Analysis of gene expression in PTHrP-/- mammary buds supports a role for BMP signaling and MMP2 in the initiation of ductal morphogenesis

Developmental Dynamics

Volumn 238, Issue 11, 2009, Pages 2713-2724

  Hens, Julie ^a   Dann, Pamela ^b   Hiremath, Minoti ^b   Pan, Tien Chi ^c   Chodosh, Lewis ^c   Wysolmerski, John ^b  

^a ST BONAVENTURE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Ductal morphogenesis; Epidermal appendage; Mammary development; Matrix metalloproteinase; Oligonucleotide gene arrays; Parathyroid hormone related protein

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; BONE MORPHOGENETIC PROTEIN; COLLAGEN TYPE 9; CYTOKERATIN 13; CYTOKERATIN 18; CYTOKERATIN 19; CYTOKERATIN 4; CYTOKERATIN 6; CYTOKERATIN 8; ENTACTIN; GELATINASE A; HIGH MOBILITY GROUP A2 PROTEIN; INHIBITOR OF DIFFERENTIATION 1; MACROPHAGE MIGRATION INHIBITION FACTOR; NEUROPILIN; PARATHYROID HORMONE RELATED PROTEIN; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PLEIOTROPHIN; THROMBOSPONDIN 1; TRANSCRIPTION FACTOR FLI 1; TRANSCRIPTION FACTOR SOX4;

ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN GENE; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; ASPORIN GENE; BASIC TRANSCRIPTION FACTOR 3 GENE; BREAST DEVELOPMENT; BREAST DUCT; BSPONDIN 1 GENE; COLLAGEN TYPE IX ALPHA 1 GENE; CONTROLLED STUDY; DOWN-REGULATOR OF TRANSCRIPTION 1 GENE; EGF LIKE DOMAIN MULTIPLE 6 GENE; EMBRYO; EMBRYO DEVELOPMENT; ENHANCER OF YELLOW 2 HOMOLOG GENE; ENZYME ACTIVITY; EPIDERMAL GROWTH FACTOR CONTAINING FIBULIN LIKE EXTRACELLULAR MATRIX PROTEIN 1 GENE; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; HIGH MOTILITY GROUP AT HOOK 2 GENE; INHIBITOR OF DNA BINDING 4 GENE; IROQUOIS RELATED HOMEOBOX 5 GENE; IROQUOIS RELATED HOMEOBOX 6 GENE; KIT ONCOGENE; MATRILIN 2 GENE; MEIS HOMEOBOX 2 GENE; MESENCHYME CELL; MINICHROMOSOME MAINTENANCE DEFICIENT 6 GENE; MOUSE; NEPHROBLASTOMA OVEREXPRESSED GENE; NONHUMAN; ONCOGENE MYB; OVO HOMOLOG LIKE 1 GENE; PATCHED HOMOLOG 1 GENE; PRIORITY JOURNAL; REVERSION INDUCING CYSTEINE RICH PROTEIN WITH KAZAL MOTIF GENE; RSPONDIN HOMOLOG GENE; SCLEROSTIN DOMAIN CONTAINING 1 GENE; SIGNAL TRANSDUCTION; SINGLE MINDED 2 GENE; SRY BOX CONTAINING GENE 4; T BOX 3 GENE; TACHYKININ 1 GENE; TRANSCRIPTION FACTOR 4 GENE; WNT INHIBITORY FACTOR 1 GENE; WNT1 INDUCIBLE SIGNALING PATHWAY PROTEIN 1 GENE;

ANIMALS; BONE MORPHOGENETIC PROTEIN 4; CELLS, CULTURED; DIPEPTIDES; DOWN-REGULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HYDROXAMIC ACIDS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATINS; MAMMARY GLANDS, ANIMAL; MATRIX METALLOPROTEINASE 2; MESODERM; MICE; MICE, KNOCKOUT; MORPHOGENESIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARATHYROID HORMONE-RELATED PROTEIN; PROTEASE INHIBITORS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 70350705974     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22097     Document Type: Article

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