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Volumn 111, Issue 12, 2014, Pages 2123-2134

Coated zinc oxide improves intestinal immunity function and regulates microbiota composition in weaned piglets

Author keywords

Coated zinc oxide; Diarrhoea; Intestinal immunity; Microbiota composition

Indexed keywords

IMMUNOGLOBULIN A; INTERLEUKIN 10; OCCLUDIN; PROTEIN ZO1; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1; ZINC OXIDE; INTERLEUKIN 6; SECRETORY IMMUNOGLOBULIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84901258326     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114514000300     Document Type: Article
Times cited : (100)

References (53)
  • 1
    • 0344662162 scopus 로고    scopus 로고
    • Response of early-weaned pigs to an enterotoxigenic Escherichia coli (K88) challenge when fed diets containing spraydried porcine plasma or pea protein isolate plus egg yolk antibody, zinc oxide, fumaric acid, or antibiotic
    • Owusu-Asiedu A, Nyachoti C & Marquardt R (2003) Response of early-weaned pigs to an enterotoxigenic Escherichia coli (K88) challenge when fed diets containing spraydried porcine plasma or pea protein isolate plus egg yolk antibody, zinc oxide, fumaric acid, or antibiotic. J Anim Sci 81, 1790-1798.
    • (2003) J Anim Sci , vol.81 , pp. 1790-1798
    • Owusu-Asiedu, A.1    Nyachoti, C.2    Marquardt, R.3
  • 2
    • 33846235112 scopus 로고    scopus 로고
    • Stress signaling pathways activated by weaning mediate intestinal dysfunction in the pig
    • Moeser AJ, Klok CV, Ryan KA, et al. (2007) Stress signaling pathways activated by weaning mediate intestinal dysfunction in the pig. Am J Physiol Gastrointest Liver Physiol 292, G173-G181.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Moeser, A.J.1    Klok, C.V.2    Ryan, K.A.3
  • 3
    • 0025176439 scopus 로고
    • The effects of postweaning stressors on pig weight change, blood, liver and digestive tract characteristics
    • Funderburke D & Seerley R (1990) The effects of postweaning stressors on pig weight change, blood, liver and digestive tract characteristics. J Anim Sci 68, 155-162.
    • (1990) J Anim Sci , vol.68 , pp. 155-162
    • Funderburke, D.1    Seerley, R.2
  • 4
    • 0033124736 scopus 로고    scopus 로고
    • Early-and traditionally weaned nursery pigs benefit from phase-feeding pharmacological concentrations of zinc oxide: Effect on metallothionein and mineral concentrations
    • Carlson M, Hill G & Link J (1999) Early-and traditionally weaned nursery pigs benefit from phase-feeding pharmacological concentrations of zinc oxide: effect on metallothionein and mineral concentrations. J Anim Sci 77, 1199-1207.
    • (1999) J Anim Sci , vol.77 , pp. 1199-1207
    • Carlson, M.1    Hill, G.2    Link, J.3
  • 5
    • 0035318517 scopus 로고    scopus 로고
    • Effect of pharmacological concentrations of zinc oxide with or without the inclusion of an antibacterial agent on nursery pig performance
    • Hill G, Mahan D, Carter S, et al. (2001) Effect of pharmacological concentrations of zinc oxide with or without the inclusion of an antibacterial agent on nursery pig performance. J Anim Sci 79, 934-941.
    • (2001) J Anim Sci , vol.79 , pp. 934-941
    • Hill, G.1    Mahan, D.2    Carter, S.3
  • 6
    • 0027691872 scopus 로고
    • Growth and plasma zinc responses of young pigs fed pharmacologic levels of zinc
    • Hahn JD & Baker DH (1993) Growth and plasma zinc responses of young pigs fed pharmacologic levels of zinc. J Anim Sci 71, 3020-3024.
    • (1993) J Anim Sci , vol.71 , pp. 3020-3024
    • Hahn, J.D.1    Baker, D.H.2
  • 7
    • 0344306527 scopus 로고    scopus 로고
    • Zinc oxide protects cultured enterocytes from the damage induced by Escherichia coli
    • Roselli M, Finamore A, Garaguso I, et al. (2003) Zinc oxide protects cultured enterocytes from the damage induced by Escherichia coli. J Nutr 133, 4077-4082.
    • (2003) J Nutr , vol.133 , pp. 4077-4082
    • Roselli, M.1    Finamore, A.2    Garaguso, I.3
  • 8
    • 84881468893 scopus 로고    scopus 로고
    • Diosmectite-zinc oxide composite improves intestinal barrier function, modulates expression of pro-inflammatory cytokines and tight junction protein in early weaned pigs
    • Hu C, Song J, Li Y, et al. (2013) Diosmectite-zinc oxide composite improves intestinal barrier function, modulates expression of pro-inflammatory cytokines and tight junction protein in early weaned pigs. Br J Nutr 110, 681-688.
    • (2013) Br J Nutr , vol.110 , pp. 681-688
    • Hu, C.1    Song, J.2    Li, Y.3
  • 9
    • 84876344086 scopus 로고    scopus 로고
    • Effects of zinc oxide supported on zeolite on growth performance, intestinal microflora and permeability, and cytokines expression of weaned pigs
    • Hu C, Xiao K, Song J, et al. (2013) Effects of zinc oxide supported on zeolite on growth performance, intestinal microflora and permeability, and cytokines expression of weaned pigs. Anim Feed Sci Technol 181, 65-71.
    • (2013) Anim Feed Sci Technol , vol.181 , pp. 65-71
    • Hu, C.1    Xiao, K.2    Song, J.3
  • 10
    • 77953089407 scopus 로고    scopus 로고
    • Analysis of bacterial and fungal communities in Japanese-and Chinese-fermented soybean pastes using nested PCR-DGGE
    • Kim TW, Lee JH, Park MH, et al. (2010) Analysis of bacterial and fungal communities in Japanese-and Chinese-fermented soybean pastes using nested PCR-DGGE. Curr Microbiol 60, 315-320.
    • (2010) Curr Microbiol , vol.60 , pp. 315-320
    • Kim, T.W.1    Lee, J.H.2    Park, M.H.3
  • 11
    • 84858290120 scopus 로고    scopus 로고
    • Nutrition and pathology of weaner pigs: Nutritional strategies to support barrier function in the gastrointestinal tract
    • Kim JC, Hansen CF, Mullan BP, et al. (2012) Nutrition and pathology of weaner pigs: nutritional strategies to support barrier function in the gastrointestinal tract. Anim Feed Sci Technol 173, 3-16.
    • (2012) Anim Feed Sci Technol , vol.173 , pp. 3-16
    • Kim, J.C.1    Hansen, C.F.2    Mullan, B.P.3
  • 12
    • 0003498646 scopus 로고    scopus 로고
    • National Research Council 10th ed Washington, DC: National Academy Press
    • National Research Council (1998) Nutrient Requirements of Swine, 10th ed. Washington, DC: National Academy Press.
    • (1998) Nutrient Requirements of Swine
  • 13
    • 38149083542 scopus 로고    scopus 로고
    • Use of mannanoligosaccharides and zinc chelate as growth promoters and diarrhea preventative in weaning pigs: Effects on microbiota and gut function
    • Castillo M, Martin-Orue S, Taylor-Pickard J, et al. (2008) Use of mannanoligosaccharides and zinc chelate as growth promoters and diarrhea preventative in weaning pigs: effects on microbiota and gut function. J Anim Sci 86, 94-101.
    • (2008) J Anim Sci , vol.86 , pp. 94-101
    • Castillo, M.1    Martin-Orue, S.2    Taylor-Pickard, J.3
  • 14
    • 0003995078 scopus 로고
    • Association of Official Analytical Chemists 15th ed Washington, DC: AOAC
    • Association of Official Analytical Chemists (1990) Official Methods of Analysis, 15th ed. Washington, DC: AOAC.
    • (1990) Official Methods of Analysis
  • 15
    • 0038066208 scopus 로고    scopus 로고
    • Evaluation of QIAamp DNA Stool Mini Kit for ecological studies of gut microbiota
    • Li M, Gong J, Cottrill M, et al. (2003) Evaluation of QIAamp DNA Stool Mini Kit for ecological studies of gut microbiota. J Microbiol Methods 54, 13-20.
    • (2003) J Microbiol Methods , vol.54 , pp. 13-20
    • Li, M.1    Gong, J.2    Cottrill, M.3
  • 16
    • 67349283823 scopus 로고    scopus 로고
    • Dietary supplementation with Acanthopanax senticosus extract enhances gut health in weanling piglets
    • Fang J, Yan F, Kong X, et al. (2009) Dietary supplementation with Acanthopanax senticosus extract enhances gut health in weanling piglets. Livest Sci 123, 268-275.
    • (2009) Livest Sci , vol.123 , pp. 268-275
    • Fang, J.1    Yan, F.2    Kong, X.3
  • 17
    • 34547929063 scopus 로고    scopus 로고
    • DGGE and 16S rDNA sequencing analysis of bacterial communities in colon content and feces of pigs fed whole crop rice
    • Wang HF, Zhu WY, Yao W, et al. (2007) DGGE and 16S rDNA sequencing analysis of bacterial communities in colon content and feces of pigs fed whole crop rice. Anaerobe 13, 127-133.
    • (2007) Anaerobe , vol.13 , pp. 127-133
    • Wang, H.F.1    Zhu, W.Y.2    Yao, W.3
  • 18
    • 79957546509 scopus 로고    scopus 로고
    • Effects of different dietary protein sources on cecal microflora in rats
    • Qi H, Xiang Z, Han G, et al. (2011) Effects of different dietary protein sources on cecal microflora in rats. Afr J Biotechnol 10, 3704-3708
    • (2011) Afr J Biotechnol , vol.10 , pp. 3704-3708
    • Qi, H.1    Xiang, Z.2    Han, G.3
  • 19
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 22DDCT method
    • Livak KJ & Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 22DDCT method. Methods 25, 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 20
    • 22144470189 scopus 로고    scopus 로고
    • Assessment of soil microbial community structure by use of taxonspecific quantitative PCR assays
    • Fierer N, Jackson JA, Vilgalys R, et al. (2005) Assessment of soil microbial community structure by use of taxonspecific quantitative PCR assays. Appl Environ Microbiol 71, 4117-4120.
    • (2005) Appl Environ Microbiol , vol.71 , pp. 4117-4120
    • Fierer, N.1    Jackson, J.A.2    Vilgalys, R.3
  • 21
    • 0036654532 scopus 로고    scopus 로고
    • Effect of feeding organic and inorganic sources of additional zinc on growth performance and zinc balance in nursery pigs
    • Case C & Carlson M (2002) Effect of feeding organic and inorganic sources of additional zinc on growth performance and zinc balance in nursery pigs. J Anim Sci 80, 1917-1924.
    • (2002) J Anim Sci , vol.80 , pp. 1917-1924
    • Case, C.1    Carlson, M.2
  • 22
    • 33645212502 scopus 로고    scopus 로고
    • Quantification of total bacteria, enterobacteria and lactobacilli populations in pig digesta by real-time PCR
    • Castillo M, Mart́n-Orúe SM, Manzanilla EG, et al. (2006) Quantification of total bacteria, enterobacteria and lactobacilli populations in pig digesta by real-time PCR. Vet Microbiol 114, 165-170.
    • (2006) Vet Microbiol , vol.114 , pp. 165-170
    • Castillo, M.1    Martn-Orue, S.M.2    Manzanilla, E.G.3
  • 23
    • 0030183549 scopus 로고    scopus 로고
    • Zinc concentration in tissues and performance of weanling pigs fed pharmacological levels of zinc from ZnO, Zn-methionine, Zn-lysine, or ZnSO4
    • Schell T & Kornegay E (1996) Zinc concentration in tissues and performance of weanling pigs fed pharmacological levels of zinc from ZnO, Zn-methionine, Zn-lysine, or ZnSO4. J Anim Sci 74, 1584-1593.
    • (1996) J Anim Sci , vol.74 , pp. 1584-1593
    • Schell, T.1    Kornegay, E.2
  • 25
    • 34548009613 scopus 로고    scopus 로고
    • Dietary specific antibodies in spray-dried immune plasma prevent enterotoxigenic F4 (ETEC) post weaning diarrhoea in piglets
    • Niewold TA, van Dijk AJ, Geenen PL, et al. (2007) Dietary specific antibodies in spray-dried immune plasma prevent enterotoxigenic F4 (ETEC) post weaning diarrhoea in piglets. Vet Microbiol 124, 3-4.
    • (2007) Vet Microbiol , vol.124 , pp. 3-4
    • Niewold, T.A.1    Van Dijk, A.J.2    Geenen, P.L.3
  • 26
    • 33847134446 scopus 로고    scopus 로고
    • Main intestinal markers associated with the changes in gut architecture and function in piglets after weaning
    • Montagne L, Boudry G, Favier C, et al. (2007) Main intestinal markers associated with the changes in gut architecture and function in piglets after weaning. Br J Nutr 97, 45-57.
    • (2007) Br J Nutr , vol.97 , pp. 45-57
    • Montagne, L.1    Boudry, G.2    Favier, C.3
  • 27
    • 0035650367 scopus 로고    scopus 로고
    • Small intestinal morphology and bacterial populations in ileal digesta and feces of newly weaned pigs receiving a high dietary level of zinc oxide
    • Li B, Van Kessel A, Caine W, et al. (2001) Small intestinal morphology and bacterial populations in ileal digesta and feces of newly weaned pigs receiving a high dietary level of zinc oxide. Can J Anim Sci 81, 511-516.
    • (2001) Can J Anim Sci , vol.81 , pp. 511-516
    • Li, B.1    Van Kessel, A.2    Caine, W.3
  • 28
    • 33745644490 scopus 로고    scopus 로고
    • Dietary supplementation with zinc oxide increases IGF-I and IGF-I receptor gene expression in the small intestine of weanling piglets
    • Li X, Yin J, Li D, et al. (2006) Dietary supplementation with zinc oxide increases IGF-I and IGF-I receptor gene expression in the small intestine of weanling piglets. J Nutr 136, 1786-1791.
    • (2006) J Nutr , vol.136 , pp. 1786-1791
    • Li, X.1    Yin, J.2    Li, D.3
  • 29
    • 0000785742 scopus 로고    scopus 로고
    • Factors influencing the structure and function of the small intestine in the weaned pig: A review
    • Pluske JR, Hampson DJ & Williams IH (1997) Factors influencing the structure and function of the small intestine in the weaned pig: a review. Livest Prod Sci 51, 215-236.
    • (1997) Livest Prod Sci , vol.51 , pp. 215-236
    • Pluske, J.R.1    Hampson, D.J.2    Williams, I.H.3
  • 30
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: Biological actions
    • Jones JI & Clemmons DR (1995) Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 16, 3-34.
    • (1995) Endocr Rev , vol.16 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 31
    • 0032871231 scopus 로고    scopus 로고
    • Oral IGF-I enhances nutrient and electrolyte absorption in neonatal piglet intestine
    • Alexander AN & Carey HV (1999) Oral IGF-I enhances nutrient and electrolyte absorption in neonatal piglet intestine. Am J Physiol 277, G619-G625.
    • (1999) Am J Physiol , vol.277
    • Alexander, A.N.1    Carey, H.V.2
  • 32
    • 79955665201 scopus 로고    scopus 로고
    • Intestinal barrier function and absorption in pigs after weaning: A review
    • Wijtten PJ, Meulen Jvd & Verstegen MW (2011) Intestinal barrier function and absorption in pigs after weaning: a review. Br J Nutr 105, 967-981.
    • (2011) Br J Nutr , vol.105 , pp. 967-981
    • Wijtten, P.J.1    Meulen, J.V.D.2    Verstegen, M.W.3
  • 34
    • 70350088307 scopus 로고    scopus 로고
    • Supplemental zinc reduced intestinal permeability by enhancing occludin and zonula occludens protein-1 (ZO-1) expression in weaning piglets
    • Zhang B & Guo Y (2009) Supplemental zinc reduced intestinal permeability by enhancing occludin and zonula occludens protein-1 (ZO-1) expression in weaning piglets. Br J Nutr 102, 687-693.
    • (2009) Br J Nutr , vol.102 , pp. 687-693
    • Zhang, B.1    Guo, Y.2
  • 35
    • 83655191565 scopus 로고    scopus 로고
    • Epithelial barrier: An interface for the cross-communication between gut flora and immune system
    • Goto Y & Kiyono H (2012) Epithelial barrier: an interface for the cross-communication between gut flora and immune system. Immunol Rev 245, 147-163.
    • (2012) Immunol Rev , vol.245 , pp. 147-163
    • Goto, Y.1    Kiyono, H.2
  • 36
    • 80054963764 scopus 로고    scopus 로고
    • Regulation of the polymeric immunoglobulin receptor and IgA transport: New advances in environmental factors that stimulate pIgR expression and its role in mucosal immunity
    • Johansen FE & Kaetzel CS (2011) Regulation of the polymeric immunoglobulin receptor and IgA transport: new advances in environmental factors that stimulate pIgR expression and its role in mucosal immunity. Mucosal Immunol 4, 598-602.
    • (2011) Mucosal Immunol , vol.4 , pp. 598-602
    • Johansen, F.E.1    Kaetzel, C.S.2
  • 37
    • 0033833633 scopus 로고    scopus 로고
    • Saccharomyces boulardii stimulates sIgA production and the phagocytic system of gnotobiotic mice
    • Rodrigues AC, Cara DC, Fretez SH, et al. (2000) Saccharomyces boulardii stimulates sIgA production and the phagocytic system of gnotobiotic mice. J Appl Microbiol 89, 404-414.
    • (2000) J Appl Microbiol , vol.89 , pp. 404-414
    • Rodrigues, A.C.1    Cara, D.C.2    Fretez, S.H.3
  • 38
    • 64349088288 scopus 로고    scopus 로고
    • Mucosal IgA increase in rats by continuous CLA feeding during suckling and early infancy
    • Pérez-Cano FJ, Raḿrez-Santana C, Molero-Lús M, et al. (2009) Mucosal IgA increase in rats by continuous CLA feeding during suckling and early infancy. J lipid Res 50, 467-476.
    • (2009) J Lipid Res , vol.50 , pp. 467-476
    • Perez-Cano, F.J.1    Ramrez-Santana, C.2    Molero-Lus, M.3
  • 39
    • 0027752694 scopus 로고
    • Influence of fatty acid absorption on bidirectional release of immunoglobulin A into intestinal lumen and intestinal lymph in rats
    • Imaeda H, Miura S, Serizawa H, et al. (1993) Influence of fatty acid absorption on bidirectional release of immunoglobulin A into intestinal lumen and intestinal lymph in rats. Immunol lett 38, 253-258.
    • (1993) Immunol Lett , vol.38 , pp. 253-258
    • Imaeda, H.1    Miura, S.2    Serizawa, H.3
  • 40
    • 78650816072 scopus 로고    scopus 로고
    • Effects of vitamin A deficiency on mucosal immunity and response to intestinal infection in rats
    • Yang Y, Yuan Y, Tao Y, et al. (2011) Effects of vitamin A deficiency on mucosal immunity and response to intestinal infection in rats. Nutrition 27, 227-232.
    • (2011) Nutrition , vol.27 , pp. 227-232
    • Yang, Y.1    Yuan, Y.2    Tao, Y.3
  • 41
    • 0027535483 scopus 로고
    • A trial of zinc supplementation in young rural Gambian children
    • Bates C, Evans P, Dardenne M, et al. (1993) A trial of zinc supplementation in young rural Gambian children. Br J Nutr 69, 243-255.
    • (1993) Br J Nutr , vol.69 , pp. 243-255
    • Bates, C.1    Evans, P.2    Dardenne, M.3
  • 42
    • 1642355858 scopus 로고    scopus 로고
    • Effect of zinc supplementation on immune and inflammatory responses in pediatric patients with shigellosis
    • Raqib R, Roy SK, Rahman MJ, et al. (2004) Effect of zinc supplementation on immune and inflammatory responses in pediatric patients with shigellosis. Am J Clin Nutr 79, 444-450.
    • (2004) Am J Clin Nutr , vol.79 , pp. 444-450
    • Raqib, R.1    Roy, S.K.2    Rahman, M.J.3
  • 43
    • 0034713266 scopus 로고    scopus 로고
    • Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
    • Borovikova LV, Ivanova S, Zhang M, et al. (2000) Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 405, 458-462.
    • (2000) Nature , vol.405 , pp. 458-462
    • Borovikova, L.V.1    Ivanova, S.2    Zhang, M.3
  • 44
    • 0036164902 scopus 로고    scopus 로고
    • Interleukin-10: A complex role in the pathogenesis of sepsis syndromes and its potential as an anti-inflammatory drug
    • Oberholzer A, Oberholzer C & Moldawer LL (2002) Interleukin-10: a complex role in the pathogenesis of sepsis syndromes and its potential as an anti-inflammatory drug. Crit Care Med 30, Suppl. 1, S58-S63.
    • (2002) Crit Care Med , vol.30 , Issue.SUPPL. 1
    • Oberholzer, A.1    Oberholzer, C.2    Moldawer, L.L.3
  • 45
    • 80051928334 scopus 로고    scopus 로고
    • Inflammatory response of porcine epithelial IPEC J2 cells to enterotoxigenic E. Coli infection is modulated by zinc supplementation
    • Sargeant HR, Miller HM & Shaw MA (2011) Inflammatory response of porcine epithelial IPEC J2 cells to enterotoxigenic E. coli infection is modulated by zinc supplementation. Mol Immunol 48, 2113-2121.
    • (2011) Mol Immunol , vol.48 , pp. 2113-2121
    • Sargeant, H.R.1    Miller, H.M.2    Shaw, M.A.3
  • 46
    • 80054095794 scopus 로고    scopus 로고
    • Intestinal microecology in health and wellness
    • Floch MH (2011) Intestinal microecology in health and wellness. J Clin Gastroenterol 45, S108-S110.
    • (2011) J Clin Gastroenterol , vol.45
    • Floch, M.H.1
  • 47
    • 42149140186 scopus 로고    scopus 로고
    • Evaluation of alternatives to antibiotics using an Escherichia coli K88 + model of piglet diarrhea: Effects on gut microbial ecology
    • Bhandari S, Xu B, Nyachoti C, et al. (2008) Evaluation of alternatives to antibiotics using an Escherichia coli K88 + model of piglet diarrhea: effects on gut microbial ecology. J Anim Sci 86, 836-847.
    • (2008) J Anim Sci , vol.86 , pp. 836-847
    • Bhandari, S.1    Xu, B.2    Nyachoti, C.3
  • 48
    • 84856232056 scopus 로고    scopus 로고
    • Effect of bamboo vinegar as an antibiotic alternative on growth performance and fecal bacterial communities of weaned piglets
    • Wang HF, Wang JL, Wang C, et al. (2012) Effect of bamboo vinegar as an antibiotic alternative on growth performance and fecal bacterial communities of weaned piglets. Livest Sci 144, 173-180.
    • (2012) Livest Sci , vol.144 , pp. 173-180
    • Wang, H.F.1    Wang, J.L.2    Wang, C.3
  • 49
    • 58149327025 scopus 로고    scopus 로고
    • Dietary protein concentration affects intestinal microbiota of adult cats: A study using DGGE and qPCR to evaluate differences in microbial populations in the feline gastrointestinal tract
    • Lubbs D, Vester B, Fastinger N, et al. (2009) Dietary protein concentration affects intestinal microbiota of adult cats: a study using DGGE and qPCR to evaluate differences in microbial populations in the feline gastrointestinal tract. J Anim Physiol Anim Nutr 93, 113-121.
    • (2009) J Anim Physiol Anim Nutr , vol.93 , pp. 113-121
    • Lubbs, D.1    Vester, B.2    Fastinger, N.3
  • 50
    • 44449110607 scopus 로고    scopus 로고
    • Characterization of ileal bacterial microbiota in newly-weaned pigs in response to feeding lincomycin, organic acids or herbal extract
    • Gong J, Yu H, Liu T, et al. (2008) Characterization of ileal bacterial microbiota in newly-weaned pigs in response to feeding lincomycin, organic acids or herbal extract. Livest Sci 116, 318-322.
    • (2008) Livest Sci , vol.116 , pp. 318-322
    • Gong, J.1    Yu, H.2    Liu, T.3
  • 51
    • 0032061664 scopus 로고    scopus 로고
    • Dietary zinc oxide in weaned pigs-effects on performance, tissue concentrations, morphology, neutrophil functions and faecal microflora
    • Jensen-Waern M, Melin L, Lindberg R, et al. (1998) Dietary zinc oxide in weaned pigs-effects on performance, tissue concentrations, morphology, neutrophil functions and faecal microflora. Res Vet Sci 64, 225-231.
    • (1998) Res Vet Sci , vol.64 , pp. 225-231
    • Jensen-Waern, M.1    Melin, L.2    Lindberg, R.3
  • 52
    • 18444366772 scopus 로고    scopus 로고
    • Influence of dietary zinc oxide and copper sulfate on the gastrointestinal ecosystem in newly weaned piglets
    • Højberg O, Canibe N, Poulsen HD, et al. (2005) Influence of dietary zinc oxide and copper sulfate on the gastrointestinal ecosystem in newly weaned piglets. Appl Environ Microbiol 71, 2267-2277.
    • (2005) Appl Environ Microbiol , vol.71 , pp. 2267-2277
    • Højberg, O.1    Canibe, N.2    Poulsen, H.D.3
  • 53
    • 27744474716 scopus 로고    scopus 로고
    • Effects of zinc oxide and Enterococcus faecium SF68 dietary supplementation on the performance, intestinal microbiota and immune status of weaned piglets
    • BroomLJ, MillerHM, Kerr KG, et al. (2006) Effects of zinc oxide and Enterococcus faecium SF68 dietary supplementation on the performance, intestinal microbiota and immune status of weaned piglets. Res Vet Sci 80, 45-54.
    • (2006) Res Vet Sci , vol.80 , pp. 45-54
    • Broom, L.J.1    Miller, H.M.2    Kerr, K.G.3


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