Acetylcholinesterase inhibitors with photoswitchable inhibition of β-amyloid aggregation

ACS Chemical Neuroscience

Volumn 5, Issue 5, 2014, Pages 377-389

  Chen, Xinyu ^a,c   Wehle, Sarah ^c   Kuzmanovic, Natascha ^b   Merget, Benjamin ^c   Holzgrabe, Ulrike ^c   König, Burkhard ^b   Sotriffer, Christoph A ^c   Decker, Michael ^a,c  

^a Institut für Pharmazie   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

1,2 dithienylethene; Alzheimer's disease; beta amyloid aggregation; cholinesterase inhibitors; photochromism; tacrine

Indexed keywords

AMYLOID BETA PROTEIN; CARBON DIOXIDE; CARBOXYLIC ACID DERIVATIVE; CHOLINESTERASE INHIBITOR; ETHYLENEDIAMINE; TACRINE DERIVATIVE; PHOTOSENSITIZING AGENT; PROTEIN AGGREGATE;

ACYLATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL INTERACTION; CHOLINESTERASE INHIBITION; ENTROPY; ENZYME INHIBITION; HUMAN; HYDROGEN BOND; IONIC STRENGTH; IRRADIATION; ISOMER; MOLECULAR DYNAMICS; PH; PHOTOCHEMISTRY; PHOTODEGRADATION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DETERMINATION; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; STRUCTURE ACTIVITY RELATION;

ANIMALS; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHOTOSENSITIZING AGENTS; PROTEIN AGGREGATES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84901246932     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn500016p     Document Type: Article

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