Nuclear localization of parathyroid hormone-related peptide confers resistance to anoikis in prostate cancer cells

Endocrine-Related Cancer

Volumn 19, Issue 3, 2012, Pages 243-254

  Park, Serk In ^a   McCauley, Laurie K ^a,b  

^a UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PARATHYROID HORMONE RELATED PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANOIKIS; ARTICLE; BONE METASTASIS; CANCER CELL CULTURE; CELL NUCLEUS; CELL SURVIVAL; CONTROLLED STUDY; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; PROSTATE CANCER; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ANIMALS; ANOIKIS; BONE NEOPLASMS; CELL LINE, TUMOR; CELL NUCLEUS; GENE KNOCKDOWN TECHNIQUES; HUMANS; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PARATHYROID HORMONE-RELATED PROTEIN; PROSTATIC NEOPLASMS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84862670200     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1530/ERC-11-0278     Document Type: Article

References (33)

1. Aarts MM, Levy D, He B, Stregger S, Chen T, Richard S &Henderson JE 1999 Parathyroid hormone-related protein interacts with RNA. Journal of Biological Chemistry 274 4832-4838. (doi:10.1074/jbc.274.8.4832)
2. Amling M, Neff L, Tanaka S, Inoue D, Kuida K, Weir E, Philbrick WM, Broadus AE & Baron R 1997 Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development. Journal of Cell Biology 136 205-213. (doi:10.1083/jcb.136.1.205)
3. Bhatia V, Mula RV, Weigel NL & Falzon M 2009a Parathyroid hormone-related protein regulates cell survival pathways via integrin alpha6beta4-mediated activation of phosphatidylinositol 3-kinase/Akt signaling. Molecular Cancer Research 7 1119-1131. (doi:10.1158/ 1541-7786.MCR-08-0568)
4. Bhatia V, Saini MK & Falzon M 2009b Nuclear PTHrP targeting regulates PTHrP secretion and enhances LoVo cell growth and survival. Regulatory Peptides 158 149-155. (doi:10.1016/j.regpep.2009.07.008)
5. Deftos LJ, Barken I, Burton DW, Hoffman RM & Geller J 2005 Direct evidence that PTHrP expression promotes prostate cancer progression in bone. Biochemical and Biophysical Research Communications 327 468-472. (doi:10.1016/j.bbrc.2004.11.162)
6. Dougherty KM, Blomme EA, Koh AJ, Henderson JE, Pienta KJ, Rosol TJ & McCauley LK 1999 Parathyroid hormone-related protein as a growth regulator of prostate carcinoma. Cancer Research 59 6015-6022. (Pubitemid 30004967)
7. Downey SE, Hoyland J, Freemont AJ, Knox F, Walls J &Bundred NJ 1997 Expression of the receptor for parathyroid hormone-related protein in normal and malignant breast tissue. Journal of Pathology 183 212-217. (doi:10.1002/(SICI) 1096-9896(199710) 183:2〈212::AID-PATH920〉3.0.CO;2-O)
8. Frisch SM & Francis H 1994 Disruption of epithelial cell-matrix interactions induces apoptosis. Journal of Cell Biology 124 619-626. (doi:10.1083/jcb. 124.4.619)
9. Henderson JE, Amizuka N, Warshawsky H, Biasotto D, Lanske BM, Goltzman D & Karaplis AC 1995 Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apoptotic cell death. Molecular and Cellular Biology 15 4064-4075.
10. Hiraki A, Ueoka H, Bessho A, Segawa Y, Takigawa N, Kiura K, Eguchi K, Yoneda T, Tanimoto M & Harada M 2002 Parathyroid hormone-related protein measured at the time of first visit is an indicator of bone metastases and survival in lung carcinoma patients with hypercalcemia. Cancer 95 1706-1713. (doi:10.1002/ cncr.10828)
11. Iddon J, Bundred NJ, Hoyland J, Downey SE, Baird P, Salter D, McMahon R & Freemont AJ 2000 Expression of parathyroid hormone-related protein and its receptor in bone metastases from prostate cancer. Journal of Pathology 191 170-174. (doi:10.1002/(SICI)1096-9896 (200006)191:2〈170::AID- PATH620〉3.0.CO;2-H)
12. Iwamura M, di Sant'Agnese PA, Wu G, Benning CM, Cockett AT, Deftos LJ & Abrahamsson PA 1993 Immunohistochemical localization of parathyroid hormone-related protein in human prostate cancer. Cancer Research 53 1724-1726. (Pubitemid 23127091)
13. Jemal A, Bray F, Center MM, Ferlay J, Ward E & Forman D 2011 Global cancer statistics. CA: A Cancer Journal for Clinicians 61 69-90. (doi:10.3322/caac.20107)
14. Langley RR & Fidler IJ 2011 The seed and soil hypothesis revisited - the role of tumor-stroma interactions in metastasis to different organs. International Journal of Cancer 128 2527-2535. (doi:10.1002/ijc.26031)
15. LeRoy BE, Thudi NK, Nadella MV, Toribio RE, Tannehill-Gregg SH, van Bokhoven A, Davis D, Corn S & Rosol TJ 2006 New bone formation and osteolysis by a metastatic, highly invasive canine prostate carcinoma xenograft. Prostate 66 1213-1222. (doi:10.1002/pros.20408)
16. Li X, Koh AJ, Wang Z, Soki FN, Park SI, Pienta KJ &McCauley LK 2011 Inhibitory effects of megakaryocytic cells in prostate cancer skeletal metastasis. Journal of Bone and Mineral Research 26 125-134. (doi:10.1002/ jbmr.204)
17. Liao J & McCauley LK 2006 Skeletal metastasis: established and emerging roles of parathyroid hormone related protein (PTHrP). Cancer Metastasis Reviews 25 559-571. (Pubitemid 46074999)
18. Liao J, Li X, Koh AJ, Berry JE, Thudi N, Rosol TJ, Pienta KJ & McCauley LK 2008 Tumor expressed PTHrP facilitates prostate cancer-induced osteoblastic lesions. International Journal of Cancer 123 2267-2278. (doi:10.1002/ ijc.23602)
19. Minard ME, Ellis LM & Gallick GE 2006 Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells. Clinical & Experimental Metastasis 23 301-313. (doi:10.1007/s10585-006-9040-z)
20. Moseley JM, Kubota M, Diefenbach-Jagger H, Wettenhall RE, Kemp BE, Suva LJ, Rodda CP, Ebeling PR, Hudson PJ, Zajac JD et al. 1987 Parathyroid hormone-related protein purified from a human lung cancer cell line. PNAS 84 5048-5052. (doi:10.1073/pnas.84.14.5048)
21. Park SI, Kim SJ, McCauley LK & Gallick GE 2011a Pre-clinical mouse models of human prostate cancer and their utility in drug discovery. Current Protocols in Pharmacology 51 Chapter 14:Unit 14.15.
22. Park SI, Soki FN & McCauley LK 2011b Roles of bone marrow cells in skeletal metastases: no longer bystanders. Cancer Microenvironment 4 237-246. (doi:10.1007/s12307-011-0081-8)
23. Ratcliffe WA, Norbury S, Heath DA & Ratcliffe JG 1991 Development and validation of an immunoradiometric assay of parathyrin-related protein in unextracted plasma. Clinical Chemistry 37 678-685. (Pubitemid 21892708)
24. Sakamoto S & Kyprianou N 2010 Targeting anoikis resistance in prostate cancer metastasis. Molecular Aspects of Medicine 31 205-214. (doi:10.1016/j.mam. 2010.02.001)
25. Sakamoto S, McCann RO, Dhir R & Kyprianou N 2010 Talin1 promotes tumor invasion and metastasis via focal adhesion signaling and anoikis resistance. Cancer Research 70 1885-1895. (doi:10.1158/0008-5472.CAN-09-2833)
26. Schneider A, Kalikin LM, Mattos AC, Keller ET, Allen MJ, Pienta KJ & McCauley LK 2005 Bone turnover mediates preferential localization of prostate cancer in the skeleton. Endocrinology 146 1727-1736. (doi:10.1210/en.2004-1211)
27. Shen X, Mula RV, Evers BM & Falzon M 2007a Increased cell survival, migration, invasion, and Akt expression in PTHrP-overexpressing LoVo colon cancer cell lines. Regulatory Peptides 141 61-72. (doi:10.1016/j.regpep. 2006.12.017)
28. Shen X, Rychahou PG, Evers BM & Falzon M 2007b PTHrP increases xenograft growth and promotes integrin alpha6beta4 expression and Akt activation in colon cancer. Cancer Letters 258 241-252. (doi:10.1016/j. canlet.2007.09.010)
29. Suva LJ, Winslow GA, Wettenhall RE, Hammonds RG, Moseley JM, Diefenbach-Jagger H, Rodda CP, Kemp BE, Rodriguez H, Chen EY et al. 1987 A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression. Science 237 893-896. (doi:10.1126/science.3616618)
30. Thudi NK, Martin CK, Murahari S, Shu ST, Lanigan LG, Werbeck JL, Keller ET, McCauley LK, Pinzone JJ &Rosol TJ 2011 Dickkopf-1 (DKK-1) stimulated prostate cancer growth and metastasis and inhibited bone formation in osteoblastic bone metastases. Prostate 71 615-625. (doi:10.1002/pros.21277)
31. Toribio RE, Brown HA, Novince CM, Marlow B, Hernon K, Lanigan LG, Hildreth BE III, Werbeck JL, Shu ST, Lorch G et al. 2010 The midregion, nuclear localization sequence, and C terminus of PTHrP regulate skeletal development, hematopoiesis, and survival in mice. FASEB Journal 24 1947-1957. (doi:10.1096/fj.09-147033)
32. Weilbaecher KN, Guise TA & McCauley LK 2011 Cancer to bone: a fatal attraction. Nature Reviews. Cancer 11 411-425. (doi:10.1038/nrc3055)
33. Yawata A, Adachi M, Okuda H, Naishiro Y, Takamura T, Hareyama M, Takayama S, Reed JC & Imai K 1998 Prolonged cell survival enhances peritoneal dissemination of gastric cancer cells. Oncogene 16 2681-2686. (doi:10.1038/sj.onc.1201792)