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Volumn 10, Issue 4, 2014, Pages

Inactivation of Genes for Antigenic Variation in the Relapsing Fever Spirochete Borrelia hermsii Reduces Infectivity in Mice and Transmission by Ticks

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA;

EID: 84901323412     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004056     Document Type: Article
Times cited : (46)

References (84)
  • 1
    • 0033772639 scopus 로고    scopus 로고
    • Antigenic variation in vector-borne pathogens
    • Barbour AG, Restrepo BI, (2000) Antigenic variation in vector-borne pathogens. Emerg Infect Dis 6: 449-457.
    • (2000) Emerg Infect Dis , vol.6 , pp. 449-457
    • Barbour, A.G.1    Restrepo, B.I.2
  • 2
    • 84864407356 scopus 로고    scopus 로고
    • Microbial antigenic variation mediated by homologous DNA recombination
    • Vink C, Rudenko G, Seifert HS, (2012) Microbial antigenic variation mediated by homologous DNA recombination. FEMS Microbiol Rev 36: 917-948.
    • (2012) FEMS Microbiol Rev , vol.36 , pp. 917-948
    • Vink, C.1    Rudenko, G.2    Seifert, H.S.3
  • 3
    • 72749109443 scopus 로고    scopus 로고
    • Nothing is permanent but change' - antigenic variation in persistent bacterial pathogens
    • Palmer GH, Bankhead T, Lukehart SA, (2009) 'Nothing is permanent but change'- antigenic variation in persistent bacterial pathogens. Cell Microbiol 11: 1697-1705.
    • (2009) Cell Microbiol , vol.11 , pp. 1697-1705
    • Palmer, G.H.1    Bankhead, T.2    Lukehart, S.A.3
  • 4
    • 0020461166 scopus 로고
    • Antigenic variation of Borrelia hermsii
    • Stoenner HG, Dodd T, Larsen C, (1982) Antigenic variation of Borrelia hermsii. J Exp Med 156: 1297-1311.
    • (1982) J Exp Med , vol.156 , pp. 1297-1311
    • Stoenner, H.G.1    Dodd, T.2    Larsen, C.3
  • 5
    • 0022341444 scopus 로고
    • Antigenic variation is associated with DNA rearrangements in a relapsing fever Borrelia
    • Meier JT, Simon MI, Barbour AG, (1985) Antigenic variation is associated with DNA rearrangements in a relapsing fever Borrelia. Cell 41: 403-409.
    • (1985) Cell , vol.41 , pp. 403-409
    • Meier, J.T.1    Simon, M.I.2    Barbour, A.G.3
  • 6
    • 0022430232 scopus 로고
    • Transposition of structural genes to an expression sequence on a linear plasmid causes antigenic variation in the bacterium Borrelia hermsii
    • Plasterk RHA, Simon MI, Barbour AG, (1985) Transposition of structural genes to an expression sequence on a linear plasmid causes antigenic variation in the bacterium Borrelia hermsii. Nature 318: 257-263.
    • (1985) Nature , vol.318 , pp. 257-263
    • Plasterk, R.H.A.1    Simon, M.I.2    Barbour, A.G.3
  • 7
    • 0025002956 scopus 로고
    • Juxtaposition of expressed variable antigen genes with a conserved telomere in the bacterium Borrelia hermsii
    • Kitten T, Barbour AG, (1990) Juxtaposition of expressed variable antigen genes with a conserved telomere in the bacterium Borrelia hermsii. Proc Natl Acad Sci USA 87: 6077-6081.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6077-6081
    • Kitten, T.1    Barbour, A.G.2
  • 9
    • 0037377972 scopus 로고    scopus 로고
    • The resolution of relapsing fever borreliosis requires IgM and is concurrent with expansion of B1b lymphocytes
    • Alugupalli KR, Gerstein RM, Chen J, Szomolanyi-Tsuda E, Woodland RT, et al. (2003) The resolution of relapsing fever borreliosis requires IgM and is concurrent with expansion of B1b lymphocytes. J Immunol 170: 3819-3827.
    • (2003) J Immunol , vol.170 , pp. 3819-3827
    • Alugupalli, K.R.1    Gerstein, R.M.2    Chen, J.3    Szomolanyi-Tsuda, E.4    Woodland, R.T.5
  • 10
    • 0035884984 scopus 로고    scopus 로고
    • Cutting edge: the spirochetemia of murine relapsing fever is cleared by complement-independent bactericidal antibodies
    • Connolly SE, Benach JL, (2001) Cutting edge: the spirochetemia of murine relapsing fever is cleared by complement-independent bactericidal antibodies. J Immunol 167: 3029-3032.
    • (2001) J Immunol , vol.167 , pp. 3029-3032
    • Connolly, S.E.1    Benach, J.L.2
  • 11
    • 17844364491 scopus 로고    scopus 로고
    • Infection-induced marginal B cell production of Borrelia hermsii-specific antibody is impaired in the absence of CD1d1
    • Belperron AA, Dailey CM, Bockenstedt LK, (2005) Infection-induced marginal B cell production of Borrelia hermsii-specific antibody is impaired in the absence of CD1d1. J Immunol 174: 5681-5686.
    • (2005) J Immunol , vol.174 , pp. 5681-5686
    • Belperron, A.A.1    Dailey, C.M.2    Bockenstedt, L.K.3
  • 12
    • 0035140048 scopus 로고    scopus 로고
    • In vitro and in vivo neutralization of the relapsing fever agent Borrelia hermsii with serotype-specific immunoglobulin M antibodies
    • Barbour AG, Bundoc V, (2001) In vitro and in vivo neutralization of the relapsing fever agent Borrelia hermsii with serotype-specific immunoglobulin M antibodies. Infect Immun 69: 1009-1015.
    • (2001) Infect Immun , vol.69 , pp. 1009-1015
    • Barbour, A.G.1    Bundoc, V.2
  • 13
    • 0014057281 scopus 로고
    • Experimental relapsing fever initiated by Borrelia hermsi. II. Sequential appearence of major serotypes in the rat
    • Coffey EM, Eveland WC, (1967) Experimental relapsing fever initiated by Borrelia hermsi. II. Sequential appearence of major serotypes in the rat. J Infect Dis 117: 29-34.
    • (1967) J Infect Dis , vol.117 , pp. 29-34
    • Coffey, E.M.1    Eveland, W.C.2
  • 14
    • 84884813346 scopus 로고
    • Relapsing fever: a clinical and microbiological review
    • Southern PM, Sanford JP, (1968) Relapsing fever: a clinical and microbiological review. Medicine 48: 129-149.
    • (1968) Medicine , vol.48 , pp. 129-149
    • Southern, P.M.1    Sanford, J.P.2
  • 15
    • 79960513736 scopus 로고    scopus 로고
    • Acquisition and subsequent transmission of Borrelia hermsii by the soft tick Ornithodoros hermsi
    • Lopez JE, McCoy BN, Krajacich BJ, Schwan TG, (2011) Acquisition and subsequent transmission of Borrelia hermsii by the soft tick Ornithodoros hermsi. J Med Entomol 48: 891-895.
    • (2011) J Med Entomol , vol.48 , pp. 891-895
    • Lopez, J.E.1    McCoy, B.N.2    Krajacich, B.J.3    Schwan, T.G.4
  • 16
    • 33744457018 scopus 로고    scopus 로고
    • Antigenic variation by Borrelia hermsii occurs through recombination between extragenic repetitive elements on linear plasmids
    • Dai Q, Restrepo BI, Porcella SF, Raffel SJ, Schwan TG, et al. (2006) Antigenic variation by Borrelia hermsii occurs through recombination between extragenic repetitive elements on linear plasmids. Mol Microbiol 60: 1329-1343.
    • (2006) Mol Microbiol , vol.60 , pp. 1329-1343
    • Dai, Q.1    Restrepo, B.I.2    Porcella, S.F.3    Raffel, S.J.4    Schwan, T.G.5
  • 17
    • 0026446166 scopus 로고
    • Subtelomeric expression regions of Borrelia hermsii linear plasmids are highly polymorphic
    • Restrepo BI, Kitten T, Carter CJ, Infante D, Barbour AG, (1992) Subtelomeric expression regions of Borrelia hermsii linear plasmids are highly polymorphic. Mol Microbiol 6: 3299-3311.
    • (1992) Mol Microbiol , vol.6 , pp. 3299-3311
    • Restrepo, B.I.1    Kitten, T.2    Carter, C.J.3    Infante, D.4    Barbour, A.G.5
  • 18
    • 2642612784 scopus 로고    scopus 로고
    • Population structure of the relapsing fever spirochete Borrelia hermsii as indicated by polymorphism of two multigene families that encode immunogenic outer surface lipoproteins
    • Hinnebusch BJ, Barbour AG, Restrepo BI, Schwan TG (1998) Population structure of the relapsing fever spirochete Borrelia hermsii as indicated by polymorphism of two multigene families that encode immunogenic outer surface lipoproteins. Infect Immun 66: 432 - 440.
    • (1998) Infect Immun , vol.66 , pp. 432-440
    • Hinnebusch, B.J.1    Barbour, A.G.2    Restrepo, B.I.3    Schwan, T.G.4
  • 19
    • 0025977240 scopus 로고
    • Tandem insertion sequence-like elements define the expression site for variable antigen genes of Borrelia hermsii
    • Barbour AG, Carter CJ, Burman N, Freitag CS, Garon CF, et al. (1991) Tandem insertion sequence-like elements define the expression site for variable antigen genes of Borrelia hermsii. Infect Immun 59: 390-397.
    • (1991) Infect Immun , vol.59 , pp. 390-397
    • Barbour, A.G.1    Carter, C.J.2    Burman, N.3    Freitag, C.S.4    Garon, C.F.5
  • 20
    • 0026019785 scopus 로고
    • Variable antigen genes of the relapsing fever agent Borrelia hermsii are activated by promoter addition
    • Barbour AG, Burman N, Carter CJ, Kitten T, Bergstrom S, (1991) Variable antigen genes of the relapsing fever agent Borrelia hermsii are activated by promoter addition. Mol Microbiol 5: 489-493.
    • (1991) Mol Microbiol , vol.5 , pp. 489-493
    • Barbour, A.G.1    Burman, N.2    Carter, C.J.3    Kitten, T.4    Bergstrom, S.5
  • 21
    • 0027965079 scopus 로고
    • Antigen diversity in the bacterium B. hermsii through "somatic" mutations in rearranged vmp genes
    • Restrepo BI, Barbour AG, (1994) Antigen diversity in the bacterium B. hermsii through "somatic" mutations in rearranged vmp genes. Cell 78: 867-876.
    • (1994) Cell , vol.78 , pp. 867-876
    • Restrepo, B.I.1    Barbour, A.G.2
  • 22
    • 0345643491 scopus 로고    scopus 로고
    • The extended promoters for two outer membrane lipoprotein genes of Borrelia spp. uniquely include a T-rich region
    • Sohaskey CD, Zuckert WR, Barbour AG, (1999) The extended promoters for two outer membrane lipoprotein genes of Borrelia spp. uniquely include a T-rich region. Mol Microbiol 33: 41-51.
    • (1999) Mol Microbiol , vol.33 , pp. 41-51
    • Sohaskey, C.D.1    Zuckert, W.R.2    Barbour, A.G.3
  • 23
    • 0032546854 scopus 로고    scopus 로고
    • Bloodstream- versus tick-associated variants of a relapsing fever bacterium
    • Schwan TG, Hinnebusch BJ, (1998) Bloodstream- versus tick-associated variants of a relapsing fever bacterium. Science 280: 1938-1940.
    • (1998) Science , vol.280 , pp. 1938-1940
    • Schwan, T.G.1    Hinnebusch, B.J.2
  • 24
    • 1342318504 scopus 로고    scopus 로고
    • Antigenic variation in Borrelia: relapsing fever and Lyme borreliosis
    • In: Craig A, Scherf A, editors, London: Academic Press
    • Barbour AG (2003) Antigenic variation in Borrelia: relapsing fever and Lyme borreliosis. In: Craig A, Scherf A, editors. Antigenic Variation. London: Academic Press. pp. 319-356.
    • (2003) Antigenic Variation , pp. 319-356
    • Barbour, A.G.1
  • 25
    • 0028227847 scopus 로고
    • A family of surface-exposed proteins of 20 kilodaltons in the genus Borrelia
    • Carter CJ, Bergstrom S, Norris SJ, Barbour AG, (1994) A family of surface-exposed proteins of 20 kilodaltons in the genus Borrelia. Infect Immun 62: 2792-2799.
    • (1994) Infect Immun , vol.62 , pp. 2792-2799
    • Carter, C.J.1    Bergstrom, S.2    Norris, S.J.3    Barbour, A.G.4
  • 26
    • 0034445518 scopus 로고    scopus 로고
    • Surface protein variation by expression site switching in the relapsing fever agent Borrelia hermsii
    • Barbour AG, Carter CJ, Sohaskey CD, (2000) Surface protein variation by expression site switching in the relapsing fever agent Borrelia hermsii. Infect Immun 68: 7114-7121.
    • (2000) Infect Immun , vol.68 , pp. 7114-7121
    • Barbour, A.G.1    Carter, C.J.2    Sohaskey, C.D.3
  • 27
    • 25444515681 scopus 로고    scopus 로고
    • Variable tick protein in two genomic groups of the relapsing fever spirochete Borrelia hermsii in western North America
    • Porcella SF, Raffel SJ, Anderson Jr DE, Gilk SD, Bono JL, et al. (2005) Variable tick protein in two genomic groups of the relapsing fever spirochete Borrelia hermsii in western North America. Infect Immun 73: 6647-6658.
    • (2005) Infect Immun , vol.73 , pp. 6647-6658
    • Porcella, S.F.1    Raffel, S.J.2    Anderson Jr., D.E.3    Gilk, S.D.4    Bono, J.L.5
  • 28
    • 40549120963 scopus 로고    scopus 로고
    • A system for site-specific genetic manipulation of the relapsing fever spirochete Borrelia hermsii
    • In: DeLeo FR, Otto M, editors, Totowa: Humana Press
    • Battisti JM, Raffel SJ, Schwan TG (2008) A system for site-specific genetic manipulation of the relapsing fever spirochete Borrelia hermsii. In: DeLeo FR, Otto M, editors. Methods in Molecular Biology 431: Bacterial Pathogenesis Methods and Protocols. Totowa: Humana Press. pp. 69-84.
    • (2008) Methods in Molecular Biology 431: Bacterial Pathogenesis Methods and Protocols , pp. 69-84
    • Battisti, J.M.1    Raffel, S.J.2    Schwan, T.G.3
  • 29
    • 21244445445 scopus 로고    scopus 로고
    • Mapping of essential replication functions of the linear plasmid lp17 of B. burgdorferi by targeted deletion walking
    • Beaurepaire C, Chaconas G, (2005) Mapping of essential replication functions of the linear plasmid lp17 of B. burgdorferi by targeted deletion walking. Mol Microbiol 57: 132-142.
    • (2005) Mol Microbiol , vol.57 , pp. 132-142
    • Beaurepaire, C.1    Chaconas, G.2
  • 30
    • 4644249919 scopus 로고    scopus 로고
    • Experimental assessment of the roles of linear plasmids lp25 and lp28-1 of Borrelia burgdorferi throughout the infectious cycle
    • Grimm D, Eggers CH, Caimano MJ, Tilly K, Stewart PE, et al. (2004) Experimental assessment of the roles of linear plasmids lp25 and lp28-1 of Borrelia burgdorferi throughout the infectious cycle. Infect Immun 72: 5938-5946.
    • (2004) Infect Immun , vol.72 , pp. 5938-5946
    • Grimm, D.1    Eggers, C.H.2    Caimano, M.J.3    Tilly, K.4    Stewart, P.E.5
  • 31
    • 15044360687 scopus 로고    scopus 로고
    • The plasmids of Borrelia burgdorferi: essential genetic elements of a pathogen
    • Stewart PE, Byram R, Grimm D, Tilly K, Rosa PA, (2005) The plasmids of Borrelia burgdorferi: essential genetic elements of a pathogen. Plasmid 53: 1-13.
    • (2005) Plasmid , vol.53 , pp. 1-13
    • Stewart, P.E.1    Byram, R.2    Grimm, D.3    Tilly, K.4    Rosa, P.A.5
  • 32
    • 0035131631 scopus 로고    scopus 로고
    • Isolation of a circular plasmid region sufficient for autonomous replication and transformation of infectious Borrelia burgdorferi
    • Stewart PE, Thalken R, Bono JL, Rosa P, (2001) Isolation of a circular plasmid region sufficient for autonomous replication and transformation of infectious Borrelia burgdorferi. Mol Microbiol 39: 714-721.
    • (2001) Mol Microbiol , vol.39 , pp. 714-721
    • Stewart, P.E.1    Thalken, R.2    Bono, J.L.3    Rosa, P.4
  • 33
    • 34249820286 scopus 로고    scopus 로고
    • The critical role of the linear plasmid lp36 in the infectious cycle of Borrelia burgdorferi
    • Jewett MW, Lawrence K, Bestor AC, Tilly K, Grimm D, et al. (2007) The critical role of the linear plasmid lp36 in the infectious cycle of Borrelia burgdorferi. Mol Microbiol 64: 1358-1374.
    • (2007) Mol Microbiol , vol.64 , pp. 1358-1374
    • Jewett, M.W.1    Lawrence, K.2    Bestor, A.C.3    Tilly, K.4    Grimm, D.5
  • 34
    • 80052325574 scopus 로고    scopus 로고
    • Borrelia burgdorferi linear plasmid 38 is dispensable for completion of the mouse-tick infectious cycle
    • Dulebohn DP, Bestor A, Rego RO, Stewart PE, Rosa PA, (2011) Borrelia burgdorferi linear plasmid 38 is dispensable for completion of the mouse-tick infectious cycle. Infect Immun 79: 3510-3517.
    • (2011) Infect Immun , vol.79 , pp. 3510-3517
    • Dulebohn, D.P.1    Bestor, A.2    Rego, R.O.3    Stewart, P.E.4    Rosa, P.A.5
  • 35
    • 78649341681 scopus 로고    scopus 로고
    • Bloodmeal size and spirochete acquisition of Ornithodoros hermsi (Acari: Argasidae) during feeding
    • McCoy BN, Raffel SJ, Lopez JE, Schwan TG, (2010) Bloodmeal size and spirochete acquisition of Ornithodoros hermsi (Acari: Argasidae) during feeding. J Med Entomol 47: 1164-1172.
    • (2010) J Med Entomol , vol.47 , pp. 1164-1172
    • McCoy, B.N.1    Raffel, S.J.2    Lopez, J.E.3    Schwan, T.G.4
  • 36
    • 0030904280 scopus 로고    scopus 로고
    • Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes
    • Zhang J-R, Hardham JM, Barbour AG, Norris SJ, (1997) Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes. Cell 89: 275-285.
    • (1997) Cell , vol.89 , pp. 275-285
    • Zhang, J.-R.1    Hardham, J.M.2    Barbour, A.G.3    Norris, S.J.4
  • 37
    • 33744457946 scopus 로고    scopus 로고
    • Antigenic variation with a twist - the Borrelia story
    • Norris SJ, (2006) Antigenic variation with a twist- the Borrelia story. Mol Microbiol 60: 1319-1322.
    • (2006) Mol Microbiol , vol.60 , pp. 1319-1322
    • Norris, S.J.1
  • 39
    • 0027963449 scopus 로고
    • Expression and gene sequence of outer surface protein C of Borrelia burgdorferi reisolated from chronically infected mice
    • Stevenson B, Bockenstedt LK, Barthold SW, (1994) Expression and gene sequence of outer surface protein C of Borrelia burgdorferi reisolated from chronically infected mice. Infect Immun 62: 3568-3571.
    • (1994) Infect Immun , vol.62 , pp. 3568-3571
    • Stevenson, B.1    Bockenstedt, L.K.2    Barthold, S.W.3
  • 40
    • 0025775837 scopus 로고
    • Changes in antigenic reactivity of Borrelia burgdorferi, the Lyme disease spirochete, during persistent infection in mice
    • Schwan TG, Karstens RH, Schrumpf ME, Simpson WJ, (1991) Changes in antigenic reactivity of Borrelia burgdorferi, the Lyme disease spirochete, during persistent infection in mice. Can J Microbiol 37: 450-454.
    • (1991) Can J Microbiol , vol.37 , pp. 450-454
    • Schwan, T.G.1    Karstens, R.H.2    Schrumpf, M.E.3    Simpson, W.J.4
  • 41
    • 0021811823 scopus 로고
    • Mice as reservoirs of the Lyme disease spirochete
    • Levine JF, Wilson ML, Spielman A, (1985) Mice as reservoirs of the Lyme disease spirochete. Am J Trop Med Hyg 34: 355-360.
    • (1985) Am J Trop Med Hyg , vol.34 , pp. 355-360
    • Levine, J.F.1    Wilson, M.L.2    Spielman, A.3
  • 42
    • 0023134510 scopus 로고
    • Reservoir competence of white-footed mice for Lyme disease spirochetes
    • Donahue JG, Piesman J, Spielman A, (1987) Reservoir competence of white-footed mice for Lyme disease spirochetes. Am J Trop Med Hyg 36: 92-96.
    • (1987) Am J Trop Med Hyg , vol.36 , pp. 92-96
    • Donahue, J.G.1    Piesman, J.2    Spielman, A.3
  • 43
    • 0025835678 scopus 로고
    • Lyme borreliosis: a relapsing fever-like disease
    • Burgdorfer W, Schwan TG (1991) Lyme borreliosis: a relapsing fever-like disease. Scand J Infect Dis Suppl. 77: 17-22.
    • (1991) Scand J Infect Dis Suppl , vol.77 , pp. 17-22
    • Burgdorfer, W.1    Schwan, T.G.2
  • 44
    • 0034610332 scopus 로고    scopus 로고
    • Correlation between plasmid content and infectivity in Borrelia burgdorferi
    • Purser JE, Norris SJ, (2000) Correlation between plasmid content and infectivity in Borrelia burgdorferi. Proc Natl Acad Sci U S A 97: 13865-13870.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 13865-13870
    • Purser, J.E.1    Norris, S.J.2
  • 45
    • 34548309048 scopus 로고    scopus 로고
    • The role of VlsE antigenic variation in the Lyme disease spirochete: persistence through a mechanism that differes from other pathogens
    • Bankhead T, Chaconas G, (2007) The role of VlsE antigenic variation in the Lyme disease spirochete: persistence through a mechanism that differes from other pathogens. Mol Microbiol 65: 1547-1558.
    • (2007) Mol Microbiol , vol.65 , pp. 1547-1558
    • Bankhead, T.1    Chaconas, G.2
  • 46
    • 0015245768 scopus 로고
    • Cultivation of Borrelia hermsi
    • Kelly R, (1971) Cultivation of Borrelia hermsi. Science 173: 443-444.
    • (1971) Science , vol.173 , pp. 443-444
    • Kelly, R.1
  • 48
    • 0023753146 scopus 로고
    • Changes in infectivity and plasmid profile of the Lyme disease spirochete, Borrelia burgdorferi, as a result of in vitro cultivation
    • Schwan TG, Burgdorfer W, Garon CF, (1988) Changes in infectivity and plasmid profile of the Lyme disease spirochete, Borrelia burgdorferi, as a result of in vitro cultivation. Infect Immun 56: 1831-1836.
    • (1988) Infect Immun , vol.56 , pp. 1831-1836
    • Schwan, T.G.1    Burgdorfer, W.2    Garon, C.F.3
  • 49
    • 0023874680 scopus 로고
    • Plasmid analysis of Borrelia burgdorferi, the Lyme disease agent
    • Barbour AG, (1988) Plasmid analysis of Borrelia burgdorferi, the Lyme disease agent. J Clin Microbiol 26: 475-478.
    • (1988) J Clin Microbiol , vol.26 , pp. 475-478
    • Barbour, A.G.1
  • 50
    • 0020383013 scopus 로고
    • Variable major proteins of Borrelia hermsii
    • Barbour AG, Tessier SL, Stoenner HG, (1982) Variable major proteins of Borrelia hermsii. J Exp Med 156: 1312-1324.
    • (1982) J Exp Med , vol.156 , pp. 1312-1324
    • Barbour, A.G.1    Tessier, S.L.2    Stoenner, H.G.3
  • 51
    • 0021882523 scopus 로고
    • Variable major proteins of Borrelia hermsii. Epitope mapping and partial sequence analysis of CNBr peptides
    • Barstad PA, Coligan JE, Raum MG, Barbour AG, (1985) Variable major proteins of Borrelia hermsii. Epitope mapping and partial sequence analysis of CNBr peptides. J Exp Med 161: 1302-1314.
    • (1985) J Exp Med , vol.161 , pp. 1302-1314
    • Barstad, P.A.1    Coligan, J.E.2    Raum, M.G.3    Barbour, A.G.4
  • 52
    • 44449113837 scopus 로고    scopus 로고
    • Bactericidal action of a complement-independent antibody against relapsing fever Borrelia resides in its variable region
    • LaRocca TJ, Katona LI, Thanassi DG, Benach JL, (2008) Bactericidal action of a complement-independent antibody against relapsing fever Borrelia resides in its variable region. J Immunol 180: 6222-6228.
    • (2008) J Immunol , vol.180 , pp. 6222-6228
    • LaRocca, T.J.1    Katona, L.I.2    Thanassi, D.G.3    Benach, J.L.4
  • 53
    • 0035151055 scopus 로고    scopus 로고
    • Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin ∂llb β3 activation
    • Alugupalli KR, Michelson AD, Bernard MR, Robbins D, Coburn J, et al. (2001) Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin ∂llb β3 activation. Mol Microbiol 39: 330-340.
    • (2001) Mol Microbiol , vol.39 , pp. 330-340
    • Alugupalli, K.R.1    Michelson, A.D.2    Bernard, M.R.3    Robbins, D.4    Coburn, J.5
  • 54
    • 0141889318 scopus 로고    scopus 로고
    • Spirochete-platelet attachment and thrombocytopenia in murine relapsing fever borreliosis
    • Alugupalli KR, Michelson AD, Joris I, Schwan TG, Hodivala-Dilke K, et al. (2003) Spirochete-platelet attachment and thrombocytopenia in murine relapsing fever borreliosis. Blood 102: 2843-2850.
    • (2003) Blood , vol.102 , pp. 2843-2850
    • Alugupalli, K.R.1    Michelson, A.D.2    Joris, I.3    Schwan, T.G.4    Hodivala-Dilke, K.5
  • 55
    • 23944481424 scopus 로고    scopus 로고
    • Horizontally acquired genes for purine salvage in Borrelia spp. causing relapsing fever
    • Barbour AG, Putteeet-Driver AD, Bunikis J, (2005) Horizontally acquired genes for purine salvage in Borrelia spp. causing relapsing fever. Infect Immun 73: 6165-6168.
    • (2005) Infect Immun , vol.73 , pp. 6165-6168
    • Barbour, A.G.1    Putteeet-Driver, A.D.2    Bunikis, J.3
  • 56
    • 0037315021 scopus 로고    scopus 로고
    • Glycerol-3-phosphate acquisition in spirochetes: distribution and biological activity of glycerophosphodiester phosphodiesterase (GlpQ) among Borrelia spirochetes
    • Schwan TG, Battisti JM, Porcella SF, Raffel SJ, Schrumpf ME, et al. (2003) Glycerol-3-phosphate acquisition in spirochetes: distribution and biological activity of glycerophosphodiester phosphodiesterase (GlpQ) among Borrelia spirochetes. J Bacteriol 185: 1346-1356.
    • (2003) J Bacteriol , vol.185 , pp. 1346-1356
    • Schwan, T.G.1    Battisti, J.M.2    Porcella, S.F.3    Raffel, S.J.4    Schrumpf, M.E.5
  • 58
    • 76749111626 scopus 로고    scopus 로고
    • Genetic control of the innate immune response to Borrelia hermsii influences the course of relapsing fever in inbred strains of mice
    • Benoit VM, Petrich A, Alugupalli KR, Marty-Roix R, Moter A, et al. (2010) Genetic control of the innate immune response to Borrelia hermsii influences the course of relapsing fever in inbred strains of mice. Infect Immun 78: 586-594.
    • (2010) Infect Immun , vol.78 , pp. 586-594
    • Benoit, V.M.1    Petrich, A.2    Alugupalli, K.R.3    Marty-Roix, R.4    Moter, A.5
  • 59
    • 17644374221 scopus 로고    scopus 로고
    • Relapsing fever spirochetes contain chromosomal genes with unique direct tandemly repeated sequences
    • Guyard C, Chester EM, Raffel SJ, Schrumpf ME, Policastro PF, et al. (2005) Relapsing fever spirochetes contain chromosomal genes with unique direct tandemly repeated sequences. Infect Immun 73: 3025-3037.
    • (2005) Infect Immun , vol.73 , pp. 3025-3037
    • Guyard, C.1    Chester, E.M.2    Raffel, S.J.3    Schrumpf, M.E.4    Policastro, P.F.5
  • 60
    • 79958160049 scopus 로고    scopus 로고
    • Pathogenesis of relapsing fever
    • In: Samuels DS, Radolf JD, editors, Norfolk, UK: Caister Academic Press
    • Barbour AG, Guo BP (2010) Pathogenesis of relapsing fever. In: Samuels DS, Radolf JD, editors. Borrelia: molecular biology, host interaction and pathogenesis. Norfolk, UK: Caister Academic Press. pp. 333-357.
    • (2010) Borrelia: Molecular biology, host interaction and pathogenesis , pp. 333-357
    • Barbour, A.G.1    Guo, B.P.2
  • 61
    • 0034783107 scopus 로고    scopus 로고
    • Analysis of Borrelia burgdorferi vlsE gene expression and recombination in the tick vector
    • Indest KJ, Howell JK, Jacobs MB, Scholl-Meeker D, Norris SJ, et al. (2001) Analysis of Borrelia burgdorferi vlsE gene expression and recombination in the tick vector. Infect Immun 69: 7083-7090.
    • (2001) Infect Immun , vol.69 , pp. 7083-7090
    • Indest, K.J.1    Howell, J.K.2    Jacobs, M.B.3    Scholl-Meeker, D.4    Norris, S.J.5
  • 62
    • 0038444338 scopus 로고    scopus 로고
    • Genetic variation at the vlsE locus of Borrelia burgdorferi within ticks and mice over the course of a single transmission cycle
    • Ohnishi J, Schneider B, Messer WB, Piesman J, de Silva AM, (2003) Genetic variation at the vlsE locus of Borrelia burgdorferi within ticks and mice over the course of a single transmission cycle. J Bacteriol 185: 4432-4441.
    • (2003) J Bacteriol , vol.185 , pp. 4432-4441
    • Ohnishi, J.1    Schneider, B.2    Messer, W.B.3    Piesman, J.4    de Silva, A.M.5
  • 63
    • 33745442559 scopus 로고    scopus 로고
    • Transcriptional regulation of the Borrelia burgdorferi antigenically variable VlsE surface protein
    • Bykowski T, Babb K, von Lackum K, Riley SP, Norris SJ, et al. (2006) Transcriptional regulation of the Borrelia burgdorferi antigenically variable VlsE surface protein. J Bacteriol 188: 4879-4889.
    • (2006) J Bacteriol , vol.188 , pp. 4879-4889
    • Bykowski, T.1    Babb, K.2    von Lackum, K.3    Riley, S.P.4    Norris, S.J.5
  • 64
    • 33847696190 scopus 로고    scopus 로고
    • Lack of detectable variation at Borrelia burgdorferi vlsE locus in ticks
    • Nosbisch LK, de Silva AM, (2007) Lack of detectable variation at Borrelia burgdorferi vlsE locus in ticks. J Med Entomol 44: 168-170.
    • (2007) J Med Entomol , vol.44 , pp. 168-170
    • Nosbisch, L.K.1    de Silva, A.M.2
  • 65
  • 66
    • 0033984294 scopus 로고    scopus 로고
    • Temporal changes in outer surface proteins A and C of the Lyme disease-associated spirochete, Borrelia burgdorferi, during the chain of infection in ticks and mice
    • Schwan TG, Piesman J, (2000) Temporal changes in outer surface proteins A and C of the Lyme disease-associated spirochete, Borrelia burgdorferi, during the chain of infection in ticks and mice. J Clin Microbiol 38: 383-388.
    • (2000) J Clin Microbiol , vol.38 , pp. 383-388
    • Schwan, T.G.1    Piesman, J.2
  • 67
    • 0037326941 scopus 로고    scopus 로고
    • Temporal regulation of outer surface proteins of the Lyme-disease spirochaete Borrelia burgdorferi
    • Schwan TG, (2003) Temporal regulation of outer surface proteins of the Lyme-disease spirochaete Borrelia burgdorferi. Biochem Soc Trans 31: 108-112.
    • (2003) Biochem Soc Trans , vol.31 , pp. 108-112
    • Schwan, T.G.1
  • 68
    • 0031587871 scopus 로고    scopus 로고
    • Plasminogen is required for efficient dissemination of B. burgdorferi in ticks and for enhancement of spirochetemia in mice
    • Coleman JL, Gebbia JA, Piesman J, Degen JL, Bugge TH, et al. (1997) Plasminogen is required for efficient dissemination of B. burgdorferi in ticks and for enhancement of spirochetemia in mice. Cell 89: 1111-1119.
    • (1997) Cell , vol.89 , pp. 1111-1119
    • Coleman, J.L.1    Gebbia, J.A.2    Piesman, J.3    Degen, J.L.4    Bugge, T.H.5
  • 69
    • 12144289145 scopus 로고    scopus 로고
    • Outer-surface protein C of the Lyme disease spirochete: A protein induced in ticks for infection of mammals
    • Grimm D, Tilly K, Byram R, Stewart PE, Krum JG, et al. (2004) Outer-surface protein C of the Lyme disease spirochete: A protein induced in ticks for infection of mammals. Proc Natl Acad Sci USA 101: 3142-3147.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3142-3147
    • Grimm, D.1    Tilly, K.2    Byram, R.3    Stewart, P.E.4    Krum, J.G.5
  • 70
    • 80053278392 scopus 로고    scopus 로고
    • Gene regulation in Borrelia burgdorferi
    • Samuels DS, (2011) Gene regulation in Borrelia burgdorferi. Annu Rev Microbiol 65: 479-499.
    • (2011) Annu Rev Microbiol , vol.65 , pp. 479-499
    • Samuels, D.S.1
  • 71
    • 0028828202 scopus 로고
    • Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi
    • Stevenson B, Schwan TG, Rosa PA, (1995) Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi. Infect Immun 63: 4535-4539.
    • (1995) Infect Immun , vol.63 , pp. 4535-4539
    • Stevenson, B.1    Schwan, T.G.2    Rosa, P.A.3
  • 72
    • 84873542723 scopus 로고    scopus 로고
    • Changes in bacterial growth rate govern expression of the Borrelia burgdorferi OspC and Erp infection-associated surface proteins
    • Jutras BL, Chenail AM, Stevenson B, (2013) Changes in bacterial growth rate govern expression of the Borrelia burgdorferi OspC and Erp infection-associated surface proteins. J Bacteriol 195: 757-764.
    • (2013) J Bacteriol , vol.195 , pp. 757-764
    • Jutras, B.L.1    Chenail, A.M.2    Stevenson, B.3
  • 73
    • 84861137833 scopus 로고    scopus 로고
    • Alp, an arthropod-associated outer membrane protein of Borrelia species that cause relapsing fever
    • Marcsisin RA, Campeau SA, Lopez JE, Barbour AG, (2012) Alp, an arthropod-associated outer membrane protein of Borrelia species that cause relapsing fever. Infect Immun 80: 1881-1890.
    • (2012) Infect Immun , vol.80 , pp. 1881-1890
    • Marcsisin, R.A.1    Campeau, S.A.2    Lopez, J.E.3    Barbour, A.G.4
  • 74
    • 79952159926 scopus 로고    scopus 로고
    • Evolution and distribution of the ospC gene, a transferable serotype determinant of Borrelia burgdorferi
    • Barbour AG, Travinsky B, (2010) Evolution and distribution of the ospC gene, a transferable serotype determinant of Borrelia burgdorferi. mBio 1: e00153-00110.
    • (2010) MBio , vol.1
    • Barbour, A.G.1    Travinsky, B.2
  • 75
    • 0027362782 scopus 로고
    • Polymorphism in ospC gene of Borrelia burgdorferi and immunoreactivity of OspC protein: implications for taxonomy and for use of OspC protein as a diagnostic antigen
    • Theisen M, Frederiksen B, Lebech A-M, Vuust J, Hansen K, (1993) Polymorphism in ospC gene of Borrelia burgdorferi and immunoreactivity of OspC protein: implications for taxonomy and for use of OspC protein as a diagnostic antigen. J Clin Microbiol 31: 2570-2576.
    • (1993) J Clin Microbiol , vol.31 , pp. 2570-2576
    • Theisen, M.1    Frederiksen, B.2    Lebech, A.-M.3    Vuust, J.4    Hansen, K.5
  • 77
    • 0028241233 scopus 로고
    • Activation of a vmp pseudogene in Borrelia hermsii: an alternate mechanism of antigenic variation during relapsing fever
    • Restrepo BI, Carter CJ, Barbour AG, (1994) Activation of a vmp pseudogene in Borrelia hermsii: an alternate mechanism of antigenic variation during relapsing fever. Mol Microbiol 13: 287-299.
    • (1994) Mol Microbiol , vol.13 , pp. 287-299
    • Restrepo, B.I.1    Carter, C.J.2    Barbour, A.G.3
  • 78
    • 0021671855 scopus 로고
    • Isolation and cultivation of Lyme disease spirochetes
    • Barbour AG, (1984) Isolation and cultivation of Lyme disease spirochetes. Yale J Biol Med 57: 521-525.
    • (1984) Yale J Biol Med , vol.57 , pp. 521-525
    • Barbour, A.G.1
  • 79
    • 0024992289 scopus 로고
    • Analysis of supercoiled circular plasmids in infectious and non-infectious Borrelia burgdorferi
    • Simpson WJ, Garon CF, Schwan TG, (1990) Analysis of supercoiled circular plasmids in infectious and non-infectious Borrelia burgdorferi. Microb Pathogen 8: 109-118.
    • (1990) Microb Pathogen , vol.8 , pp. 109-118
    • Simpson, W.J.1    Garon, C.F.2    Schwan, T.G.3
  • 80
    • 23744496765 scopus 로고    scopus 로고
    • Phylogenetic analysis of the spirochetes Borrelia parkeri and Borrelia turicatae and the potential for tick-borne relasping fever in Florida
    • Schwan TG, Raffel SJ, Schrumpf ME, Policastro PF, Rawlings JA, et al. (2005) Phylogenetic analysis of the spirochetes Borrelia parkeri and Borrelia turicatae and the potential for tick-borne relasping fever in Florida. J Clin Microbiol 43: 3851-3859.
    • (2005) J Clin Microbiol , vol.43 , pp. 3851-3859
    • Schwan, T.G.1    Raffel, S.J.2    Schrumpf, M.E.3    Policastro, P.F.4    Rawlings, J.A.5
  • 81
    • 0025287847 scopus 로고
    • Reactivity of human Lyme borreliosis sera with a 39-kilodalton antigen specific to Borrelia burgdorferi
    • Simpson WJ, Schrumpf ME, Schwan TG, (1990) Reactivity of human Lyme borreliosis sera with a 39-kilodalton antigen specific to Borrelia burgdorferi. J Clin Microbiol 28: 1329-1337.
    • (1990) J Clin Microbiol , vol.28 , pp. 1329-1337
    • Simpson, W.J.1    Schrumpf, M.E.2    Schwan, T.G.3
  • 82
    • 0023071673 scopus 로고
    • Immunobiology of relapsing fever
    • In: Cruse JM, Lewis RE, Jr., editors, Basel: Karger
    • Barbour AG (1987) Immunobiology of relapsing fever. In: Cruse JM, Lewis RE, Jr., editors. Contributions to Microbiology and Immunology. Basel: Karger. pp. 125-137.
    • (1987) Contributions to Microbiology and Immunology , pp. 125-137
    • Barbour, A.G.1
  • 83
    • 0024434520 scopus 로고
    • Antibody response in white-footed mice (Peromyscus leucopus) experimentally infected with the Lyme disease spirochete (Borrelia burgdorferi)
    • Schwan TG, Kime KK, Schrumpf ME, Coe JE, Simpson WJ, (1989) Antibody response in white-footed mice (Peromyscus leucopus) experimentally infected with the Lyme disease spirochete (Borrelia burgdorferi). Infect Immun 57: 3445-3451.
    • (1989) Infect Immun , vol.57 , pp. 3445-3451
    • Schwan, T.G.1    Kime, K.K.2    Schrumpf, M.E.3    Coe, J.E.4    Simpson, W.J.5
  • 84


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