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Volumn 8, Issue 6, 2008, Pages 813-820

Relapsing fever spirochetes retain infectivity after prolonged in vitro cultivation

Author keywords

Borrelia; Genetics; Vector borne

Indexed keywords

DNA;

EID: 57749090197     PISSN: 15303667     EISSN: None     Source Type: Journal    
DOI: 10.1089/vbz.2008.0033     Document Type: Article
Times cited : (27)

References (52)
  • 1
    • 0021671855 scopus 로고
    • Isolation and cultivation of Lyme disease spirochetes
    • Barbour, AG. Isolation and cultivation of Lyme disease spirochetes. Yale J Biol Med 1984; 57:521-525.
    • (1984) Yale J Biol Med , vol.57 , pp. 521-525
    • Barbour, A.G.1
  • 2
    • 0023874680 scopus 로고
    • Plasmid analysis of Borrelia burgdorferi, the Lyme disease agent
    • Barbour, AG. Plasmid analysis of Borrelia burgdorferi, the Lyme disease agent. J Clin Microbiol 1988; 26:475-478.
    • (1988) J Clin Microbiol , vol.26 , pp. 475-478
    • Barbour, A.G.1
  • 3
    • 0020533674 scopus 로고
    • Isolation of a cultivable spirochete from Ixodes ricinus ticks of Switzerland
    • Barbour, AG, Burgdorfer, W, Hayes, SF, Peter, O, et al. Isolation of a cultivable spirochete from Ixodes ricinus ticks of Switzerland. Curr Microbiol 1983; 8:123-126.
    • (1983) Curr Microbiol , vol.8 , pp. 123-126
    • Barbour, A.G.1    Burgdorfer, W.2    Hayes, S.F.3    Peter, O.4
  • 4
    • 33845329168 scopus 로고    scopus 로고
    • Pathogen escape from host immunity by a genome program for antigenic variation
    • Barbour, AG, Dai, Q, Restrepo, BI, Stoenner, HG, et al. Pathogen escape from host immunity by a genome program for antigenic variation. Proc Natl Acad Sci U S A 2006; 103:18290-18295.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 18290-18295
    • Barbour, A.G.1    Dai, Q.2    Restrepo, B.I.3    Stoenner, H.G.4
  • 5
    • 40549120963 scopus 로고    scopus 로고
    • A system for site-specific genetic manipulation of the relapsing fever spirochete Borrelia hermsii
    • DeLeo, FR, Otto, M, eds, Totowa, Humana Press
    • Battisti, JM, Raffel, SJ, Schwan, TG, et al. A system for site-specific genetic manipulation of the relapsing fever spirochete Borrelia hermsii. In: DeLeo, FR, Otto, M, eds. Methods in Molecular Biology 431: Bacterial Pathogenesis Methods and Protocols. Totowa, Humana Press, 2008; 431:69-84.
    • (2008) Methods in Molecular Biology 431: Bacterial Pathogenesis Methods and Protocols , vol.431 , pp. 69-84
    • Battisti, J.M.1    Raffel, S.J.2    Schwan, T.G.3
  • 6
    • 0020662118 scopus 로고
    • Spirochetes isolated from the blood of two patients with Lyme disease
    • Benach, JL, Bosler, EM, Hanrahan, JP, Coleman, JL, et al. Spirochetes isolated from the blood of two patients with Lyme disease. N Engl J Med 1983; 308:740-742.
    • (1983) N Engl J Med , vol.308 , pp. 740-742
    • Benach, J.L.1    Bosler, E.M.2    Hanrahan, J.P.3    Coleman, J.L.4
  • 8
    • 0031081253 scopus 로고    scopus 로고
    • Long-term in vitro cultivation of Borrelia burgdorferi sensu lato strains: Influence on plasmid patterns, genome stability and expression of proteins
    • Busch, U, Will, G, Hizo-Teufel, C, Wilske, B, et al. Long-term in vitro cultivation of Borrelia burgdorferi sensu lato strains: influence on plasmid patterns, genome stability and expression of proteins. Res Microbiol 1997; 148:109-118.
    • (1997) Res Microbiol , vol.148 , pp. 109-118
    • Busch, U.1    Will, G.2    Hizo-Teufel, C.3    Wilske, B.4
  • 9
    • 2442645223 scopus 로고    scopus 로고
    • The essential nature of the ubiquitous 26-kilobase circular replicon of Borrelia burgdorferi
    • Byram, R, Stewart, PE, Rosa, P. The essential nature of the ubiquitous 26-kilobase circular replicon of Borrelia burgdorferi. J Bacteriol 2004; 186:3561-3569.
    • (2004) J Bacteriol , vol.186 , pp. 3561-3569
    • Byram, R.1    Stewart, P.E.2    Rosa, P.3
  • 10
    • 0033975239 scopus 로고    scopus 로고
    • A bacterial genome in flux: The twelve linear and nine circular extra-chromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferi
    • Casjens, S, Palmer, N, van Vugt, R, Huang, WM, et al. A bacterial genome in flux: the twelve linear and nine circular extra-chromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferi. Mol Microbiol 2000; 35:490-516.
    • (2000) Mol Microbiol , vol.35 , pp. 490-516
    • Casjens, S.1    Palmer, N.2    van Vugt, R.3    Huang, W.M.4
  • 11
    • 0014053878 scopus 로고
    • Experimental relapsing fever initiated by Borrelia hermsi. I. Identification of major serotypes by immunofluorescence
    • Coffey, EM, Eveland, WC. Experimental relapsing fever initiated by Borrelia hermsi. I. Identification of major serotypes by immunofluorescence. J Infect Dis 1967a; 117:23-28.
    • (1967) J Infect Dis , vol.117 , pp. 23-28
    • Coffey, E.M.1    Eveland, W.C.2
  • 12
    • 0014057281 scopus 로고
    • Experimental relapsing fever initiated by Borrelia hermsi. II. Sequential appearance of major serotypes in the rat
    • Coffey, EM, Eveland, WC. Experimental relapsing fever initiated by Borrelia hermsi. II. Sequential appearance of major serotypes in the rat. J Infect Dis 1967b; 117:29-34.
    • (1967) J Infect Dis , vol.117 , pp. 29-34
    • Coffey, E.M.1    Eveland, W.C.2
  • 13
    • 44449145062 scopus 로고    scopus 로고
    • Complement factor H-binding protein, a putative virulence determinant of Borrelia hermsii, is an antigenic target for protective B1b lymphocytes
    • Colombo, MJ, Alugupalli, KR. Complement factor H-binding protein, a putative virulence determinant of Borrelia hermsii, is an antigenic target for protective B1b lymphocytes. J Immunol 2008; 180:4858-4864.
    • (2008) J Immunol , vol.180 , pp. 4858-4864
    • Colombo, M.J.1    Alugupalli, K.R.2
  • 14
    • 33744457018 scopus 로고    scopus 로고
    • Antigenic variation by Borrelia hermsii occurs through recombination between extragenic repetitive elements on linear plasmids
    • Dai, Q, Restrepo, BI, Porcella, SF, Raffel, SJ, et al. Antigenic variation by Borrelia hermsii occurs through recombination between extragenic repetitive elements on linear plasmids. Mol Microbiol 2006; 60:1329-1343.
    • (2006) Mol Microbiol , vol.60 , pp. 1329-1343
    • Dai, Q.1    Restrepo, B.I.2    Porcella, S.F.3    Raffel, S.J.4
  • 15
    • 4544348356 scopus 로고    scopus 로고
    • Comparison of disseminated and nondisseminated strains of Borrelia burgdorferi sensu stricto in mice naturally infected by tick bite
    • Dolan, MC, Piesman, J, Schneider, BS, Schriefer, M, et al. Comparison of disseminated and nondisseminated strains of Borrelia burgdorferi sensu stricto in mice naturally infected by tick bite. Infect Immun 2004; 72:5262-5266.
    • (2004) Infect Immun , vol.72 , pp. 5262-5266
    • Dolan, M.C.1    Piesman, J.2    Schneider, B.S.3    Schriefer, M.4
  • 16
    • 0030060912 scopus 로고    scopus 로고
    • Conversion of a linear to a circular plasmid in the relapsing fever agent Borrelia hermsii
    • Ferdows, MS, Serwer, P, Griess, GA, Norris, SJ, et al. Conversion of a linear to a circular plasmid in the relapsing fever agent Borrelia hermsii. J Bacteriol 1996; 178:793-800.
    • (1996) J Bacteriol , vol.178 , pp. 793-800
    • Ferdows, M.S.1    Serwer, P.2    Griess, G.A.3    Norris, S.J.4
  • 17
    • 0031470826 scopus 로고    scopus 로고
    • Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi
    • Fraser, CM, Casjens, S, Huang, WM, Sutton, GG, et al. Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature 1997; 390:580-586.
    • (1997) Nature , vol.390 , pp. 580-586
    • Fraser, C.M.1    Casjens, S.2    Huang, W.M.3    Sutton, G.G.4
  • 18
    • 2642612784 scopus 로고    scopus 로고
    • Population structure of the relapsing fever spirochete Borrelia hermsii as indicated by polymorphism of two multigene families that encode immunogenic outer surface lipoproteins
    • Hinnebusch, BJ, Barbour, AG, Restrepo, BI, Schwan, TG. Population structure of the relapsing fever spirochete Borrelia hermsii as indicated by polymorphism of two multigene families that encode immunogenic outer surface lipoproteins. Infect Immun 1998; 66:432-440.
    • (1998) Infect Immun , vol.66 , pp. 432-440
    • Hinnebusch, B.J.1    Barbour, A.G.2    Restrepo, B.I.3    Schwan, T.G.4
  • 19
    • 42949116992 scopus 로고    scopus 로고
    • Identification of an anti-parallel coiled-coil/loop domain required for ligand binding by the Borrelia hermsii FhbA protein: Additional evidence for the role of FhbA in the host-pathogen interaction
    • Hovis, KM, Freedman, JC, Zhang, H, Forbes, JL, et al. Identification of an anti-parallel coiled-coil/loop domain required for ligand binding by the Borrelia hermsii FhbA protein: additional evidence for the role of FhbA in the host-pathogen interaction. Infect Immun 2008; 76:2113-2122.
    • (2008) Infect Immun , vol.76 , pp. 2113-2122
    • Hovis, K.M.1    Freedman, J.C.2    Zhang, H.3    Forbes, J.L.4
  • 20
    • 1942508082 scopus 로고    scopus 로고
    • Identification and characterization of a linear-plasmid-encoded Factor H-binding protein (FhbA) of the relapsing fever spirochete Borrelia hermsii
    • Hovis, KM, McDowell, JV, Griffin, L, Marconi, RT. Identification and characterization of a linear-plasmid-encoded Factor H-binding protein (FhbA) of the relapsing fever spirochete Borrelia hermsii. J Bacteriol 2004; 186:2612-2618.
    • (2004) J Bacteriol , vol.186 , pp. 2612-2618
    • Hovis, K.M.1    McDowell, J.V.2    Griffin, L.3    Marconi, R.T.4
  • 21
    • 33746585279 scopus 로고    scopus 로고
    • Immunological and molecular analyses of the Borrelia hermsii factor H and factor-H like protein 1 binding protein, FhbA: Demonstration of its utility as a diagnostic marker and epidemiological tool for tick-borne relapsing fever
    • Hovis, KM, Schriefer, ME, Bahlani, S, Marconi, RT. Immunological and molecular analyses of the Borrelia hermsii factor H and factor-H like protein 1 binding protein, FhbA: demonstration of its utility as a diagnostic marker and epidemiological tool for tick-borne relapsing fever. Infect Immun 2006;74:4519-4529.
    • (2006) Infect Immun , vol.74 , pp. 4519-4529
    • Hovis, K.M.1    Schriefer, M.E.2    Bahlani, S.3    Marconi, R.T.4
  • 22
    • 0021748707 scopus 로고
    • Infection of Syrian hamsters with Lyme disease spirochetes
    • Johnson, RC, Marek, N, Kodner, C. Infection of Syrian hamsters with Lyme disease spirochetes. J Clin Microbiol 1984; 20:1099-1101.
    • (1984) J Clin Microbiol , vol.20 , pp. 1099-1101
    • Johnson, R.C.1    Marek, N.2    Kodner, C.3
  • 23
    • 0015245768 scopus 로고
    • Cultivation of Borrelia hermsi
    • Kelly, R. Cultivation of Borrelia hermsi. Science 1971; 173:443-444.
    • (1971) Science , vol.173 , pp. 443-444
    • Kelly, R.1
  • 24
    • 0025002956 scopus 로고
    • Juxtaposition of expressed variable antigen genes with a conserved telomere in the bacterium Borrelia hermsii
    • Kitten, T, Barbour, AG. Juxtaposition of expressed variable antigen genes with a conserved telomere in the bacterium Borrelia hermsii. Proc Natl Acad Sci U S A 1990; 87:6077-6081.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 6077-6081
    • Kitten, T.1    Barbour, A.G.2
  • 25
    • 0035168567 scopus 로고    scopus 로고
    • Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1
    • Labandeira-Rey, M, Skare, JT. Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1. Infect Immun 2001; 69:446-455.
    • (2001) Infect Immun , vol.69 , pp. 446-455
    • Labandeira-Rey, M.1    Skare, J.T.2
  • 26
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 27
    • 0025116602 scopus 로고
    • Attenuation of Borrelia anserina by serial passage in liquid medium
    • Levine, JF, Dykstra, MJ, Nicholson, WL, Walker RL, et al. Attenuation of Borrelia anserina by serial passage in liquid medium. Res Vet Sci 1990; 48:64-69.
    • (1990) Res Vet Sci , vol.48 , pp. 64-69
    • Levine, J.F.1    Dykstra, M.J.2    Nicholson, W.L.3    Walker, R.L.4
  • 29
    • 0035049841 scopus 로고    scopus 로고
    • Isolation of Borrelia burgdorferi sensu lato from blood of patients with erythema migrans
    • Maraspin, V, Ruzic-Sabljic, E, Cimperman, J, Lotric-Furlan, S, et al. Isolation of Borrelia burgdorferi sensu lato from blood of patients with erythema migrans. Infection 2001; 29:65-70.
    • (2001) Infection , vol.29 , pp. 65-70
    • Maraspin, V.1    Ruzic-Sabljic, E.2    Cimperman, J.3    Lotric-Furlan, S.4
  • 30
    • 0029057891 scopus 로고
    • High- and low-infectivity phenotypes of clonal populations of in vitro-cultured Borrelia burgdorferi
    • Norris, SJ, Howell, JK, Garza, SA, Ferdows, MS, et al. High- and low-infectivity phenotypes of clonal populations of in vitro-cultured Borrelia burgdorferi. Infect Immun 1995; 63:2206-2212.
    • (1995) Infect Immun , vol.63 , pp. 2206-2212
    • Norris, S.J.1    Howell, J.K.2    Garza, S.A.3    Ferdows, M.S.4
  • 31
    • 0015981363 scopus 로고
    • Lipid catabolism of relapsing fever borreliae
    • Pickett, J, Kelly, R. Lipid catabolism of relapsing fever borreliae. Infect Immun 1974; 9:279-285.
    • (1974) Infect Immun , vol.9 , pp. 279-285
    • Pickett, J.1    Kelly, R.2
  • 32
    • 0022430232 scopus 로고
    • Transposition of structural genes to an expression sequence on a linear plasmid causes antigenic variation in the bacterium Borrelia hermsii
    • Plasterk, RHA, Simon, MI, Barbour, AG. Transposition of structural genes to an expression sequence on a linear plasmid causes antigenic variation in the bacterium Borrelia hermsii. Nature 1985; 318:257-263.
    • (1985) Nature , vol.318 , pp. 257-263
    • Plasterk, R.H.A.1    Simon, M.I.2    Barbour, A.G.3
  • 33
    • 25444515681 scopus 로고    scopus 로고
    • Variable tick protein in two genomic groups of the relapsing fever spirochete Borrelia hermsii in western North America
    • Porcella, SF, Raffel, SJ, Anderson Jr., DE, Gilk, SD, et al. Variable tick protein in two genomic groups of the relapsing fever spirochete Borrelia hermsii in western North America. Infect Immun 2005; 73:6647-6658.
    • (2005) Infect Immun , vol.73 , pp. 6647-6658
    • Porcella, S.F.1    Raffel, S.J.2    Anderson Jr., D.E.3    Gilk, S.D.4
  • 34
    • 0038687785 scopus 로고    scopus 로고
    • A plasmid-encoded nicotinamidase (PncA) is essential for infectivity of Borrelia burgdorferi in a mammalian host
    • Purser, JE, Lawrenz, MB, Caimano, MJ, Howell, JK, et al. A plasmid-encoded nicotinamidase (PncA) is essential for infectivity of Borrelia burgdorferi in a mammalian host. Mol Microbiol 2003; 48:753-764.
    • (2003) Mol Microbiol , vol.48 , pp. 753-764
    • Purser, J.E.1    Lawrenz, M.B.2    Caimano, M.J.3    Howell, J.K.4
  • 35
    • 0034610332 scopus 로고    scopus 로고
    • Correlation between plasmid content and infectivity in Borrelia burgdorferi
    • Purser, JE, Norris, SJ. Correlation between plasmid content and infectivity in Borrelia burgdorferi. Proc Natl Acad Sci U S A 2000; 97:13865-13870.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 13865-13870
    • Purser, J.E.1    Norris, S.J.2
  • 36
    • 0037315021 scopus 로고    scopus 로고
    • Glycerol-3-phosphate acquisition in spirochetes: Distribution and biological activity of glycerophosphodiester phosphodiesterase (GlpQ) among Borrelia spirochetes
    • Schwan, TG, Battisti, JM, Porcella, SF, Raffel, SJ, et al. Glycerol-3-phosphate acquisition in spirochetes: distribution and biological activity of glycerophosphodiester phosphodiesterase (GlpQ) among Borrelia spirochetes. J Bacteriol 2003; 185:1346-1356.
    • (2003) J Bacteriol , vol.185 , pp. 1346-1356
    • Schwan, T.G.1    Battisti, J.M.2    Porcella, S.F.3    Raffel, S.J.4
  • 37
    • 0023753146 scopus 로고
    • Changes in infectivity and plasmid profile of the Lyme disease spirochete, Borrelia burgdorferi, as a result of in vitro cultivation
    • Schwan, TG, Burgdorfer, W, Garon, CF. Changes in infectivity and plasmid profile of the Lyme disease spirochete, Borrelia burgdorferi, as a result of in vitro cultivation. Infect Immun 1988; 56:1831-1836.
    • (1988) Infect Immun , vol.56 , pp. 1831-1836
    • Schwan, T.G.1    Burgdorfer, W.2    Garon, C.F.3
  • 38
    • 0032546854 scopus 로고    scopus 로고
    • Bloodstream- versus tick-associated variants of a relapsing fever bacterium
    • Schwan, TG, Hinnebusch, BJ. Bloodstream- versus tick-associated variants of a relapsing fever bacterium. Science 1998; 280:1938-1940.
    • (1998) Science , vol.280 , pp. 1938-1940
    • Schwan, T.G.1    Hinnebusch, B.J.2
  • 39
    • 0024434520 scopus 로고
    • Antibody response in white-footed mice (Peromyscus leucopus) experimentally infected with the Lyme disease spirochete (Borrelia burgdorferi)
    • Schwan, TG, Kime, KK, Schrumpf, ME, Coe, JE, et al. Antibody response in white-footed mice (Peromyscus leucopus) experimentally infected with the Lyme disease spirochete (Borrelia burgdorferi). Infect Immun 1989; 57:3445-3451.
    • (1989) Infect Immun , vol.57 , pp. 3445-3451
    • Schwan, T.G.1    Kime, K.K.2    Schrumpf, M.E.3    Coe, J.E.4
  • 40
    • 23744496765 scopus 로고    scopus 로고
    • Phylogenetic analysis of the spirochetes Borrelia parkeri and Borrelia turicatae and the potential for tick-borne relapsing fever in Florida
    • Schwan, TG, Raffel, SJ, Schrumpf, ME, Policastro, PF, et al. Phylogenetic analysis of the spirochetes Borrelia parkeri and Borrelia turicatae and the potential for tick-borne relapsing fever in Florida. J Clin Microbiol 2005; 43:3851-3859.
    • (2005) J Clin Microbiol , vol.43 , pp. 3851-3859
    • Schwan, T.G.1    Raffel, S.J.2    Schrumpf, M.E.3    Policastro, P.F.4
  • 42
    • 0024992289 scopus 로고
    • Analysis of supercoiled circular plasmids in infectious and non-infectious Borrelia burgdorferi
    • Simpson, WJ, Garon, CF, Schwan, TG. Analysis of supercoiled circular plasmids in infectious and non-infectious Borrelia burgdorferi. Microb Pathog 1990; 8:109-118.
    • (1990) Microb Pathog , vol.8 , pp. 109-118
    • Simpson, W.J.1    Garon, C.F.2    Schwan, T.G.3
  • 43
    • 0016700864 scopus 로고
    • Detection of specific sequences among DNA fragments separated by gel electrophoresis
    • Southern, EM. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol 1975; 98:503-517.
    • (1975) J Mol Biol , vol.98 , pp. 503-517
    • Southern, E.M.1
  • 45
    • 0033919431 scopus 로고    scopus 로고
    • The relapsing fever spirochete Borrelia hermsii contains multiple, antigen-encoding circular plasmids that are homologous to the cp32 plasmids of Lyme disease spirochetes
    • Stevenson, B, Porcella, SF, Oie, KL, Fitzpatrick, CA, et al. The relapsing fever spirochete Borrelia hermsii contains multiple, antigen-encoding circular plasmids that are homologous to the cp32 plasmids of Lyme disease spirochetes. Infect Immun 2000; 68:3900-3908.
    • (2000) Infect Immun , vol.68 , pp. 3900-3908
    • Stevenson, B.1    Porcella, S.F.2    Oie, K.L.3    Fitzpatrick, C.A.4
  • 46
    • 0016280645 scopus 로고
    • Biology of Borrelia hermsii in Kelly medium
    • Stoenner, HG. Biology of Borrelia hermsii in Kelly medium. Appl Microbiol 1974; 28:540-543.
    • (1974) Appl Microbiol , vol.28 , pp. 540-543
    • Stoenner, H.G.1
  • 47
    • 0020461166 scopus 로고
    • Antigenic variation of Borrelia hermsii
    • Stoenner, HG, Dodd, T, Larsen, C. Antigenic variation of Borrelia hermsii. J Exp Med 1982; 156:1297-1311.
    • (1982) J Exp Med , vol.156 , pp. 1297-1311
    • Stoenner, H.G.1    Dodd, T.2    Larsen, C.3
  • 49
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin, H, Staehelin, T, Gordon, J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A 1979; 76:4350-4354.
    • (1979) Proc Natl Acad Sci U S A , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 50
    • 0034967970 scopus 로고    scopus 로고
    • Impact of genotype variation of Borrelia burgdorferi sensu stricto on kinetics of dissemination and severity of disease in C3H/HeJ mice
    • Wang, G, Ojaimi, C, Iver, R, Saksenberg, V, et al. Impact of genotype variation of Borrelia burgdorferi sensu stricto on kinetics of dissemination and severity of disease in C3H/HeJ mice. Infect Immun 2001; 69:4303-4312.
    • (2001) Infect Immun , vol.69 , pp. 4303-4312
    • Wang, G.1    Ojaimi, C.2    Iver, R.3    Saksenberg, V.4
  • 51
    • 0034002185 scopus 로고    scopus 로고
    • Comparison of the yields of blood cultures using serum or plasma from patients with early Lyme disease
    • Wormser, GP, Bittker, S, Cooper, D, Nowakowski, J, et al. Comparison of the yields of blood cultures using serum or plasma from patients with early Lyme disease. J Clin Microbiol 2000; 38:1648-1650.
    • (2000) J Clin Microbiol , vol.38 , pp. 1648-1650
    • Wormser, G.P.1    Bittker, S.2    Cooper, D.3    Nowakowski, J.4
  • 52
    • 0035297318 scopus 로고    scopus 로고
    • An analysis of spirochete load, strain, and pathology in a model of tick-transmitted Lyme borreliosis
    • Zeidner, NS, Schneider, BS, Dolan, MC, Piesman, J. An analysis of spirochete load, strain, and pathology in a model of tick-transmitted Lyme borreliosis. Vector Borne Zoonotic Dis 2001; 1:35-44.
    • (2001) Vector Borne Zoonotic Dis , vol.1 , pp. 35-44
    • Zeidner, N.S.1    Schneider, B.S.2    Dolan, M.C.3    Piesman, J.4


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