Reduced nasal IL-10 and enhanced TNFα responses during rhinovirus and RSV-induced upper respiratory tract infection in atopic and non-atopic infants

Journal of Medical Virology

Volumn 75, Issue 2, 2005, Pages 348-357

  Van Benten, I J ^a   Van Drunen, C M ^a,b   Koevoet, J L M ^a   Koopman, L P ^a   Hop, W C J ^a   Osterhaus, A D M E ^a   Neijens, H J ^a   Fokkens, W J ^a,b  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Cytokines; Infant; Nose; Respiratory infection; Rhinovirus; RSV

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 18; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ATOPY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMETRY; FEMALE; HUMAN; IMMUNE SYSTEM; IMMUNOHISTOCHEMISTRY; INFANT; MALE; MATURATION; NASAL BIOPSY; PRESCHOOL CHILD; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RHINOVIRUS; TH1 CELL; TH2 CELL; UPPER RESPIRATORY TRACT INFECTION;

CHILD, PRESCHOOL; HUMANS; HYPERSENSITIVITY, IMMEDIATE; INFANT; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKINS; NASAL MUCOSA; PICORNAVIRIDAE INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY TRACT INFECTIONS; RHINOVIRUS; SEVERITY OF ILLNESS INDEX; TUMOR NECROSIS FACTOR-ALPHA;

RESPIRATORY SYNCYTIAL VIRUS; RHINOVIRUS; RICE STRIPE VIRUS; SYNCYTIAL VIRUS;

EID: 11144235132     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmv.20277     Document Type: Article

References (52)

1. Akdis CA, Blaser K. 2001. Mechanisms of interleukin-10-mediated immune suppression. Immunology 103:131-136.
2. Bartz H, Buning-Pfaue F, Turkel O, Schauer U. 2002. Respiratory syncytial virus induces prostaglandin E2, IL-10 and IL-11 generation in antigen presenting cells. Clin Exp Immunol 129:438-445.
3. Blomqvist S, Roivainen M, Puhakka T, Kleemola M, Hovi T. 2002. Virological and serological analysis of rhinovirus infections during the first two years of life in a cohort of children. J Med Virol 66:263-268.
4. Bont L, Heijnen CJ, Kavelaars A, van Aalderen WM, Brus F, Draaisma JT, Geelen SM, Kimpen JL. 2000. Monocyte IL-10 production during respiratory syncytial virus bronchiolitis is associated with recurrent wheezing in a one-year follow-up study. Am J Respir Grit Care Med 161:1518-1523.
5. Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
6. Brandenburg AH, Groen J, van Steensel-Moll HA, Claas EC, Rothbarth PH, Neijens HJ, Osterhaus AD. 1997. Respiratory syncytial virus specific serum antibodies in infants under six months of age: Limited serological response upon infection. J Med Virol 52:97-104.
7. Braunstahl GJ, Overbeek SE, Fokkens WJ, Kleinjan A, McEuen AR, Walls AF, Hoogsteden HC, Prins JB. 2001. Segmental bronchoprovocation in allergic rhinitis patients affects mast cell and basophil numbers in nasal and bronchial mucosa. Am J Respir Crit Care Med 164:858-865.
8. Chalmers IM, Janossy G, Contreras M, Navarrete C. 1998. Intracellular cytokine profile of cord and adult blood lymphocytes. Blood 92:11-18.
9. Cohen SB, Perez-Cruz I, Fallen P, Gluckman E, Madrigal JA. 1999. Analysis of the cytokine production by cord and adult blood. Hum Immunol 60:331-336.
10. Corne JM, Lau L, Scott SJ, Davies R, Johnston SL, Howarth PH. 2001. The relationship between atopic status and IL-10 nasal lavage levels in the acute and persistent inflammatory response to upper respiratory tract infection. Am J Respir Crit Care Med 163:1101-1107.
11. Denny FW, Jr. 1995. The clinical impact of human respiratory virus infections. Am J Respir Crit Care Med 152:S4-S12.
12. Feng X, Yau D, Holbrook C, Reder AT. 2002. Type I interferons inhibit interleukin-10 production in activated human monocytes and stimulate IL-10 in T cells: Implications for Th1-mediated diseases. J Interferon Cytokine Res 22:311-319.
13. Garofalo R, Chheda S, Mei F, Palkowetz KH, Rudloff HE, Schmalstieg FC, Rassin DK, Goldman AS. 1995. Interleukin-10 in human milk. Pediatr Res 37:444-449.
14. Godthelp T, Holm AF, Fokkens WJ, Doornenbal P, Mulder PG, Hoefsmit EC, Kleinjan A, Prens EP, Rijntjes E. 1996. Dynamics of nasal eosinophils in response to a nonnatural allergen challenge in patients with allergic rhinitis and control subjects: A biopsy and brush study. J Allergy Clin Immunol 97:800-811.
15. Groux H. 2001. An overview of regulatory T cells. Microbes Infect 3:883-889.
16. Kaiser L, Fritz RS, Straus SE, Gubareva L, Hayden FG. 2001. Symptom pathogenesis during acute influenza: Interleukin-6 and other cytokine responses. J Med Virol 64:262-268.
17. Koopman LP, Van Benten IJ, De waal L, Fokkens WJ, Osterhaus ADME, Neijens HJ. 2000. Virus mediated allergy (Vigall)-study. Study design and clinical results 1 year follow-up. Am J Respiratory Crit Care Med 161:A347.
18. Lakwijk N, Van Strien RT, Doekes G, Brunekreef B, Gerritsen J. 1998. Validation of a screening questionnaire for atopy with serum IgE tests in a population of pregnant Dutch women. Clin Exp Allergy 28:454-458.
19. Langrish CL, Buddle JC, Thrasher AJ, Goldblatt D. 2002. Neonatal dendritic cells are intrinsically biased against Th-1 immune responses. Clin Exp Immunol 128:118-123.
20. Lee SM, Suen Y, Chang L, Bruner V, Qian J, Indes J, Knoppel E, van de Yen C, Cairo MS. 1996. Decreased interleukin-12 (IL-12) from activated cord versus adult peripheral blood mononuclear cells and upregulation of Interferon- gamma, natural killer, and lymphokine-activated killer activity by IL-12 in cord blood mononuclear cells. Blood 88:945-954.
21. Levings MK, Roncarolo MG. 2000. T-regulatory 1 cells: A novel subset of CD4 T cells with immunoregulatory properties. J Allergy Clin Immunol 106:S109-S112.
22. Makela MJ, Puhakka T, Ruuskanen O, Leinonen M, Saikku P, Kimpimaki M, Blomqvist S, Hyypia T, Arstila P. 1998. Viruses and bacteria in the etiology of the common cold. J Clin Microbiol 36:539-542.
23. Marshall JD, Aste-Amezaga M, Chehimi SS, Murphy M, Olsen H, Trinchieri G. 1999. Regulation of human IL-18 mRNA expression. Clin Immunol 90:15-21.
24. Morrison DF, Foss DL, Murtaugh MP. 2000. Interleukin-10 gene therapy-mediated amelioration of bacterial pneumonia. Infect Immun 68:4752-4758.
25. Moulin F, Raymond J, Iniguez JL, Ravilly S, Lebon P, Gendrel D. 1996. Serum alpha-interferon in lower respiratory tract infections of children. Pediatr Infect Dis J 15:883-886.
26. Noah TL, Henderson FW, Wortman IA, Devlin RB, Handy J, Koren HS, Becker S. 1995. Nasal cytokine production in viral acute upper respiratory infection of childhood. J Infect Dis 171:584-592.
27. Opal SM, DePalo VA. 2000. Anti-inflammatory cytokines [see comments]. Chest 117:1162-1172.
28. Papadopoulos NG, Stanciu LA, Papi A, Holgate ST, Johnston SL. 2002. A defective type 1 response to rhinovirus in atopic asthma. Thorax 57:328-332.
29. Piccinni MP. 2002. T-cell cytokines in pregnancy. Am J Reprod Immunol 47:289-294.
30. Pitkaranta A, Arruda E, Malmberg H, Hayden FG. 1997. Detection of rhinovirus in sinus brushings of patients with acute community-acquired sinusitis by reverse transcription-PCR. J Clin Microbiol 35:1791-1793.
31. Prescott SL, Macaubas C, Holt BJ, Smallacombe TB, Loh R, Sly PD, Holt PG. 1998. Transplacental priming of the human immune system to environmental allergens: Universal skewing of initial T cell responses toward the Th2 cytokine profile. J Immunol 160:4730-4737.
32. Rainsford E, Reen DJ. 2002. Interleukin 10, produced in abundance by human newborn T cells, may be the regulator of increased tolerance associated with cord blood stem cell transplantation. Br J Haematol 116:702-709.
33. Ribeiro-do-Couto LM, Boeije LC, Kroon JS, Hooibrink B, Breur-Vriesendorp BS, Aarden LA, Boog CJ. 2001. High IL-13 production by human neonatal T cells: Neonate immune system regulator? Eur J Immunol 31:3394-3402.
34. Rothbarth PH, Habova JJ, Masurel N. 1988. Rapid diagnosis of infections caused by respiratory syncytial virus. Infection 16:252.
35. Sareneva T, Matikainen S, Kurimoto M, Julkunen I. 1998. Influenza A virus-induced IFN-alpha/beta and IL-18 synergistically enhance IFN-gamma gene expression in human T cells. J Immunol 160:6032-6038.
36. Sautois B, Fillet G, Beguin Y. 1997. Comparative cytokine production by in vitro stimulated mononucleated cells from cord blood and adult blood. Exp Hematol 25:103-108.
37. Schandene L, Alonso-Vega C, Willems F, Gerard C, Delvaux A, Velu T, Devos R, de Boer M, Goldman M. 1994. B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10. J Immunol 152:4368-4374.
38. Schultz-Cherry S, Hinshaw VS. 1996. Influenza virus neuraminidase activates latent transforming growth factor beta. J Virol 70:8624-8629.
39. Sedgwick JD, Riminton DS, Cyster JG, Korner H. 2000. Tumor necrosis factor: A master-regulator of leukocyte movement. Immunol Today 21:110-113.
40. Shibuya K, Robinson D, Zonin F, Hartley SB, Macatonia SE, Somoza C, Hunter CA, Murphy KM, O'Garra A. 1998. IL-1 alpha and TNF-alpha are required for IL-12-induced development of Th1 cells producing high levels of IFN-gamma in BALB/c but not C57BL/6 mice. J Immunol 160:1708-1716.
41. Shin DI, Banning U, Kim YM, Verheyen J, Hannen M, Bonig H, Korholz D. 1999. Interleukin 10 inhibits TNF-alpha production in human monocytes independently of interleukin 12 and interleukin 1 beta. Immunol Invest 28:165-175.
42. Strachan DP. 2000. Family size, infection and atopy: The first decade of the "hygiene hypothesis". Thorax 55(Suppl 1):S2-S10.
43. Suberville S, Bellocq A, Peguillet I, Lantz O, Stordeur P, Fouqueray B, Baud L. 2001. Transforming growth factor-beta inhibits interleukin-10 synthesis by human monocytic cells. Eur Cytokine Netw 12:141-146.
44. Sung RY, Hui SH, Wong CK, Lam CW, Yin J. 2001. A comparison of cytokine responses in respiratory syncytial virus and influenza A infections in infants. Eur J Pediatr 160:117-122.
45. Tracey KJ, Cerami A. 1993. Tumor necrosis factor, other cytokines and disease. Annu Rev Cell Biol 9:317-343.
46. Ukkonen P, Hovi T, von Bonsdorff CH, Saikku P, Penttinen K. 1984. Age-specific prevalence of complement-fixing antibodies to sixteen viral antigens: A computer analysis of 58,500 patients covering a period of eight years. J Med Virol 13:131-148.
47. van den Biggelaar AH, van Ree R, Rodrigues LC, Lell B, Deelder AM, Kremsner PG, Yazdanbakhsh M. 2000. Decreased atopy in children infected with Schistosoma haematobium: A role for parasite-induced interleukin-10. Lancet 356:1723-1727.
48. Vesa S, Kleemola M, Blomqvist S, Takala A, Kilpi T, Hovi T. 2001. Epidemiology of documented viral respiratory infections and acute otitis media in a cohort of children followed from two to twenty-four months of age. Pediatr Infect Dis J 20:574-581.
49. Wakkach A, Cottrez F, Groux H. 2000. Can interleukin-10 be used as a true immunoregulatory cytokine? Eur Cytokine Netw 11:153-160.
50. Williams HC, Forsdyke H, Boodoo G, Hay RJ, Burney PG. 1995. A protocol for recording the sign of flexural dermatitis in children. Br J Dermatol 133:941-949.
51. Yazdanbakhsh M, Kremsner PG, van Ree R. 2002. Allergy, parasites, and the hygiene hypothesis. Science 296:490-494.
52. Zhao Y, Dai ZP, Lv P, Gao XM. 2002. Phenotypic and functional analysis of human T lymphocytes in early second- and third-trimester fetuses. Clin Exp Immunol 129:302-308.