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Volumn 153, Issue 2, 2012, Pages 861-872

c-myc and skp2 coordinate p27 degradation, vascular smooth muscle proliferation, and neointima formation induced by the parathyroid hormone-related protein

Author keywords

[No Author keywords available]

Indexed keywords

MYC PROTEIN; PARATHYROID HORMONE RELATED PROTEIN; PROTEIN P27; S PHASE KINASE ASSOCIATED PROTEIN 2; SMALL INTERFERING RNA;

EID: 84856090603     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1590     Document Type: Article
Times cited : (23)

References (42)
  • 1
    • 0034595296 scopus 로고    scopus 로고
    • Differential effects of the cyclin-dependent kinase inhibitors p27(Kip1), p21(Cip1) and p16(Ink4) on vascular smooth muscle cell proliferation
    • Tanner FC, Boehm M, Akyürek LM, San H, Yang ZY, Tashiro J, Nabel GJ, Nabel EG 2000 Differential effects of the cyclin-dependent kinase inhibitors p27(KIP1), p21(Cip1), and p16(Ink4) on vascular smooth muscle cell proliferation. Circulation 101:2022-2025 (Pubitemid 30233162)
    • (2000) Circulation , vol.101 , Issue.17 , pp. 2022-2025
    • Tanner, F.C.1    Boehm, M.2    Akyurek, L.M.3    San, H.4    Yang, Z.-Y.5    Tashiro, J.6    Nabel, G.J.7    Nabel, E.G.8
  • 6
    • 41149150219 scopus 로고    scopus 로고
    • The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy
    • DOI 10.1038/nrc2347, PII NRC2347
    • Chu IM, Hengst L, Slingerland JM 2008 The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy. Nat Rev Cancer 8:253-267 (Pubitemid 351430863)
    • (2008) Nature Reviews Cancer , vol.8 , Issue.4 , pp. 253-267
    • Chu, I.M.1    Hengst, L.2    Slingerland, J.M.3
  • 8
    • 0030847760 scopus 로고    scopus 로고
    • Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27(Kip1)
    • DOI 10.1093/emboj/16.17.5334
    • Vlach J, Hennecke S, Amati B 1997 Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27kip1. EMBO J 16:5334-5344 (Pubitemid 27380141)
    • (1997) EMBO Journal , vol.16 , Issue.17 , pp. 5334-5344
    • Vlach, J.1    Hennecke, S.2    Amati, B.3
  • 10
    • 33745050483 scopus 로고    scopus 로고
    • Altered S-phase kinase-associated protein-2 levels are a major mediator of cyclic nucleotide-induced inhibition of vascular smooth muscle cell proliferation
    • DOI 10.1126/science.1121513, PII 0000301220060512000009
    • Wu YJ, Bond M, Sala-Newby GB, Newby AC 2006 Altered S-phase kinase-associated protein-2 levels are a major mediator of cyclic nucleotide-induced inhibition of vascular smooth muscle cell proliferation. Circ Res 98:1141-1150 (Pubitemid 43948100)
    • (2006) Circulation Research , vol.98 , Issue.9 , pp. 1141-1150
    • Wu, Y.-J.1    Bond, M.2    Sala-Newby, G.B.3    Newby, A.C.4
  • 11
    • 54149099613 scopus 로고    scopus 로고
    • Rho GTPase, Rac1, regulates Skp2 levels, vascular smooth muscle cell proliferation, and intima formation in vitro and in vivo
    • Bond M, Wu YJ, Sala-Newby GB, Newby AC 2008 Rho GTPase, Rac1, regulates Skp2 levels, vascular smooth muscle cell proliferation, and intima formation in vitro and in vivo. Cardiovasc Res 80:290-298
    • (2008) Cardiovasc Res , vol.80 , pp. 290-298
    • Bond, M.1    Wu, Y.J.2    Sala-Newby, G.B.3    Newby, A.C.4
  • 12
    • 70350772290 scopus 로고    scopus 로고
    • S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo
    • Wu YJ, Sala-Newby GB, Shu KT, Yeh HI, Nakayama KI, Nakayama K, Newby AC, Bond M 2009 S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo. J Vasc Surg 50:1135-1142
    • (2009) J Vasc Surg , vol.50 , pp. 1135-1142
    • Wu, Y.J.1    Sala-Newby, G.B.2    Shu, K.T.3    Yeh, H.I.4    Nakayama, K.I.5    Nakayama, K.6    Newby, A.C.7    Bond, M.8
  • 13
    • 0032905924 scopus 로고    scopus 로고
    • c-Myc target genes involved in cell growth, apoptosis, and metabolism
    • Dang CV 1999 c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol 19:1-11 (Pubitemid 29018404)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.1 , pp. 1-11
    • Dang, C.V.1
  • 14
    • 0035895632 scopus 로고    scopus 로고
    • Making decisions through Myc
    • DOI 10.1016/S0014-5793(01)02118-4, PII S0014579301021184
    • Nasi S, Ciarapica R, Jucker R, Rosati J, Soucek L 2001 Making decisions through Myc. FEBS Lett 490:153-162 (Pubitemid 32171934)
    • (2001) FEBS Letters , vol.490 , Issue.3 , pp. 153-162
    • Nasi, S.1    Ciarapica, R.2    Jucker, R.3    Rosati, J.4    Soucek, L.5
  • 15
    • 0028219485 scopus 로고
    • Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc antisense oligodeoxynucleotides
    • Bennett MR, Anglin S, McEwan JR, Jagoe R, Newby AC, Evan GI 1994 Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc antisense oligodeoxynucleotides. J Clin Invest 93:820-828 (Pubitemid 24072825)
    • (1994) Journal of Clinical Investigation , vol.93 , Issue.2 , pp. 820-828
    • Bennett, M.R.1    Anglin, S.2    McEwan, J.R.3    Jagoe, R.4    Newby, A.C.5    Evan, G.I.6
  • 22
    • 0031456826 scopus 로고    scopus 로고
    • Opposing mitogenic and anti-mitogenic actions of parathyroid hormone-related protein in vascular smooth muscle cells: A critical role for nuclear targeting
    • Massfelder T, Dann P, Wu TL, Vasavada R, Helwig JJ, Stewart AF 1997 Opposing mitogenic and anti-mitogenic actions of parathyroid hormone-related protein in vascular smooth muscle cells: a critical role for nuclear targeting. Proc Natl Acad Sci USA 94:13630-13635
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 13630-13635
    • Massfelder, T.1    Dann, P.2    Wu, T.L.3    Vasavada, R.4    Helwig, J.J.5    Stewart, A.F.6
  • 23
    • 0034864296 scopus 로고    scopus 로고
    • The C-terminal region of PTHrP, in addition to the nuclear localization signal, is essential for the intracrine stimulation of proliferation in vascular smooth muscle cells
    • DOI 10.1210/en.142.9.4096
    • de Miguel F, Fiaschi-Taesch N, López-Talavera JC, Takane KK, Massfelder T, Helwig JJ, Stewart AF 2001 The C-terminal region of PTHrP, in addition to the nuclear localization signal, is essential for the intracrine stimulation of proliferation in vascular smooth muscle cells. Endocrinology 142:4096-4105 (Pubitemid 32802683)
    • (2001) Endocrinology , vol.142 , Issue.9 , pp. 4096-4105
    • De Miguel, F.1    Fiaschi-Taesch, N.2    Lopez-Talavera, J.C.3    Takane, K.K.4    Massfelder, T.5    Helwig, J.-J.6    Stewart, A.F.7
  • 24
    • 0031803402 scopus 로고    scopus 로고
    • The nucleus: A target site for parathyroid hormone-related peptide (PTHrP) action
    • DOI 10.1002/(SICI)1097-4644(19980801)70:2<193::AID-JCB5>3.0.CO;2-J
    • Nguyen MT, Karaplis AC 1998 The nucleus: a target site for parathyroid hormone-related peptide (PTHrP) action. J Cell Biochem 70:193-199 (Pubitemid 28308928)
    • (1998) Journal of Cellular Biochemistry , vol.70 , Issue.2 , pp. 193-199
    • Nguyen, M.T.A.1    Karaplis, A.C.2
  • 26
    • 3142782107 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein as a regulator of pRb and the cell cycle in arterial smooth muscle
    • DOI 10.1161/01.CIR.0000134483.30849.B7
    • Fiaschi-Taesch N, Takane KK, Masters S, Lopez-Talavera JC, Stewart AF 2004 Parathyroid hormone-related protein as a regulator of pRb and the cell cycle in arterial smooth muscle. Circulation 110:177-185 (Pubitemid 38924586)
    • (2004) Circulation , vol.110 , Issue.2 , pp. 177-185
    • Fiaschi-Taesch, N.1    Takane, K.K.2    Masters, S.3    Lopez-Talavera, J.C.4    Stewart, A.F.5
  • 27
    • 33750474119 scopus 로고    scopus 로고
    • Cellular mechanism through which parathyroid hormone-related protein induces proliferation in arterial smooth muscle cells: Definition of an arterial smooth muscle PTHrP/p27kip1 pathway
    • DOI 10.1161/01.RES.0000248184.21644.20, PII 0000301220061027000006
    • Fiaschi-Taesch N, Sicari BM, Ubriani K, Bigatel T, Takane KK, Cozar-Castellano I, Bisello A, Law B, Stewart AF 2006 Cellular mechanism through which parathyroid hormone-related protein induces proliferation in arterial smooth muscle cells: definition of an arterial smooth muscle PTHrP/p27kip1 pathway. Circ Res 99:933-942 (Pubitemid 44657796)
    • (2006) Circulation Research , vol.99 , Issue.9 , pp. 933-942
    • Fiaschi-Taesch, N.1    Sicari, B.M.2    Ubriani, K.3    Bigatel, T.4    Takane, K.K.5    Cozar-Castellano, I.6    Bisello, A.7    Law, B.8    Stewart, A.F.9
  • 28
    • 62749129408 scopus 로고    scopus 로고
    • Mutant parathyroid hormone-related protein, devoid of the nuclear localization signal, markedly inhibits arterial smooth muscle cell cycle and neointima formation by coordinate up-regulation of p15Ink4b and p27kip1
    • Fiaschi-Taesch N, Sicari B, Ubriani K, Cozar-Castellano I, Takane KK, Stewart AF 2009 Mutant parathyroid hormone-related protein, devoid of the nuclear localization signal, markedly inhibits arterial smooth muscle cell cycle and neointima formation by coordinate up-regulation of p15Ink4b and p27kip1. Endocrinology 150:1429-1439
    • (2009) Endocrinology , vol.150 , pp. 1429-1439
    • Fiaschi-Taesch, N.1    Sicari, B.2    Ubriani, K.3    Cozar-Castellano, I.4    Takane, K.K.5    Stewart, A.F.6
  • 30
    • 0035043115 scopus 로고    scopus 로고
    • Tissue-specific targeting of the Pthrp gene: The generation of mice with floxed alleles
    • DOI 10.1210/en.142.5.2070
    • He B, Deckelbaum RA, Miao D, Lipman ML, Pollak M, Goltzman D, Karaplis AC 2001 Tissue-specific targeting of the pthrp gene: the generation of mice with floxed alleles. Endocrinology 142:2070-2077 (Pubitemid 32405966)
    • (2001) Endocrinology , vol.142 , Issue.5 , pp. 2070-2077
    • He, B.1    Deckelbaum, R.A.2    Miao, D.3    Lipman, M.L.4    Pollak, M.5    Goltzman, D.6    Karaplis, A.C.7
  • 34
    • 0027978302 scopus 로고
    • Transcatheter delivery of c-myc antisense oligomers reduces neointimal formation in a porcine model of coronary artery balloon injury
    • Shi Y, Fard A, Galeo A, Hutchinson HG, Vermani P, Dodge GR, Hall DJ, Shaheen F, Zalewski A 1994 Transcatheter delivery of c-myc antisense oligomers reduces neointimal formation in a porcine model of coronary artery balloon injury. Circulation 90:944-951
    • (1994) Circulation , vol.90 , pp. 944-951
    • Shi, Y.1    Fard, A.2    Galeo, A.3    Hutchinson, H.G.4    Vermani, P.5    Dodge, G.R.6    Hall, D.J.7    Shaheen, F.8    Zalewski, A.9
  • 35
    • 33746794978 scopus 로고    scopus 로고
    • 2-Methoxyestradiol, an estradiol metabolite, inhibits neointima formation and smooth muscle cell growth via double blockade of the cell cycle
    • DOI 10.1161/01.RES.0000233318.85181.2e, PII 0000301220060804000010
    • Barchiesi F, Jackson EK, Fingerle J, Gillespie DG, Odermatt B,Dubey RK 2006 2-Methoxyestradiol, an estradiol metabolite, inhibits neointima formation and smooth muscle cell growth via double blockade of the cell cycle. Circ Res 99:266-274 (Pubitemid 44174934)
    • (2006) Circulation Research , vol.99 , Issue.3 , pp. 266-274
    • Barchiesi, F.1    Jackson, E.K.2    Fingerle, J.3    Gillespie, D.G.4    Odermatt, B.5    Dubey, R.K.6
  • 36
    • 0027985645 scopus 로고
    • Mithramycin inhibits myointimal proliferation after balloon injury of the rat carotid artery in vivo
    • Chen SJ, Chen YF, Miller DM, Li H, Oparil S 1994 Mithramycin inhibits myointimal proliferation after balloon injury of the rat carotid artery in vivo. Circulation 90:2468-2473 (Pubitemid 24354335)
    • (1994) Circulation , vol.90 , Issue.5 , pp. 2468-2473
    • Chen, S.-J.1    Chen, Y.-F.2    Miller, D.M.3    Li, H.4    Oparil, S.5
  • 38
    • 41149141967 scopus 로고    scopus 로고
    • Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer
    • DOI 10.1002/cncr.23317
    • Hershko DD 2008 Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer. Cancer 112:1415-1424 (Pubitemid 351441154)
    • (2008) Cancer , vol.112 , Issue.7 , pp. 1415-1424
    • Hershko, D.D.1
  • 41
    • 28544449224 scopus 로고    scopus 로고
    • Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase
    • DOI 10.1128/MCB.25.24.10875-10894.2005
    • Wang IC, Chen YJ, Hughes D, Petrovic V, Major ML, Park HJ, Tan Y, Ackerson T, Costa RH 2005 Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. Mol Cell Biol 25:10875-10894 (Pubitemid 41747132)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.24 , pp. 10875-10894
    • Wang, I.-C.1    Chen, Y.-J.2    Hughes, D.3    Petrovic, V.4    Major, M.L.5    Park, H.J.6    Tan, Y.7    Ackerson, T.8    Costa, R.H.9
  • 42
    • 13944281061 scopus 로고    scopus 로고
    • FoxM1 dances with mitosis
    • DOI 10.1038/ncb0205-108
    • Costa RH 2005 FoxM1 dances with mitosis. Nat Cell Biol 7:108-110 (Pubitemid 40268125)
    • (2005) Nature Cell Biology , vol.7 , Issue.2 , pp. 108-110
    • Costa, R.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.