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Volumn 9, Issue 6, 2014, Pages 595-607

Advances in asthma drug discovery: Evaluating the potential of nasal cell sampling and beyond

Author keywords

Allergic rhinitis; Artificial airways; Asthma; Inflammation; Nasal cells

Indexed keywords

ANTIINFLAMMATORY AGENT; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BIOLOGICAL MARKER; CHOLINERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID; EOTAXIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HISTAMINE H1 RECEPTOR ANTAGONIST; IMMUNOGLOBULIN E ANTIBODY; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; LEUKOTRIENE; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 3; PHOSPHORYL LIPID A; RANTES; RECOMBINANT ALLERGEN; VACCINE; ANTIASTHMATIC AGENT;

EID: 84901250675     PISSN: 17460441     EISSN: 1746045X     Source Type: Journal    
DOI: 10.1517/17460441.2014.909403     Document Type: Review
Times cited : (9)

References (131)
  • 1
    • 80053330950 scopus 로고    scopus 로고
    • Novel cytokine-directed therapies for asthma
    • Walsh GM. Novel cytokine-directed therapies for asthma. Discov Med 2011;11(59):283-91
    • (2011) Discov Med , vol.11 , Issue.59 , pp. 283-291
    • Walsh, G.M.1
  • 2
    • 77954033984 scopus 로고    scopus 로고
    • New therapies for asthma: Is there any progress
    • Barnes PJ. New therapies for asthma: Is there any progress? Trends Pharmacol Sci 2010;31(7):335-43
    • (2010) Trends Pharmacol Sci , vol.31 , Issue.7 , pp. 335-343
    • Barnes, P.J.1
  • 3
    • 80051548564 scopus 로고    scopus 로고
    • The increasing challenge of discovering asthma drugs
    • Mullane K. The increasing challenge of discovering asthma drugs. Biochem Pharmacol 2011;82(6):586-99
    • (2011) Biochem Pharmacol , vol.82 , Issue.6 , pp. 586-599
    • Mullane, K.1
  • 4
    • 33845540077 scopus 로고    scopus 로고
    • Animal models of asthma-Pro: Allergic avoidance of animal (model[s]) is not an option
    • DOI 10.1164/rccm.2609001
    • Shapiro SD. Animal models of asthma: Pro: Allergic avoidance of animal (model [s]) is not an option. Am J Respir Crit Care Med 2006;174(11):1171-3 (Pubitemid 44924814
    • (2006) American Journal of Respiratory and Critical Care Medicine , vol.174 , Issue.11 , pp. 1171-1173
    • Shapiro, S.D.1
  • 5
    • 50849124795 scopus 로고    scopus 로고
    • The use of transgenic mice for modeling airways disease
    • Shapiro SD. The use of transgenic mice for modeling airways disease Pulm Pharmacol Ther 2008;21(5):699-701
    • (2008) Pulm Pharmacol Ther , vol.21 , Issue.5 , pp. 699-701
    • Shapiro, S.D.1
  • 6
    • 81255154034 scopus 로고    scopus 로고
    • Artificial airways for the study of respiratory disease
    • Swindle EJ, Davies DE. Artificial airways for the study of respiratory disease. Expert Rev Respir Med 2011;5(6):757-65
    • (2011) Expert Rev Respir Med , vol.5 , Issue.6 , pp. 757-765
    • Swindle, E.J.1    Davies, D.E.2
  • 7
    • 33845543076 scopus 로고    scopus 로고
    • The mouse trap: It still yields few answers in asthma
    • 1173-6 discussion
    • Wenzel S, Holgate ST. The mouse trap: It still yields few answers in asthma. Am J Respir Crit Care Med 2006;174(11):1173-6; discussion 76-8
    • (2006) Am J Respir Crit Care Med , vol.174 , Issue.11 , pp. 76-78
    • Wenzel, S.1    Holgate, S.T.2
  • 8
    • 0026033668 scopus 로고
    • The safety aspects of fiberoptic bronchoscopy, bronchoalveolar lavage, and endobronchial biopsy in asthma
    • Djukanovic R, Wilson JW, Lai CK, et al. The safety aspects of fiberoptic bronchoscopy, bronchoalveolar lavage, and endobronchial biopsy in asthma. Am Rev Respir Dis 1991;143(4 Pt 1):772-7
    • (1991) Am Rev Respir Dis , vol.143 , Issue.4 PART 1 , pp. 772-777
    • Djukanovic, R.1    Wilson, J.W.2    Lai, C.K.3
  • 12
    • 40549093007 scopus 로고    scopus 로고
    • Allergic rhinitis and its impact on asthma (aria 2008 update (in collaboration with the world health organization, ga(2)len and allergen
    • Bousquet J, Khaltaev N, Cruz AA, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 2008;63(Suppl 86):8-160
    • (2008) Allergy , vol.63 , Issue.SUPPL. 86 , pp. 8-160
    • Bousquet, J.1    Khaltaev, N.2    Cruz, A.A.3
  • 13
    • 53749097483 scopus 로고    scopus 로고
    • Nasal epithelial cells as surrogates for bronchial epithelial cells in airway inflammation studies
    • McDougall CM, Blaylock MG, Douglas JG, et al. Nasal epithelial cells as surrogates for bronchial epithelial cells in airway inflammation studies. Am J Respir Cell Mol Biol 2008;39(5):560-8
    • (2008) Am J Respir Cell Mol Biol , vol.39 , Issue.5 , pp. 560-568
    • McDougall, C.M.1    Blaylock, M.G.2    Douglas, J.G.3
  • 14
    • 83555176222 scopus 로고    scopus 로고
    • Asthma in adults and its association with chronic rhinosinusitis: The ga2len survey in europe
    • Jarvis D, Newson R, Lotvall J, et al. Asthma in adults and its association with chronic rhinosinusitis: The GA2LEN survey in Europe. Allergy 2012;67(1):91-8
    • (2012) Allergy , vol.67 , Issue.1 , pp. 91-98
    • Jarvis, D.1    Newson, R.2    Lotvall, J.3
  • 16
    • 0031047374 scopus 로고    scopus 로고
    • One airway, one disease
    • SUPPL
    • Grossman J. One airway, one disease. Chest 1997;111(2 Suppl):11S-6S (Pubitemid 27100613
    • (1997) Chest , vol.111 , Issue.2
    • Grossman, J.1
  • 17
    • 0033226964 scopus 로고    scopus 로고
    • American Thoracic Society Workshop. Immunobiology of asthma and rhinitis. Pathogenic factors and therapeutic options
    • American Thoracic Society Workshop. Immunobiology of asthma and rhinitis. Pathogenic factors and therapeutic options. Am J Respir Crit Care Med 1999;160(5 Pt 1):1778-87
    • (1999) Am J Respir Crit Care Med , vol.160 , Issue.5 PART 1 , pp. 1778-1787
  • 18
    • 0032822390 scopus 로고    scopus 로고
    • Allergic rhinobronchitis: The asthma-Allergic rhinitis link
    • Simons FE. Allergic rhinobronchitis: The asthma-Allergic rhinitis link. J Allergy Clin Immunol 1999;104(3 Pt 1):534-40
    • (1999) J Allergy Clin Immunol , vol.104 , Issue.3 PART 1 , pp. 534-540
    • Simons, F.E.1
  • 19
    • 0026847350 scopus 로고
    • Immunohistology of the nasal mucosa in seasonal allergic rhinitis: Increases in activated eosinophils and epithelial mast cells
    • Bentley AM, Jacobson MR, Cumberworth V, et al. Immunohistology of the nasal mucosa in seasonal allergic rhinitis: Increases in activated eosinophils and epithelial mast cells. J Allergy Clin Immunol 1992;89(4):877-83
    • (1992) J Allergy Clin Immunol , vol.89 , Issue.4 , pp. 877-883
    • Bentley, A.M.1    Jacobson, M.R.2    Cumberworth, V.3
  • 20
    • 0031808268 scopus 로고    scopus 로고
    • Influence of treatment on the nose and/or the lungs
    • Pauwels R. Influence of treatment on the nose and/or the lungs. Clin Exp Allergy 1998;28(Suppl 2):37-40
    • (1998) Clin Exp Allergy , vol.28 , Issue.SUPPL. 2 , pp. 37-40
    • Pauwels, R.1
  • 22
    • 1242270608 scopus 로고    scopus 로고
    • Leukotriene receptor antagonists for allergic rhinitis: A systematic review and meta-Analysis
    • DOI 10.1016/j.amjmed.2003.10.030
    • Wilson AM, O'Byrne PM, Parameswaran K. Leukotriene receptor antagonists for allergic rhinitis: A systematic review and meta-Analysis. Am J Med 2004;116(5):338-44 (Pubitemid 38230294
    • (2004) American Journal of Medicine , vol.116 , Issue.5 , pp. 338-344
    • Wilson, A.M.1    O'Byrne, P.M.2    Parameswaran, K.3
  • 27
    • 85122080487 scopus 로고    scopus 로고
    • Intranasal corticosteroids for asthma control in people with coexisting asthma and rhinitis
    • Taramarcaz P, Gibson PG. Intranasal corticosteroids for asthma control in people with coexisting asthma and rhinitis. Cochrane Database Syst Rev 2003(4):CD003570
    • (2003) Cochrane Database Syst Rev , vol.4
    • Taramarcaz, P.1    Gibson, P.G.2
  • 29
    • 0031787542 scopus 로고    scopus 로고
    • Executive summary of joint task force practice parameters on diagnosis and management of rhinitis
    • Dykewicz MS, Fineman S. Executive Summary of Joint Task Force Practice Parameters on Diagnosis and Management of Rhinitis. Ann Allergy Asthma Immunol 1998;81(5 Pt 2):463-8 (Pubitemid 28553775
    • (1998) Annals of Allergy, Asthma and Immunology , vol.81 , Issue.5 PART 2 , pp. 463-468
    • Dykewicz, M.S.1
  • 30
    • 34047161743 scopus 로고    scopus 로고
    • Allergic rhinitis and its impact on asthma update: Allergen immunotherapy
    • Global Allergy Asthma European Network
    • Passalacqua G, Durham SR; Global Allergy and Asthma European Network. Allergic rhinitis and its impact on asthma update: Allergen immunotherapy. J Allergy Clin Immunol 2007;119(4):881-91
    • (2007) J Allergy Clin Immunol , vol.119 , Issue.4 , pp. 881-891
    • Passalacqua, G.1    Durham, S.R.2
  • 33
    • 22844441207 scopus 로고    scopus 로고
    • ARIA: Impact of compliance
    • Van Cauwenberge P. ARIA: Impact of compliance. Clin Exp Allergy Rev 2005;5(1):1472-9733
    • (2005) Clin Exp Allergy Rev , vol.5 , Issue.1 , pp. 1472-9733
    • Van Cauwenberge, P.1
  • 34
    • 77956378655 scopus 로고    scopus 로고
    • Allergic rhinitis and its impact on asthma (aria) guidelines: 2010 revision
    • Brozek JL, Bousquet J, Baena-Cagnani CE, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision. J Allergy Clin Immunol 2010;126(3):466-76
    • (2010) J Allergy Clin Immunol , vol.126 , Issue.3 , pp. 466-476
    • Brozek, J.L.1    Bousquet, J.2    Baena-Cagnani, C.E.3
  • 36
    • 84864803820 scopus 로고    scopus 로고
    • Nasal and bronchial inflammation after nasal allergen challenge: Assessment using noninvasive methods
    • Serrano CD, Valero A, Bartra J, et al. Nasal and bronchial inflammation after nasal allergen challenge: Assessment using noninvasive methods. J Investig Allergol Clin Immunol 2012;22(5):351-6
    • (2012) J Investig Allergol Clin Immunol , vol.22 , Issue.5 , pp. 351-356
    • Serrano, C.D.1    Valero, A.2    Bartra, J.3
  • 38
    • 0026730709 scopus 로고
    • Immunohistology of the nasal mucosa following allergeninduced rhinitis identification of activated t lymphocytes, eosinophils, and neutrophils
    • Varney VA, Jacobson MR, Sudderick RM, et al. Immunohistology of the nasal mucosa following allergeninduced rhinitis. Identification of activated T lymphocytes, eosinophils, and neutrophils. Am Rev Respir Dis 1992;146(1):170-6
    • (1992) Am Rev Respir Dis , vol.146 , Issue.1 , pp. 170-176
    • Varney, V.A.1    Jacobson, M.R.2    Sudderick, R.M.3
  • 39
    • 14644401137 scopus 로고    scopus 로고
    • Objective monitoring of nasal airway inflammation in rhinitis
    • Howarth PH, Persson CG, Meltzer EO, et al. Objective monitoring of nasal airway inflammation in rhinitis. J Allergy Clin Immunol 2005;115(3 Suppl 1):S414-41
    • (2005) J Allergy Clin Immunol , vol.115 , Issue.3 SUPPL. 1
    • Howarth, P.H.1    Persson, C.G.2    Meltzer, E.O.3
  • 40
    • 33750365602 scopus 로고    scopus 로고
    • Immunoregulation by targeting T cells in the treatment of allergy and asthma
    • DOI 10.1016/j.coi.2006.09.013, PII S0952791506001981
    • Larche M. Immunoregulation by targeting T cells in the treatment of allergy and asthma. Curr Opin Immunol 2006;18(6):745-50 (Pubitemid 44635181
    • (2006) Current Opinion in Immunology , vol.18 , Issue.6 , pp. 745-750
    • Larche, M.1
  • 41
    • 70349852928 scopus 로고    scopus 로고
    • The efficacy of sublingual immunotherapy for house dust mites respiratory allergy: Results of a ga2len meta-Analysis
    • Compalati E, Passalacqua G, Bonini M, Canonica GW. The efficacy of sublingual immunotherapy for house dust mites respiratory allergy: Results of a GA2LEN meta-Analysis. Allergy 2009;64(11):1570-9
    • (2009) Allergy , vol.64 , Issue.11 , pp. 1570-1579
    • Compalati, E.1    Passalacqua, G.2    Bonini, M.3    Canonica, G.W.4
  • 42
    • 0030859918 scopus 로고    scopus 로고
    • Double-blind placebo-controlled study of sublingual immunotherapy with house dust mite extract (D.Pt.) in children
    • Hirsch T, Sahn M, Leupold W. Double-blind placebo-controlled study of sublingual immunotherapy with house dust mite extract (D.pt.) in children. Pediatr Allergy Immunol 1997;8(1):21-7 (Pubitemid 27365651
    • (1997) Pediatric Allergy and Immunology , vol.8 , Issue.1 , pp. 21-27
    • Hirsch, T.H.1    Sahn, M.2    Leupold, W.3
  • 44
    • 0026581306 scopus 로고
    • Topical vasoconstrictor (oxymetazoline) does not affect histamine-induced mucosal exudation of plasma in human nasal airways
    • Svensson C, Pipkorn U, Alkner U, et al. Topical vasoconstrictor (oxymetazoline) does not affect histamine-induced mucosal exudation of plasma in human nasal airways. Clin Exp Allergy 1992;22(3):411-16
    • (1992) Clin Exp Allergy , vol.22 , Issue.3 , pp. 411-416
    • Svensson, C.1    Pipkorn, U.2    Alkner, U.3
  • 45
    • 0031905895 scopus 로고    scopus 로고
    • Inflammatory mediators in naturally occurring rhinitis
    • DOI 10.1046/j.1365-2222.1998.00235.x
    • Wilson SJ, Lau L, Howarth PH. Inflammatory mediators in naturally occurring rhinitis. Clin Exp Allergy 1998;28(2):220-7 (Pubitemid 28137338
    • (1998) Clinical and Experimental Allergy , vol.28 , Issue.2 , pp. 220-227
    • Wilson, S.J.1    Lau, L.2    Howarth, P.H.3
  • 46
    • 0027333560 scopus 로고
    • Interleukin-6 and interleukin-1 alpha production is associated with antigen-induced late nasal response
    • Gosset P, Malaquin F, Delneste Y, et al. Interleukin-6 and interleukin-1 alpha production is associated with antigen-induced late nasal response. J Allergy Clin Immunol 1993;92(6):878-90
    • (1993) J Allergy Clin Immunol , vol.92 , Issue.6 , pp. 878-890
    • Gosset, P.1    Malaquin, F.2    Delneste, Y.3
  • 49
    • 0027087201 scopus 로고
    • Indirect evidence of nasal inflammation assessed by titration of inflammatory mediators and enumeration of cells in nasal secretions of patients with chronic rhinitis
    • DOI 10.1016/0091-6749(92)90460-J
    • Knani J, Campbell A, Enander I, et al. Indirect evidence of nasal inflammation assessed by titration of inflammatory mediators and enumeration of cells in nasal secretions of patients with chronic rhinitis. J Allergy Clin Immunol 1992;90(6 Pt 1):880-9 (Pubitemid 23004584
    • (1992) Journal of Allergy and Clinical Immunology , vol.90 , Issue.6 PART 1 , pp. 880-889
    • Knani, J.1    Campbell, A.2    Enander, I.3    Peterson, C.G.B.4    Michel, F.-B.5    Bousquet, J.6
  • 51
    • 0034020824 scopus 로고    scopus 로고
    • Low levels of interferon-γ in nasal fluid accompany raised levels of T-helper 2 cytokines in children with ongoing allergic rhinitis
    • DOI 10.1034/j.1399-3038.2000.00051.x
    • Benson M, Strannegard IL, Wennergren G, Strannegard O. Low levels of interferon-gamma in nasal fluid accompany raised levels of T-helper 2 cytokines in children with ongoing allergic rhinitis. Pediatr Allergy Immunol 2000;11(1):20-8 (Pubitemid 30168881
    • (2000) Pediatric Allergy and Immunology , vol.11 , Issue.1 , pp. 20-28
    • Benson, M.1    Strannegard, I.-L.2    Wennergren, G.3    Strannegard, O.4
  • 52
    • 0029731174 scopus 로고    scopus 로고
    • Intranasal fluticasone propionate inhibits recovery of chemokines and other cytokines in nasal secretions in allergen-induced rhinitis
    • Weido AJ, Reece LM, Alam R, et al. Intranasal fluticasone propionate inhibits recovery of chemokines and other cytokines in nasal secretions in allergen-induced rhinitis. Ann Allergy Asthma Immunol 1996;77(5):407-15 (Pubitemid 26422079
    • (1996) Annals of Allergy, Asthma and Immunology , vol.77 , Issue.5 , pp. 407-415
    • Weido, A.J.1    Reece, L.M.2    Alam, R.3    Cook, C.K.4    Sim, T.C.5
  • 54
    • 27744574230 scopus 로고    scopus 로고
    • Nasal lavage fluid concentrations of eotaxin-1 (CCL11) in naturally occurring allergic rhinitis: Relationship to disease activity, nasal luminal eosinophil influx, and plasma protein exudation
    • DOI 10.1111/j.1365-2222.2005.02236.x
    • Salib RJ, Lau LC, Howarth PH. Nasal lavage fluid concentrations of eotaxin-1 (CCL11) in naturally occurring allergic rhinitis: Relationship to disease activity, nasal luminal eosinophil influx, and plasma protein exudation. Clin Exp Allergy 2005;35(8):995-1002 (Pubitemid 41603132
    • (2005) Clinical and Experimental Allergy , vol.35 , Issue.8 , pp. 995-1002
    • Salib, R.J.1    Lau, L.C.2    Howarth, P.H.3
  • 55
    • 0023220433 scopus 로고
    • Inhibition of mediator release in allergic rhinitis by pretreatment with topical glucocorticosteroids
    • Pipkorn U, Proud D, Lichtenstein LM, et al. Inhibition of mediator release in allergic rhinitis by pretreatment with topical glucocorticosteroids. N Engl J Med 1987;316(24):1506-10 (Pubitemid 17076234
    • (1987) New England Journal of Medicine , vol.316 , Issue.24 , pp. 1506-1510
    • Pipkorn, U.1    Proud, D.2    Lichtenstein, L.M.3
  • 56
    • 0026758456 scopus 로고
    • Development of a new technique for recovery of cytokines from inflammatory sites in situ
    • Alam R, Sim TC, Hilsmeier K, Grant JA. Development of a new technique for recovery of cytokines from inflammatory sites in situ. J Immunol Methods 1992;155(1):25-9
    • (1992) J Immunol Methods , vol.155 , Issue.1 , pp. 25-29
    • Alam, R.1    Sim, T.C.2    Hilsmeier, K.3    Grant, J.A.4
  • 58
    • 0033709747 scopus 로고    scopus 로고
    • Immediate effect of topical budesonide on allergen challenge-induced nasal mucosal fluid levels of granulocytemacrophage colony-stimulating factor and interleukin-5
    • Linden M, Svensson C, Andersson E, et al. Immediate effect of topical budesonide on allergen challenge-induced nasal mucosal fluid levels of granulocytemacrophage colony-stimulating factor and interleukin-5. Am J Respir Crit Care Med 2000;162(5):1705-8
    • (2000) Am J Respir Crit Care Med , vol.162 , Issue.5 , pp. 1705-1708
    • Linden, M.1    Svensson, C.2    Andersson, E.3
  • 60
    • 0023716187 scopus 로고
    • Methods for obtaining specimens from the nasal mucosa for morphological and biochemical analysis
    • Pipkorn U, Karlsson G. Methods for obtaining specimens from the nasal mucosa for morphological and biochemical analysis. Eur Respir J 1988;1(9):856-62
    • (1988) Eur Respir J , vol.1 , Issue.9 , pp. 856-862
    • Pipkorn, U.1    Karlsson, G.2
  • 61
    • 0023676315 scopus 로고
    • A brush method to harvest cells from the nasal mucosa for microscopic and biochemical analysis
    • Pipkorn U, Karlsson G, Enerback L. A brush method to harvest cells from the nasal mucosa for microscopic and biochemical analysis. J Immunol Methods 1988;112(1):37-42
    • (1988) J Immunol Methods , vol.112 , Issue.1 , pp. 37-42
    • Pipkorn, U.1    Karlsson, G.2    Enerback, L.3
  • 62
    • 0032835316 scopus 로고    scopus 로고
    • Effect of topical corticosteroids on seasonal increases in epithelial eosinophils and mast cells in allergic rhinitis: A comparison of nasal brush and biopsy methods
    • DOI 10.1046/j.1365-2222.1999.00608.x
    • Jacobson MR, Juliusson S, Lowhagen O, et al. Effect of topical corticosteroids on seasonal increases in epithelial eosinophils and mast cells in allergic rhinitis: A comparison of nasal brush and biopsy methods. Clin Exp Allergy 1999;29(10):1347-55 (Pubitemid 29467958
    • (1999) Clinical and Experimental Allergy , vol.29 , Issue.10 , pp. 1347-1355
    • Jacobson, M.R.1    Juliusson, S.2    Lowhagen, O.3    Balder, B.4    Kay, A.B.5    Durham, S.R.6
  • 65
    • 0024236048 scopus 로고
    • A biopsy method to obtain high quality specimens of nasal mucosa
    • Fokkens WJ, Vroom TM, Gerritsma V, Rijntjes E. A biopsy method to obtain high quality specimens of nasal mucosa. Rhinology 1988;26(4):293-5 (Pubitemid 19022669
    • (1988) Rhinology , vol.26 , Issue.4 , pp. 293-295
    • Fokkens, W.J.1    Vroom, T.M.2    Gerritsma, V.3    Rijntjes, E.4
  • 66
    • 0141840847 scopus 로고    scopus 로고
    • Methods for the assessment of endobronchial biopsies in clinical research: Application to studies of pathogenesis and the effects of treatment
    • Endobronchial Biopsy Workshop
    • Jeffery P, Holgate S, Wenzel S; Endobronchial Biopsy Workshop. Methods for the assessment of endobronchial biopsies in clinical research: Application to studies of pathogenesis and the effects of treatment. Am J Respir Crit Care Med 2003;168(6 Pt 2):S1-17
    • (2003) Am J Respir Crit Care Med , vol.168 , Issue.6 PART 2
    • Jeffery, P.1    Holgate, S.2    Wenzel, S.3
  • 68
    • 84893225787 scopus 로고    scopus 로고
    • Exhaled breath condensate, nasal eosinophil cationic protein level and nasal cytology during immunotherapy for cypress allergy
    • Ventura MT, Murgia N, Montuschi P, et al. Exhaled breath condensate, nasal eosinophil cationic protein level and nasal cytology during immunotherapy for cypress allergy. J Biol Regul Homeost Agents 2013;27(4):1083-9
    • (2013) J Biol Regul Homeost Agents , vol.27 , Issue.4 , pp. 1083-1089
    • Ventura, M.T.1    Murgia, N.2    Montuschi, P.3
  • 70
    • 0020540865 scopus 로고
    • Nasal disease: Mechanisms and classification
    • Connell JT. Nasal disease: Mechanisms and classification. Ann Allergy 1983;50(4):227-35 (Pubitemid 13124997
    • (1983) Annals of Allergy , vol.50 , Issue.4 , pp. 227-235
    • Connell, J.T.1
  • 71
    • 0031693606 scopus 로고    scopus 로고
    • Clinical and antiinflammatory effects of intranasal budesonide aqueous pump spray in the treatment of perennial allergic rhinitis
    • Meltzer EO. Clinical and antiinflammatory effects of intranasal budesonide aqueous pump spray in the treatment of perennial allergic rhinitis. Ann Allergy Asthma Immunol 1998;81(2):128-34 (Pubitemid 28413027
    • (1998) Annals of Allergy, Asthma and Immunology , vol.81 , Issue.2 , pp. 128-134
    • Meltzer, E.O.1
  • 72
    • 0027942660 scopus 로고
    • Nasal cytology in patients with allergic rhinitis: Effects of intranasal fluticasone propionate
    • DOI 10.1016/0091-6749(94)90178-3
    • Meltzer EO, Orgel HA, Rogenes PR, Field EA. Nasal cytology in patients with allergic rhinitis: Effects of intranasal fluticasone propionate. J Allergy Clin Immunol 1994;94(4):708-15 (Pubitemid 24326152
    • (1994) Journal of Allergy and Clinical Immunology , vol.94 , Issue.4 , pp. 708-715
    • Meltzer, E.O.1    Orgel, H.A.2    Rogenes, P.R.3    Field, E.A.4
  • 73
    • 0025913662 scopus 로고
    • Immunotherapy decreases antigeninduced eosinophil cell migration into the nasal cavity
    • Furin MJ, Norman PS, Creticos PS, et al. Immunotherapy decreases antigeninduced eosinophil cell migration into the nasal cavity. J Allergy Clin Immunol 1991;88(1):27-32
    • (1991) J Allergy Clin Immunol , vol.88 , Issue.1 , pp. 27-32
    • Furin, M.J.1    Norman, P.S.2    Creticos, P.S.3
  • 74
    • 0029302676 scopus 로고
    • Changes in nasal metachromatic cells during allergen immunotherapy in children
    • Cengizlier R, Saraclar Y, Adalioglu C, Tuncer A. Changes in nasal metachromatic cells during allergen immunotherapy in children. Allergol Immunopathol (Madr) 1995;23(3):111-16
    • (1995) Allergol Immunopathol (Madr , vol.23 , Issue.3 , pp. 111-116
    • Cengizlier, R.1    Saraclar, Y.2    Adalioglu, C.3    Tuncer, A.4
  • 75
    • 0026093155 scopus 로고
    • Changes in nasal metachromatic cells during allergen immunotherapy
    • Otsuka H, Mezawa A, Ohnishi M, et al. Changes in nasal metachromatic cells during allergen immunotherapy. Clin Exp Allergy 1991;21(1):115-19
    • (1991) Clin Exp Allergy , vol.21 , Issue.1 , pp. 115-119
    • Otsuka, H.1    Mezawa, A.2    Ohnishi, M.3
  • 76
    • 9644291636 scopus 로고    scopus 로고
    • Adjuvants for allergen immunotherapy: Experimental results and clinical perspectives
    • DOI 10.1097/00130832-200412000-00012
    • Francis JN, Durham SR. Adjuvants for allergen immunotherapy: Experimental results and clinical perspectives. Curr Opin Allergy Clin Immunol 2004;4(6):543-8 (Pubitemid 39573730
    • (2004) Current Opinion in Allergy and Clinical Immunology , vol.4 , Issue.6 , pp. 543-548
    • Francis, J.N.1    Durham, S.R.2
  • 77
    • 67649985897 scopus 로고    scopus 로고
    • Quantitative immunohistochemistry by measuring chromogen signal strength using a C# written program
    • Javanmard SH, Moeiny A. Quantitative immunohistochemistry by measuring chromogen signal strength using a C# written program. J Res Med Sci 2009;14(3):201-3
    • (2009) J Res Med Sci , vol.14 , Issue.3 , pp. 201-203
    • Javanmard, S.H.1    Moeiny, A.2
  • 78
    • 0034000849 scopus 로고    scopus 로고
    • Quantitative immunohistochemistry by measuring cumulative signal strength using commercially available software photoshop and matlab
    • Matkowskyj KA, Schonfeld D, Benya RV. Quantitative immunohistochemistry by measuring cumulative signal strength using commercially available software photoshop and matlab. J Histochem Cytochem 2000;48(2):303-12
    • (2000) J Histochem Cytochem , vol.48 , Issue.2 , pp. 303-312
    • Matkowskyj, K.A.1    Schonfeld, D.2    Benya, R.V.3
  • 79
    • 79954500285 scopus 로고    scopus 로고
    • Improved structure function and compatibility for cellprofiler: Modular high-Throughput image analysis software
    • Kamentsky L, Jones TR, Fraser A, et al. Improved structure, function and compatibility for CellProfiler: Modular high-Throughput image analysis software. Bioinformatics 2011;27(8):1179-80
    • (2011) Bioinformatics , vol.27 , Issue.8 , pp. 1179-1180
    • Kamentsky, L.1    Jones, T.R.2    Fraser, A.3
  • 80
    • 33845792555 scopus 로고    scopus 로고
    • CellProfiler: Image analysis software for identifying and quantifying cell phenotypes
    • Carpenter AE, Jones TR, Lamprecht MR, et al. CellProfiler: Image analysis software for identifying and quantifying cell phenotypes. Genome Biol 2006;7(10):R100
    • (2006) Genome Biol , vol.7 , Issue.10
    • Carpenter, A.E.1    Jones, T.R.2    Lamprecht, M.R.3
  • 81
    • 0001304219 scopus 로고
    • In situ hybridization
    • Springer, New York
    • Langdale JA. In situ hybridization. In: The maize handbook. Springer, New York; 1994. p. 165-80
    • (1994) The Maize Handbook , pp. 165-180
    • Langdale, J.A.1
  • 82
    • 74049111634 scopus 로고
    • Cell-specific photosynthetic gene expression in maize determined using cell separation techniques and hybridization in situ
    • Martineau B, Taylor WC. Cell-specific photosynthetic gene expression in maize determined using cell separation techniques and hybridization in situ. Plant Physiol 1986;82(2):613-18
    • (1986) Plant Physiol , vol.82 , Issue.2 , pp. 613-618
    • Martineau, B.1    Taylor, W.C.2
  • 83
    • 0026603643 scopus 로고
    • Cytokine messenger RNA expression for IL-3, IL-4, IL-5, and granulocyte/ macrophage-colony-stimulating factor in the nasal mucosa after local allergen provocation: Relationship to tissue eosinophilia
    • Durham SR, Ying S, Varney VA, et al. Cytokine messenger RNA expression for IL-3, IL-4, IL-5, and granulocyte/ macrophage-colony-stimulating factor in the nasal mucosa after local allergen provocation: Relationship to tissue eosinophilia. J Immunol 1992;148(8):2390-4
    • (1992) J Immunol , vol.148 , Issue.8 , pp. 2390-2394
    • Durham, S.R.1    Ying, S.2    Varney, V.A.3
  • 85
    • 0036195516 scopus 로고    scopus 로고
    • Improvement of non-radioactive in situ hybridization in human airway tissues: Use of PCR-generated templates for synthesis of probes and an antibody sandwich technique for detection of hybridization
    • Divjak M, Glare EM, Walters EH. Improvement of non-radioactive in situ hybridization in human airway tissues: Use of PCR-generated templates for synthesis of probes and an antibody sandwich technique for detection of hybridization. J Histochem Cytochem 2002;50(4):541-8 (Pubitemid 34250593
    • (2002) Journal of Histochemistry and Cytochemistry , vol.50 , Issue.4 , pp. 541-548
    • Divjak, M.1    Glare, E.M.2    Walters, E.H.3
  • 87
    • 7444228630 scopus 로고    scopus 로고
    • Inflammatory mediators in allergic rhinitis
    • Suppl
    • Gelfand EW. Inflammatory mediators in allergic rhinitis. J Allergy Clin Immunol 2004;114(5 Suppl):S135-8
    • (2004) J Allergy Clin Immunol , vol.114 , Issue.5
    • Gelfand, E.W.1
  • 90
    • 77956858214 scopus 로고    scopus 로고
    • Temporal relationship between primary and motile ciliogenesis in airway epithelial cells
    • Jain R, Pan J, Driscoll JA, et al. Temporal relationship between primary and motile ciliogenesis in airway epithelial cells. Am J Respir Cell Mol Biol 2010;43(6):731-9
    • (2010) Am J Respir Cell Mol Biol , vol.43 , Issue.6 , pp. 731-739
    • Jain, R.1    Pan, J.2    Driscoll, J.A.3
  • 91
    • 34250660588 scopus 로고    scopus 로고
    • Physiological 3D tissue model of the airway wall and mucosa
    • Choe MM, Tomei AA, Swartz MA. Physiological 3D tissue model of the airway wall and mucosa. Nat Protoc 2006;1(1):357-62
    • (2006) Nat Protoc , vol.1 , Issue.1 , pp. 357-362
    • Choe, M.M.1    Tomei, A.A.2    Swartz, M.A.3
  • 92
    • 79960861882 scopus 로고    scopus 로고
    • Human bronchial epithelial cells differentiate to 3D glandular acini on basement membrane matrix
    • Wu X, Peters-Hall JR, Bose S, et al. Human bronchial epithelial cells differentiate to 3D glandular acini on basement membrane matrix. Am J Respir Cell Mol Biol 2011;44(6):914-21
    • (2011) Am J Respir Cell Mol Biol , vol.44 , Issue.6 , pp. 914-921
    • Wu, X.1    Peters-Hall, J.R.2    Bose, S.3
  • 93
    • 84880874906 scopus 로고    scopus 로고
    • An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung
    • Klein SG, Serchi T, Hoffmann L, et al. An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung. Part Fibre Toxicol 2013;10(1):31
    • (2013) Part Fibre Toxicol , vol.10 , Issue.1 , pp. 31
    • Klein, S.G.1    Serchi, T.2    Hoffmann, L.3
  • 94
    • 0033612644 scopus 로고    scopus 로고
    • Reactive oxygen intermediate-release of fibre-exposed monocytes increases inflammatory cytokine-mrna level, protein tyrosine kinase and nf-kappab activity in co-cultured bronchial epithelial cells (beas-2b
    • Drumm K, Messner C, Kienast K. Reactive oxygen intermediate-release of fibre-exposed monocytes increases inflammatory cytokine-mRNA level, protein tyrosine kinase and NF-kappaB activity in co-cultured bronchial epithelial cells (BEAS-2B). Eur J Med Res 1999;4(7):257-63
    • (1999) Eur J Med Res , vol.4 , Issue.7 , pp. 257-263
    • Drumm, K.1    Messner, C.2    Kienast, K.3
  • 95
    • 0031887121 scopus 로고    scopus 로고
    • Human bronchial epithelial cells modulate collagen gel contraction by fibroblasts
    • Mio T, Liu XD, Adachi Y, et al. Human bronchial epithelial cells modulate collagen gel contraction by fibroblasts. Am J Physiol 1998;274(1 Pt 1):L119-26
    • (1998) Am J Physiol , vol.274 , Issue.1 PART 1
    • Mio, T.1    Liu, X.D.2    Adachi, Y.3
  • 96
    • 84857189418 scopus 로고    scopus 로고
    • Oxidative stress induces unfolding protein response and inflammation in nasal polyposis
    • Jeanson L, Kelly M, Coste A, et al. Oxidative stress induces unfolding protein response and inflammation in nasal polyposis. Allergy 2012;67(3):403-12
    • (2012) Allergy , vol.67 , Issue.3 , pp. 403-412
    • Jeanson, L.1    Kelly, M.2    Coste, A.3
  • 97
    • 84899629396 scopus 로고    scopus 로고
    • Interleukin-4 and interleukin-13 compromise the sinonasal epithelial barrier and perturb intercellular junction protein expression
    • Epub ahead of print]
    • Wise SK, Laury AM, Katz EH, et al. Interleukin-4 and interleukin-13 compromise the sinonasal epithelial barrier and perturb intercellular junction protein expression. Int Allergy Rhinol 2014. [Epub ahead of print]
    • (2014) Int Allergy Rhinol
    • Wise, S.K.1    Laury, A.M.2    Katz, E.H.3
  • 98
    • 75749090787 scopus 로고    scopus 로고
    • Expression of splunc1 protein in nasal polyp epithelial cells in air-liquid interface culture treated with il-13
    • Yeh TH, Lee SY, Hsu WC. Expression of SPLUNC1 protein in nasal polyp epithelial cells in air-liquid interface culture treated with IL-13. Am J Rhinol Allergy 2010;24(1):17-20
    • (2010) Am J Rhinol Allergy , vol.24 , Issue.1 , pp. 17-20
    • Yeh, T.H.1    Lee, S.Y.2    Hsu, W.C.3
  • 99
    • 33748463005 scopus 로고    scopus 로고
    • Extracellular matrix remodeling by dynamic strain in a three-dimensional tissue-engineered human airway wall model
    • DOI 10.1165/rcmb.2005-0443OC
    • Choe MM, Sporn PH, Swartz MA. Extracellular matrix remodeling by dynamic strain in a three-dimensional tissue-engineered human airway wall model. Am J Respir Cell Mol Biol 2006;35(3):306-13 (Pubitemid 44353398
    • (2006) American Journal of Respiratory Cell and Molecular Biology , vol.35 , Issue.3 , pp. 306-313
    • Choe, M.M.1    Sporn, P.H.S.2    Swartz, M.A.3
  • 100
    • 0032903716 scopus 로고    scopus 로고
    • Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: An in vitro co-culture model of airway remodeling in asthma
    • Zhang S, Smartt H, Holgate ST, Roche WR. Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: An in vitro co-culture model of airway remodeling in asthma. Lab Invest 1999;79(4):395-405 (Pubitemid 29190429
    • (1999) Laboratory Investigation , vol.79 , Issue.4 , pp. 395-405
    • Zhang, S.1    Smartt, H.2    Holgate, S.T.3    Roche, W.R.4
  • 104
    • 77952783111 scopus 로고    scopus 로고
    • Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients
    • Vijayanand P, Durkin K, Hartmann G, et al. Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients. J Immunol 2010;184(8):4568-74
    • (2010) J Immunol , vol.184 , Issue.8 , pp. 4568-4574
    • Vijayanand, P.1    Durkin, K.2    Hartmann, G.3
  • 105
    • 58149132300 scopus 로고    scopus 로고
    • Expression of osteopontin in chronic rhinosinusitis with and without nasal polyps
    • Lu X, Zhang XH, Wang H, et al. Expression of osteopontin in chronic rhinosinusitis with and without nasal polyps. Allergy 2009;64(1):104-11
    • (2009) Allergy , vol.64 , Issue.1 , pp. 104-111
    • Lu, X.1    Zhang, X.H.2    Wang, H.3
  • 106
    • 38149126990 scopus 로고    scopus 로고
    • Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps
    • Patou J, Gevaert P, Van Zele T, et al. Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps. J Allergy Clin Immunol 2008;121(1):110-15
    • (2008) J Allergy Clin Immunol , vol.121 , Issue.1 , pp. 110-115
    • Patou, J.1    Gevaert, P.2    Van Zele, T.3
  • 109
    • 81355146382 scopus 로고    scopus 로고
    • From 3d cell culture to organs-on-chips
    • Huh D, Hamilton GA, Ingber DE. From 3D cell culture to organs-on-chips. Trends Cell Biol 2011;21(12):745-54
    • (2011) Trends Cell Biol , vol.21 , Issue.12 , pp. 745-754
    • Huh, D.1    Hamilton, G.A.2    Ingber, D.E.3
  • 110
    • 77954038080 scopus 로고    scopus 로고
    • Reconstituting organ-level lung functions on a chip
    • Huh D, Matthews BD, Mammoto A, et al. Reconstituting organ-level lung functions on a chip. Science 2010;328(5986):1662-8
    • (2010) Science , vol.328 , Issue.5986 , pp. 1662-1668
    • Huh, D.1    Matthews, B.D.2    Mammoto, A.3
  • 111
    • 37649009647 scopus 로고    scopus 로고
    • Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems
    • Huh D, Fujioka H, Tung YC, et al. Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems. Proc Natl Acad Sci USA 2007;104(48):18886-91
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.48 , pp. 18886-18891
    • Huh, D.1    Fujioka, H.2    Tung, Y.C.3
  • 112
    • 70549099703 scopus 로고    scopus 로고
    • An open-Access microfluidic model for lung-specific functional studies at an air-liquid interface
    • Nalayanda DD, Puleo C, Fulton WB, et al. An open-Access microfluidic model for lung-specific functional studies at an air-liquid interface. Biomed Microdevices 2009;11(5):1081-9
    • (2009) Biomed Microdevices , vol.11 , Issue.5 , pp. 1081-1089
    • Nalayanda, D.D.1    Puleo, C.2    Fulton, W.B.3
  • 113
    • 80053100399 scopus 로고    scopus 로고
    • Scientific process pharmacology and drug discovery
    • Trist DG. Scientific process, pharmacology and drug discovery. Curr Opin Pharmacol 2011;11(5):528-33
    • (2011) Curr Opin Pharmacol , vol.11 , Issue.5 , pp. 528-533
    • Trist, D.G.1
  • 114
    • 73449107200 scopus 로고    scopus 로고
    • The future of drug development: Advancing clinical trial design
    • Orloff J, Douglas F, Pinheiro J, et al. The future of drug development: Advancing clinical trial design. Nat Rev Drug Discov 2009;8(12):949-57
    • (2009) Nat Rev Drug Discov , vol.8 , Issue.12 , pp. 949-957
    • Orloff, J.1    Douglas, F.2    Pinheiro, J.3
  • 115
    • 38749113369 scopus 로고    scopus 로고
    • Methods used in clinical development of novel anti-Asthma therapies
    • DOI 10.1016/j.rmed.2007.10.018, PII S0954611107004416
    • Diamant Z, Boot D, Kamerling I, Bjermer L. Methods used in clinical development of novel anti-Asthma therapies. Respir Med 2008;102(3):332-8 (Pubitemid 351179985
    • (2008) Respiratory Medicine , vol.102 , Issue.3 , pp. 332-338
    • Diamant, Z.1    Boot, D.2    Kamerling, I.3    Bjermer, L.4
  • 116
    • 79953652383 scopus 로고    scopus 로고
    • Assessment of problematic severe asthma in children
    • Lodrup Carlsen KC, Hedlin G, Bush A, et al. Assessment of problematic severe asthma in children. Eur Respir J 2011;37(2):432-40
    • (2011) Eur Respir J , vol.37 , Issue.2 , pp. 432-440
    • Lodrup Carlsen, K.C.1    Hedlin, G.2    Bush, A.3
  • 117
    • 84879105693 scopus 로고    scopus 로고
    • Stratified approaches to the treatment of asthma
    • Holgate ST. Stratified approaches to the treatment of asthma. Br J Clin Pharmacol 2013;76(2):277-91
    • (2013) Br J Clin Pharmacol , vol.76 , Issue.2 , pp. 277-291
    • Holgate, S.T.1
  • 118
    • 84875796596 scopus 로고    scopus 로고
    • Evaluation of nasal epithelium sampling as a tool in the preclinical development of siRNA-based therapeutics for asthma
    • Healey GD, Evans N, Hopkin JM, et al. Evaluation of nasal epithelium sampling as a tool in the preclinical development of siRNA-based therapeutics for asthma. J Cell Mol Med 2013;17(3):356-64
    • (2013) J Cell Mol Med , vol.17 , Issue.3 , pp. 356-364
    • Healey, G.D.1    Evans, N.2    Hopkin, J.M.3
  • 119
    • 84857880134 scopus 로고    scopus 로고
    • Comparison of nasal and bronchial epithelial cells obtained from patients with COPD
    • Comer DM, Elborn JS, Ennis M. Comparison of nasal and bronchial epithelial cells obtained from patients with COPD. PLoS One 2012;7(3):e32924
    • (2012) PLoS One , vol.7 , Issue.3
    • Comer, D.M.1    Elborn, J.S.2    Ennis, M.3
  • 120
    • 36549028855 scopus 로고    scopus 로고
    • Pathologic similarities and differences between asthma and chronic obstructive pulmonary disease
    • DOI 10.1097/MCP.0b013e3282f19846, PII 0006319820080100000007
    • Mauad T, Dolhnikoff M. Pathologic similarities and differences between asthma and chronic obstructive pulmonary disease. Curr Opin Pulm Med 2008;14(1):31-8 (Pubitemid 350191036
    • (2008) Current Opinion in Pulmonary Medicine , vol.14 , Issue.1 , pp. 31-38
    • Mauad, T.1    Dolhnikoff, M.2
  • 122
    • 0034109665 scopus 로고    scopus 로고
    • Airway smooth muscle cells: Contributing to and regulating airway mucosal inflammation
    • Chung KF. Airway smooth muscle cells: Contributing to and regulating airway mucosal inflammation? Eur Respir J 2000;15(5):961-8
    • (2000) Eur Respir J , vol.15 , Issue.5 , pp. 961-968
    • Chung, K.F.1
  • 123
    • 84895511218 scopus 로고    scopus 로고
    • Brain natriuretic peptide protects against hyperreactivity of human asthmatic airway smooth muscle via an epithelial cell dependent mechanism
    • Calzetta L, Passeri D, Kanabar V, et al. Brain natriuretic peptide protects against hyperreactivity of human asthmatic airway smooth muscle via an epithelial cell dependent mechanism. Am J Respir Cell Mol Biol 2014;50(3):493-501
    • (2014) Am J Respir Cell Mol Biol , vol.50 , Issue.3 , pp. 493-501
    • Calzetta, L.1    Passeri, D.2    Kanabar, V.3
  • 124
    • 84882399041 scopus 로고    scopus 로고
    • Effect of the mixed phosphodiesterase 3/4 inhibitor RPL554 on human isolated bronchial smooth muscle tone
    • Calzetta L, Page CP, Spina D, et al. Effect of the mixed phosphodiesterase 3/4 inhibitor RPL554 on human isolated bronchial smooth muscle tone. J Pharmacol Exp Ther 2013;346(3):414-23
    • (2013) J Pharmacol Exp Ther , vol.346 , Issue.3 , pp. 414-423
    • Calzetta, L.1    Page, C.P.2    Spina, D.3
  • 125
    • 84873178074 scopus 로고    scopus 로고
    • Epithelial-smooth muscle cooperation is needed for brain natriuretic peptidedependent bronchorelaxant activity
    • Matera MG, Calzetta L, Passeri D, et al. Epithelial-smooth muscle cooperation is needed for brain natriuretic peptidedependent bronchorelaxant activity. Pulm Pharmacol Ther 2013;26(1):156-7
    • (2013) Pulm Pharmacol Ther , vol.26 , Issue.1 , pp. 156-157
    • Matera, M.G.1    Calzetta, L.2    Passeri, D.3
  • 126
    • 84856404019 scopus 로고    scopus 로고
    • Pharmacological characterization of adenosine receptors on isolated human bronchi
    • Calzetta L, Spina D, Cazzola M, et al. Pharmacological characterization of adenosine receptors on isolated human bronchi. Am J Respir Cell Mol Biol 2011;45(6):1222-31
    • (2011) Am J Respir Cell Mol Biol , vol.45 , Issue.6 , pp. 1222-1231
    • Calzetta, L.1    Spina, D.2    Cazzola, M.3
  • 127
    • 79960926521 scopus 로고    scopus 로고
    • Epithelium integrity is crucial for the relaxant activity of brain natriuretic peptide in human isolated bronchi
    • Matera MG, Calzetta L, Passeri D, et al. Epithelium integrity is crucial for the relaxant activity of brain natriuretic peptide in human isolated bronchi. Br J Pharmacol 2011;163(8):1740-54
    • (2011) Br J Pharmacol , vol.163 , Issue.8 , pp. 1740-1754
    • Matera, M.G.1    Calzetta, L.2    Passeri, D.3
  • 128
    • 71249112362 scopus 로고    scopus 로고
    • Relaxant effect of brain natriuretic peptide in nonsensitized and passively sensitized isolated human bronchi
    • Matera MG, Calzetta L, Parascandolo V, et al. Relaxant effect of brain natriuretic peptide in nonsensitized and passively sensitized isolated human bronchi. Pulm Pharmacol Ther 2009;22(6):478-82
    • (2009) Pulm Pharmacol Ther , vol.22 , Issue.6 , pp. 478-482
    • Matera, M.G.1    Calzetta, L.2    Parascandolo, V.3
  • 129
    • 26244458211 scopus 로고    scopus 로고
    • Immune sensitization of equine bronchus: Glutathione, IL-1beta expression and tissue responsiveness
    • Matera MG, Calzetta L, Peli A, et al. Immune sensitization of equine bronchus: Glutathione, IL-1beta expression and tissue responsiveness. Respir Res 2005;6:104
    • (2005) Respir Res , vol.6 , pp. 104
    • Matera, M.G.1    Calzetta, L.2    Peli, A.3
  • 130
    • 0035689598 scopus 로고    scopus 로고
    • Auxotonic contractile responses of rat tracheal and bronchial airway smooth muscle
    • DOI 10.1006/pupt.2001.0308
    • van Lunteren E, Moyer M. Auxotonic contractile responses of rat tracheal and bronchial airway smooth muscle. Pulm Pharmacol Ther 2001;14(6):443-53 (Pubitemid 34081696
    • (2001) Pulmonary Pharmacology and Therapeutics , vol.14 , Issue.6 , pp. 443-453
    • Van Lunteren, E.1    Moyer, M.2


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