Treatment of persistent rhinovirus infection with pegylated interferon α2a and ribavirin in patients with hypogammaglobulinemia

Clinical Infectious Diseases

Volumn 58, Issue 12, 2014, Pages 1784-1786

  Ruuskanen, Olli ^a   Waris, Matti ^b   Kainulainen, Leena ^a  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

PEGINTERFERON ALPHA2A; RIBAVIRIN; ALPHA INTERFERON; ANTIVIRUS AGENT; MACROGOL DERIVATIVE; RECOMBINANT PROTEIN;

ADULT; ANTIVIRAL ACTIVITY; CASE REPORT; CHILD; DRUG EFFICACY; DRUG FEVER; GENE EXPRESSION; GRAFT RECIPIENT; HUMAN; IMMUNOGLOBULIN DEFICIENCY; INFORMED CONSENT; INTERFERON INDUCTION; LETTER; MALE; NOSE SMEAR; PERSISTENT INFECTION; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; QUALITY OF LIFE; RHINOVIRUS; RHINOVIRUS INFECTION; SPUTUM CULTURE; VIRAL CLEARANCE; VIRUS REPLICATION; YOUNG ADULT; AGAMMAGLOBULINEMIA; CHRONIC DISEASE; COMMON VARIABLE IMMUNODEFICIENCY; COMPLICATION; DRUG COMBINATION; MIDDLE AGED; PICORNAVIRIDAE INFECTIONS; VIROLOGY;

AGAMMAGLOBULINEMIA; ANTIVIRAL AGENTS; CHRONIC DISEASE; COMMON VARIABLE IMMUNODEFICIENCY; DRUG THERAPY, COMBINATION; HUMANS; INTERFERON-ALPHA; MALE; MIDDLE AGED; PICORNAVIRIDAE INFECTIONS; POLYETHYLENE GLYCOLS; RECOMBINANT PROTEINS; RHINOVIRUS; RIBAVIRIN;

EID: 84901258149     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/ciu169     Document Type: Letter

References (10)

1. Ruuskanen O, Waris M, Ramilo O. New aspects on human rhinovirus infections. Pediatr Infect Dis J 2013; 32:553-5.
2. Singanayagam A, Joshi PV, Mallia P, Johnston SL. Viruses exacerbating chronic pulmonary disease: the role of immune modulation. BMC Med 2012; 10:27.
3. Peltola V, Waris M, Kainulainen L, Kero J, Ruuskanen O. Virus shedding after human rhinovirus infection in children, adults and patients with hypogammaglobulinemia. Clin Microbiol Infect 2013; 19: e322-7.
4. Kainulainen L, Vuorinen T, Rantakokko-Jalava K, Österback R, Ruuskanen O. Recurrent and persistent respiratory tract viral infections in patients with primary hypogammaglobulinemia. J Allergy Clin Immunol 2010; 126:120-6.
5. Kaiser L, Aubert JD, Pache JC, et al. Chronic rhinoviral infection in lung transplant recipients. Am J Respir Crit Care Med 2006; 15:1392-9.
6. Flight WG, Bright-Thomas RJ, Tilston P, et al. Chronic rhinovirus infection in an adult with cystic fibrosis. J Clin Microbiol 2013; 51:3893-6.
7. Becker TM, Durrani SR, Bochkov YA, Devries MK, Rajamanickam V, Jackson DJ. Effect of exogenous interferons on rhinovirus replication and airway inflammatory responses. Ann Allergy Asthma Immunol 2013; 111:397-401.
8. Bellingan G, Maksimov M, Howell DC, et al. The effect of intravenous interferon-beta-1a (FP-1201) on lung CD73 expression and on acute respiratory distress syndrome mortality: an open-label study. Lancet Respir Dis 2014; 2:98-107.
9. Ivashkiv LB, Donlin LT. Regulation of type I interferon responses. Nat Immunol 2014; 14:36-49.
10. Falzarano D, de Wit E, Rasmussen AL, et al. Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoVinfected rhesus macaques. Nat Med 2013; 19:1313-7.