The midregion, nuclear localization sequence, and C terminus of PTHrP regulate skeletal development, hematopoiesis, and survival in mice

FASEB Journal

Volumn 24, Issue 6, 2010, Pages 1947-1957

  Toribio, Ramiro E ^a   Brown, Holly A ^a   Novince, Chad M ^b   Marlow, Brandlyn ^a   Hernon, Krista ^a   Lanigan, Lisa G ^a   Hildreth III, Blake E ^a   Werbeck, Jillian L ^a   Shu, Sherry T ^a   Lorch, Gwendolen ^a   Carlton, Michelle ^a   Foley, John ^c   Boyaka, Prosper ^a   McCauley, Laurie K ^b   Rosol, Thomas J ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Craniofacial; Lethality; Osteoblast; Parathyroid

Indexed keywords

BETA CATENIN; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 2A; EPHRIN B2; GLYCOGEN SYNTHASE KINASE 3BETA; PARATHYROID HORMONE RELATED PROTEIN; PARATHYROID HORMONE RELATED PROTEIN[67-137]; PROTEIN; PROTEIN CRTL1; PROTEIN FFG3; PROTEIN OCN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; BONE MASS; BREAST DEVELOPMENT; CARBOXY TERMINAL SEQUENCE; CARTILAGE CELL; CELL PROLIFERATION; CHONDRODYSPLASIA; CONTROLLED STUDY; CRANIOFACIAL MALFORMATION; DOWN REGULATION; ENERGY METABOLISM; ERYTHROID CELL; FEMALE; GENE EXPRESSION; GENOTYPE; HEMATOPOIESIS; KYPHOSIS; MALE; MOUSE; NEWBORN; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OSTEOBLAST; OSTEOCLASTOGENESIS; PRIORITY JOURNAL; SURVIVAL;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BONE AND BONES; CHONDROCYTES; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE KNOCK-IN TECHNIQUES; GENES, LETHAL; HEMATOPOIESIS; IMMUNOENZYME TECHNIQUES; MALE; MAMMARY GLANDS, ANIMAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEAR LOCALIZATION SIGNALS; OSTEOBLASTS; PARATHYROID HORMONE-RELATED PROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SURVIVAL RATE;

MUS;

EID: 77953533775     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-147033     Document Type: Article

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