메뉴 건너뛰기




Volumn 8, Issue , 2014, Pages 10-15

Ribavirin: A drug active against many viruses with multiple effects on virus replication and propagation. Molecular basis of ribavirin resistance

Author keywords

[No Author keywords available]

Indexed keywords

AZACITIDINE; RIBAVIRIN; ANTIVIRUS AGENT;

EID: 84901253888     PISSN: 18796257     EISSN: 18796265     Source Type: Journal    
DOI: 10.1016/j.coviro.2014.04.011     Document Type: Review
Times cited : (100)

References (51)
  • 1
    • 1442285305 scopus 로고    scopus 로고
    • Management and prevention strategies for respiratory syncytial virus (RSV) bronchiolitis in infants and young children: A review of evidence-based practice interventions
    • A.C. Cooper, N.C. Banasiak, and P.J. Allen Management and prevention strategies for respiratory syncytial virus (RSV) bronchiolitis in infants and young children: a review of evidence-based practice interventions Pediatr Nurs 29 2003 452 456
    • (2003) Pediatr Nurs , vol.29 , pp. 452-456
    • Cooper, A.C.1    Banasiak, N.C.2    Allen, P.J.3
  • 2
    • 0022630892 scopus 로고
    • Lassa fever: Effective therapy with ribavirin
    • J.B. McCormick, I.J. King, P.A. Webb, C.L. Scribner, R.B. Craven, K.M. Johnson, L.H. Elliott, and R. Belmont-Williams Lassa fever. Effective therapy with ribavirin N Engl J Med 314 1986 20 26 (Pubitemid 16183064)
    • (1986) New England Journal of Medicine , vol.314 , Issue.1 , pp. 20-26
    • McCormick, J.B.1    King, I.J.2    Webb, P.A.3
  • 4
    • 0037302381 scopus 로고    scopus 로고
    • Therapeutic options for diseases due to potential viral agents of bioterrorism
    • M.S. Bronze, and R.A. Greenfield Therapeutic options for diseases due to potential viral agents of bioterrorism Curr Opin Investig Drugs 4 2003 172 178 (Pubitemid 36383013)
    • (2003) Current Opinion in Investigational Drugs , vol.4 , Issue.2 , pp. 172-178
    • Bronze, M.S.1    Greenfield, R.A.2
  • 6
    • 31144445870 scopus 로고    scopus 로고
    • Mechanisms of action of ribavirin against distinct viruses
    • DOI 10.1002/rmv.483
    • J.D. Graci, and C.E. Cameron Mechanisms of action of ribavirin against distinct viruses Rev Med Virol 16 2005 37 48 (Pubitemid 43133592)
    • (2006) Reviews in Medical Virology , vol.16 , Issue.1 , pp. 37-48
    • Graci, J.D.1    Cameron, C.E.2
  • 7
    • 84893704436 scopus 로고    scopus 로고
    • Involvement of the N-terminal portion of influenza virus RNA polymerase subunit PB1 in nucleotide recognition
    • N.T. Binh, C. Wakai, A. Kawaguchi, and K. Nagata Involvement of the N-terminal portion of influenza virus RNA polymerase subunit PB1 in nucleotide recognition Biochem Biophys Res Commun 443 2014 975 979
    • (2014) Biochem Biophys Res Commun , vol.443 , pp. 975-979
    • Binh, N.T.1    Wakai, C.2    Kawaguchi, A.3    Nagata, K.4
  • 8
    • 84891503721 scopus 로고    scopus 로고
    • Ribavirin inhibits in vitro hepatitis e virus replication through depletion of cellular GTP pools and is moderately synergistic with alpha interferon
    • Y. Debing, S.U. Emerson, Y. Wang, Q. Pan, J. Balzarini, K. Dallmeier, and J. Neyts Ribavirin inhibits in vitro hepatitis E virus replication through depletion of cellular GTP pools and is moderately synergistic with alpha interferon Antimicrob Agents Chemother 58 2014 267 273
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 267-273
    • Debing, Y.1    Emerson, S.U.2    Wang, Y.3    Pan, Q.4    Balzarini, J.5    Dallmeier, K.6    Neyts, J.7
  • 9
    • 79953025461 scopus 로고    scopus 로고
    • Mechanism of action of ribavirin in a novel hepatitis C virus replication cell system
    • K. Mori, M. Ikeda, Y. Ariumi, H. Dansako, T. Wakita, and N. Kato Mechanism of action of ribavirin in a novel hepatitis C virus replication cell system Virus Res 157 2011 61 70
    • (2011) Virus Res , vol.157 , pp. 61-70
    • Mori, K.1    Ikeda, M.2    Ariumi, Y.3    Dansako, H.4    Wakita, T.5    Kato, N.6
  • 11
    • 84880353282 scopus 로고    scopus 로고
    • Response of hepatitis C virus to long-term passage in the presence of alpha interferon: Multiple mutations and a common phenotype
    • C. Perales, N.M. Beach, I. Gallego, M.E. Soria, J. Quer, J.I. Esteban, C. Rice, E. Domingo, and J. Sheldon Response of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype J Virol 87 2013 7593 7607
    • (2013) J Virol , vol.87 , pp. 7593-7607
    • Perales, C.1    Beach, N.M.2    Gallego, I.3    Soria, M.E.4    Quer, J.5    Esteban, J.I.6    Rice, C.7    Domingo, E.8    Sheldon, J.9
  • 13
    • 33845992567 scopus 로고    scopus 로고
    • Activity of ribavirin against Hantaan virus correlates with production of ribavirin-5′-triphosphate, not with inhibition of IMP dehydrogenase
    • DOI 10.1128/AAC.00790-06
    • Y. Sun, D.-H. Chung, Y.-K. Chu, C.B. Jonsson, and W.B. Parker Activity of ribavirin against Hantaan virus correlates with production of ribavirin-5′-triphosphate, not with inhibition of IMP dehydrogenase Antimicrob Agents Chemother 51 2007 84 88 (Pubitemid 46047691)
    • (2007) Antimicrobial Agents and Chemotherapy , vol.51 , Issue.1 , pp. 84-88
    • Sun, Y.1    Chung, D.-H.2    Chu, Y.-K.3    Jonsson, C.B.4    Parker, W.B.5
  • 14
    • 35448991761 scopus 로고    scopus 로고
    • Ribavirin reveals a lethal threshold of allowable mutation frequency for Hantaan virus
    • DOI 10.1128/JVI.00874-07
    • D.-H. Chung, Y. Sun, W.B. Parker, J.B. Arterburn, A. Bartolucci, and C.B. Jonsson Ribavirin reveals a lethal threshold of allowable mutation frequency for Hantaan virus J Virol 81 2007 11722 11729 (Pubitemid 47623804)
    • (2007) Journal of Virology , vol.81 , Issue.21 , pp. 11722-11729
    • Chung, D.-H.1    Sun, Y.2    Parker, W.B.3    Arterburn, J.B.4    Bartolucci, A.5    Jonsson, C.B.6
  • 15
    • 77956209034 scopus 로고    scopus 로고
    • Cell type mediated resistance of vesicular stomatitis virus and Sendai virus to ribavirin
    • N.R. Shah, A. Sunderland, and V.Z. Grdzelishvili Cell type mediated resistance of vesicular stomatitis virus and Sendai virus to ribavirin PLoS ONE 5 2010 e11265
    • (2010) PLoS ONE , vol.5 , pp. 11265
    • Shah, N.R.1    Sunderland, A.2    Grdzelishvili, V.Z.3
  • 16
    • 84879840922 scopus 로고    scopus 로고
    • Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin
    • D. Falzarano, E. de Wit, C. Martellaro, J. Callison, V.J. Munster, and H. Feldmann Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin Sci Rep 3 2013 1686
    • (2013) Sci Rep , vol.3 , pp. 1686
    • Falzarano, D.1    De Wit, E.2    Martellaro, C.3    Callison, J.4    Munster, V.J.5    Feldmann, H.6
  • 17
    • 79960424334 scopus 로고    scopus 로고
    • Host-based ribavirin resistance influences hepatitis C virus replication and treatment response
    • K.D. Ibarra, M.K. Jain, and J.K. Pfeiffer Host-based ribavirin resistance influences hepatitis C virus replication and treatment response J Virol 85 2011 7273 7283
    • (2011) J Virol , vol.85 , pp. 7273-7283
    • Ibarra, K.D.1    Jain, M.K.2    Pfeiffer, J.K.3
  • 18
    • 73549116556 scopus 로고    scopus 로고
    • Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections
    • C. Perales, R. Agudo, H. Tejero, S.C. Manrubia, and E. Domingo Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections PLoS Pathog 5 2009 e1000658
    • (2009) PLoS Pathog , vol.5 , pp. 1000658
    • Perales, C.1    Agudo, R.2    Tejero, H.3    Manrubia, S.C.4    Domingo, E.5
  • 19
    • 84858602051 scopus 로고    scopus 로고
    • Mutagenesis-mediated virus extinction: Virus-dependent effect of viral load on sensitivity to lethal defection
    • H. Moreno, H. Tejero, J.C. la Torre de, E. Domingo, and V. Martín Mutagenesis-mediated virus extinction: virus-dependent effect of viral load on sensitivity to lethal defection PLoS ONE 7 2012 e32550
    • (2012) PLoS ONE , vol.7 , pp. 32550
    • Moreno, H.1    Tejero, H.2    La Torre De, J.C.3    Domingo, E.4    Martín, V.5
  • 21
    • 34248592912 scopus 로고    scopus 로고
    • Care of patients coinfected with HIV and hepatitis C virus: 2007 Updated recommendations from the HCV-HIV International Panel
    • DOI 10.1097/QAD.0b013e3281084e4d, PII 0000203020070531000001
    • V. Soriano, M. Puoti, M. Sulkowski, A. Cargnel, Y. Benhamou, M. Peters, S. Mauss, N. Bräu, A. Hatzakis, and S. Pol et al. Care of patients coinfected with HIV and hepatitis C virus: 2007 updated recommendations from the HCV-HIV International Panel AIDS 21 2007 1073 1089 (Pubitemid 46763278)
    • (2007) AIDS , vol.21 , Issue.9 , pp. 1073-1089
    • Soriano, V.1    Puoti, M.2    Sulkowski, M.3    Cargnel, A.4    Benhamou, Y.5    Peters, M.6    Mauss, S.7    Brau, N.8    Hatzakis, A.9    Pol, S.10    Rockstroh, J.11
  • 22
    • 77953768391 scopus 로고    scopus 로고
    • Successful treatment of disseminated human papillomavirus infection with pegylated interferon and ribavirin
    • N.K. Shrestha, and D.J. Hamrock Successful treatment of disseminated human papillomavirus infection with pegylated interferon and ribavirin Clin Infect Dis 51 2010 e4 e6
    • (2010) Clin Infect Dis , vol.51
    • Shrestha, N.K.1    Hamrock, D.J.2
  • 24
    • 84898667144 scopus 로고    scopus 로고
    • Treatment of human papillomavirus infection with interferon alpha and ribavirin in a patient with acquired aplastic anemia
    • 10.1016/j.ijid.2013.11.021
    • C. Mosa, A. Trizzino, A. Trizzino, F. Di Marco, P. D'Angelo, and P. Farruggia Treatment of human papillomavirus infection with interferon alpha and ribavirin in a patient with acquired aplastic anemia Int J Infect Dis 2014 10.1016/j.ijid.2013.11.021
    • (2014) Int J Infect Dis
    • Mosa, C.1    Trizzino, A.2    Trizzino, A.3    Di Marco, F.4    D'Angelo, P.5    Farruggia, P.6
  • 26
    • 66149098217 scopus 로고    scopus 로고
    • Effect of ribavirin on the mutation rate and spectrum of hepatitis C virus in vivo
    • J.M. Cuevas, F. González-Candelas, A. Moya, and R. Sanjuán Effect of ribavirin on the mutation rate and spectrum of hepatitis C virus in vivo J Virol 83 2009 5760 5764
    • (2009) J Virol , vol.83 , pp. 5760-5764
    • Cuevas, J.M.1    González-Candelas, F.2    Moya, A.3    Sanjuán, R.4
  • 28
    • 84897962845 scopus 로고    scopus 로고
    • Oral ribavirin therapy for respiratory syncytial virus infections in moderately to severely immunocompromised patients
    • Clinic Hematology/oncology And Transplant Infectious Diseases Services M.
    • J.R. Marcelin, J.W. Wilson, R.R. Razonable, and Mayo Clinic Hematology/Oncology and Transplant Infectious Diseases Services Oral ribavirin therapy for respiratory syncytial virus infections in moderately to severely immunocompromised patients Transpl Infect Dis 16 2014 242 250
    • (2014) Transpl Infect Dis , vol.16 , pp. 242-250
    • Marcelin, J.R.1    Wilson, J.W.2    Razonable, R.R.3
  • 29
    • 84901260022 scopus 로고    scopus 로고
    • Early use of ribavirin is beneficial in crimean-congo hemorrhagic fever
    • S.B. Ozbey, C. Kader, A. Erbay, and O. Ergönül Early use of ribavirin is beneficial in crimean-congo hemorrhagic fever Vector Borne Zoonotic Dis 14 2014 300 302
    • (2014) Vector Borne Zoonotic Dis , vol.14 , pp. 300-302
    • Ozbey, S.B.1    Kader, C.2    Erbay, A.3    Ergönül, O.4
  • 30
    • 84901258149 scopus 로고    scopus 로고
    • Treatment of persistent rhinovirus infection with pegylated interferon-α2a and ribavirin in patients with hypogammaglobulinemia
    • 10.1093/cid/ciu169
    • O. Ruuskanen, M. Waris, and L. Kainulainen Treatment of persistent rhinovirus infection with pegylated interferon-α2a and ribavirin in patients with hypogammaglobulinemia Clin Infect Dis 2014 10.1093/cid/ciu169
    • (2014) Clin Infect Dis
    • Ruuskanen, O.1    Waris, M.2    Kainulainen, L.3
  • 32
    • 84887344819 scopus 로고    scopus 로고
    • Ribavirin protects Syrian hamsters against lethal hantavirus pulmonary syndrome - After intranasal exposure to Andes virus
    • M. Ogg, C.B. Jonsson, J.V. Camp, and J.W. Hooper Ribavirin protects Syrian hamsters against lethal hantavirus pulmonary syndrome - after intranasal exposure to Andes virus Viruses 5 2013 2704 2720
    • (2013) Viruses , vol.5 , pp. 2704-2720
    • Ogg, M.1    Jonsson, C.B.2    Camp, J.V.3    Hooper, J.W.4
  • 33
    • 0038809107 scopus 로고    scopus 로고
    • A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity
    • DOI 10.1073/pnas.1232294100
    • J.K. Pfeiffer, and K. Kirkegaard A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity Proc Natl Acad Sci U S A 100 2003 7289 7294 (Pubitemid 36706431)
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.12 , pp. 7289-7294
    • Pfeiffer, J.K.1    Kirkegaard, K.2
  • 34
    • 38949184924 scopus 로고    scopus 로고
    • Engineering attenuated virus vaccines by controlling replication fidelity
    • DOI 10.1038/nm1726, PII NM1726
    • M. Vignuzzi, E. Wendt, and R. Andino Engineering attenuated virus vaccines by controlling replication fidelity Nat Med 14 2008 154 161 (Pubitemid 351214560)
    • (2008) Nature Medicine , vol.14 , Issue.2 , pp. 154-161
    • Vignuzzi, M.1    Wendt, E.2    Andino, R.3
  • 35
    • 84873023551 scopus 로고    scopus 로고
    • Ribavirin-resistant mutants of human enterovirus 71 express a high replication fidelity phenotype during growth in cell culture
    • S. Sadeghipour, E.J. Bek, and P.C. McMinn Ribavirin-resistant mutants of human enterovirus 71 express a high replication fidelity phenotype during growth in cell culture J Virol 87 2013 1759 1769
    • (2013) J Virol , vol.87 , pp. 1759-1769
    • Sadeghipour, S.1    Bek, E.J.2    McMinn, P.C.3
  • 36
    • 84881162575 scopus 로고    scopus 로고
    • An increased replication fidelity mutant of foot-and-mouth disease virus retains fitness in vitro and virulence in vivo
    • J. Zeng, H. Wang, X. Xie, D. Yang, G. Zhou, and L. Yu An increased replication fidelity mutant of foot-and-mouth disease virus retains fitness in vitro and virulence in vivo Antiviral Res 100 2013 1 7
    • (2013) Antiviral Res , vol.100 , pp. 1-7
    • Zeng, J.1    Wang, H.2    Xie, X.3    Yang, D.4    Zhou, G.5    Yu, L.6
  • 37
    • 78449244303 scopus 로고    scopus 로고
    • Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds
    • L.I. Levi, N.F. Gnädig, S. Beaucourt, M.J. McPherson, B. Baron, J.J. Arnold, and M. Vignuzzi Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds PLoS Pathog 6 2010 e1001163
    • (2010) PLoS Pathog , vol.6 , pp. 1001163
    • Levi, L.I.1    Gnädig, N.F.2    Beaucourt, S.3    McPherson, M.J.4    Baron, B.5    Arnold, J.J.6    Vignuzzi, M.7
  • 38
    • 84899079298 scopus 로고    scopus 로고
    • Attenuation of human enterovirus 71 high-replication-fidelity variants in AG129 mice
    • T. Meng, and J. Kwang Attenuation of human enterovirus 71 high-replication-fidelity variants in AG129 mice J Virol 88 2014 5803 5815
    • (2014) J Virol , vol.88 , pp. 5803-5815
    • Meng, T.1    Kwang, J.2
  • 40
    • 13444310882 scopus 로고    scopus 로고
    • Ribavirin resistance in hepatitis C virus replicon-containing cell lines conferred by changes in the cell line or mutations in the replicon RNA
    • DOI 10.1128/JVI.79.4.2346-2355.2005
    • J.K. Pfeiffer, and K. Kirkegaard Ribavirin resistance in hepatitis C virus replicon-containing cell lines conferred by changes in the cell line or mutations in the replicon RNA J Virol 79 2005 2346 2355 (Pubitemid 40204589)
    • (2005) Journal of Virology , vol.79 , Issue.4 , pp. 2346-2355
    • Pfeiffer, J.K.1    Kirkegaard, K.2
  • 41
    • 80051590863 scopus 로고    scopus 로고
    • Selection of hepatitis C virus resistant to ribavirin
    • D.A. Feigelstock, K.B. Mihalik, and S.M. Feinstone Selection of hepatitis C virus resistant to ribavirin Virol J 8 2011 402
    • (2011) Virol J , vol.8 , pp. 402
    • Feigelstock, D.A.1    Mihalik, K.B.2    Feinstone, S.M.3
  • 42
    • 84883501016 scopus 로고    scopus 로고
    • Sensitivity of a ribavirin resistant mutant of hepatitis C virus to other antiviral drugs
    • K.B. Mihalik, and D.A. Feigelstock Sensitivity of a ribavirin resistant mutant of hepatitis C virus to other antiviral drugs PLoS ONE 8 2013 e74027
    • (2013) PLoS ONE , vol.8 , pp. 74027
    • Mihalik, K.B.1    Feigelstock, D.A.2
  • 43
    • 84896904367 scopus 로고    scopus 로고
    • Ribavirin-resistant variants of foot-and-mouth disease virus: The effect of restricted quasispecies diversity on viral virulence
    • 10.1128/JVI.03594-13
    • J. Zeng, H. Wang, X. Xie, C. Li, G. Zhou, D. Yang, and L. Yu Ribavirin-resistant variants of foot-and-mouth disease virus: the effect of restricted quasispecies diversity on viral virulence J Virol 2014 10.1128/JVI.03594-13
    • (2014) J Virol
    • Zeng, J.1    Wang, H.2    Xie, X.3    Li, C.4    Zhou, G.5    Yang, D.6    Yu, L.7
  • 44
    • 57349131683 scopus 로고    scopus 로고
    • Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin
    • A. Arias, J.J. Arnold, M. Sierra, E.D. Smidansky, E. Domingo, and C.E. Cameron Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin J Virol 82 2008 12346 12355
    • (2008) J Virol , vol.82 , pp. 12346-12355
    • Arias, A.1    Arnold, J.J.2    Sierra, M.3    Smidansky, E.D.4    Domingo, E.5    Cameron, C.E.6
  • 49
    • 84883438898 scopus 로고    scopus 로고
    • Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: Evidence for proofreading and potential therapeutics
    • E.C. Smith, H. Blanc, M. Vignuzzi, and M.R. Denison Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics PLoS Pathog 9 2013 e1003565
    • (2013) PLoS Pathog , vol.9 , pp. 1003565
    • Smith, E.C.1    Blanc, H.2    Vignuzzi, M.3    Denison, M.R.4
  • 50
    • 11844292013 scopus 로고    scopus 로고
    • Ribavirin and lethal mutagenesis of poliovirus: Molecular mechanisms, resistance and biological implications
    • DOI 10.1016/j.virusres.2004.11.007, PII S0168170204004010, Virus Entry into Error Catastrophe as a New Antiviral Strategy
    • M. Vignuzzi, J.K. Stone, and R. Andino Ribavirin and lethal mutagenesis of poliovirus: molecular mechanisms, resistance and biological implications Virus Res 107 2005 173 181 (Pubitemid 40093090)
    • (2005) Virus Research , vol.107 , Issue.2 , pp. 173-181
    • Vignuzzi, M.1    Stone, J.K.2    Andino, R.3
  • 51
    • 36048969246 scopus 로고    scopus 로고
    • High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants
    • DOI 10.1128/JVI.01296-07
    • L.D. Eckerle, X. Lu, S.M. Sperry, L. Choi, and M.R. Denison High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants J Virol 81 2007 12135 12144 (Pubitemid 350085829)
    • (2007) Journal of Virology , vol.81 , Issue.22 , pp. 12135-12144
    • Eckerle, L.D.1    Lu, X.2    Sperry, S.M.3    Choi, L.4    Denison, M.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.