Increased interaction with insulin receptor substrate 1, a novel abnormality in insulin resistance and type 2 diabetes

Diabetes

Volumn 63, Issue 6, 2014, Pages 1933-1947

  Caruso, Michael ^a   Ma, Danjun ^a   Msallaty, Zaher ^b   Lewis, Monique ^a   Seyoum, Berhane ^b   Al Janabi, Wissam ^a   Diamond, Michael ^b,c   Abou Samra, Abdul B ^b,d   Højlund, Kurt ^e   Tagett, Rebecca ^f   Draghici, Sorin ^f   Zhang, Xiangmin ^a   Horowitz, Jeffrey F ^g   Yi, Zhengping ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

^d HAMAD MEDICAL CORPORATION   (Qatar)

^e ODENSE UNIVERSITY HOSPITAL   (Denmark)

^f Wayne State University   (United States)

^g UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; ALDEHYDE DEHYDROGENASE; ANKYRIN; ANNEXIN; APOLIPOPROTEIN A2; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALPAIN 1; CALSEQUESTRIN; CARNITINE ACETYLTRANSFERASE; CAVEOLIN 1; CD147 ANTIGEN; COFILIN 1; CULLIN; CYSTATIN B; CYTOCHROME C OXIDASE; CYTOCHROME C1; DIAZEPAM BINDING INHIBITOR; FUMARATE HYDRATASE; GLUCOSE; GLUCOSE REGULATED PROTEIN 78; GLUTAREDOXIN; GUANOSINE TRIPHOSPHATASE; HISTONE H2B; INSULIN RECEPTOR SUBSTRATE 1; KARYOPHERIN; PIG INSULIN; PROTEIN S6; STEFIN A; UBIQUINOL CYTOCHROME C REDUCTASE; UBIQUITIN PROTEIN LIGASE E3;

ACTIN FILAMENT; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOSKELETON; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HUMAN; HUMAN TISSUE; INSULIN BLOOD LEVEL; INSULIN INFUSION; INSULIN RESISTANCE; INSULIN RESPONSE; INSULIN SENSITIVITY; MALE; MUSCLE BIOPSY; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTEOMICS; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

BLOOD GLUCOSE; BODY MASS INDEX; DIABETES MELLITUS, TYPE 2; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GLUCOSE CLAMP TECHNIQUE; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; MUSCLE, SKELETAL; OBESITY; PROMOTER REGIONS, GENETIC; RISK FACTORS; RNA, MESSENGER; SIGNAL TRANSDUCTION; THINNESS;

EID: 84901325496     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-1872     Document Type: Article

References (50)

1. Rask-Madsen C, Kahn CR. Tissue-specific insulin signaling, metabolic syndrome, and cardiovascular disease. Arterioscler Thromb Vasc Biol 2012;32: 2052-2059
2. Abdul-Ghani MA, DeFronzo RA. Pathogenesis of insulin resistance in skeletal muscle. J Biomed Biotechnol 2010;2010:476279
3. Hojlund K, Beck-Nielsen H. Impaired glycogen synthase activity and mitochondrial dysfunction in skeletal muscle: markers or mediators in type 2 diabetes? Curr Diabetes Rev 2006;2:375-395
4. Lowell BB, Shulman GI. Mitochondrial dysfunction and type 2 diabetes. Science 2005;307:384-387
5. Mandavia C, Sowers Jr. Phosphoprotein phosphatase PP2A regulation of insulin receptor substrate 1 and insulin metabolic signaling. Cardiorenal Med 2012;2:308-313
6. Geetha T, Langlais P, Luo M, et al. Label-free proteomic identification of endogenous, insulin-stimulated interaction partners of insulin receptor substrate. J Am Soc Mass Spectrom 2011;22:457-466
7. Cusi K, Maezono K, Osman A, et al. Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle. J Clin Invest 2000;105:311-320
8. Grimmsmann T, Levin K, Meyer MM, Beck-Nielsen H, Klein HH. Delays in insulin signaling towards glucose disposal in human skeletal muscle. J Endocrinol 2002;172:645-651
9. Chen J, Capozza F, Wu A, et al. Regulation of insulin receptor substrate-1 expression levels by caveolin-1. J Cell Physiol 2008;217:281-289
10. Valverde AM, Mur C, Pons S, et al. Association of insulin receptor substrate 1 (IRS-1) y895 with Grb-2 mediates the insulin signaling involved in IRS-1- deficient brown adipocyte mitogenesis. Mol Cell Biol 2001;21:2269-2280 (Pubitemid 32222081)
11. Myers MG Jr, Mendez R, Shi P, Pierce JH, Rhoads R, White MF. The COOHterminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling. J Biol Chem 1998;273:26908-26914 (Pubitemid 28471711)
12. Copps KD, White MF. Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2. Diabetologia 2012;55:2565-2582
13. Ball LE, Berkaw MN, Buse MG. Identification of the major site of O-linked beta-N-acetylglucosamine modification in the C terminus of insulin receptor substrate-1. Mol Cell Proteomics 2006;5:313-323 (Pubitemid 43329309)
14. Saltiel AR, Pessin JE. Insulin signaling pathways in time and space. Trends Cell Biol 2002;12:65-71 (Pubitemid 34146521)
15. Wepf A, Glatter T, Schmidt A, Aebersold R, Gstaiger M. Quantitative interaction proteomics using mass spectrometry. Nat Methods 2009;6:203-205
16. Marcilla M, Albar JP. Quantitative proteomics: a strategic ally to map protein interaction networks. IUBMB Life 2013;65:9-16
17. Yi Z, Langlais P, De Filippis EA, et al. Global assessment of regulation of phosphorylation of insulin receptor substrate-1 by insulin in vivo in human muscle. Diabetes 2007;56:1508-1516 (Pubitemid 46842594)
18. Langlais P, Yi Z, Finlayson J, et al. Global IRS-1 phosphorylation analysis in insulin resistance. Diabetologia 2011;54:2878-2889
19. Chen XW, Wang H, Bajaj K, et al. SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion. eLife 2013;2:e00444
20. Cox J, Mann M. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat Biotechnol 2008;26:1367-1372
21. Donato M, Xu Z, Tomoiaga A, et al. Analysis and correction of crosstalk effects in pathway analysis. Genome Res 2013;23:1885-1893
22. Thomas S, Bonchev D. A survey of current software for network analysis in molecular biology. Hum Genomics 2010;4:353-360
23. Kanehisa M, Goto S. KEGG: Kyoto Encyclopedia of Genes And Genomes. Nucleic Acids Res 2000;28:27-30 (Pubitemid 30047706)
24. Croft D, O'Kelly G, Wu G, et al. Reactome: a database of reactions, pathways and biological processes. Nucleic Acids Res 2011;39(Database issue):D691- D697
25. Gygi SP, Rochon Y, Franza BR, Aebersold R. Correlation between protein and mRNA abundance in yeast. Mol Cell Biol 1999;19:1720-1730 (Pubitemid 29098230)
26. Ni YG, Wang N, Cao DJ, et al. FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases. Proc Natl Acad Sci U S A 2007;104:20517-20522
27. Kowluru A, Matti A. Hyperactivation of protein phosphatase 2A in models of glucolipotoxicity and diabetes: potential mechanisms and functional consequences. Biochem Pharmacol 2012;84:591-597
28. Jelenik T, Roden M. Mitochondrial plasticity in obesity and diabetes mellitus. Antioxid Redox Signal 2013;19:258-268
29. Newgard CB. Interplay between lipids and branched-chain amino acids in development of insulin resistance. Cell Metab 2012;15:606-614
30. Hwang H, Bowen BP, Lefort N, et al. Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes. Diabetes 2010;59:33-42
31. Hanke S, Mann M. The phosphotyrosine interactome of the insulin receptor family and its substrates IRS-1 and IRS-2. Mol Cell Proteomics 2009;8:519-534
32. Odegaard JI, Chawla A. Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis. Science 2013;339:172-177
33. Dali-Youcef N, Mecili M, Ricci R, Andrès E. Metabolic inflammation: connecting obesity and insulin resistance. Ann Med 2013;45:242-253
34. Garrean S, Gao XP, Brovkovych V, et al. Caveolin-1 regulates NF-kappaB activation and lung inflammatory response to sepsis induced by lipopolysaccharide. J Immunol 2006;177:4853-4860 (Pubitemid 44469821)
35. Kim SY. Transglutaminase 2 in inflammation. Front Biosci 2006;11:3026- 3035
36. Reddy VS, Prabhu SD, Mummidi S, et al. Interleukin-18 induces EMMPRIN expression in primary cardiomyocytes via JNK/Sp1 signaling and MMP-9 in part via EMMPRIN and through AP-1 and NF-kappaB activation. Am J Physiol Heart Circ Physiol 2010;299:H1242-H1254
37. Shi J, Luo L, Eash J, Ibebunjo C, Glass DJ. The SCF-Fbxo40 complex induces IRS1 ubiquitination in skeletal muscle, limiting IGF1 signaling. Dev Cell 2011;21:835-847
38. Rui L, Yuan M, Frantz D, Shoelson S, White MF. SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2. J Biol Chem 2002;277:42394-42398 (Pubitemid 35257562)
39. Wang X, Hu Z, Hu J, Du J, Mitch WE. Insulin resistance accelerates muscle protein degradation: activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling. Endocrinology 2006;147:4160-4168 (Pubitemid 44268367)
40. Sharma AK, Bharti S, Ojha S, et al. Up-regulation of PPARg, heat shock protein-27 and -72 by naringin attenuates insulin resistance, β-cell dysfunction, hepatic steatosis and kidney damage in a rat model of type 2 diabetes. Br J Nutr 2011;106:1713-1723
41. Ye R, Jung DY, Jun JY, et al. Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance. Diabetes 2010;59:6-16
42. Gottlieb PD, Pierce SA, Sims RJ, et al. Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis. Nat Genet 2002;31:25-32
43. Proud CG, Denton RM. Molecular mechanisms for the control of translation by insulin. Biochem J 1997;328:329-341 (Pubitemid 27515570)
44. Jäkel S, Görlich D. Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells. EMBO J 1998;17: 4491-4502 (Pubitemid 28362637)
45. Halvatsiotis P, Short KR, Bigelow M, Nair KS. Synthesis rate of muscle proteins, muscle functions, and amino acid kinetics in type 2 diabetes. Diabetes 2002;51:2395-2404 (Pubitemid 34827387)
46. Hoffman NJ, Elmendorf JS. Signaling, cytoskeletal and membrane mechanisms regulating GLUT4 exocytosis. Trends Endocrinol Metab 2011;22:110-116
47. Stöckli J, Fazakerley DJ, James DE. GLUT4 exocytosis. J Cell Sci 2011;124: 4147-4159
48. Langlais P, Dillon JL, Mengos A, et al. Identification of a role for CLASP2 in insulin action. J Biol Chem 2012;287:39245-39253
49. Semiz S, Park JG, Nicoloro SM, et al. Conventional kinesin KIF5B mediates insulin-stimulated GLUT4 movements on microtubules. EMBO J 2003;22:2387- 2399 (Pubitemid 36604978)
50. Rodgers BD, Levine MA, Bernier M, Montrose-Rafizadeh C. Insulin regulation of a novel WD-40 repeat protein in adipocytes. J Endocrinol 2001;168:325- 332 (Pubitemid 32181609)