Deletion of the nuclear localization sequences and C-terminus of PTHrP impairs embryonic mammary development but also inhibits PTHrP production

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Boras Granic, Kata ^a   Dann, Pamela ^a   VanHouten, Joshua ^a   Karaplis, Andrew ^b   Wysolmerski, John ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ESTROGEN RECEPTOR; MESSENGER RNA; PARATHYROID HORMONE RELATED PROTEIN; BIOLOGICAL MARKER; NUCLEAR LOCALIZATION SIGNAL; PARATHYROID HORMONE-RELATED PROTEIN (1-84); PEPTIDE FRAGMENT;

ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST DEVELOPMENT; BREAST EPITHELIUM; CELL AGING; CELL SURVIVAL; DEVELOPMENTAL STAGE; EMBRYO; FEMALE; HISTOLOGY; KERATINOCYTE; MAMMARY GLAND; MESENCHYME; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; SEX DIFFERENCE; ANIMAL; BIOSYNTHESIS; CHEMISTRY; EMBRYOLOGY; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PROTEIN DOMAIN; SEXUAL DEVELOPMENT; TRANSGENIC MOUSE; UDDER;

ANIMALS; BIOLOGICAL MARKERS; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MAMMARY GLANDS, ANIMAL; MICE; MICE, TRANSGENIC; NUCLEAR LOCALIZATION SIGNALS; PARATHYROID HORMONE-RELATED PROTEIN; PEPTIDE FRAGMENTS; PROTEIN INTERACTION DOMAINS AND MOTIFS; SEX CHARACTERISTICS;

EID: 84901236453     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090418     Document Type: Article

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