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Angewandte Chemie - International Edition

Volumn 52, Issue 24, 2013, Pages 6218-6221

Acidic pH-responsive siRNA conjugate for reversible carrier stability and accelerated endosomal escape with reduced IFNα-associated immune response

(8) Takemoto, Hiroyasu a Miyata, Kanjiro a Hattori, Shota a Ishii, Takehiko a Suma, Tomoya a Uchida, Satoshi a Nishiyama, Nobuhiro b Kataoka, Kazunori a

a UNIVERSITY OF TOKYO (Japan)

b TOKYO INSTITUTE OF TECHNOLOGY (Japan)

Author keywords

conjugation; drug delivery; drug design; polymers; siRNA

Indexed keywords

ACIDIC PH VALUES; CANCEROUS CELLS; CARRIER STABILITY; CONJUGATION; DRUG DESIGN; ENDOSOMAL ESCAPES; IMMUNE RESPONSE; SIRNA;

DRUG DELIVERY; POLYMERS;

GENETIC ENGINEERING;

ACID; ALPHA INTERFERON; SMALL INTERFERING RNA;

ARTICLE; ENDOSOME; METABOLISM; PH;

ACIDS; ENDOSOMES; HYDROGEN-ION CONCENTRATION; INTERFERON-ALPHA; RNA, SMALL INTERFERING;

EID: 84878741878 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201300178 Document Type: Article

Times cited : (104)

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