Involvement of the N-terminal portion of influenza virus RNA polymerase subunit PB1 in nucleotide recognition

Biochemical and Biophysical Research Communications

Volumn 443, Issue 3, 2014, Pages 975-979

  Binh, Nguyen Trong ^a   Wakai, Chitose ^a   Kawaguchi, Atsushi ^a   Nagata, Kyosuke ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Influenza; Nucleotide recognition; Resistant mutant; Ribavirin

Indexed keywords

METHOTREXATE; NUCLEOTIDE; RIBAVIRIN; RNA DIRECTED RNA POLYMERASE; RNA POLYMERASE SUBUNIT PB1; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; CONTROLLED STUDY; DNA LIBRARY; ENZYME ACTIVE SITE; IC 50; INFLUENZA VIRUS; MDCK CELL; MOLECULAR RECOGNITION; MUTAGENESIS; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA SYNTHESIS; VIRUS MUTANT;

ORTHOMYXOVIRIDAE; RNA VIRUSES;

INFLUENZA; NUCLEOTIDE RECOGNITION; RESISTANT MUTANT; RIBAVIRIN;

ANIMALS; BASE SEQUENCE; DNA MUTATIONAL ANALYSIS; DOGS; DRUG RESISTANCE, VIRAL; HEK293 CELLS; HUMANS; MADIN DARBY CANINE KIDNEY CELLS; METHOTREXATE; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION; NUCLEOTIDES; PROTEIN SUBUNITS; REPLICON; RIBAVIRIN; RNA REPLICASE; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL PROTEINS;

EID: 84893704436     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.12.071     Document Type: Article

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