Mucosal IgA increase in rats by continuous CLA feeding during suckling and early infancy

Journal of Lipid Research

Volumn 50, Issue 3, 2009, Pages 467-476

  Pérez Cano, Francisco J ^a   Ramírez Santana, Carolina ^a   Molero Luís, Marta ^a   Castell, Margarida ^a   Rivero, Montserrat ^b,c   Castellote, Cristina ^a   Franch, Àngels ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Scientific Park of Barcelona   (Spain)

^c CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

Author keywords

Conjugated linoleic acid; Gestation; Mucosal immunity

Indexed keywords

CONJUGATED LINOLEIC ACID; IMMUNOGLOBULIN A; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSFORMING GROWTH FACTOR BETA; CIS 9, TRANS 11 CONJUGATED LINOLEIC ACID; CIS-9, TRANS-11-CONJUGATED LINOLEIC ACID; EDIBLE OIL; SECRETORY IMMUNOGLOBULIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLON; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNOGLOBULIN PRODUCTION; IMMUNOMODULATION; INFANCY; MOLECULAR PROBE; MUCOSAL IMMUNITY; NEWBORN; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SMALL INTESTINE; SUCKLING; TISSUE LEVEL; WEANING; ANIMAL; FEMALE; GENETICS; HISTOLOGY; IMMUNOLOGY; METABOLISM; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; ANIMALS, SUCKLING; COLON; DIETARY FATS, UNSATURATED; DIETARY SUPPLEMENTS; FEMALE; GENE EXPRESSION; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A, SECRETORY; INTESTINE, SMALL; LINOLEIC ACIDS, CONJUGATED; PPAR GAMMA; PREGNANCY; RATS; RATS, WISTAR; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 64349088288     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M800356-JLR200     Document Type: Article

References (56)

1. Adkins, B., C. Leclerc, and S. Marshall-Clarke. 2004. Neonatal adaptive immunity comes of age. Nat. Rev. Immunol. 4: 553-564.
2. Marodi, L. 2006. Innate cellular immune responses in newborns. Clin. Immunol. 118: 137-144.
3. Charrier, E., R. Dardari, A. Michaud, P. Cordeiro, and M. Duval. 2007. Neonatal immunology and cord blood transplantation. Med. Sci. (Paris). 23: 975-979.
4. Pérez-Cano, F. J., C. Castellote, S. Marín-Gallén, À. Franch, and M. Castell. 2005. Neonatal immunoglobulin secretion and lymphocyte phenotype in rat small intestine lamina propria. Pediatr. Res. 58: 164-169.
5. Calder, P. C., and S. Kew. 2002. The immune system: a target for functional foods? Br. J. Nutr. 88 (Suppl 2): S165-S177.
6. Mowat, A. M. 2003. Anatomical basis of tolerance and immunity to intestinal antigens. Nat. Rev. Immunol. 3: 331-341.
7. Brandtzaeg, P., and F. E. Johansen. 2005. Mucosal B cells: phenotypic characteristics, transcriptional regulation, and homing properties. Immunol. Rev. 206: 32-63.
8. Fagarasan, S. 2008. Evolution, development, mechanism and function of IgA in the gut. Curr. Opin. Immunol. 20: 170-177.
9. Lönnerdal, B. 2003. Nutritional and physiologic significance of human milk proteins. Am. J. Clin. Nutr. 77: 1537S-1543S.
10. Pariza, M. W., Y. Park, and M. E. Cook. 2000. Mechanisms of action of conjugated linoleic acid: evidence and speculation. Proc. Soc. Exp. Biol. Med. 223: 8-13.
11. Hayashi, A. A., S. R. de Medeiros, M. H. Carvalho, and D. P. Lanna. 2007. Conjugated linoleic acid (CLA) effects on pups growth, milk composition and lipogenic enzymes in lactating rats. J. Dairy Res. 74: 160-166.
12. Luna, P., M. Juárez, and M. Ángel de la Fuente. 2007. Fatty acid and conjugated linoleic acid isomer profiles in human milk fat. Eur. J. Lipid Sci. Technol. 109: 1160-1166.
13. Visonneau, S., A. Cesano, S. A. Tepper, J. A. Scimeca, D. Santoli, and D. Kritchevsky. 1997. Conjugated linoleic acid suppresses the growth of human breast adenocarcinoma cells in SCID mice. Anticancer Res. 17: 969-973.
14. Ip, M. M., P. A. Masso-Welch, S. F. Shoemaker, W. K. Shea-Eaton, and C. Ip. 1999. Conjugated linoleic acid inhibits proliferation and induces apoptosis of normal rat mammary epithelial cells in primary culture. Exp. Cell Res. 250: 22-34.
15. Kelley, N. S., N. E. Hubbard, and K. L. Erickson. 2007. Conjugated linoleic acid isomers and cancer. J. Nutr. 137: 2599-2607.
16. Sugano, M., A. Tsujita, M. Yamasaki, M. Noguchi, and K. Yamada. 1998. Conjugated linoleic acid modulates tissue levels of chemical mediators and immunoglobulins in rats. Lipids. 33: 521-527.
17. O'Shea, M., J. Bassaganya-Riera, and I. C. Mohede. 2004. Immunomodulatory properties of conjugated linoleic acid. Am. J. Clin. Nutr. 79: 1199S-1206S.
18. Yamasaki, M., H. Chujo, A. Hirao, N. Koyanagi, T. Okamoto, N. Tojo, A. Oishi, T. Iwata, Y. Yamauchi-Sato, T. Yamamoto, et al. 2003. Immunoglobulin and cytokine production from spleen lymphocytes is modulated in C57BL/6J mice by dietary cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid. J. Nutr. 133: 784-788.
19. Turpeinen, A. M., E. von Willebrand, I. Salminen, J. Linden, S. Basu, and D. Rai. 2006. Effects of cis-9,trans-11 CLA in rats at intake levels reported for breast-fed infants. Lipids. 41: 669-677.
20. Butz, D. E., G. Li, S. M. Huebner, and M. E. Cook. 2007. A mechanistic approach to understanding conjugated linoleic acid's role in inflammation using murine models of rheumatoid arthritis. Am. J. Physiol. Regul. Integr. Comp. Physiol. 293: R669-R676.
21. Turpeinen, A. M., N. Ylonen, E. von Willebrand, S. Basu, and A. Aro. 2008. Immunological and metabolic effects of cis-9, trans-11-conjugated linoleic acid in subjects with birch pollen allergy. Br. J. Nutr. 100: 112-119.
22. Sanderson, I. R., and S. Naik. 2000. Dietary regulation of intestinal gene expression. Annu. Rev. Nutr. 20: 311-338.
23. Wallace, F. A., E. A. Miles, C. Evans, T. E. Stock, P. Yaqoob, and P. C. Calder. 2001. Dietary fatty acids influence the production of Th1-but not Th2-type cytokines. J. Leukoc. Biol. 69: 449-457.
24. Calder, P. C., and C. J. Field. 2002. Fatty acids, inflammation and immunity. In Nutrition and Immune Function. P. C. Calder, C. J. Field, and H. S. Gill, editors. CAB International, Southhampton, UK. 57-92.
25. Hwang, D. 2000. Fatty acids and immune responses-a new perspective in searching for clues to mechanism. Annu. Rev. Nutr. 20: 431-456.
26. Bassaganya-Riera, J., R. Hontecillas, and D. C. Beitz. 2002. Colonic anti-inflammatory mechanisms of conjugated linoleic acid. Clin. Nutr. 21: 451-459.
27. Schoonjans, K., G. Martin, B. Staels, and J. Auwerx. 1997. Peroxisome proliferator-activated receptors, orphans with ligands and functions. Curr. Opin. Lipidol. 8: 159-166.
28. Tontonoz, P., L. Nagy, J. G. Alvarez, V. A. Thomazy, and R. M. Evans. 1998. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 93: 241-252.
29. Bünger, M., G. J. Hooiveld, S. Kersten, and M. Muller. 2007. Exploration of PPAR functions by microarray technology A paradigm for nutrigenomics. Biochim. Biophys. Acta. 1771: 1046-1064.
30. Bassaganya-Riera, J., K. Reynolds, S. Martino-Catt, Y. Cui, L. Hennighausen, F. González, J. Rohrer, A. U. Benninghoff, and R. Hontecillas. 2004. Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease. Gastroenterology. 127: 777-791.
31. Bassaganya-Riera, J., and R. Hontecillas. 2006. CLA and n-3 PUFA differentially modulate clinical activity and colonic PPAR-responsive gene expression in a pig model of experimental IBD. Clin. Nutr. 25: 454-465.
32. Borsutzky, S., B. B. Cazac, J. Roes, and C. A. Guzman. 2004. TGF-beta receptor signaling is critical for mucosal IgA responses. J. Immunol. 173: 3305-3309.
33. Rodríguez-Palmero, M., À. Franch, M. Castell, C. Pelegrí, F. J. Pérez-Cano, C. Kleinschnitz, G. Stoll, T. Hünig, and C. Castellote. 2006. Effective treatment of adjuvant arthritis with a stimulatory CD28-specific monoclonal antibody. J. Rheumatol. 33: 110-118.
34. Pérez-Cano, F. J., À. Franch, C. Castellote, and M. Castell. 2003. Immunomodulatory action of spermine and spermidine on NR8383 macrophage line in various culture conditions. Cell. Immunol. 226: 86-94.
35. Perán, L., D. Camuesco, M. Comalada, A. Nieto, A. Concha, M. P. Díaz-Ropero, M. Olivares, J. Xaus, A. Zarzuelo, and J. Gálvez. 2005. Preventative effects of a probiotic, Lactobacillus salivarius ssp. Salivarius, in the TNBS model of rat colitis. World J. Gastroenterol. 11: 5185-5192.
36. Song, H. J., I. Grant, D. Rotondo, I. Mohede, N. Sattar, S. D. Heys, and K. W. Wahle. 2005. Effect of CLA supplementation on immune function in young healthy volunteers. Eur. J. Clin. Nutr. 59: 508-517.
37. Yamasaki, M., K. Kishihara, K. Mansho, Y. Ogino, M. Kasai, M. Sugano, H. Tachibana, and K. Yamada. 2000. Dietary conjugated linoleic acid increases immunoglobulin productivity of Sprague-Dawley rat spleen lymphocytes. Biosci. Biotechnol. Biochem. 64: 2159-2164.
38. Bontempo, V., D. Sciannimanico, G. Pastorelli, R. Rossi, F. Rosi, and C. Corino. 2004. Dietary conjugated linoleic acid positively affects immunologic variables in lactating sows and piglets. J. Nutr. 134: 817-824.
39. Cook, M. E. 2002. Conjugated linoleic acid's role in immunity and immune related disorders. Perspectives on Conjugated Linoleic Acid Research: Current Status and Future Directions, NIH, Bethesda, MD.
40. Hontecillas, R., M. J. Wannemeulher, D. R. Zimmerman, D. L. Hutto, J. H. Wilson, D. U. Ahn, and J. Bassaganya-Riera. 2002. Nutritional regulation of porcine bacterial-induced colitis by conjugated linoleic acid. J. Nutr. 132: 2019-2027.
41. Bassaganya-Riera, J., R. Hontecillas-Magarzo, K. Bregendahl, M. J. Wannemuehler, and D. R. Zimmerman. 2001. Effects of dietary conjugated linoleic acid in nursery pigs of dirty and clean environments on growth, empty body composition, and immune competence. J. Anim. Sci. 79: 714-721.
42. Cerutti, A. 2008. The regulation of IgA class switching. Nat. Rev. Immunol. 8: 421-434.
43. Kim, P. H., and M. F. Kagnoff. 1990. Effects of transforming growth factor beta-1 and interleukin-5 on IgA isotype switching at the clonal level. J. Immunol. 145: 3773-3778.
44. Tokuyama, H., and Y. Tokuyama. 1999. The regulatory effects of all-trans-retinoic acid on isotype switching: retinoic acid induces IgA switch rearrangement in cooperation with IL-5 and inhibits IgG1 switching. Cell. Immunol. 192: 41-47.
45. Braissant, O., F. Foufelle, C. Scotto, M. Dauca, and W. Wahli. 1996. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology. 137: 354-366.
46. Mansén, A., H. Guardiola-Díaz, J. Rafter, C. Branting, and J. A. Gustafsson. 1996. Expression of the peroxisome proliferator-activated receptor (PPAR) in the mouse colonic mucosa. Biochem. Biophys. Res. Commun. 222: 844-851.
47. Chawla, A., J. J. Repa, R. M. Evans, and D. J. Mangelsdorf. 2001. Nuclear receptors and lipid physiology: opening the X-files. Science. 294: 1866-1870.
48. Dubuquoy, L., C. Rousseaux, X. Thuru, L. Peyrin-Biroulet, O. Romano, P. Chavatte, M. Chamaillard, and P. Desreumaux. 2006. PPARgamma as a new therapeutic target in inflammatory bowel diseases. Gut. 55: 1341-1349.
49. Takamura, T., E. Nohara, Y. Nagai, and K. Kobayashi. 2001. Stagespecific effects of a thiazolidinedione on proliferation, differentiation and PPARgamma mRNA expression in 3T3-L1 adipocytes. Eur. J. Pharmacol. 422: 23-29.
50. Padilla, J., K. Kaur, S. G. Harris, and R. P. Phipps. 2000. PPARgamma-mediated regulation of normal and malignant B lineage cells. Ann. N. Y. Acad. Sci. 905: 97-109.
51. Nencioni, A., F. Grunebach, A. Zobywlaski, C. Denzlinger, W. Brugger, and P. Brossart. 2002. Dendritic cell immunogenicity is regulated by peroxisome proliferator-activated receptor gamma. J. Immunol. 169: 1228-1235.
52. Hontecillas, R., and J. Bassaganya-Riera. 2003. Differential requirements for proliferation of CD41 and gammadelta1 T cells to spirochetal antigens. Cell. Immunol. 224: 38-46.
53. Ponferrada, A., J. R. Caso, L. Alou, A. Colon, D. Sevillano, M. A. Moro, I. Lizasoain, P. Menchen, M. L. Gomez-Lus, P. Lorenzo, et al. 2007. The role of PPARgamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction. Gastroenterology. 132: 1791-1803.
54. Li, M., G. Pascual, and C. K. Glass. 2000. Peroxisome proliferatoractivated receptor gamma-dependent repression of the inducible nitric oxide synthase gene. Mol. Cell. Biol. 20: 4699-4707.
55. Kelly, D., J. I. Campbell, T. P. King, G. Grant, E. A. Jansson, A. G. Coutts, S. Pettersson, and S. Conway. 2004. Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclearcytoplasmic shuttling of PPAR-gamma and RelA. Nat. Immunol. 5: 104-112.
56. Dubuquoy, L., E. A. Jansson, S. Deeb, S. Rakotobe, M. Karoui, J. F. Colombel, J. Auwerx, S. Pettersson, and P. Desreumaux. 2003. Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis. Gastroenterology. 124: 1265-1276.