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Volumn 19, Issue 2, 2011, Pages 381-385

Elimination pathways of systemically delivered siRNA

Author keywords

[No Author keywords available]

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; CHLORAMPHENICOL; CHOLESTEROL; DIGITOXIN; FLUORESCENT DYE; NAKED DNA; SMALL INTERFERING RNA;

EID: 79551617515     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2010.266     Document Type: Article
Times cited : (124)

References (11)
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  • 2
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    • Impact of tumorspecific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging
    • Bartlett, DW, Su, H, Hildebrandt, IJ, Weber, WA and Davis, ME (2007). Impact of tumorspecific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging. Proc Natl Acad Sci USA 104: 15549-15554.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15549-15554
    • Bartlett, D.W.1    Su, H.2    Hildebrandt, I.J.3    Weber, W.A.4    Davis, M.E.5
  • 3
    • 0037173610 scopus 로고    scopus 로고
    • Modulation of HIV-1 replication by RNA interference
    • Jacque, JM, Triques, K and Stevenson, M (2002). Modulation of HIV-1 replication by RNA interference. Nature 418: 435-438.
    • (2002) Nature , vol.418 , pp. 435-438
    • Jacque, J.M.1    Triques, K.2    Stevenson, M.3
  • 5
    • 9144223047 scopus 로고    scopus 로고
    • Short interfering RNA (siRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR-ABL1(+) leukemia cells
    • Ptasznik, A, Nakata, Y, Kalota, A, Emerson, SG and Gewirtz, AM (2004). Short interfering RNA (siRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR-ABL1(+) leukemia cells. Nat Med 10: 1187-1189.
    • (2004) Nat Med , vol.10 , pp. 1187-1189
    • Ptasznik, A.1    Nakata, Y.2    Kalota, A.3    Emerson, S.G.4    Gewirtz, A.M.5
  • 7
    • 9144247189 scopus 로고    scopus 로고
    • Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
    • Soutschek, J, Akinc, A, Bramlage, B, Charisse, K, Constien, R, Donoghue, M et al. (2004). Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 432: 173-178.
    • (2004) Nature , vol.432 , pp. 173-178
    • Soutschek, J.1    Akinc, A.2    Bramlage, B.3    Charisse, K.4    Constien, R.5    Donoghue, M.6
  • 8
    • 78649722174 scopus 로고    scopus 로고
    • Comprehensive analysis of sequence-specific stability of siRNA
    • epub ahead of print
    • Hong, J, Huang, Y, Li, J, Yi, F, Zheng, J, Huang, H et al. (2010). Comprehensive analysis of sequence-specific stability of siRNA. FASEB J (epub ahead of print).
    • (2010) FASEB J
    • Hong, J.1    Huang, Y.2    Li, J.3    Yi, F.4    Zheng, J.5    Huang, H.6
  • 10
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    • Radiolabeling small RNA with technetium-99m for visualizing cellular delivery and mouse biodistribution
    • Liu, N, Ding, H, Vanderheyden, JL, Zhu, Z and Zhang, Y (2007). Radiolabeling small RNA with technetium-99m for visualizing cellular delivery and mouse biodistribution. Nucl Med Biol 34: 399-404.
    • (2007) Nucl Med Biol , vol.34 , pp. 399-404
    • Liu, N.1    Ding, H.2    Vanderheyden, J.L.3    Zhu, Z.4    Zhang, Y.5
  • 11
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    • Biodistribution of 68Ga-labelled phosphodiester, phosphorothioate, and 2'-O-methyl phosphodiester oligonucleotides in normal rats
    • Lendvai, G, Velikyan, I, Bergström, M, Estrada, S, Laryea, D, Välilä, M et al. (2005). Biodistribution of 68Ga-labelled phosphodiester, phosphorothioate, and 2'-O-methyl phosphodiester oligonucleotides in normal rats. Eur J Pharm Sci 26: 26-38.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.