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Volumn 17, Issue 15, 1998, Pages 4491-4502

Importin β, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells

Author keywords

Importin ; Nuclear transport; RanBP7; Ribosomes; Transportin

Indexed keywords

CARRIER PROTEIN; KARYOPHERIN; RIBOSOME PROTEIN;

EID: 0040251482     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.15.4491     Document Type: Article
Times cited : (441)

References (74)
  • 1
    • 0028217405 scopus 로고
    • Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope
    • Adam, E.J.H. and Adam, S.A. (1994) Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope. J. Cell Biol., 125, 547-555.
    • (1994) J. Cell Biol. , vol.125 , pp. 547-555
    • Adam, E.J.H.1    Adam, S.A.2
  • 2
    • 0025083331 scopus 로고
    • Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors
    • Adam, S.A., Sterne Marr, R. and Gerace, L. (1990) Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors. J. Cell Biol., 111, 807-816.
    • (1990) J. Cell Biol. , vol.111 , pp. 807-816
    • Adam, S.A.1    Sterne Marr, R.2    Gerace, L.3
  • 3
    • 0032510462 scopus 로고    scopus 로고
    • Identification of a nuclear export receptor for tRNA
    • Arts, G.-J., Fornerod, M. and Mattaj, I.W. (1998) Identification of a nuclear export receptor for tRNA. Curr. Biol., 8, 305-314.
    • (1998) Curr. Biol. , vol.8 , pp. 305-314
    • Arts, G.-J.1    Fornerod, M.2    Mattaj, I.W.3
  • 4
    • 0028977973 scopus 로고
    • RNAI encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae
    • Becker, J., Melchior, F., Gerke, V., Bischoff, F.R., Ponstingl, H. and Wittinghofer, A. (1995) RNAI encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae. J. Biol. Chem., 270, 11860-11865.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11860-11865
    • Becker, J.1    Melchior, F.2    Gerke, V.3    Bischoff, F.R.4    Ponstingl, H.5    Wittinghofer, A.6
  • 5
    • 0345647103 scopus 로고    scopus 로고
    • RanBP1 is crucial for the the release of RanGTP from importin β-related nuclear transport factors
    • Bischoff, F.R. and Görlich, D. (1997) RanBP1 is crucial for the the release of RanGTP from importin β-related nuclear transport factors. FEBS Lett., 419, 249-254.
    • (1997) FEBS Lett. , vol.419 , pp. 249-254
    • Bischoff, F.R.1    Görlich, D.2
  • 6
    • 0026419320 scopus 로고
    • Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1
    • Bischoff, F.R. and Ponstingl, H. (1991) Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1. Nature, 354, 80-82.
    • (1991) Nature , vol.354 , pp. 80-82
    • Bischoff, F.R.1    Ponstingl, H.2
  • 8
    • 0028934834 scopus 로고
    • Human RanGTPase activating protein RanGAP1 is a homolog of yeast RNA1p involved in messenger RNA processing and transport
    • Bischoff, F.R., Krebber, H., Kempf, T., Hermes, I. and Ponstingl, H. (1995) Human RanGTPase activating protein RanGAP1 is a homolog of yeast RNA1p involved in messenger RNA processing and transport. Proc. Natl Acad. Sci. USA, 92, 1749-1753.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 1749-1753
    • Bischoff, F.R.1    Krebber, H.2    Kempf, T.3    Hermes, I.4    Ponstingl, H.5
  • 9
    • 0002009016 scopus 로고
    • Protein migration and accumulation in nuclei
    • Busch, H. (ed.), Academic Press, New York
    • Bonner, W.M. (1978) Protein migration and accumulation in nuclei. In Busch, H. (ed.), The Cell Nucleus. Academic Press, New York, Vol. 6, part C, pp. 97-148.
    • (1978) The Cell Nucleus , vol.6 , Issue.PART C , pp. 97-148
    • Bonner, W.M.1
  • 10
    • 0025269856 scopus 로고
    • Facilitated nuclear transport of histone H1 and other small nucleophilic proteins
    • Breeuwer, M. and Goldfarb, D. (1990) Facilitated nuclear transport of histone H1 and other small nucleophilic proteins. Cell, 60, 999-1008.
    • (1990) Cell , vol.60 , pp. 999-1008
    • Breeuwer, M.1    Goldfarb, D.2
  • 11
    • 0030910804 scopus 로고    scopus 로고
    • Functional domains in nuclear import factor p97 for binding the nuclear localization sequence receptor and the nuclear pore
    • Chi, N.C. and Adam, S.A. (1997) Functional domains in nuclear import factor p97 for binding the nuclear localization sequence receptor and the nuclear pore. Mol. Biol. Cell, 8, 945-956.
    • (1997) Mol. Biol. Cell , vol.8 , pp. 945-956
    • Chi, N.C.1    Adam, S.A.2
  • 12
    • 0029115837 scopus 로고
    • Sequence and characterization of cytoplasmic nuclear import factor p97
    • Chi, N.C., Adam, E.J.H. and Adam, S.A. (1995) Sequence and characterization of cytoplasmic nuclear import factor p97. J. Cell Biol., 130, 265-274.
    • (1995) J. Cell Biol. , vol.130 , pp. 265-274
    • Chi, N.C.1    Adam, E.J.H.2    Adam, S.A.3
  • 13
    • 0029847386 scopus 로고    scopus 로고
    • RanBP1 stabilises the interaction of Ran with p97 in nuclear protein import
    • Chi, N.C., Adam, E.J.H., Visser, G.D. and Adam, S.A. (1996) RanBP1 stabilises the interaction of Ran with p97 in nuclear protein import. J. Cell Biol., 135, 559-569.
    • (1996) J. Cell Biol. , vol.135 , pp. 559-569
    • Chi, N.C.1    Adam, E.J.H.2    Visser, G.D.3    Adam, S.A.4
  • 14
    • 0030793194 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport of macromolecules
    • Corbett, A.H. and Silver, P.A. (1997) Nucleocytoplasmic transport of macromolecules. Microbiol. Mol. Biol. Rev., 61, 193-211.
    • (1997) Microbiol. Mol. Biol. Rev. , vol.61 , pp. 193-211
    • Corbett, A.H.1    Silver, P.A.2
  • 15
    • 0027732054 scopus 로고
    • Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4
    • Coutavas, E., Ren, M., Oppenheim, J.D., D'Eustachio, P. and Rush, M.G. (1993) Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4. Nature, 366, 585-587.
    • (1993) Nature , vol.366 , pp. 585-587
    • Coutavas, E.1    Ren, M.2    Oppenheim, J.D.3    D'Eustachio, P.4    Rush, M.G.5
  • 16
    • 1842375738 scopus 로고    scopus 로고
    • Ran binding protein 5 (RanBP5) is related to the nuclear transport factor importin beta but interacts differently with RanBP1
    • Deane, R., Schafer, W., Zimmermann, H.P., Mueller, L., Görlich, D., Prehn, S., Ponstingl, H. and Bischoff, F.R. (1997) Ran binding protein 5 (RanBP5) is related to the nuclear transport factor importin beta but interacts differently with RanBP1. Mol. Cell. Biol., 17, 5087-5096.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5087-5096
    • Deane, R.1    Schafer, W.2    Zimmermann, H.P.3    Mueller, L.4    Görlich, D.5    Prehn, S.6    Ponstingl, H.7    Bischoff, F.R.8
  • 17
    • 0021717131 scopus 로고
    • Movement of karyophilic protein through the nuclear pores of oocytes
    • Feldherr, C.M., Kallenbach, E. and Schultz, N. (1984) Movement of karyophilic protein through the nuclear pores of oocytes. J. Cell Biol., 99, 2216-2222.
    • (1984) J. Cell Biol. , vol.99 , pp. 2216-2222
    • Feldherr, C.M.1    Kallenbach, E.2    Schultz, N.3
  • 18
    • 0030851465 scopus 로고    scopus 로고
    • Disassembly of RanGTP-karyopherin beta complex, an intermediate in nuclear protein import
    • Floer, M. Blobel, G. and Rexach, M. (1997) Disassembly of RanGTP-karyopherin beta complex, an intermediate in nuclear protein import. J. Biol. Chem., 272, 19538-19546.
    • (1997) J. Biol. Chem. , vol.272 , pp. 19538-19546
    • Floer, M.1    Blobel, G.2    Rexach, M.3
  • 19
    • 0031053791 scopus 로고    scopus 로고
    • The human homologue of yeast Crm1 is in a dynamic subcomplex with Can/ Nup214 and a novel nuclear pore component Nup88
    • Fornerod, M. Vandeursen, J., Vanbaal, S., Reynolds, A., Davis, D., Murti, K.G., Fransen, J. and Grosveld, G. (1997a) The human homologue of yeast Crm1 is in a dynamic subcomplex with Can/ Nup214 and a novel nuclear pore component Nup88. EMBO J., 16, 807-816.
    • (1997) EMBO J. , vol.16 , pp. 807-816
    • Fornerod, M.1    Vandeursen, J.2    Vanbaal, S.3    Reynolds, A.4    Davis, D.5    Murti, K.G.6    Fransen, J.7    Grosveld, G.8
  • 20
    • 0030924190 scopus 로고    scopus 로고
    • Crm1 is an export receptor for leucine rich nuclear export signals
    • Fornerod, M., Ohno, M., Yoshida, M. and Mattaj, I.W. (1997b) Crm1 is an export receptor for leucine rich nuclear export signals. Cell, 90, 1051-1060.
    • (1997) Cell , vol.90 , pp. 1051-1060
    • Fornerod, M.1    Ohno, M.2    Yoshida, M.3    Mattaj, I.W.4
  • 21
    • 0030971249 scopus 로고    scopus 로고
    • Nuclear import of hnRNP A1 is mediated by a novel cellular cofactor related to karyopherin-β
    • Fridell, R.A., Truant, R., Thorne, L., Benson, R.E. and Cullen, B.R. (1997) Nuclear import of hnRNP A1 is mediated by a novel cellular cofactor related to karyopherin-β. J. Cell Sci., 110, 1325-1331.
    • (1997) J. Cell Sci. , vol.110 , pp. 1325-1331
    • Fridell, R.A.1    Truant, R.2    Thorne, L.3    Benson, R.E.4    Cullen, B.R.5
  • 22
    • 0040182590 scopus 로고    scopus 로고
    • Nuclear protein import
    • Görlich, D. (1997) Nuclear protein import. Curr. Opin. Cell Biol., 9, 412-419.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 412-419
    • Görlich, D.1
  • 23
    • 0029984570 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport
    • Görlich, D. and Mattaj, I.W. (1996) Nucleocytoplasmic transport. Science, 271, 1513-1518.
    • (1996) Science , vol.271 , pp. 1513-1518
    • Görlich, D.1    Mattaj, I.W.2
  • 24
    • 0027937653 scopus 로고
    • Isolation of a protein that is essential for the first step of nuclear protein import
    • Görlich, D., Prehn, S., Laskey, R.A. and Hartmann, E. (1994) Isolation of a protein that is essential for the first step of nuclear protein import. Cell, 79, 767-778.
    • (1994) Cell , vol.79 , pp. 767-778
    • Görlich, D.1    Prehn, S.2    Laskey, R.A.3    Hartmann, E.4
  • 25
    • 0029278621 scopus 로고
    • Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope
    • Görlich, D., Kostka, S., Kraft, R., Dingwall, C., Laskey, R.A., Hartmann, E. and Prehn, S. (1995a) Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope. Curr. Biol., 5, 383-392.
    • (1995) Curr. Biol. , vol.5 , pp. 383-392
    • Görlich, D.1    Kostka, S.2    Kraft, R.3    Dingwall, C.4    Laskey, R.A.5    Hartmann, E.6    Prehn, S.7
  • 26
    • 0029059548 scopus 로고
    • Distinct functions for the two importin subunits in nuclear protein import
    • Görlich, D., Vogel, F., Mills, A.D., Hartmann, E. and Laskey, R.A. (1995b) Distinct functions for the two importin subunits in nuclear protein import. Nature, 377, 246-248.
    • (1995) Nature , vol.377 , pp. 246-248
    • Görlich, D.1    Vogel, F.2    Mills, A.D.3    Hartmann, E.4    Laskey, R.A.5
  • 27
    • 0029921174 scopus 로고    scopus 로고
    • A 41 amino acid motif in importin alpha confers binding to importin beta and hence transit into the nucleus
    • Görlich, D., Henklein, P., Laskey, R A. and Hartmann, E. (1996a) A 41 amino acid motif in importin alpha confers binding to importin beta and hence transit into the nucleus. EMBO J., 15, 1810-1817.
    • (1996) EMBO J. , vol.15 , pp. 1810-1817
    • Görlich, D.1    Henklein, P.2    Laskey, R.A.3    Hartmann, E.4
  • 28
    • 0029853631 scopus 로고    scopus 로고
    • Identification of different roles for RanGDP and RanGTP in nuclear protein import
    • Görlich, D., Panté, N., Kutay, U., Aebi, U. and Bischoff, F.R. (1996b) Identification of different roles for RanGDP and RanGTP in nuclear protein import. EMBO J., 15, 5584-5594.
    • (1996) EMBO J. , vol.15 , pp. 5584-5594
    • Görlich, D.1    Panté, N.2    Kutay, U.3    Aebi, U.4    Bischoff, F.R.5
  • 31
    • 0031578895 scopus 로고    scopus 로고
    • Interactions between HIV Rev. and nuclear import and export factors: The Rev. nuclear localisation signal mediates specific binding to human importin-beta
    • Henderson, B.R. and Percipalle, P. (1997) Interactions between HIV Rev. and nuclear import and export factors: the Rev. nuclear localisation signal mediates specific binding to human importin-beta. J. Mol. Biol., 274, 693-707.
    • (1997) J. Mol. Biol. , vol.274 , pp. 693-707
    • Henderson, B.R.1    Percipalle, P.2
  • 32
    • 0025375307 scopus 로고
    • The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus
    • Hopper, A., Traglia, H.M. and Dunst, R.W. (1990) The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus. J. Cell Biol., 111, 309-321.
    • (1990) J. Cell Biol. , vol.111 , pp. 309-321
    • Hopper, A.1    Traglia, H.M.2    Dunst, R.W.3
  • 33
    • 0028970112 scopus 로고
    • A karyophilic protein forms a stable complex with cytoplasmic components prior to nuclear pore binding
    • Imamoto, N., Tachibana, T., Matsubae, M. and Yoneda, Y. (1995a) A karyophilic protein forms a stable complex with cytoplasmic components prior to nuclear pore binding. J. Biol. Chem., 270, 8559-8565.
    • (1995) J. Biol. Chem. , vol.270 , pp. 8559-8565
    • Imamoto, N.1    Tachibana, T.2    Matsubae, M.3    Yoneda, Y.4
  • 34
    • 0029093824 scopus 로고
    • In vivo evidence for involvement of a 58 kDa component of nuclear pore targeting complex in nuclear protein import
    • Imamoto, N., Shimamoto, T., Takao, T., Tachibana, T., Kose, S., Matsubae, M., Sekimoto, T., Shimonishi, Y. and Yoneda, Y. (1995b) In vivo evidence for involvement of a 58 kDa component of nuclear pore targeting complex in nuclear protein import. EMBO J., 14, 3617-3626.
    • (1995) EMBO J. , vol.14 , pp. 3617-3626
    • Imamoto, N.1    Shimamoto, T.2    Takao, T.3    Tachibana, T.4    Kose, S.5    Matsubae, M.6    Sekimoto, T.7    Shimonishi, Y.8    Yoneda, Y.9
  • 35
    • 0031954020 scopus 로고    scopus 로고
    • Transport of macromolecules between the nucleus and the cytoplasm
    • Izaurralde, E. and Adam, S.A. (1998) Transport of macromolecules between the nucleus and the cytoplasm. RNA, 4, 351-364.
    • (1998) RNA , vol.4 , pp. 351-364
    • Izaurralde, E.1    Adam, S.A.2
  • 36
    • 0030856315 scopus 로고    scopus 로고
    • The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus
    • Izaurralde, E., Kutay, U., von Kobbe, C., Mattaj, I.W. and Görlich, D. (1997) The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus. EMBO J., 16, 6535-6547.
    • (1997) EMBO J. , vol.16 , pp. 6535-6547
    • Izaurralde, E.1    Kutay, U.2    Von Kobbe, C.3    Mattaj, I.W.4    Görlich, D.5
  • 37
    • 0021269089 scopus 로고
    • Sequence requirements for nuclear location of simian virus 40 large T antigen
    • Kalderon, D., Richardson, W.D., Markham, A.F. and Smith, A.E. (1984) Sequence requirements for nuclear location of simian virus 40 large T antigen. Nature, 311, 33-38.
    • (1984) Nature , vol.311 , pp. 33-38
    • Kalderon, D.1    Richardson, W.D.2    Markham, A.F.3    Smith, A.E.4
  • 38
    • 0030960586 scopus 로고    scopus 로고
    • Dominant-negative mutants of importin-β block multiple pathways of import and export through the nuclear pore complex
    • Kutay, U., Izaurralde, E., Bischoff, F.R., Mattaj, I.W. and Görlich, D. (1997a) Dominant-negative mutants of importin-β block multiple pathways of import and export through the nuclear pore complex. EMBO J., 16, 1153-1163.
    • (1997) EMBO J. , vol.16 , pp. 1153-1163
    • Kutay, U.1    Izaurralde, E.2    Bischoff, F.R.3    Mattaj, I.W.4    Görlich, D.5
  • 39
    • 0342276108 scopus 로고    scopus 로고
    • Export of importin α from the nucleus is mediated by a specific nuclear transport factor
    • Kutay, U., Bischoff, F.R., Kostka, S., Kraft, R. and Görlich, D. (1997b) Export of importin α from the nucleus is mediated by a specific nuclear transport factor. Cell, 90, 1061-1071.
    • (1997) Cell , vol.90 , pp. 1061-1071
    • Kutay, U.1    Bischoff, F.R.2    Kostka, S.3    Kraft, R.4    Görlich, D.5
  • 41
    • 0031016658 scopus 로고    scopus 로고
    • Ran-binding protein 1 (RanBP1) forms a ternary complex with Ran and karyopherin beta and reduces GTPase-activating protein (RanGAP) inhibition by karyopherin beta
    • Lounsbury, K.M. and Macara, I.G. (1997) Ran-binding protein 1 (RanBP1) forms a ternary complex with Ran and karyopherin beta and reduces GTPase-activating protein (RanGAP) inhibition by karyopherin beta. J. Biol. Chem., 272, 551-555.
    • (1997) J. Biol. Chem. , vol.272 , pp. 551-555
    • Lounsbury, K.M.1    Macara, I.G.2
  • 42
    • 0030932134 scopus 로고    scopus 로고
    • A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2
    • Mahajan, R., Delphin, C., Guan, T., Gerace, L. and Melchior, F. (1997) A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2. Cell, 88, 97-107.
    • (1997) Cell , vol.88 , pp. 97-107
    • Mahajan, R.1    Delphin, C.2    Guan, T.3    Gerace, L.4    Melchior, F.5
  • 43
    • 0030221192 scopus 로고    scopus 로고
    • Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids
    • Makkerh, J.PS., Dingwall, C. and Laskey, R.A. (1996) Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids. Curr. Biol., 6, 1025-1027.
    • (1996) Curr. Biol. , vol.6 , pp. 1025-1027
    • Makkerh, J.P.S.1    Dingwall, C.2    Laskey, R.A.3
  • 44
    • 0031707505 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport: The soluble phase
    • Mattaj, I.W. and Englmeier, L. (1998) Nucleocytoplasmic transport: the soluble phase. Annu. Rev. Biochem., 67, 265-306.
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 265-306
    • Mattaj, I.W.1    Englmeier, L.2
  • 45
    • 0030455748 scopus 로고    scopus 로고
    • A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein between cytosol and nuclear pore complex
    • Matunis, M.J., Coutavas, E. and Blobel, G. (1996) A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein between cytosol and nuclear pore complex. J. Cell Biol., 135, 1457-1470.
    • (1996) J. Cell Biol. , vol.135 , pp. 1457-1470
    • Matunis, M.J.1    Coutavas, E.2    Blobel, G.3
  • 46
    • 0027714921 scopus 로고
    • Inhibition of nuclear protein import by nonhydrolyzable analogs of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor
    • Melchior, F., Paschal, B., Evans, E. and Gerace, L. (1993a) Inhibition of nuclear protein import by nonhydrolyzable analogs of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor. J. Cell Biol., 123, 1649-1659.
    • (1993) J. Cell Biol. , vol.123 , pp. 1649-1659
    • Melchior, F.1    Paschal, B.2    Evans, E.3    Gerace, L.4
  • 47
    • 0027154650 scopus 로고
    • A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: Purification. biochemical characterization, and identification of a leucine-rich repeat motif
    • Melchior, F., Weber, K. and Gerke, V. (1993b) A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification. biochemical characterization, and identification of a leucine-rich repeat motif. Mol. Biol. Cell, 4, 569-581.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 569-581
    • Melchior, F.1    Weber, K.2    Gerke, V.3
  • 48
    • 0029055194 scopus 로고
    • The nucleolus: An organelle formed by the act of building a ribosome
    • Melese, T. and Xue, Z. (1995) The nucleolus: an organelle formed by the act of building a ribosome. Curr. Opin. Cell Biol., 7, 319-324.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 319-324
    • Melese, T.1    Xue, Z.2
  • 49
    • 0028845313 scopus 로고
    • A nuclear export signal in hnRNP A1: A signal-mediated, temperature-dependent nuclear protein export pathway
    • Michael, W.M., Choi, M. and Dreyfuss, G. (1995) A nuclear export signal in hnRNP A1: a signal-mediated, temperature-dependent nuclear protein export pathway. Cell, 83, 415-422.
    • (1995) Cell , vol.83 , pp. 415-422
    • Michael, W.M.1    Choi, M.2    Dreyfuss, G.3
  • 50
    • 0027376308 scopus 로고
    • The GTP-binding protein Ran/TC4 is required for protein import into the nucleus
    • Moore, M.S. and Blobel, G. (1993) The GTP-binding protein Ran/TC4 is required for protein import into the nucleus. Nature, 365, 661-663.
    • (1993) Nature , vol.365 , pp. 661-663
    • Moore, M.S.1    Blobel, G.2
  • 51
    • 0028983494 scopus 로고
    • Mammalian karyopherin a1b and a2b heterodimers: A1 or a2 subunit binds nuclear localization sequence and b subunit interacts with peptide repeat containing nucleoporins
    • Moroianu, J., Hijikata, M., Blobel, G. and Radu, A. (1995) Mammalian karyopherin a1b and a2b heterodimers: a1 or a2 subunit binds nuclear localization sequence and b subunit interacts with peptide repeat containing nucleoporins. Proc. Natl Acad. Sci. USA, 92, 6532-6536.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 6532-6536
    • Moroianu, J.1    Hijikata, M.2    Blobel, G.3    Radu, A.4
  • 52
    • 0030964105 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport: Signals, mechanisms and regulation
    • Nigg, E.A. (1997) Nucleocytoplasmic transport: signals, mechanisms and regulation. Nature, 386, 779-787.
    • (1997) Nature , vol.386 , pp. 779-787
    • Nigg, E.A.1
  • 53
    • 0024445582 scopus 로고
    • The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA
    • Ohtsubo, M., Okazaki, H. and Nishimoto, T. (1989) The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA. J. Cell Biol., 109, 1389-1397.
    • (1989) J. Cell Biol. , vol.109 , pp. 1389-1397
    • Ohtsubo, M.1    Okazaki, H.2    Nishimoto, T.3
  • 55
    • 0028950991 scopus 로고
    • Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins
    • Radu, A., Blobel, G. and Moore, M.S. (1995) Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. Proc. Natl Acad. Sci. USA, 92, 1769-1773.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 1769-1773
    • Radu, A.1    Blobel, G.2    Moore, M.S.3
  • 56
    • 0028834428 scopus 로고
    • Protein import into nuclei: Association and dissociation reactions involving transport substrate, transport factors, and nucleoporins
    • Rexach, M. and Blobel, G. (1995) Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins. Cell, 83, 683-692.
    • (1995) Cell , vol.83 , pp. 683-692
    • Rexach, M.1    Blobel, G.2
  • 57
    • 0029738481 scopus 로고    scopus 로고
    • A nuclear export signal is essential for the cytosolic localisation of the Ran binding protein. RanBP1
    • Richards, S.A., Lounsbury, K.M., Carey, K.L. and Macara, I.G. (1996) A nuclear export signal is essential for the cytosolic localisation of the Ran binding protein. RanBP1. J. Cell Biol., 134, 1157-1168.
    • (1996) J. Cell Biol. , vol.134 , pp. 1157-1168
    • Richards, S.A.1    Lounsbury, K.M.2    Carey, K.L.3    Macara, I.G.4
  • 58
    • 0026078249 scopus 로고
    • Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence
    • Robbins, J., Dilworth, S.M., Laskey, R.A. and Dingwall, C. (1991) Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. Cell, 64, 615-623.
    • (1991) Cell , vol.64 , pp. 615-623
    • Robbins, J.1    Dilworth, S.M.2    Laskey, R.A.3    Dingwall, C.4
  • 59
    • 0030722506 scopus 로고    scopus 로고
    • A distinct nuclear import pathway used by ribosomal proteins
    • Rout, M.P., Blobel, G. and Aitchison, J.D. (1997) A distinct nuclear import pathway used by ribosomal proteins. Cell, 89, 715-725.
    • (1997) Cell , vol.89 , pp. 715-725
    • Rout, M.P.1    Blobel, G.2    Aitchison, J.D.3
  • 60
    • 0031054690 scopus 로고    scopus 로고
    • Different domains cooperate to target the human ribosomal L7a protein to the nucleus and to the nucleoli
    • Russo, G., Ricciardelli, G. and Pietropaolo, C. (1997) Different domains cooperate to target the human ribosomal L7a protein to the nucleus and to the nucleoli. J. Biol. Chem., 272, 5229-5235.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5229-5235
    • Russo, G.1    Ricciardelli, G.2    Pietropaolo, C.3
  • 61
    • 0025832393 scopus 로고
    • Identification and functional analysis of the nuclear localization signals of ribosomal protein L25 from Saccharomyces cerevisiae
    • Schaap, P.J., van't Riet, J., Woldringh, C.L. and Raue, H.A. (1991) Identification and functional analysis of the nuclear localization signals of ribosomal protein L25 from Saccharomyces cerevisiae. J. Mol. Biol., 221, 225-237.
    • (1991) J. Mol. Biol. , vol.221 , pp. 225-237
    • Schaap, P.J.1    Van't Riet, J.2    Woldringh, C.L.3    Raue, H.A.4
  • 63
    • 0028784164 scopus 로고
    • Mutants in a yeast Ran binding protein are defective in nuclear transport
    • Schlenstedt, G., Wong, D.H., Koepp, D.M. and Silver, P.A. (1995) Mutants in a yeast Ran binding protein are defective in nuclear transport. EMBO J., 14, 5367-5378.
    • (1995) EMBO J. , vol.14 , pp. 5367-5378
    • Schlenstedt, G.1    Wong, D.H.2    Koepp, D.M.3    Silver, P.A.4
  • 65
    • 0028784029 scopus 로고
    • Nuclear and nucleolar targeting of human ribosomal protein S6
    • Schmidt, C., Lipsius, E. and Kruppa, J. (1995) Nuclear and nucleolar targeting of human ribosomal protein S6. Mol. Biol. Cell, 6, 1875-1885.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 1875-1885
    • Schmidt, C.1    Lipsius, E.2    Kruppa, J.3
  • 66
    • 0028930155 scopus 로고
    • A nuclear localization domain in the hnRNP A1 protein
    • Siomi, H. and Dreyfuss, G. (1995) A nuclear localization domain in the hnRNP A1 protein. J. Cell Biol., 129, 551-560.
    • (1995) J. Cell Biol. , vol.129 , pp. 551-560
    • Siomi, H.1    Dreyfuss, G.2
  • 67
    • 0030772652 scopus 로고    scopus 로고
    • Transportin-mediated nuclear import of heterogenous RNP proteins
    • Siomi, M.C., Eder, P.S., Kataoka, N., Wan, L., Liu, Q. and Dreyfuss, G. (1997) Transportin-mediated nuclear import of heterogenous RNP proteins. J. Cell Biol. 138, 1181-1192.
    • (1997) J. Cell Biol. , vol.138 , pp. 1181-1192
    • Siomi, M.C.1    Eder, P.S.2    Kataoka, N.3    Wan, L.4    Liu, Q.5    Dreyfuss, G.6
  • 69
    • 0030886673 scopus 로고    scopus 로고
    • Nuclear export receptors: From importin to exportin
    • Ullmann, K.S., Powers, M.A. and Forbes, D.J. (1997) Nuclear export receptors: from importin to exportin. Cell, 90, 967-970.
    • (1997) Cell , vol.90 , pp. 967-970
    • Ullmann, K.S.1    Powers, M.A.2    Forbes, D.J.3
  • 70
    • 0020994721 scopus 로고
    • Preparation of microsomal membranes for cotranslational protein translocation
    • Walter, P. and Blobel, G. (1983) Preparation of microsomal membranes for cotranslational protein translocation. Methods Enzymol., 96, 84-93.
    • (1983) Methods Enzymol. , vol.96 , pp. 84-93
    • Walter, P.1    Blobel, G.2
  • 71
    • 0028963968 scopus 로고
    • Nucleo-cytoplasmic distribution of human hnRNP proteins: A search for the targeting domains of hnRNP A1
    • Weighardt, F., Biamonti, G. and Riva, S. (1995) Nucleo-cytoplasmic distribution of human hnRNP proteins: a search for the targeting domains of hnRNP A1. J. Cell Sci., 108, 545-555.
    • (1995) J. Cell Sci. , vol.108 , pp. 545-555
    • Weighardt, F.1    Biamonti, G.2    Riva, S.3
  • 72
    • 0030010107 scopus 로고    scopus 로고
    • The conserved amino terminal domain of hSRP1α is essential for nuclear protein import
    • Weis, K., Ryder, U. and Lamond, A.I. (1996) The conserved amino terminal domain of hSRP1α is essential for nuclear protein import. EMBO J., 15, 1818-1825.
    • (1996) EMBO J. , vol.15 , pp. 1818-1825
    • Weis, K.1    Ryder, U.2    Lamond, A.I.3
  • 73
    • 0030984329 scopus 로고    scopus 로고
    • Cloning end characterization of human karyopherin beta3
    • Yaseen, N.R. and Blobel, G. (1997) Cloning end characterization of human karyopherin beta3. Proc. Natl Acad. Sci. USA, 94, 4451-4456.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 4451-4456
    • Yaseen, N.R.1    Blobel, G.2
  • 74
    • 0021052942 scopus 로고
    • tRNA transport from the nucleus in a eukaryotic cell: Carrier-mediated translocation process
    • Zasloff, M. (1983) tRNA transport from the nucleus in a eukaryotic cell: carrier-mediated translocation process. Proc. Natl Acad. Sci. USA, 80, 6436-6440.
    • (1983) Proc. Natl Acad. Sci. USA , vol.80 , pp. 6436-6440
    • Zasloff, M.1


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