Uncaria rhynchophylla and rhynchophylline improved kainic acid-induced epileptic seizures via IL-1β and brain-derived neurotrophic factor

Phytomedicine

Volumn 21, Issue 6, 2014, Pages 893-900

  Ho, Tin Yun ^a   Tang, Nou Ying ^b   Hsiang, Chien Yun ^a   Hsieh, Ching Liang ^b,c  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Brain derived neurotrophic factor; Epileptic seizure; Interleukin 1 ; Rhynchophylline; Uncaria rhynchophylla

Indexed keywords

ANTICONVULSIVE AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 1BETA; KAINIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; NEUROTROPHIN; NUCLEAR FACTOR; PLANT EXTRACT; PROTEIN FOS; RHYNCHOPHYLLINE; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR; UNCARIA RHYNCHOPHYLLA EXTRACT; UNCLASSIFIED DRUG; VALPROIC ACID; INDOLE ALKALOID; RHYNCOPHYLLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DOWN REGULATION; DRUG TARGETING; ELECTROENCEPHALOGRAM; ELECTROMYOGRAM; GENE EXPRESSION REGULATION; GENOMICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SEIZURE; SIGNAL TRANSDUCTION; UNCARIA; UNCARIA RHYNCHOPHYLLA; UPREGULATION; ANIMAL; BRAIN; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; EPILEPSY; GENE EXPRESSION; METABOLISM; PHYTOTHERAPY; SPRAGUE DAWLEY RAT;

RATTUS; UNCARIA RHYNCHOPHYLLA;

ANIMALS; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; EPILEPSY; GENE EXPRESSION; INDOLE ALKALOIDS; INTERLEUKIN-1BETA; KAINIC ACID; MALE; PHYTOTHERAPY; PLANT EXTRACTS; RATS, SPRAGUE-DAWLEY; TOLL-LIKE RECEPTORS; UNCARIA;

EID: 84901197524     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2014.01.011     Document Type: Article

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