel, S.4    Grzelinski, M.5    Bakowsky, U.6    Czubayko, F.7    Aigner, A.8
  • 28
    • 37249070918 scopus 로고    scopus 로고
    • Novel degradable oligoethylenimine acrylate ester-based pseudodendrimers for in vitro and in vivo gene transfer
    • DOI 10.1038/sj.gt.3303046, PII 3303046
    • Russ, V., Elfberg, H., Thoma, C., Kloeckner, J., Ogris, M., and Wagner, E. (2008) Novel degradable oligoethylenimine acrylate ester-based pseudodendrimers for in vitro and in vivo gene transfer Gene Ther. 15, 18-29 (Pubitemid 350269429)
    • (2008) Gene Therapy , vol.15 , Issue.1 , pp. 18-29
    • Russ, V.1    Elfberg, H.2    Thoma, C.3    Kloeckner, J.4    Ogris, M.5    Wagner, E.6
  • 29
    • 32044465218 scopus 로고    scopus 로고
    • EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice
    • Shir, A., Ogris, M., Wagner, E., and Levitzki, A. (2006) EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice PLoS Med. 3, e6
    • (2006) PLoS Med. , vol.3 , pp. 6
    • Shir, A.1    Ogris, M.2    Wagner, E.3    Levitzki, A.4
  • 30
    • 78651412590 scopus 로고    scopus 로고
    • Precise synthesis of molecularly defined oligomers and polymers by orthogonal iterative divergent/convergent approaches
    • Binauld, S., Damiron, D., Connal, L. A., Hawker, C. J., and Drockenmuller, E. (2011) Precise synthesis of molecularly defined oligomers and polymers by orthogonal iterative divergent/convergent approaches Macromol. Rapid Commun. 32, 147-168
    • (2011) Macromol. Rapid Commun. , vol.32 , pp. 147-168
    • Binauld, S.1    Damiron, D.2    Connal, L.A.3    Hawker, C.J.4    Drockenmuller, E.5
  • 31
    • 77950796120 scopus 로고    scopus 로고
    • Sequence-controlled polymerizations: The next Holy Grail in polymer science?
    • Lutz, J.-F. (2010) Sequence-controlled polymerizations: the next Holy Grail in polymer science? Polym. Chem. 1, 55-62
    • (2010) Polym. Chem. , vol.1 , pp. 55-62
    • Lutz, J.-F.1
  • 32
    • 67949112461 scopus 로고    scopus 로고
    • Nanostructured functional materials prepared by atom transfer radical polymerization
    • Matyjaszewski, K. and Tsarevsky, N. V. (2009) Nanostructured functional materials prepared by atom transfer radical polymerization Nat. Chem. 1, 276-288
    • (2009) Nat. Chem. , vol.1 , pp. 276-288
    • Matyjaszewski, K.1    Tsarevsky, N.V.2
  • 33
    • 73249130329 scopus 로고    scopus 로고
    • A renaissance in living cationic polymerization
    • Aoshima, S. and Kanaoka, S. (2009) A renaissance in living cationic polymerization Chem. Rev. 109, 5245-5287
    • (2009) Chem. Rev. , vol.109 , pp. 5245-5287
    • Aoshima, S.1    Kanaoka, S.2
  • 34
    • 36249022651 scopus 로고    scopus 로고
    • Poly(2-oxazolines) in biological and biomedical application contexts
    • DOI 10.1016/j.addr.2007.08.018, PII S0169409X07001901
    • Adams, N. and Schubert, U. S. (2007) Poly(2-oxazolines) in biological and biomedical application contexts Adv. Drug Delivery Rev. 59, 1504-1520 (Pubitemid 350122776)
    • (2007) Advanced Drug Delivery Reviews , vol.59 , Issue.15 , pp. 1504-1520
    • Adams, N.1    Schubert, U.S.2
  • 35
    • 57149137351 scopus 로고    scopus 로고
    • Systemic delivery of DNA or siRNA mediated by linear polyethylenimine (L-PEI) does not induce an inflammatory response
    • Bonnet, M. E., Erbacher, P., and Bolcato-Bellemin, A. L. (2008) Systemic delivery of DNA or siRNA mediated by linear polyethylenimine (L-PEI) does not induce an inflammatory response Pharm. Res. 25, 2972-2982
    • (2008) Pharm. Res. , vol.25 , pp. 2972-2982
    • Bonnet, M.E.1    Erbacher, P.2    Bolcato-Bellemin, A.L.3
  • 36
    • 55549102623 scopus 로고    scopus 로고
    • Phase I/II marker lesion study of intravesical BC-819 DNA plasmid in H19 over expressing superficial bladder cancer refractory to bacillus Calmette-Guerin
    • Sidi, A. A., Ohana, P., Benjamin, S., Shalev, M., Ransom, J. H., Lamm, D., Hochberg, A., and Leibovitch, I. (2008) Phase I/II marker lesion study of intravesical BC-819 DNA plasmid in H19 over expressing superficial bladder cancer refractory to bacillus Calmette-Guerin J. Urol. 180, 2379-2383
    • (2008) J. Urol. , vol.180 , pp. 2379-2383
    • Sidi, A.A.1    Ohana, P.2    Benjamin, S.3    Shalev, M.4    Ransom, J.H.5    Lamm, D.6    Hochberg, A.7    Leibovitch, I.8
  • 40
    • 20744456789 scopus 로고
    • Solid phase peptide synthesis. I. The synthesis of a tetrapeptide
    • Merrifield, R. B. (1963) Solid phase peptide synthesis. I. The synthesis of a tetrapeptide J. Am. Chem. Soc. 85, 2149-2154
    • (1963) J. Am. Chem. Soc. , vol.85 , pp. 2149-2154
    • Merrifield, R.B.1
  • 41
    • 0001331728 scopus 로고
    • Synthetic peptide vaccine design: Synthesis and properties of a high-density multiple antigenic peptide system
    • Tam, J. P. (1988) Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system Proc. Nat. Acad. Sci. U.S.A. 85, 5409-5413
    • (1988) Proc. Nat. Acad. Sci. U.S.A. , vol.85 , pp. 5409-5413
    • Tam, J.P.1
  • 42
    • 34250842613 scopus 로고    scopus 로고
    • Dendritic α,ε-poly(L-lysine)s as delivery agents for antisense oligonucleotides
    • DOI 10.1007/s11095-006-9231-y
    • Eom, K. D., Park, S. M., Tran, H. D., Kim, M. S., Yu, R. N., and Yoo, H. (2007) Dendritic α,ε-poly(l -lysine)s as delivery agents for antisense oligonucleotides Pharm. Res. 24, 1581-1589 (Pubitemid 46988206)
    • (2007) Pharmaceutical Research , vol.24 , Issue.8 , pp. 1581-1589
    • Eom, K.D.1    Park, S.M.2    Tran, H.D.3    Kim, M.S.4    Yu, R.N.5    Yoo, H.6
  • 43
    • 0036000129 scopus 로고    scopus 로고
    • In vitro gene transfection using dendritic poly(L-lysine)
    • DOI 10.1021/bc015525a
    • Ohsaki, M., Okuda, T., Wada, A., Hirayama, T., Niidome, T., and Aoyagi, H. (2002) In vitro gene transfection using dendritic poly(l -lysine) Bioconjugate Chem. 13, 510-517 (Pubitemid 34527512)
    • (2002) Bioconjugate Chemistry , vol.13 , Issue.3 , pp. 510-517
    • Ohsaki, M.1    Okuda, T.2    Wada, A.3    Hirayama, T.4    Niidome, T.5    Aoyagi, H.6
  • 44
    • 4544313611 scopus 로고    scopus 로고
    • Long circulation of intravenously administered plasmid DNA delivered with dendritic poly(l-lysine) in the blood flow
    • DOI 10.1016/j.jconrel.2004.07.012, PII S0168365904003177
    • Kawano, T., Okuda, T., Aoyagi, H., and Niidome, T. (2004) Long circulation of intravenously administered plasmid DNA delivered with dendritic poly(l -lysine) in the blood flow J. Controlled Release 99, 329-337 (Pubitemid 39222117)
    • (2004) Journal of Controlled Release , vol.99 , Issue.2 , pp. 329-337
    • Kawano, T.1    Okuda, T.2    Aoyagi, H.3    Niidome, T.4
  • 45
    • 0142227090 scopus 로고    scopus 로고
    • Characters of dendritic poly(L-lysine) analogues with the terminal lysines replaced with arginines and histidines as gene carriers in vitro
    • DOI 10.1016/S0142-9612(03)00542-8
    • Okuda, T., Sugiyama, A., Niidome, T., and Aoyagi, H. (2004) Characters of dendritic poly(l -lysine) analogues with the terminal lysines replaced with arginines and histidines as gene carriers in vitro Biomaterials 25, 537-544 (Pubitemid 37329706)
    • (2004) Biomaterials , vol.25 , Issue.3 , pp. 537-544
    • Okuda, T.1    Sugiyama, A.2    Niidome, T.3    Aoyagi, H.4
  • 46
    • 0035869214 scopus 로고    scopus 로고
    • Branched co-polymers of histidine and lysine are efficient carriers of plasmids
    • Chen, Q. R., Zhang, L., Stass, S. A., and Mixson, A. J. (2001) Branched co-polymers of histidine and lysine are efficient carriers of plasmids Nucleic Acids Res. 29, 1334-1340 (Pubitemid 32229461)
    • (2001) Nucleic Acids Research , vol.29 , Issue.6 , pp. 1334-1340
    • Chen, Q.-R.1    Zhang, L.2    Stass, S.A.3    Mixson, A.J.4
  • 47
    • 0037085731 scopus 로고    scopus 로고
    • Optimal transfection with the HK polymer depends on its degree of branching and the pH of endocytic vesicles
    • Chen, Q. R., Zhang, L., Luther, P. W., and Mixson, A. J. (2002) Optimal transfection with the HK polymer depends on its degree of branching and the pH of endocytic vesicles Nucleic Acids Res. 30, 1338-1345 (Pubitemid 34679711)
    • (2002) Nucleic Acids Research , vol.30 , Issue.6 , pp. 1338-1345
    • Chen, Q.-R.1    Zhang, L.2    Luther, P.W.3    Mixson, A.J.4
  • 49
    • 22944469778 scopus 로고    scopus 로고
    • Small interfering RNA targeting Raf-1 inhibits tumor growth in vitro and in vivo
    • DOI 10.1038/sj.cgt.7700831
    • Leng, Q. and Mixson, A. J. (2005) Small interfering RNA targeting Raf-1 inhibits tumor growth in vitro and in vivo Cancer Gene Ther. 12, 682-690 (Pubitemid 41045566)
    • (2005) Cancer Gene Therapy , vol.12 , Issue.8 , pp. 682-690
    • Leng, Q.1    Mixson, A.J.2
  • 50
    • 0031783590 scopus 로고    scopus 로고
    • Synthesis and physicochemical properties of lipophilic polyamide dendrimers
    • DOI 10.1023/A:1011935406664
    • Sakthivel, T., Toth, I., and Florence, A. T. (1998) Synthesis and physicochemical properties of lipophilic polyamide dendrimers Pharm. Res. 15, 776-782 (Pubitemid 28275657)
    • (1998) Pharmaceutical Research , vol.15 , Issue.5 , pp. 776-782
    • Sakthivel, T.1    Toth, I.2    Florence, A.T.3
  • 51
    • 0034605687 scopus 로고    scopus 로고
    • DNA transfection and transfected cell viability using amphipathic asymmetric dendrimers
    • Shah, D. S., Sakthivel, T., Toth, I., Florence, A. T., and Wilderspin, A. F. (2000) DNA transfection and transfected cell viability using amphipathic asymmetric dendrimers Int. J. Pharm. 208, 41-48
    • (2000) Int. J. Pharm. , vol.208 , pp. 41-48
    • Shah, D.S.1    Sakthivel, T.2    Toth, I.3    Florence, A.T.4    Wilderspin, A.F.5
  • 53
    • 0027655718 scopus 로고
    • Polyamidoamine cascade polymers mediate efficient transfection of cells in culture
    • Haensler, J. and Szoka, F. C., Jr. (1993) Polyamidoamine cascade polymers mediate efficient transfection of cells in culture Bioconjugate Chem. 4, 372-379
    • (1993) Bioconjugate Chem. , vol.4 , pp. 372-379
    • Haensler, J.1    Szoka Jr., F.C.2
  • 54
    • 0029945799 scopus 로고    scopus 로고
    • Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers
    • DOI 10.1093/nar/24.11.2176
    • Bielinska, A., Kukowska-Latallo, J. F., Johnson, J., Tomalia, D. A., and Baker, J. R. (1996) Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers Nucleic Acids Res. 24, 2176-2182 (Pubitemid 26174562)
    • (1996) Nucleic Acids Research , vol.24 , Issue.11 , pp. 2176-2182
    • Bielinska, A.1    Kukowska-Latallo, J.F.2    Johnson, J.3    Tomalia, D.A.4    Baker Jr., J.R.5
  • 55
    • 0030293017 scopus 로고    scopus 로고
    • In vitro gene delivery by degraded polyamidoamine dendrimers
    • DOI 10.1021/bc9600630
    • Tang, M. X., Redemann, C. T., and Szoka, F. C., Jr. (1996) In vitro gene delivery by degraded polyamidoamine dendrimers Bioconjugate Chem. 7, 703-714 (Pubitemid 27012712)
    • (1996) Bioconjugate Chemistry , vol.7 , Issue.6 , pp. 703-714
    • Tang, M.X.1    Redemann, C.T.2    Szoka Jr., F.C.3
  • 56
    • 0033404268 scopus 로고    scopus 로고
    • PAMAM dendrimers as delivery agents for antisense oligonucleotides
    • Yoo, H., Sazani, P., and Juliano, R. L. (1999) PAMAM dendrimers as delivery agents for antisense oligonucleotides Pharm. Res. 16, 1799-1804 (Pubitemid 30040693)
    • (1999) Pharmaceutical Research , vol.16 , Issue.12 , pp. 1799-1804
    • Yoo, H.1    Sazani, P.2    Juliano, R.L.3
  • 57
    • 4644335136 scopus 로고    scopus 로고
    • Enhanced transfection efficiency of PAMAM dendrimer by surface modification with l-arginine
    • DOI 10.1016/j.jconrel.2004.07.027, PII S0168365904003633
    • Choi, J. S., Nam, K., Park, J.-y., Kim, J.-B., Lee, J.-K., and Park, J.-s. (2004) Enhanced transfection efficiency of PAMAM dendrimer by surface modification with l -arginine J. Controlled Release 99, 445-456 (Pubitemid 39296913)
    • (2004) Journal of Controlled Release , vol.99 , Issue.3 , pp. 445-456
    • Choi, J.S.1    Nam, K.2    Park, J.-Y.3    Kim, J.-B.4    Lee, J.-K.5    Park, J.-S.6
  • 58
    • 51649131354 scopus 로고    scopus 로고
    • Evaluation of generations 2, 3 and 4 arginine modified PAMAM dendrimers for gene delivery
    • Nam, H. Y., Hahn, H. J., Nam, K., Choi, W.-H., Jeong, Y., Kim, D.-E., and Park, J.-S. (2008) Evaluation of generations 2, 3 and 4 arginine modified PAMAM dendrimers for gene delivery Int. J. Pharm. 363, 199-205
    • (2008) Int. J. Pharm. , vol.363 , pp. 199-205
    • Nam, H.Y.1    Hahn, H.J.2    Nam, K.3    Choi, W.-H.4    Jeong, Y.5    Kim, D.-E.6    Park, J.-S.7
  • 59
    • 79959267067 scopus 로고    scopus 로고
    • Synthesis of PAMAM dendrimer derivatives with enhanced buffering capacity and remarkable gene transfection efficiency
    • Yu, G. S., Bae, Y. M., Choi, H., Kong, B., Choi, I. S., and Choi, J. S. (2011) Synthesis of PAMAM dendrimer derivatives with enhanced buffering capacity and remarkable gene transfection efficiency Bioconjugate Chem. 22, 1046-1055
    • (2011) Bioconjugate Chem. , vol.22 , pp. 1046-1055
    • Yu, G.S.1    Bae, Y.M.2    Choi, H.3    Kong, B.4    Choi, I.S.5    Choi, J.S.6
  • 60
    • 0035997509 scopus 로고    scopus 로고
    • The lower-generation polypropylenimine dendrimers are effective gene-transfer agents
    • DOI 10.1023/A:1016458104359
    • Zinselmeyer, B. H., Mackay, S. P., Schatzlein, A. G., and Uchegbu, I. F. (2002) The lower-generation polypropylenimine dendrimers are effective gene-transfer agents Pharm. Res. 19, 960-967 (Pubitemid 34808705)
    • (2002) Pharmaceutical Research , vol.19 , Issue.7 , pp. 960-967
    • Zinselmeyer, B.H.1    Mackay, S.P.2    Schatzlein, A.G.3    Uchegbu, I.F.4
  • 62
    • 56649086656 scopus 로고    scopus 로고
    • Oligoethylenimine-grafted polypropylenimine dendrimers as degradable and biocompatible synthetic vectors for gene delivery
    • Russ, V., Gunther, M., Halama, A., Ogris, M., and Wagner, E. (2008) Oligoethylenimine-grafted polypropylenimine dendrimers as degradable and biocompatible synthetic vectors for gene delivery J. Controlled Release 132, 131-140
    • (2008) J. Controlled Release , vol.132 , pp. 131-140
    • Russ, V.1    Gunther, M.2    Halama, A.3    Ogris, M.4    Wagner, E.5
  • 63
    • 0033585470 scopus 로고    scopus 로고
    • Branched cationic peptides for gene delivery: Role of type and number of cationic residues in formation and in vitro activity of DNA polyplexes
    • DOI 10.1089/10430349950019101
    • Plank, C., Tang, M. X., Wolfe, A. R., and Szoka, F. C., Jr. (1999) Branched cationic peptides for gene delivery: role of type and number of cationic residues in formation and in vitro activity of DNA polyplexes Hum. Gene Ther. 10, 319-332 (Pubitemid 29070645)
    • (1999) Human Gene Therapy , vol.10 , Issue.2 , pp. 319-332
    • Plank, C.1    Tang, M.X.2    Wolfe, A.R.3    Szoka Jr., F.C.4
  • 65
    • 0025313130 scopus 로고
    • Transferrin-polycation-mediated introduction of DNA into human leukemic cells: Stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels
    • Cotten, M., Langle-Rouault, F., Kirlappos, H., Wagner, E., Mechtler, K., Zenke, M., Beug, H., and Birnstiel, M. L. (1990) Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels Proc. Natl. Acad. Sci. U.S.A. 87, 4033-4037
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 4033-4037
    • Cotten, M.1    Langle-Rouault, F.2    Kirlappos, H.3    Wagner, E.4    Mechtler, K.5    Zenke, M.6    Beug, H.7    Birnstiel, M.L.8
  • 66
    • 0030890748 scopus 로고    scopus 로고
    • Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers
    • DOI 10.1021/bi9618474
    • Wyman, T. B., Nicol, F., Zelphati, O., Scaria, P. V., Plank, C., and Szoka, F. C., Jr. (1997) Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers Biochemistry 36, 3008-3017 (Pubitemid 27138586)
    • (1997) Biochemistry , vol.36 , Issue.10 , pp. 3008-3017
    • Wyman, T.B.1    Nicol, F.2    Zelphati, O.3    Scaria, P.V.4    Plank, C.5    Szoka Jr., F.C.6
  • 67
    • 0034616214 scopus 로고    scopus 로고
    • A potent new class of reductively activated peptide gene delivery agents
    • DOI 10.1074/jbc.275.14.9970
    • McKenzie, D. L., Kwok, K. Y., and Rice, K. G. (2000) A potent new class of reductively activated peptide gene delivery agents J. Biol. Chem. 275, 9970-9977 (Pubitemid 30202043)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.14 , pp. 9970-9977
    • McKenzie, D.L.1    Kwok, K.Y.2    Rice, K.G.3
  • 68
    • 0033646067 scopus 로고    scopus 로고
    • Low molecular weight disulfide cross-linking peptides as nonviral gene delivery carriers
    • McKenzie, D. L., Smiley, E., Kwok, K. Y., and Rice, K. G. (2000) Low molecular weight disulfide cross-linking peptides as nonviral gene delivery carriers Bioconjugate Chem. 11, 901-909
    • (2000) Bioconjugate Chem. , vol.11 , pp. 901-909
    • McKenzie, D.L.1    Smiley, E.2    Kwok, K.Y.3    Rice, K.G.4
  • 69
    • 0038563848 scopus 로고    scopus 로고
    • Vectors based on reducible polycations facilitate intracellular release of nucleic acids
    • DOI 10.1002/jgm.331
    • Read, M. L., Bremner, K. H., Oupicky, D., Green, N. K., Searle, P. F., and Seymour, L. W. (2003) Vectors based on reducible polycations facilitate intracellular release of nucleic acids J. Gene Med. 5, 232-245 (Pubitemid 40310377)
    • (2003) Journal of Gene Medicine , vol.5 , Issue.3 , pp. 232-245
    • Read, M.L.1    Bremner, K.H.2    Oupicky, D.3    Green, N.K.4    Searle, P.F.5    Seymour, L.W.6
  • 70
    • 77952241478 scopus 로고    scopus 로고
    • RNA interference in vitro and in vivo using an arginine peptide/siRNA complex system
    • Kim, S. W., Kim, N. Y., Choi, Y. B., Park, S. H., Yang, J. M., and Shin, S. (2010) RNA interference in vitro and in vivo using an arginine peptide/siRNA complex system J. Controlled Release 143, 335-343
    • (2010) J. Controlled Release , vol.143 , pp. 335-343
    • Kim, S.W.1    Kim, N.Y.2    Choi, Y.B.3    Park, S.H.4    Yang, J.M.5    Shin, S.6
  • 71
    • 76249103305 scopus 로고    scopus 로고
    • Degradation of poly(glycoamidoamine) DNA delivery vehicles: Polyamide hydrolysis at physiological conditions promotes DNA release
    • Liu, Y. and Reineke, T. M. (2010) Degradation of poly(glycoamidoamine) DNA delivery vehicles: polyamide hydrolysis at physiological conditions promotes DNA release Biomacromolecules 11, 316-325
    • (2010) Biomacromolecules , vol.11 , pp. 316-325
    • Liu, Y.1    Reineke, T.M.2
  • 72
    • 76249089096 scopus 로고    scopus 로고
    • Amide spacing influences pDNA binding of poly(amidoamine)s
    • Prevette, L. E., Lynch, M. L., and Reineke, T. M. (2010) Amide spacing influences pDNA binding of poly(amidoamine)s Biomacromolecules 11, 326-332
    • (2010) Biomacromolecules , vol.11 , pp. 326-332
    • Prevette, L.E.1    Lynch, M.L.2    Reineke, T.M.3
  • 73
    • 77953259088 scopus 로고    scopus 로고
    • Poly(glycoamidoamine) vehicles promote pDNA uptake through multiple routes and efficient gene expression via caveolae-mediated endocytosis
    • McLendon, P. M., Fichter, K. M., and Reineke, T. M. (2010) Poly(glycoamidoamine) vehicles promote pDNA uptake through multiple routes and efficient gene expression via caveolae-mediated endocytosis Mol. Pharmaceutics 7, 738-750
    • (2010) Mol. Pharmaceutics , vol.7 , pp. 738-750
    • McLendon, P.M.1    Fichter, K.M.2    Reineke, T.M.3
  • 74
    • 78650770524 scopus 로고    scopus 로고
    • Polymers for control freaks: Sequence-defined poly(amidoamine)s and their biomedical applications
    • Hartmann, L. (2011) Polymers for control freaks: sequence-defined poly(amidoamine)s and their biomedical applications Macromol. Chem. Phys. 212, 8-13
    • (2011) Macromol. Chem. Phys. , vol.212 , pp. 8-13
    • Hartmann, L.1
  • 75
    • 69249207273 scopus 로고    scopus 로고
    • Precision polymers: Monodisperse, monomer-sequence-defined segments to target future demands of polymers in medicine
    • Hartmann, L. and Börner, H. G. (2009) Precision polymers: monodisperse, monomer-sequence-defined segments to target future demands of polymers in medicine Adv. Mater. 21, 3425-3431
    • (2009) Adv. Mater. , vol.21 , pp. 3425-3431
    • Hartmann, L.1    Börner, H.G.2
  • 76
    • 53849102257 scopus 로고    scopus 로고
    • Tailor-made poly(amidoamine)s for controlled complexation and condensation of DNA
    • Hartmann, L., Hafele, S., Peschka-Suss, R., Antonietti, M., and Borner, H. G. (2008) Tailor-made poly(amidoamine)s for controlled complexation and condensation of DNA Chemistry 14, 2025-2033
    • (2008) Chemistry , vol.14 , pp. 2025-2033
    • Hartmann, L.1    Hafele, S.2    Peschka-Suss, R.3    Antonietti, M.4    Borner, H.G.5
  • 77
    • 36048937620 scopus 로고    scopus 로고
    • Sequence positioning of disulfide linkages to program the degradation of monodisperse poly(amidoamines)
    • DOI 10.1021/ma071427u
    • Hartmann, L., Häfele, S., Peschka-Süss, R., Antonietti, M., and Börner, H. G. (2007) Sequence positioning of disulfide linkages to program the degradation of monodisperse poly(amidoamines) Macromolecules 40, 7771-7776 (Pubitemid 350099678)
    • (2007) Macromolecules , vol.40 , Issue.22 , pp. 7771-7776
    • Hartmann, L.1    Hafele, S.2    Peschka-Suss, R.3    Antonietti, M.4    Borner, H.G.5
  • 78
    • 33646356469 scopus 로고    scopus 로고
    • Solid-phase supported polymer synthesis of sequence-defined, multifunctional poly(amidoamines)
    • DOI 10.1021/bm050884k
    • Hartmann, L., Krause, E., Antonietti, M., and Borner, H. G. (2006) Solid-phase supported polymer synthesis of sequence-defined, multifunctional poly(amidoamines) Biomacromolecules 7, 1239-1244 (Pubitemid 43670812)
    • (2006) Biomacromolecules , vol.7 , Issue.4 , pp. 1239-1244
    • Hartmann, L.1    Krause, E.2    Antonietti, M.3    Borner, H.G.4
  • 79
    • 78651446668 scopus 로고    scopus 로고
    • Precise positioning of chiral building blocks in monodisperse, sequence-defined polyamides
    • Mosca, S., Wojcik, F., and Hartmann, L. (2011) Precise positioning of chiral building blocks in monodisperse, sequence-defined polyamides Macromol. Rapid Commun. 32, 197-202
    • (2011) Macromol. Rapid Commun. , vol.32 , pp. 197-202
    • Mosca, S.1    Wojcik, F.2    Hartmann, L.3
  • 80
    • 79953173288 scopus 로고    scopus 로고
    • Novel Fmoc-polyamino acids for solid-phase synthesis of defined polyamidoamines
    • Schaffert, D., Badgujar, N., and Wagner, E. (2011) Novel Fmoc-polyamino acids for solid-phase synthesis of defined polyamidoamines Org. Lett. 13, 1586-1589
    • (2011) Org. Lett. , vol.13 , pp. 1586-1589
    • Schaffert, D.1    Badgujar, N.2    Wagner, E.3
  • 83
    • 0035955150 scopus 로고    scopus 로고
    • Dimerizable cationic detergents with a low cmc condense plasmid DNA into nanometric particles and transfect cells in culture
    • DOI 10.1021/ja015867r
    • Dauty, E., Remy, J.-S., Blessing, T., and Behr, J.-P. (2001) Dimerizable cationic detergents with a low cmc condense plasmid DNA into nanometric particles and transfect cells in culture J. Am. Chem. Soc. 123, 9227-9234 (Pubitemid 32900293)
    • (2001) Journal of the American Chemical Society , vol.123 , Issue.38 , pp. 9227-9234
    • Dauty, E.1    Remy, J.-S.2    Blessing, T.3    Behr, J.-P.4
  • 84
    • 70350077962 scopus 로고    scopus 로고
    • Synthetic viruslike particles for targeted gene delivery to αvβ3 integrin-presenting endothelial cells
    • Zuber, G., Dontenwill, M., and Behr, J.-P. (2009) Synthetic viruslike particles for targeted gene delivery to αvβ3 integrin-presenting endothelial cells Mol. Pharmaceutics 6, 1544-1552
    • (2009) Mol. Pharmaceutics , vol.6 , pp. 1544-1552
    • Zuber, G.1    Dontenwill, M.2    Behr, J.-P.3
  • 86
    • 79954552079 scopus 로고    scopus 로고
    • Design, synthesis and evaluation of spermine-based pH-sensitive amphiphilic gene delivery systems: Multifunctional non-viral gene carriers
    • Xu, R. and Lu, Z.-R. (2011) Design, synthesis and evaluation of spermine-based pH-sensitive amphiphilic gene delivery systems: multifunctional non-viral gene carriers Sci. China Chem. 54, 359-368
    • (2011) Sci. China Chem. , vol.54 , pp. 359-368
    • Xu, R.1    Lu, Z.-R.2
  • 87
    • 77957952646 scopus 로고    scopus 로고
    • New amphiphilic carriers forming pH-sensitive nanoparticles for nucleic acid delivery
    • Xu, R., Wang, X.-L., and Lu, Z.-R. (2010) New amphiphilic carriers forming pH-sensitive nanoparticles for nucleic acid delivery Langmuir 26, 13874-13882
    • (2010) Langmuir , vol.26 , pp. 13874-13882
    • Xu, R.1    Wang, X.-L.2    Lu, Z.-R.3
  • 88
    • 61349171236 scopus 로고    scopus 로고
    • A peptide-targeted delivery system with pH-sensitive amphiphilic cell membrane disruption for efficient receptor-mediated siRNA delivery
    • Wang, X.-L., Xu, R., and Lu, Z.-R. (2009) A peptide-targeted delivery system with pH-sensitive amphiphilic cell membrane disruption for efficient receptor-mediated siRNA delivery J. Controlled Release 134, 207-213
    • (2009) J. Controlled Release , vol.134 , pp. 207-213
    • Wang, X.-L.1    Xu, R.2    Lu, Z.-R.3
  • 89
    • 67249148163 scopus 로고    scopus 로고
    • Targeted systemic delivery of a therapeutic siRNA with a multifunctional carrier controls tumor proliferation in mice
    • Wang, X.-L., Xu, R., Wu, X., Gillespie, D., Jensen, R., and Lu, Z.-R. (2009) Targeted systemic delivery of a therapeutic siRNA with a multifunctional carrier controls tumor proliferation in mice Mol. Pharmaceutics 6, 738-746
    • (2009) Mol. Pharmaceutics , vol.6 , pp. 738-746
    • Wang, X.-L.1    Xu, R.2    Wu, X.3    Gillespie, D.4    Jensen, R.5    Lu, Z.-R.6
  • 90
    • 71249151558 scopus 로고    scopus 로고
    • Hydrophobically modified oligoethylenimines as highly efficient transfection agents for siRNA delivery
    • Philipp, A., Zhao, X., Tarcha, P., Wagner, E., and Zintchenko, A. (2009) Hydrophobically modified oligoethylenimines as highly efficient transfection agents for siRNA delivery Bioconjugate Chem. 20, 2055-2061
    • (2009) Bioconjugate Chem. , vol.20 , pp. 2055-2061
    • Philipp, A.1    Zhao, X.2    Tarcha, P.3    Wagner, E.4    Zintchenko, A.5
  • 92
    • 77950476006 scopus 로고    scopus 로고
    • Angiogenic vessel-targeting DDS by liposomalized oligopeptides
    • Asai, T. and Oku, N. (2010) Angiogenic vessel-targeting DDS by liposomalized oligopeptides Methods Mol. Biol. 605, 335-347
    • (2010) Methods Mol. Biol. , vol.605 , pp. 335-347
    • Asai, T.1    Oku, N.2
  • 99
    • 79955604155 scopus 로고    scopus 로고
    • Poly(I:C)-mediated tumor growth suppression in EGF-receptor overexpressing tumors using EGF-polyethylene glycol-linear polyethylenimine as carrier
    • Schaffert, D., Kiss, M., Rodl, W., Shir, A., Levitzki, A., Ogris, M., and Wagner, E. (2011) Poly(I:C)-mediated tumor growth suppression in EGF-receptor overexpressing tumors using EGF-polyethylene glycol-linear polyethylenimine as carrier Pharm. Res. 28, 731-741
    • (2011) Pharm. Res. , vol.28 , pp. 731-741
    • Schaffert, D.1    Kiss, M.2    Rodl, W.3    Shir, A.4    Levitzki, A.5    Ogris, M.6    Wagner, E.7
  • 100
    • 32344451398 scopus 로고    scopus 로고
    • ω-Hydrazino linear polyethylenimine: A monoconjugation building block for nucleic acid delivery
    • DOI 10.1002/cbic.200500349
    • Pons, B., Mouhoubi, L., Adib, A., Godzina, P., Behr, J. P., and Zuber, G. (2006) ω-Hydrazino linear polyethylenimine: a monoconjugation building block for nucleic acid delivery Chembiochem 7, 303-309 (Pubitemid 43220944)
    • (2006) ChemBioChem , vol.7 , Issue.2 , pp. 303-309
    • Pons, B.1    Mouhoubi, L.2    Adib, A.3    Godzina, P.4    Behr, J.-P.5    Zuber, G.6
  • 101
    • 51649102031 scopus 로고    scopus 로고
    • Click chemistry, a powerful tool for pharmaceutical sciences
    • Hein, C., Liu, X.-M., and Wang, D. (2008) Click chemistry, a powerful tool for pharmaceutical sciences Pharm. Res. 25, 2216-2230
    • (2008) Pharm. Res. , vol.25 , pp. 2216-2230
    • Hein, C.1    Liu, X.-M.2    Wang, D.3
  • 102
    • 43449108552 scopus 로고    scopus 로고
    • Efficient construction of therapeutics, bioconjugates, biomaterials and bioactive surfaces using azide-alkyne "click" chemistry
    • Lutz, J.-F. and Zarafshani, Z. (2008) Efficient construction of therapeutics, bioconjugates, biomaterials and bioactive surfaces using azide-alkyne "click" chemistry Adv. Drug Delivery Rev. 60, 958-970
    • (2008) Adv. Drug Delivery Rev. , vol.60 , pp. 958-970
    • Lutz, J.-F.1    Zarafshani, Z.2
  • 103
    • 34547272503 scopus 로고    scopus 로고
    • The growing applications of click chemistry
    • Moses, J. E. and Moorhouse, A. D. (2007) The growing applications of click chemistry Chem. Soc. Rev. 36, 1249-1262
    • (2007) Chem. Soc. Rev. , vol.36 , pp. 1249-1262
    • Moses, J.E.1    Moorhouse, A.D.2
  • 104
    • 77955575793 scopus 로고    scopus 로고
    • High density orthogonal surface immobilization via photoactivated copper-free click chemistry
    • Orski, S. V., Poloukhtine, A. A., Arumugam, S., Mao, L., Popik, V. V., and Locklin, J. (2010) High density orthogonal surface immobilization via photoactivated copper-free click chemistry J. Am. Chem. Soc. 132, 11024-11026
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 11024-11026
    • Orski, S.V.1    Poloukhtine, A.A.2    Arumugam, S.3    Mao, L.4    Popik, V.V.5    Locklin, J.6
  • 105
    • 0000096835 scopus 로고    scopus 로고
    • Click chemistry: Diverse chemical function from a few good reactions
    • Kolb, H. C., Finn, M. G., and Sharpless, K. B. (2001) Click chemistry: diverse chemical function from a few good reactions Angew. Chem. Int. Ed. 40, 2004-2021
    • (2001) Angew. Chem. Int. Ed. , vol.40 , pp. 2004-2021
    • Kolb, H.C.1    Finn, M.G.2    Sharpless, K.B.3
  • 106
    • 0037099395 scopus 로고    scopus 로고
    • A stepwise huisgen cycloaddition process: Copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes
    • DOI 10.1002/1521-3773(20020715)41:14<2596::AID-ANIE2596>3.0.CO;2-4
    • Rostovtsev, V. V., Green, L. G., Fokin, V. V., and Sharpless, K. B. (2002) A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes Angew. Chem. Int. Ed. 41, 2596-2599 (Pubitemid 34803480)
    • (2002) Angewandte Chemie - International Edition , vol.41 , Issue.14 , pp. 2596-2599
    • Rostovtsev, V.V.1    Green, L.G.2    Fokin, V.V.3    Sharpless, K.B.4
  • 107
    • 0037012920 scopus 로고    scopus 로고
    • Peptidotriazoles on solid phase: [1,2,3]-Triazoles by regiospecific copper(I)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides
    • DOI 10.1021/jo011148j
    • Tornøe, C. W., Christensen, C., and Meldal, M. (2002) Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(I)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides J. Org. Chem. 67, 3057-3064 (Pubitemid 34457265)
    • (2002) Journal of Organic Chemistry , vol.67 , Issue.9 , pp. 3057-3064
    • Tornoe, C.W.1    Christensen, C.2    Meldal, M.3
  • 108
    • 70350304285 scopus 로고    scopus 로고
    • A "click chemistry" approach to the efficient synthesis of multiple imaging probes derived from a single precursor
    • Mindt, T. L., Muller, C., Stuker, F., Salazar, J.-F., Hohn, A., Mueggler, T., Rudin, M., and Schibli, R. (2009) A "click chemistry" approach to the efficient synthesis of multiple imaging probes derived from a single precursor Bioconjugate Chem. 20, 1940-1949
    • (2009) Bioconjugate Chem. , vol.20 , pp. 1940-1949
    • Mindt, T.L.1    Muller, C.2    Stuker, F.3    Salazar, J.-F.4    Hohn, A.5    Mueggler, T.6    Rudin, M.7    Schibli, R.8
  • 109
    • 52449093614 scopus 로고    scopus 로고
    • Click chemistry for high-density biofunctionalization of mesoporous silica
    • Schlossbauer, A., Schaffert, D., Kecht, J., Wagner, E., and Bein, T. (2008) Click chemistry for high-density biofunctionalization of mesoporous silica J. Am. Chem. Soc. 130, 12558-12559
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 12558-12559
    • Schlossbauer, A.1    Schaffert, D.2    Kecht, J.3    Wagner, E.4    Bein, T.5
  • 111
    • 36849070485 scopus 로고    scopus 로고
    • Degradable-brushed pHEMA-pDMAEMA synthesized via ATRP and click chemistry for gene delivery
    • DOI 10.1021/bc0701186
    • Jiang, X., Lok, M. C., and Hennink, W. E. (2007) Degradable-brushed pHEMA-pDMAEMA synthesized via ATRP and click chemistry for gene delivery Bioconjugate Chem. 18, 2077-2084 (Pubitemid 350220011)
    • (2007) Bioconjugate Chemistry , vol.18 , Issue.6 , pp. 2077-2084
    • Jiang, X.1    Lok, M.C.2    Hennink, W.E.3
  • 112
    • 77953648010 scopus 로고    scopus 로고
    • A polycation scaffold presenting tunable "click" sites: Conjugation to carbohydrate ligands and examination of hepatocyte-targeted pDNA delivery
    • Lee, C.-C., Grandinetti, G., McLendon, P. M., and Reineke, T. M. (2010) A polycation scaffold presenting tunable "click" sites: conjugation to carbohydrate ligands and examination of hepatocyte-targeted pDNA delivery Macromol. Biosci. 10, 585-598
    • (2010) Macromol. Biosci. , vol.10 , pp. 585-598
    • Lee, C.-C.1    Grandinetti, G.2    McLendon, P.M.3    Reineke, T.M.4
  • 113
    • 77958170934 scopus 로고    scopus 로고
    • Novel reduction-responsive cross-linked polyethylenimine derivatives by click chemistry for nonviral gene delivery
    • Liu, J., Jiang, X., Xu, L., Wang, X., Hennink, W. E., and Zhuo, R. (2010) Novel reduction-responsive cross-linked polyethylenimine derivatives by click chemistry for nonviral gene delivery Bioconjugate Chem. 21, 1827-1835
    • (2010) Bioconjugate Chem. , vol.21 , pp. 1827-1835
    • Liu, J.1    Jiang, X.2    Xu, L.3    Wang, X.4    Hennink, W.E.5    Zhuo, R.6
  • 114
    • 33745674022 scopus 로고    scopus 로고
    • Trehalose click polymers inhibit nanoparticle aggregation and promote pDNA delivery in serum
    • DOI 10.1021/ja0585580
    • Srinivasachari, S., Liu, Y., Zhang, G., Prevette, L., and Reineke, T. M. (2006) Trehalose click polymers inhibit nanoparticle aggregation and promote pDNA delivery in serum J. Am. Chem. Soc. 128, 8176-8184 (Pubitemid 43967762)
    • (2006) Journal of the American Chemical Society , vol.128 , Issue.25 , pp. 8176-8184
    • Srinivasachari, S.1    Liu, Y.2    Zhang, G.3    Prevette, L.4    Reineke, T.M.5
  • 115
    • 57549083059 scopus 로고    scopus 로고
    • Versatile supramolecular pDNA vehicles via "click polymerization" of β-cyclodextrin with oligoethyleneamines
    • Srinivasachari, S. and Reineke, T. M. (2009) Versatile supramolecular pDNA vehicles via "click polymerization" of β-cyclodextrin with oligoethyleneamines Biomaterials 30, 928-938
    • (2009) Biomaterials , vol.30 , pp. 928-938
    • Srinivasachari, S.1    Reineke, T.M.2
  • 116
    • 71249129936 scopus 로고    scopus 로고
    • Synthesis and applications of biomedical and pharmaceutical polymers via click chemistry methodologies
    • van Dijk, M., Rijkers, D. T. S., Liskamp, R. M. J., van Nostrum, C. F., and Hennink, W. E. (2009) Synthesis and applications of biomedical and pharmaceutical polymers via click chemistry methodologies Bioconjugate Chem. 20, 2001-2016
    • (2009) Bioconjugate Chem. , vol.20 , pp. 2001-2016
    • Van Dijk, M.1    Rijkers, D.T.S.2    Liskamp, R.M.J.3    Van Nostrum, C.F.4    Hennink, W.E.5
  • 117
    • 55849108128 scopus 로고    scopus 로고
    • Synthesis and characterization of poly(amido amine) dendrimer containing fluorene as a core chromophore
    • Lee, J. W., Kim, H. J., Han, S. C., Kim, J. H., and Jin, S.-H. (2008) Synthesis and characterization of poly(amido amine) dendrimer containing fluorene as a core chromophore J. Nanosci. Nanotechnol. 8, 4635-4639
    • (2008) J. Nanosci. Nanotechnol. , vol.8 , pp. 4635-4639
    • Lee, J.W.1    Kim, H.J.2    Han, S.C.3    Kim, J.H.4    Jin, S.-H.5
  • 118
    • 38349135129 scopus 로고    scopus 로고
    • Designing poly(amido amine) dendrimers containing core diversities by click chemistry of the propargyl focal point poly(amido amine) dendrons
    • Lee, J. W., Kim, H. J., Han, S. C., Kim, J. H., and Jin, S.-H. (2008) Designing poly(amido amine) dendrimers containing core diversities by click chemistry of the propargyl focal point poly(amido amine) dendrons J. Polym. Sci. Part A: Polym. Chem. 46, 1083-1097
    • (2008) J. Polym. Sci. Part A: Polym. Chem. , vol.46 , pp. 1083-1097
    • Lee, J.W.1    Kim, H.J.2    Han, S.C.3    Kim, J.H.4    Jin, S.-H.5
  • 119
    • 79958815062 scopus 로고    scopus 로고
    • Epidermal growth factor-PEG functionalized PAMAM-pentaethylenehexamine dendron for targeted gene delivery produced by click chemistry
    • Yu, H., Nie, Y., Dohmen, C., Li, Y., and Wagner, E. (2011) Epidermal growth factor-PEG functionalized PAMAM-pentaethylenehexamine dendron for targeted gene delivery produced by click chemistry Biomacromolecules 12, 2039-2047
    • (2011) Biomacromolecules , vol.12 , pp. 2039-2047
    • Yu, H.1    Nie, Y.2    Dohmen, C.3    Li, Y.4    Wagner, E.5
  • 120
    • 79951946268 scopus 로고    scopus 로고
    • Copper-free click conjugation of methotrexate to a PAMAM dendrimer platform
    • Huang, B., Desai, A., Zong, H., Tang, S., Leroueil, P., and Baker, J. R., Jr. (2011) Copper-free click conjugation of methotrexate to a PAMAM dendrimer platform Tetrahedron Lett. 52, 1411-1414
    • (2011) Tetrahedron Lett. , vol.52 , pp. 1411-1414
    • Huang, B.1    Desai, A.2    Zong, H.3    Tang, S.4    Leroueil, P.5    Baker Jr., J.R.6
  • 121
    • 78650320598 scopus 로고    scopus 로고
    • Non-nucleoside building blocks for copper-assisted and copper-free click chemistry for the efficient synthesis of RNA conjugates
    • Jayaprakash, K. N., Peng, C. G., Butler, D., Varghese, J. P., Maier, M. A., Rajeev, K. G., and Manoharan, M. (2010) Non-nucleoside building blocks for copper-assisted and copper-free click chemistry for the efficient synthesis of RNA conjugates Org. Lett. 12, 5410-5413
    • (2010) Org. Lett. , vol.12 , pp. 5410-5413
    • Jayaprakash, K.N.1    Peng, C.G.2    Butler, D.3    Varghese, J.P.4    Maier, M.A.5    Rajeev, K.G.6    Manoharan, M.7
  • 123
    • 0027944205 scopus 로고
    • Synthesis of proteins by native chemical ligation
    • Dawson, P., Muir, T., Clark-Lewis, I., and Kent, S. (1994) Synthesis of proteins by native chemical ligation Science 266, 776-779 (Pubitemid 24359280)
    • (1994) Science , vol.266 , Issue.5186 , pp. 776-779
    • Dawson, P.E.1    Muir, T.W.2    Clark-Lewis, I.3    Kent, S.B.H.4
  • 125
    • 14044252938 scopus 로고    scopus 로고
    • Toward synthetic viruses: Endosomal pH-Triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo
    • DOI 10.1016/j.ymthe.2004.11.006, PII S1525001604015321
    • Walker, G. F., Fella, C., Pelisek, J., Fahrmeir, J., Boeckle, S., Ogris, M., and Wagner, E. (2005) Toward synthetic viruses: endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo Mol. Ther. 11, 418-425 (Pubitemid 40277318)
    • (2005) Molecular Therapy , vol.11 , Issue.3 , pp. 418-425
    • Walker, G.F.1    Fella, C.2    Pelisek, J.3    Fahrmeir, J.4    Boeckle, S.5    Ogris, M.6    Wagner, E.7
  • 126
    • 34547153677 scopus 로고    scopus 로고
    • An acetal-based PEGylation reagent for pH-sensitive shielding of DNA polyplexes
    • DOI 10.1021/bc060327a
    • Knorr, V., Allmendinger, L., Walker, G. F., Paintner, F. F., and Wagner, E. (2007) An acetal-based PEGylation reagent for pH-sensitive shielding of DNA polyplexes Bioconjugate Chem. 18, 1218-1225 (Pubitemid 47122645)
    • (2007) Bioconjugate Chemistry , vol.18 , Issue.4 , pp. 1218-1225
    • Knorr, V.1    Allmendinger, L.2    Walker, G.F.3    Paintner, F.F.4    Wagner, E.5
  • 127
    • 47249130263 scopus 로고    scopus 로고
    • Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding
    • Fella, C., Walker, G. F., Ogris, M., and Wagner, E. (2008) Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding Eur. J. Pharm. Sci 34, 309-320
    • (2008) Eur. J. Pharm. Sci , vol.34 , pp. 309-320
    • Fella, C.1    Walker, G.F.2    Ogris, M.3    Wagner, E.4
  • 129
    • 78549278709 scopus 로고    scopus 로고
    • Pyridylhydrazone-based PEGylation for pH-reversible lipopolyplex shielding
    • Nie, Y., Günther, M., Gu, Z., and Wagner, E. (2011) Pyridylhydrazone-based PEGylation for pH-reversible lipopolyplex shielding Biomaterials 32, 858-869
    • (2011) Biomaterials , vol.32 , pp. 858-869
    • Nie, Y.1    Günther, M.2    Gu, Z.3    Wagner, E.4
  • 130
    • 0025398291 scopus 로고
    • Biological activity of oligonucleotide-poly(l -lysine) conjugates: Mechanism of cell uptake 381
    • Leonetti, J. P., Degols, G., and Lebleu, B. (1990) Biological activity of oligonucleotide-poly(l -lysine) conjugates: mechanism of cell uptake 381 Bioconjugate Chem. 1, 149-153
    • (1990) Bioconjugate Chem. , vol.1 , pp. 149-153
    • Leonetti, J.P.1    Degols, G.2    Lebleu, B.3
  • 131
    • 0242662545 scopus 로고    scopus 로고
    • A new pH-responsive and glutathione-reactive, endosomal membrane-disruptive polymeric carrier for intracellular delivery of biomolecular drugs
    • DOI 10.1016/j.jconrel.2003.06.001
    • Bulmus, V., Woodward, M., Lin, L., Murthy, N., Stayton, P., and Hoffman, A. (2003) A new pH-responsive and glutathione-reactive, endosomal membrane-disruptive polymeric carrier for intracellular delivery of biomolecular drugs J. Controlled Release 93, 105-120 (Pubitemid 37421353)
    • (2003) Journal of Controlled Release , vol.93 , Issue.2 , pp. 105-120
    • Bulmus, V.1    Woodward, M.2    Lin, L.3    Murthy, N.4    Stayton, P.5    Hoffman, A.6
  • 133
    • 78649260473 scopus 로고    scopus 로고
    • Targeted delivery of siRNA to hepatocytes and hepatic stellate cells by bioconjugation
    • Zhu, L. and Mahato, R. I. (2010) Targeted delivery of siRNA to hepatocytes and hepatic stellate cells by bioconjugation Bioconjugate Chem. 21, 2119-2127
    • (2010) Bioconjugate Chem. , vol.21 , pp. 2119-2127
    • Zhu, L.1    Mahato, R.I.2
  • 134
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
    • DOI 10.1038/47513
    • Nakagawa, T., Zhu, H., Morishima, N., Li, E., Xu, J., Yankner, B. A., and Yuan, J. (2000) Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β Nature 403, 98-103 (Pubitemid 30038529)
    • (2000) Nature , vol.403 , Issue.6765 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3    Li, E.4    Xu, J.5    Yankner, B.A.6    Yuan, J.7
  • 135
    • 67649231388 scopus 로고    scopus 로고
    • Solid-phase synthesis of oligonucleotide conjugates useful for delivery and targeting of potential nucleic acid therapeutics
    • Lönnberg, H. (2009) Solid-phase synthesis of oligonucleotide conjugates useful for delivery and targeting of potential nucleic acid therapeutics Bioconjugate Chem. 20, 1065-1094
    • (2009) Bioconjugate Chem. , vol.20 , pp. 1065-1094
    • Lönnberg, H.1
  • 139
    • 41149179660 scopus 로고    scopus 로고
    • Efficient in vivo delivery of siRNA to the liver by conjugation of α-tocopherol
    • DOI 10.1038/mt.2008.14, PII MT200814
    • Nishina, K., Unno, T., Uno, Y., Kubodera, T., Kanouchi, T., Mizusawa, H., and Yokota, T. (2008) Efficient in vivo delivery of siRNA to the liver by conjugation of α-tocopherol Mol. Ther. 16, 734-740 (Pubitemid 351426175)
    • (2008) Molecular Therapy , vol.16 , Issue.4 , pp. 734-740
    • Nishina, K.1    Unno, T.2    Uno, Y.3    Kubodera, T.4    Kanouchi, T.5    Mizusawa, H.6    Yokota, T.7
  • 140
    • 33845216721 scopus 로고    scopus 로고
    • PEG conjugated VEGF siRNA for anti-angiogenic gene therapy
    • DOI 10.1016/j.jconrel.2006.05.023, PII S0168365906002458
    • Kim, S. H., Jeong, J. H., Lee, S. H., Kim, S. W., and Park, T. G. (2006) PEG conjugated VEGF siRNA for anti-angiogenic gene therapy J. Controlled Release 116, 123-129 (Pubitemid 44854271)
    • (2006) Journal of Controlled Release , vol.116 , Issue.2 SPEC. ISS. , pp. 123-129
    • Kim, S.H.1    Jeong, J.H.2    Lee, S.H.3    Kim, S.W.4    Park, T.G.5
  • 142
    • 13644254495 scopus 로고    scopus 로고
    • Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells
    • DOI 10.1021/ja044941d
    • Oishi, M., Nagasaki, Y., Itaka, K., Nishiyama, N., and Kataoka, K. (2005) Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells J. Am. Chem. Soc. 127, 1624-1625 (Pubitemid 40229133)
    • (2005) Journal of the American Chemical Society , vol.127 , Issue.6 , pp. 1624-1625
    • Oishi, M.1    Nagasaki, Y.2    Itaka, K.3    Nishiyama, N.4    Kataoka, K.5
  • 143
    • 38949186041 scopus 로고    scopus 로고
    • Site-specific delivery of oligonucleotides to hepatocytes after systemic administration
    • DOI 10.1021/bc070126m
    • Zhu, L., Ye, Z., Cheng, K., Miller, D. D., and Mahato, R. I. (2007) Site-specific delivery of oligonucleotides to hepatocytes after systemic administration Bioconjugate Chem. 19, 290-298 (Pubitemid 351213861)
    • (2008) Bioconjugate Chemistry , vol.19 , Issue.1 , pp. 290-298
    • Zhu, L.1    Ye, Z.2    Cheng, K.3    Miller, D.D.4    Mahato, R.I.5
  • 144
    • 41449109039 scopus 로고    scopus 로고
    • Breathing life into polycations: Functionalization with pH-responsive endosomolytic peptides and polyethylene glycol enables siRNA delivery
    • DOI 10.1021/ja710344v
    • Meyer, M., Philipp, A., Oskuee, R., Schmidt, C., and Wagner, E. (2008) Breathing life into polycations: functionalization with pH-responsive endosomolytic peptides and polyethylene glycol enables siRNA delivery J. Am. Chem. Soc. 130, 3272-3273 (Pubitemid 351456015)
    • (2008) Journal of the American Chemical Society , vol.130 , Issue.11 , pp. 3272-3273
    • Meyer, M.1    Philipp, A.2    Oskuee, R.3    Schmidt, C.4    Wagner, E.5
  • 145
    • 79551685593 scopus 로고    scopus 로고
    • Functional modification of amide-crosslinked oligoethylenimine for improved siRNA delivery
    • Philipp, A., Meyer, M., Zintchenko, A., and Wagner, E. (2011) Functional modification of amide-crosslinked oligoethylenimine for improved siRNA delivery Reactive Funct. Polymers 71, 288-293
    • (2011) Reactive Funct. Polymers , vol.71 , pp. 288-293
    • Philipp, A.1    Meyer, M.2    Zintchenko, A.3    Wagner, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.